Advances in the understanding of the structure-function relationship in Cu,Zn superoxide dismutase.

The structural biochemistry of the superoxide dismutases. Biochim Biophys Acta (2009) 1.50

Role of conserved tyrosine residues in NiSOD catalysis: a case of convergent evolution. Biochemistry (2009) 1.05

Kinetic and spectroscopic studies on a superoxide dismutase from Propionibacterium shermanii that is active with iron or manganese: pH-dependence. Biochem J (1995) 0.80

Complete nucleotide sequence of an influenza virus haemagglutinin gene from cloned DNA. Nature (1979) 7.15

Human growth hormone: complementary DNA cloning and expression in bacteria. Science (1979) 3.67

Faster superoxide dismutase mutants designed by enhancing electrostatic guidance. Nature (1992) 3.56

Synthesis of hepatitis B surface and core antigens in E. coli. Nature (1981) 3.11

Loss of in vitro metal ion binding specificity in mutant copper-zinc superoxide dismutases associated with familial amyotrophic lateral sclerosis. J Biol Chem (2000) 2.05

Recombinant polypeptide from the endonuclease region of the acquired immune deficiency syndrome retrovirus polymerase (pol) gene detects serum antibodies in most infected individuals. J Virol (1986) 2.04

Atomic structures of wild-type and thermostable mutant recombinant human Cu,Zn superoxide dismutase. Proc Natl Acad Sci U S A (1992) 2.02

The structure of human mitochondrial manganese superoxide dismutase reveals a novel tetrameric interface of two 4-helix bundles. Cell (1992) 1.91

Cu/Zn superoxide dismutase mutants associated with amyotrophic lateral sclerosis show enhanced formation of aggregates in vitro. Proc Natl Acad Sci U S A (2003) 1.81

Sequence of a cDNA coding for human glutathione peroxidase confirms TGA encodes active site selenocysteine. Nucleic Acids Res (1987) 1.74

Structure of genes for human growth hormone and chorionic somatomammotropin. Proc Natl Acad Sci U S A (1979) 1.71

High spin cobalt(II) as a probe for the investigation of metalloproteins. Adv Inorg Biochem (1984) 1.61

Human Cu/Zn superoxide dismutase cDNA: isolation of clones synthesising high levels of active or inactive enzyme from an expression library. Nucleic Acids Res (1985) 1.52

Evolution of CuZn superoxide dismutase and the Greek key beta-barrel structural motif. Proteins (1989) 1.52

Synthesis in yeast of a functional oxidation-resistant mutant of human alpha-antitrypsin. Nature (1984) 1.46

cDNA sequence coding for human kidney catalase. Nucleic Acids Res (1986) 1.43

Contribution of conformational stability and reversibility of unfolding to the increased thermostability of human and bovine superoxide dismutase mutated at free cysteines. J Biol Chem (1990) 1.41

First steps towards effective methods in exploiting high-throughput technologies for the determination of human protein structures of high biomedical value. Acta Crystallogr D Biol Crystallogr (2006) 1.40

Solution structure of oxidized horse heart cytochrome c. Biochemistry (1997) 1.39

Cu,Zn superoxide dismutase is a peroxisomal enzyme in human fibroblasts and hepatoma cells. Proc Natl Acad Sci U S A (1991) 1.37

Solution structure of the Cu(I) and apo forms of the yeast metallochaperone, Atx1. Biochemistry (2001) 1.30

Human copper-zinc superoxide dismutase complements superoxide dismutase-deficient Escherichia coli mutants. J Biol Chem (1987) 1.29

Plasmid vectors containing the tryptophan operon promoter suitable for efficient regulated expression of foreign genes. Gene (1980) 1.28

Two-dimensional nuclear magnetic resonance spectra of paramagnetic systems. Methods Enzymol (1994) 1.23

The role of arginine 143 in the electrostatics and mechanism of Cu,Zn superoxide dismutase: computational and experimental evaluation by mutational analysis. Proteins (1994) 1.23

Examination of the nickel site structure and reaction mechanism in Streptomyces seoulensis superoxide dismutase. Biochemistry (1999) 1.22

Characterization of the binding interface between the copper chaperone Atx1 and the first cytosolic domain of Ccc2 ATPase. J Biol Chem (2001) 1.22

Solution structure of reduced monomeric Q133M2 copper, zinc superoxide dismutase (SOD). Why is SOD a dimeric enzyme?. Biochemistry (1998) 1.21

Solution structure of reduced horse heart cytochrome c. J Biol Inorg Chem (1999) 1.21

Expression and processing of biologically active fibroblast growth factors in the yeast Saccharomyces cerevisiae. J Biol Chem (1988) 1.21

Dynamic nuclear polarization at high magnetic fields in liquids. Prog Nucl Magn Reson Spectrosc (2011) 1.19

Magnetic susceptibility tensor anisotropies for a lanthanide ion series in a fixed protein matrix. J Am Chem Soc (2001) 1.19

Pseudocontact shifts as constraints for energy minimization and molecular dynamics calculations on solution structures of paramagnetic metalloproteins. Proteins (1997) 1.19

Superoxide mediates the toxicity of paraquat for cultured mammalian cells. J Biol Chem (1988) 1.18

Isolation and characterization of Co1E2 plasmid mutants unable to kill colicin-sensitive cells. Mol Gen Genet (1976) 1.16

Selenocysteine's mechanism of incorporation and evolution revealed in cDNAs of three glutathione peroxidases. Protein Eng (1988) 1.15

Crystal structure of Y34F mutant human mitochondrial manganese superoxide dismutase and the functional role of tyrosine 34. Biochemistry (1998) 1.13

Changes in crystallographic structure and thermostability of a Cu,Zn superoxide dismutase mutant resulting from the removal of a buried cysteine. J Biol Chem (1990) 1.12

Ab initio solution and refinement of two high-potential iron protein structures at atomic resolution. Acta Crystallogr D Biol Crystallogr (1999) 1.09

Protein effects on the electronic structure of the [Fe4S4]2+ cluster in ferredoxin and HiPIP. J Am Chem Soc (2001) 1.08

SPINE bioinformatics and data-management aspects of high-throughput structural biology. Acta Crystallogr D Biol Crystallogr (2006) 1.08

Anthropometric features and body composition of young athletes practicing karate at a high and medium competitive level. Acta Diabetol (2003) 1.07

A spectroscopic characterization of a monomeric analog of copper, zinc superoxide dismutase. Eur Biophys J (1994) 1.07

Copper trafficking: the solution structure of Bacillus subtilis CopZ. Biochemistry (2001) 1.07

Structure, exon pattern, and chromosome mapping of the gene for cytosolic copper-zinc superoxide dismutase (sod-1) from Neurospora crassa. J Biol Chem (1990) 1.06

Human mitochondrial manganese superoxide dismutase polymorphic variant Ile58Thr reduces activity by destabilizing the tetrameric interface. Biochemistry (1996) 1.05

Crystallographic characterization of recombinant human CuZn superoxide dismutase. J Biol Chem (1986) 1.05

The crystal structure of the monomeric human SOD mutant F50E/G51E/E133Q at atomic resolution. The enzyme mechanism revisited. J Mol Biol (1999) 1.05

Heme methyl 1H chemical shifts as structural parameters in some low-spin ferriheme proteins. J Biol Inorg Chem (1999) 1.04

A characterization of copper/zinc superoxide dismutase mutants at position 124. Zinc-deficient proteins. Eur J Biochem (1991) 1.03

Solution structure of oxidized microsomal rabbit cytochrome b5. Factors determining the heterogeneous binding of the heme. Eur J Biochem (2000) 1.03

Isolation and properties of recombinant DNA produced variants of human alpha 1-proteinase inhibitor. J Biol Chem (1985) 1.03

Proton NMR investigation into the basis for the relatively high redox potential of lignin peroxidase. Proc Natl Acad Sci U S A (1991) 1.02

Solution structure of the paramagnetic complex of the N-terminal domain of calmodulin with two Ce3+ ions by 1H NMR. Biochemistry (1997) 1.02

Solution structure of oxidized Saccharomyces cerevisiae iso-1-cytochrome c. Biochemistry (1997) 1.01

Structural properties of peroxidases. J Biotechnol (1997) 1.01

Mitochondrial cytochromes c: a comparative analysis. J Biol Inorg Chem (1999) 1.01

The solution structure of oxidized Escherichia coli cytochrome b562. Biochemistry (1999) 1.01

Three-dimensional solution structure of Saccharomyces cerevisiae reduced iso-1-cytochrome c. Biochemistry (1996) 1.00

Identification of a serum-detectable metabolomic fingerprint potentially correlated with the presence of micrometastatic disease in early breast cancer patients at varying risks of disease relapse by traditional prognostic methods. Ann Oncol (2011) 0.99

Images of asteroid 21 Lutetia: a remnant planetesimal from the early Solar System. Science (2011) 0.99

Backbone dynamics of human Cu,Zn superoxide dismutase and of its monomeric F50E/G51E/E133Q mutant: the influence of dimerization on mobility and function. Biochemistry (2000) 0.99

Highlights of current research involving superoxide and perhydroxyl radicals in aqueous solutions. Int J Radiat Biol (1991) 0.99

The mechanism of superoxide scavenging by Archaeoglobus fulgidus neelaredoxin. J Biol Chem (2001) 0.97

Thermostabilization of recombinant human and bovine CuZn superoxide dismutases by replacement of free cysteines. Biochem Biophys Res Commun (1991) 0.96

Solution structure of the yeast copper transporter domain Ccc2a in the apo and Cu(I)-loaded states. J Biol Chem (2000) 0.95

Multiple replacements of glutamine 143 in human manganese superoxide dismutase: effects on structure, stability, and catalysis. Biochemistry (2000) 0.94

The solution structure of parsley [2Fe-2S]ferredoxin. Eur J Biochem (1998) 0.94

Crystal structure of the catalytic domain of human matrix metalloproteinase 10. J Mol Biol (2004) 0.94

Paramagnetic relaxation as a tool for solution structure determination: Clostridium pasteurianum ferredoxin as an example. Proteins (1997) 0.94

Application of the use of high-throughput technologies to the determination of protein structures of bacterial and viral pathogens. Acta Crystallogr D Biol Crystallogr (2006) 0.93

PSEUDYANA for NMR structure calculation of paramagnetic metalloproteins using torsion angle molecular dynamics. J Biomol NMR (1998) 0.93

Reactions of hydrogen peroxide with familial amyotrophic lateral sclerosis mutant human copper-zinc superoxide dismutases studied by pulse radiolysis. J Biol Chem (1998) 0.93

Identification of localized redox states in plant-type two-iron ferredoxins using the nuclear Overhauser effect. Biochemistry (1990) 0.92

Clinical and functional investigation of 10 missense mutations and a novel frameshift insertion mutation of the gene for copper-zinc superoxide dismutase in UK families with amyotrophic lateral sclerosis. Neurology (1997) 0.92