Published in Science on October 28, 2011
Human gene mutation database-a biomedical information and research resource. Hum Mutat (2000) 6.87
Effects of a polypill (Polycap) on risk factors in middle-aged individuals without cardiovascular disease (TIPS): a phase II, double-blind, randomised trial. Lancet (2009) 6.83
Matching using estimated propensity scores: relating theory to practice. Biometrics (1996) 6.73
Psychometric properties of the National Eye Institute Visual Function Questionnaire (NEI-VFQ). NEI-VFQ Field Test Investigators. Arch Ophthalmol (1998) 5.64
Clinical progression and virological failure on highly active antiretroviral therapy in HIV-1 patients: a prospective cohort study. Swiss HIV Cohort Study. Lancet (1999) 4.83
Live attenuated malaria vaccine designed to protect through hepatic CD8⁺ T cell immunity. Science (2011) 4.72
Acute and subacute rehabilitation for stroke: a comparison. Arch Phys Med Rehabil (1995) 4.20
Nonspecific acid esterase activity: a criterion for differentiation of T and B lymphocytes in mouse lymph nodes. Eur J Immunol (1975) 4.16
Characterization of V3 sequence heterogeneity in subtype C human immunodeficiency virus type 1 isolates from Malawi: underrepresentation of X4 variants. J Virol (1999) 4.16
Analysis of deletions in DNA from patients with Becker and Duchenne muscular dystrophy. Nature (1986) 4.13
X-linked anhidrotic (hypohidrotic) ectodermal dysplasia is caused by mutation in a novel transmembrane protein. Nat Genet (1996) 3.90
Discovery of a cool planet of 5.5 Earth masses through gravitational microlensing. Nature (2006) 3.53
AIDS-related opportunistic illnesses occurring after initiation of potent antiretroviral therapy: the Swiss HIV Cohort Study. JAMA (1999) 3.34
Calprotectin is a stronger predictive marker of relapse in ulcerative colitis than in Crohn's disease. Gut (2005) 3.31
HIV viral load response to antiretroviral therapy according to the baseline CD4 cell count and viral load. JAMA (2001) 2.95
Search for a resonance decaying into WZ boson pairs in pp collisions. Phys Rev Lett (2010) 2.83
Role of faecal calprotectin as non-invasive marker of intestinal inflammation. Dig Liver Dis (2003) 2.79
Linkage disequilibrium fine mapping and haplotype association analysis of the tau gene in progressive supranuclear palsy and corticobasal degeneration. J Med Genet (2005) 2.56
Interpreting hospital mortality data. The role of clinical risk adjustment. JAMA (1989) 2.53
Limb-salvage treatment versus amputation for osteosarcoma of the distal end of the femur. J Bone Joint Surg Am (1986) 2.49
Treatment of acute myocardial infarction with anisoylated plasminogen streptokinase activator complex. Br Med J (Clin Res Ed) (1986) 2.33
Plasmodium vivax clinically resistant to chloroquine in Colombia. Am J Trop Med Hyg (2001) 2.30
D2 dopamine receptor gene (DRD2) Taq1 A polymorphism: reduced dopamine D2 receptor binding in the human striatum associated with the A1 allele. Pharmacogenetics (1997) 2.28
Fault lubrication during earthquakes. Nature (2011) 2.28
Reflux pattern and role of impedance-pH variables in predicting PPI response in patients with suspected GERD-related chronic cough. Aliment Pharmacol Ther (2014) 2.27
Correlation between morphological and functional retinal impairment in multiple sclerosis patients. Invest Ophthalmol Vis Sci (1999) 2.27
An absence of cutaneous neurofibromas associated with a 3-bp inframe deletion in exon 17 of the NF1 gene (c.2970-2972 delAAT): evidence of a clinically significant NF1 genotype-phenotype correlation. Am J Hum Genet (2006) 2.23
In vitro differentiation of Trypanosoma cruzi under chemically defined conditions. Mol Biochem Parasitol (1985) 2.20
Ballooning of the levator hiatus. Ultrasound Obstet Gynecol (2008) 2.18
Studies on chemotaxis. I. On the chemotactic and complement-fixing activity of gamma-globulins. Immunology (1965) 2.15
Compliance with do-not-resuscitate orders for hospitalized patients transported to radiology departments. Ann Intern Med (1998) 2.14
Chemotactic reorientation of granulocytes stimulated with micropipettes containing fMet-Leu-Phe. J Cell Sci (1981) 2.12
A controlled study of inhaled pentamidine for primary prevention of Pneumocystis carinii pneumonia. N Engl J Med (1991) 2.10
Re-assessment of Boyden's technique for measuring chemotaxis. J Immunol Methods (1972) 2.05
Very-long-baseline radio interferometry observations of low power radio galaxies. Proc Natl Acad Sci U S A (1995) 2.04
Miltefosine for new world cutaneous leishmaniasis. Clin Infect Dis (2004) 2.02
Prevalence of adverse events associated with potent antiretroviral treatment: Swiss HIV Cohort Study. Lancet (2001) 2.01
Polymerization polarity of actin. J Mechanochem Cell Motil (1976) 1.97
Chlorophyll a Fluorescence and Photosynthetic and Growth Responses of Pinus radiata to Phosphorus Deficiency, Drought Stress, and High CO(2). Plant Physiol (1986) 1.92
Positive and sustained effects of highly active antiretroviral therapy on HIV-1-associated neurocognitive impairment. AIDS (1999) 1.89
A precision measurement of the mass of the top quark. Nature (2004) 1.87
The rubble-pile asteroid Itokawa as observed by Hayabusa. Science (2006) 1.87
Chemotaxis of leucocytes. Experientia (1968) 1.85
Gravitational scattering as a possible origin for giant planets at small stellar distances. Nature (1997) 1.78
Tetanus and diphtheria immunity in an elderly population in Los Angeles County. Am J Public Health (1983) 1.77
Failures of 1 week on, 1 week off antiretroviral therapies in a randomized trial. AIDS (2003) 1.76
Dawn at Vesta: testing the protoplanetary paradigm. Science (2012) 1.76
Adefovir dipivoxil for the treatment of lamivudine-resistant hepatitis B mutants. Hepatology (2000) 1.76
Studies on chemotaxis. XI. Effect on neutrophils of lysosomal and other subcellular fractions from leukocytes. Int Arch Allergy Appl Immunol (1969) 1.73
A closer look at water-related geologic activity on Mars. Science (2007) 1.71
Performance of five different assays for the quantification of viral load in persons infected with various subtypes of HIV-1. Swiss HIV Cohort Study. J Acquir Immune Defic Syndr (2000) 1.69
Vernal keratoconjunctivitis revisited: a case series of 195 patients with long-term followup. Ophthalmology (2000) 1.68
Mineralization of linear alkylbenzene sulfonate by a four-member aerobic bacterial consortium. Appl Environ Microbiol (1991) 1.68
Transverse-momentum and pseudorapidity distributions of charged hadrons in pp collisions at square root of s = 7 TeV. Phys Rev Lett (2010) 1.67
End-of-life care preferences of patients enrolled in cardiovascular rehabilitation programs. Chest (2000) 1.65
Intrahepatic metastatic nodules of hepatocellular carcinoma detected at lipiodol-CT: imaging-pathologic correlation. Abdom Imaging (1997) 1.63
The general practitioner's approach to irritable bowel syndrome: from intention to practice. Dig Liver Dis (2005) 1.62
Long-read sequence analysis of the MECP2 gene in Rett syndrome patients: correlation of disease severity with mutation type and location. Hum Mol Genet (2000) 1.61
High spin cobalt(II) as a probe for the investigation of metalloproteins. Adv Inorg Biochem (1984) 1.61
Double pylorus: report of two cases and review of the literature. Ital J Gastroenterol (1992) 1.60
Quantitation of human immunodeficiency virus type 1 RNA in different biological compartments. J Clin Microbiol (2000) 1.60
Search for supersymmetry using final states with one lepton, jets, and missing transverse momentum with the ATLAS detector in √s=7 TeV pp collisions. Phys Rev Lett (2011) 1.60
Two-hybrid analysis reveals fundamental differences in direct interactions between desmoplakin and cell type-specific intermediate filaments. J Biol Chem (1997) 1.59
Natural history of chronic hepatitis C. Ital J Gastroenterol Hepatol (1999) 1.59
Optical observations of comet Hale-Bopp (C/1995 O1) at large heliocentric distances before perihelion. Science (1997) 1.58
Spectroscopic characterization of mineralogy and its diversity across Vesta. Science (2012) 1.57
Study of the mass and spin-parity of the Higgs boson candidate via its decays to Z boson pairs. Phys Rev Lett (2013) 1.56
miR-145 induces caspase-dependent and -independent cell death in urothelial cancer cell lines with targeting of an expression signature present in Ta bladder tumors. Oncogene (2009) 1.56
Incisional hernia and fascial defect following laparoscopic surgery. Surg Laparosc Endosc Percutan Tech (2000) 1.56
The NEI-VFQ-25 in people with long-term type 1 diabetes mellitus: the Wisconsin Epidemiologic Study of Diabetic Retinopathy. Arch Ophthalmol (2001) 1.55
A proposal for the definition of terms related to locomotion of leucocytes and other cells. Clin Exp Immunol (1977) 1.55
Clinical relevance of cytomegalovirus viraemia(*,†). HIV Med (2011) 1.55
Studies on the regulation of the neutrophil chemotactic response using a rapid and reliable method for measuring random migration and chemotaxis of neutrophil granulocytes. Agents Actions (1976) 1.54
Measurement of the forward-backward charge asymmetry in top-quark pair production. Phys Rev Lett (2008) 1.53
The violent collisional history of asteroid 4 Vesta. Science (2012) 1.52
Assessment of an Interferon-gamma release assay for the diagnosis of latent tuberculosis infection in haemodialysis patient. Swiss Med Wkly (2010) 1.50
Studies on chemotaxis. VI. Specific chemotaxis in rabbit polymorphonuclear leucocytes and mononuclear cells. Int Arch Allergy Appl Immunol (1967) 1.50
Exposed water ice deposits on the surface of comet 9P/Tempel 1. Science (2006) 1.49
Striatal dopaminergic markers in dementia with Lewy bodies, Alzheimer's and Parkinson's diseases: rostrocaudal distribution. Brain (1999) 1.48
Evidence of water vapor in excess of saturation in the atmosphere of Mars. Science (2011) 1.48
Advance directive education during pulmonary rehabilitation. Chest (1996) 1.47
TCTP protects from apoptotic cell death by antagonizing bax function. Cell Death Differ (2008) 1.47
Shwachman syndrome: phenotypic manifestations of sibling sets and isolated cases in a large patient cohort are similar. J Pediatr (1999) 1.47
Cytokine and chemokine levels in systemic sclerosis: relationship with cutaneous and internal organ involvement. Clin Exp Immunol (2004) 1.46
Measurement of the W boson mass with the D0 detector. Phys Rev Lett (2012) 1.46
Serum gamma-glutamyl-transpeptidase isoforms in alcoholic liver disease. Alcohol Alcohol (1997) 1.46
The Glaucoma Symptom Scale. A brief index of glaucoma-specific symptoms. Arch Ophthalmol (1998) 1.46
Microbial DNA profiling by multiplex terminal restriction fragment length polymorphism for forensic comparison of soil and the influence of sample condition. J Appl Microbiol (2008) 1.45
Natural transfer of viable microbes in space. Icarus (2000) 1.45
The dental caries experience of 5-year-old children in Great Britain (2005/6). Surveys co-ordinated by the British Association for the study of community dentistry. Community Dent Health (2007) 1.43
Fludarabine, cytarabine, and granulocyte-colony stimulating factor for the treatment of high risk myelodysplastic syndromes. Cancer (1999) 1.43
Erectile dysfunction in men with and without diabetes mellitus: a comparative study. Diabet Med (1996) 1.43
Observation of a centrality-dependent dijet asymmetry in lead-lead collisions at sqrt[S(NN)] =2.76 TeV with the ATLAS detector at the LHC. Phys Rev Lett (2010) 1.41
Efficacy and safety of topical WBI-1001 in patients with mild to severe atopic dermatitis: results from a 12-week, multicentre, randomized, placebo-controlled double-blind trial. Br J Dermatol (2012) 1.41