Published in J Phys Chem B on March 02, 2006
A kinetic model of trp-cage folding from multiple biased molecular dynamics simulations. PLoS Comput Biol (2009) 1.46
Microsecond simulations of the folding/unfolding thermodynamics of the Trp-cage miniprotein. Proteins (2010) 1.45
A pre-existing hydrophobic collapse in the unfolded state of an ultrafast folding protein. Nature (2007) 1.39
The Trp-cage: optimizing the stability of a globular miniprotein. Protein Eng Des Sel (2008) 1.29
Spectroscopic studies of protein folding: linear and nonlinear methods. Protein Sci (2011) 1.10
Achieving secondary structural resolution in kinetic measurements of protein folding: a case study of the folding mechanism of Trp-cage. Angew Chem Int Ed Engl (2011) 1.05
Thermodynamics of the Trp-cage miniprotein unfolding in urea. Proteins (2010) 0.96
Calculation of the free energy and cooperativity of protein folding. PLoS One (2007) 0.96
Optimal salt bridge for Trp-cage stabilization. Biochemistry (2011) 0.93
Microsecond folding experiments and simulations: a match is made. Phys Chem Chem Phys (2013) 0.91
Microsecond folding dynamics of apomyoglobin at acidic pH. J Phys Chem B (2012) 0.87
Fast protein folding kinetics. Q Rev Biophys (2014) 0.86
Crystal and NMR structures of a Trp-cage mini-protein benchmark for computational fold prediction. Proc Natl Acad Sci U S A (2012) 0.86
Characterization of the cofactor-induced folding mechanism of a zinc-binding peptide using computationally designed mutants. J Mol Biol (2009) 0.85
Fluorescence correlation spectroscopic study of serpin depolymerization by computationally designed peptides. J Mol Biol (2007) 0.85
Computational design of thermostabilizing D-amino acid substitutions. J Am Chem Soc (2011) 0.83
Circular permutation of a WW domain: folding still occurs after excising the turn of the folding-nucleating hairpin. J Am Chem Soc (2014) 0.81
The effect of charge-charge interactions on the kinetics of alpha-helix formation. Biophys J (2007) 0.81
Utility of 5-Cyanotryptophan Fluorescence as a Sensitive Probe of Protein Hydration. J Phys Chem B (2016) 0.80
Computational design and experimental discovery of an antiestrogenic peptide derived from alpha-fetoprotein. J Am Chem Soc (2007) 0.79
Tuning the Attempt Frequency of Protein Folding Dynamics via Transition-State Rigidification: Application to Trp-Cage. J Phys Chem Lett (2015) 0.79
Folding dynamics and pathways of the trp-cage miniproteins. Biochemistry (2014) 0.78
Circular Permutation of the Trp-cage: Fold Rescue upon Addition of a Hydrophobic Staple. RSC Adv (2013) 0.78
Aryl-Aryl interactions in designed peptide folds: Spectroscopic characteristics and placement issues for optimal structure stabilization. Biopolymers (2016) 0.78
Atomic-level structure characterization of an ultrafast folding mini-protein denatured state. PLoS One (2012) 0.76
A Miniature Protein Stabilized by a Cation-π Interaction Network. J Am Chem Soc (2016) 0.76
Optimizing the fold stability of miniprotein sequences. Adv Exp Med Biol (2009) 0.75
A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growth. Cancer Res (2009) 6.15
A GABAergic system in airway epithelium is essential for mucus overproduction in asthma. Nat Med (2007) 2.43
Helix formation via conformation diffusion search. Proc Natl Acad Sci U S A (2002) 2.34
Using nitrile-derivatized amino acids as infrared probes of local environment. J Am Chem Soc (2003) 2.30
Novel plasmid and its variant harboring both a bla(NDM-1) gene and type IV secretion system in clinical isolates of Acinetobacter lwoffii. Antimicrob Agents Chemother (2012) 1.97
Regulation of androgen receptor transcriptional activity and specificity by RNF6-induced ubiquitination. Cancer Cell (2009) 1.77
Metagenome-wide analysis of antibiotic resistance genes in a large cohort of human gut microbiota. Nat Commun (2013) 1.65
Computational design and characterization of a monomeric helical dinuclear metalloprotein. J Mol Biol (2003) 1.60
Ultrafast folding of alpha3D: a de novo designed three-helix bundle protein. Proc Natl Acad Sci U S A (2003) 1.57
The 44-kDa Pim-1 kinase phosphorylates BCRP/ABCG2 and thereby promotes its multimerization and drug-resistant activity in human prostate cancer cells. J Biol Chem (2007) 1.55
Computational de novo design and characterization of a four-helix bundle protein that selectively binds a nonbiological cofactor. J Am Chem Soc (2005) 1.52
A new method for determining the local environment and orientation of individual side chains of membrane-binding peptides. J Am Chem Soc (2004) 1.51
Translational biomarkers of acetaminophen-induced acute liver injury. Arch Toxicol (2015) 1.49
Type I IFNs enhance susceptibility to Chlamydia muridarum lung infection by enhancing apoptosis of local macrophages. J Immunol (2008) 1.49
RNA interference targeting E637K mutation rescues hERG channel currents and restores its kinetic properties. Heart Rhythm (2012) 1.48
IL-17/Th17 promotes type 1 T cell immunity against pulmonary intracellular bacterial infection through modulating dendritic cell function. J Immunol (2009) 1.42
Cholesterol-dependent phase separation in cell-derived giant plasma-membrane vesicles. Biochem J (2009) 1.40
Understanding the key factors that control the rate of beta-hairpin folding. Proc Natl Acad Sci U S A (2004) 1.40
Trp zipper folding kinetics by molecular dynamics and temperature-jump spectroscopy. Proc Natl Acad Sci U S A (2004) 1.39
Dysbiosis signature of fecal microbiota in colorectal cancer patients. Microb Ecol (2013) 1.37
Site-Specific Spectroscopic Reporters of the Local Electric Field, Hydration, Structure, and Dynamics of Biomolecules. J Phys Chem Lett (2011) 1.36
Porous 3D graphene-based bulk materials with exceptional high surface area and excellent conductivity for supercapacitors. Sci Rep (2013) 1.36
Conformational distribution of a 14-residue peptide in solution: a fluorescence resonance energy transfer study. J Phys Chem B (2005) 1.35
Computational design of water-soluble analogues of the potassium channel KcsA. Proc Natl Acad Sci U S A (2004) 1.31
A novel fluorescent probe for protein binding and folding studies: p-cyano-phenylalanine. Biopolymers (2006) 1.27
Theoretical and computational protein design. Annu Rev Phys Chem (2011) 1.26
Computational design of a protein crystal. Proc Natl Acad Sci U S A (2012) 1.23
Probing the folding transition state structure of the villin headpiece subdomain via side chain and backbone mutagenesis. J Am Chem Soc (2009) 1.23
Evolutionary constraints on structural similarity in orthologs and paralogs. Protein Sci (2009) 1.23
Statistical and molecular dynamics studies of buried waters in globular proteins. Proteins (2005) 1.23
Genome-wide analysis revealed the complex regulatory network of brassinosteroid effects in photomorphogenesis. Mol Plant (2009) 1.22
Site-specific hydration status of an amphipathic peptide in AOT reverse micelles. Langmuir (2007) 1.21
Infrared study of the effect of hydration on the amide I band and aggregation properties of helical peptides. J Phys Chem B (2007) 1.21
5-Cyanotryptophan as an Infrared Probe of Local Hydration Status of Proteins. Chem Phys Lett (2009) 1.21
Computational protein design to reengineer stromal cell-derived factor-1α generates an effective and translatable angiogenic polypeptide analog. Circulation (2011) 1.20
NK T cell activation promotes Chlamydia trachomatis infection in vivo. J Immunol (2005) 1.18
Androgen receptor splice variant AR3 promotes prostate cancer via modulating expression of autocrine/paracrine factors. J Biol Chem (2013) 1.18
Resveratrol rescues SIRT1-dependent adult stem cell decline and alleviates progeroid features in laminopathy-based progeria. Cell Metab (2012) 1.18
Using an amino acid fluorescence resonance energy transfer pair to probe protein unfolding: application to the villin headpiece subdomain and the LysM domain. Biochemistry (2008) 1.18
De novo design of a redox-active minimal rubredoxin mimic. J Am Chem Soc (2005) 1.16
The Two Dimensional Vibrational Echo of a Nitrile Probe of the Villin HP35 Protein. J Phys Chem Lett (2010) 1.15
Divalent cation-induced cluster formation by polyphosphoinositides in model membranes. J Am Chem Soc (2012) 1.14
Effect of dehydration on the aggregation kinetics of two amyloid peptides. J Phys Chem B (2009) 1.14
Transmembrane orientation and possible role of the fusogenic peptide from parainfluenza virus 5 (PIV5) in promoting fusion. Proc Natl Acad Sci U S A (2011) 1.14
Directing noble metal ion chemistry within a designed ferritin protein. Biochemistry (2008) 1.12
Infrared study of the stability and folding kinetics of a 15-residue beta-hairpin. J Am Chem Soc (2003) 1.12
A focused antibody library for selecting scFvs expressed at high levels in the cytoplasm. BMC Biotechnol (2007) 1.12
Compensatory upregulation of tyrosine kinase Etk/BMX in response to androgen deprivation promotes castration-resistant growth of prostate cancer cells. Cancer Res (2010) 1.11
Mid- to long-term outcomes after cervical disc arthroplasty compared with anterior discectomy and fusion: a systematic review and meta-analysis of randomized controlled trials. Eur Spine J (2014) 1.11
Spectroscopic studies of protein folding: linear and nonlinear methods. Protein Sci (2011) 1.10
An induced fit mechanism regulates p53 DNA binding kinetics to confer sequence specificity. EMBO J (2011) 1.10
Using two fluorescent probes to dissect the binding, insertion, and dimerization kinetics of a model membrane peptide. J Am Chem Soc (2009) 1.09
Nanosecond folding dynamics of a three-stranded beta-sheet. J Am Chem Soc (2006) 1.09
Folding kinetics of a naturally occurring helical peptide: implication of the folding speed limit of helical proteins. J Phys Chem B (2008) 1.08
Probing the kinetics of membrane-mediated helix folding. J Phys Chem B (2006) 1.08
Role of helix nucleation in the kinetics of binding of mastoparan X to phospholipid bilayers. Biochemistry (2007) 1.08
CREPT accelerates tumorigenesis by regulating the transcription of cell-cycle-related genes. Cancer Cell (2012) 1.07
Effect of macromolecular crowding on protein folding dynamics at the secondary structure level. J Mol Biol (2009) 1.07
Structural coupling between FKBP12 and buried water. Proteins (2009) 1.07
Understanding the mechanism of beta-hairpin folding via phi-value analysis. Biochemistry (2006) 1.06
Limitations of yeast surface display in engineering proteins of high thermostability. Protein Eng Des Sel (2006) 1.06
A Role for OCT4 in Tumor Initiation of Drug-Resistant Prostate Cancer Cells. Genes Cancer (2010) 1.06
Achieving secondary structural resolution in kinetic measurements of protein folding: a case study of the folding mechanism of Trp-cage. Angew Chem Int Ed Engl (2011) 1.05
Phytoplankton community succession shaping bacterioplankton community composition in Lake Taihu, China. Water Res (2011) 1.03
Using alpha-helical coiled-coils to design nanostructured metalloporphyrin arrays. J Am Chem Soc (2008) 1.02
Role of toll-like receptors in immune responses to chlamydial infections. Curr Pharm Des (2008) 1.02
Tuning the cooperativity of the helix-coil transition by aqueous reverse micelles. J Phys Chem B (2006) 1.01
Binding site and affinity prediction of general anesthetics to protein targets using docking. Anesth Analg (2012) 1.01
Computational protein design: structure, function and combinatorial diversity. Curr Opin Chem Biol (2007) 1.01
Transmission-mode diamond white-beam position monitor at NSLS. J Synchrotron Radiat (2012) 1.00
Identification of the active form of endothelial lipase, a homodimer in a head-to-tail conformation. J Biol Chem (2009) 1.00
IL-17R activation of human airway smooth muscle cells induces CXCL-8 production via a transcriptional-dependent mechanism. Clin Immunol (2005) 1.00
Advances in computational protein design. Curr Opin Struct Biol (2004) 0.99
Invariant NKT cells preferentially modulate the function of CD8 alpha+ dendritic cell subset in inducing type 1 immunity against infection. J Immunol (2010) 0.99
Computational design and elaboration of a de novo heterotetrameric alpha-helical protein that selectively binds an emissive abiological (porphinato)zinc chromophore. J Am Chem Soc (2010) 0.99
Photophysics of a Fluorescent Non-natural Amino Acid: p-Cyanophenylalanine. Chem Phys Lett (2010) 0.99
A case-control study provides evidence of association for a common SNP rs974819 in PDGFD to coronary heart disease and suggests a sex-dependent effect. Thromb Res (2012) 0.98
Genomic sequence based scanning for drug resistance-associated mutations and evolutionary analysis of multidrug-resistant and extensively drug-resistant Mycobacterium tuberculosis. J Infect (2012) 0.98
Distinct NKT cell subsets are induced by different Chlamydia species leading to differential adaptive immunity and host resistance to the infections. J Immunol (2007) 0.98
Functional screening of antibiotic resistance genes from human gut microbiota reveals a novel gene fusion. FEMS Microbiol Lett (2012) 0.97
Red and processed meat intake is associated with higher gastric cancer risk: a meta-analysis of epidemiological observational studies. PLoS One (2013) 0.97
Dissecting the membrane binding and insertion kinetics of a pHLIP peptide. Biochemistry (2008) 0.97
Alpha 1-antitrypsin polymerization: a fluorescence correlation spectroscopic study. Biochemistry (2005) 0.97
Natural killer T cells are critical for dendritic cells to induce immunity in Chlamydial pneumonia. Am J Respir Crit Care Med (2008) 0.96
Site-specific infrared probes of proteins. Annu Rev Phys Chem (2015) 0.96
Selective incorporation of nitrile-based infrared probes into proteins via cysteine alkylation. Biochemistry (2010) 0.95
Natural killer T cells contribute to airway eosinophilic inflammation induced by ragweed through enhanced IL-4 and eotaxin production. Eur J Immunol (2004) 0.95
Direct assessment of the α-helix nucleation time. J Phys Chem B (2011) 0.95
Using thioamides to site-specifically interrogate the dynamics of hydrogen bond formation in β-sheet folding. J Am Chem Soc (2012) 0.95
Computational design of membrane proteins. Structure (2012) 0.95
Genome sequence of the Spinosyns-producing bacterium Saccharopolyspora spinosa NRRL 18395. J Bacteriol (2011) 0.95
p15RS attenuates Wnt/{beta}-catenin signaling by disrupting {beta}-catenin·TCF4 Interaction. J Biol Chem (2010) 0.95
Histological features of the gastric mucosa in children with primary bile reflux gastritis. World J Surg Oncol (2012) 0.94
Understanding the folding mechanism of an alpha-helical hairpin. Biochemistry (2006) 0.94
IL-17A synergizes with IFN-γ to upregulate iNOS and NO production and inhibit chlamydial growth. PLoS One (2012) 0.94
Oral cancer development in patients with leukoplakia--clinicopathological factors affecting outcome. PLoS One (2012) 0.94