PubRank

Timothy H Bestor

Author PubWeight™ 101.96‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Eukaryotic cytosine methyltransferases. Annu Rev Biochem 2005 15.45
2 DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA. Nature 2007 11.14
3 The colorful history of active DNA demethylation. Cell 2008 8.50
4 MIWI2 is essential for spermatogenesis and repression of transposons in the mouse male germline. Dev Cell 2007 7.66
5 Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking Dnmt3L. Nature 2004 7.57
6 Large-scale structure of genomic methylation patterns. Genome Res 2005 4.11
7 Methylation of tRNAAsp by the DNA methyltransferase homolog Dnmt2. Science 2006 3.87
8 Methylation dynamics of imprinted genes in mouse germ cells. Genomics 2002 3.19
9 Altered methylation patterns in cancer cell genomes: cause or consequence? Cancer Cell 2002 3.09
10 Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation. Science 2010 2.98
11 Mammalian cytosine methylation at a glance. J Cell Sci 2009 2.43
12 Hyperconserved CpG domains underlie Polycomb-binding sites. Proc Natl Acad Sci U S A 2007 2.41
13 Ascorbic acid prevents loss of Dlk1-Dio3 imprinting and facilitates generation of all-iPS cell mice from terminally differentiated B cells. Nat Genet 2012 2.35
14 Discordant KCNQ1OT1 imprinting in sets of monozygotic twins discordant for Beckwith-Wiedemann syndrome. Hum Mol Genet 2002 2.33
15 Chromatin and sequence features that define the fine and gross structure of genomic methylation patterns. Genome Res 2010 2.25
16 Epigenetic decisions in mammalian germ cells. Science 2007 1.88
17 Computational prediction of methylation status in human genomic sequences. Proc Natl Acad Sci U S A 2006 1.83
18 Extensive meiotic asynapsis in mice antagonises meiotic silencing of unsynapsed chromatin and consequently disrupts meiotic sex chromosome inactivation. J Cell Biol 2008 1.77
19 Dynamics of Dnmt1 methyltransferase expression and intracellular localization during oogenesis and preimplantation development. Dev Biol 2002 1.44
20 Identification of the control region for tissue-specific imprinting of the stimulatory G protein alpha-subunit. Proc Natl Acad Sci U S A 2005 1.43
21 Windows for sex-specific methylation marked by DNA methyltransferase expression profiles in mouse germ cells. Dev Biol 2004 1.41
22 The parental non-equivalence of imprinting control regions during mammalian development and evolution. PLoS Genet 2010 1.41
23 Histone modification and replacement in chromatin activation. Genes Dev 2002 1.38
24 Decatenation checkpoint deficiency in stem and progenitor cells. Cancer Cell 2005 1.34
25 Biological functions of DNA methyltransferase 1 require its methyltransferase activity. Mol Cell Biol 2007 1.27
26 Cytosine methylation: remaining faithful. Curr Biol 2008 1.18
27 BRCA1 promoter methylation is associated with increased mortality among women with breast cancer. Breast Cancer Res Treat 2008 1.16
28 Dynamic instability of genomic methylation patterns in pluripotent stem cells. Epigenetics Chromatin 2010 1.15
29 Coordinate regulation of DNA methyltransferase expression during oogenesis. BMC Dev Biol 2007 1.12
30 Loss of spermatogonia and wide-spread DNA methylation defects in newborn male mice deficient in DNMT3L. BMC Dev Biol 2007 0.97
31 Allele-specific demethylation at an imprinted mammalian promoter. Nucleic Acids Res 2007 0.96
32 Helicase homologues maintain cytosine methylation in plants and mammals. Bioessays 2002 0.96
33 Reactivation of a silenced H19 gene in human rhabdomyosarcoma by demethylation of DNA but not by histone hyperacetylation. Mol Cancer 2002 0.93
34 Decatenation checkpoint deficiency destabilizes the stem cell genome. Cell Cycle 2006 0.82
35 Genetics and epigenetics of hydatidiform moles. Nat Genet 2006 0.77
36 Combing over heritable gene silencing. Nat Struct Mol Biol 2006 0.75