PubRank

Daan J A Crommelin

Author PubWeight™ 66.29‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Identification of formaldehyde-induced modifications in proteins: reactions with model peptides. J Biol Chem 2003 2.60
2 Structure-immunogenicity relationships of therapeutic proteins. Pharm Res 2004 2.39
3 Overlooking subvisible particles in therapeutic protein products: gaps that may compromise product quality. J Pharm Sci 2009 2.36
4 Artificial viruses: a nanotechnological approach to gene delivery. Nat Rev Drug Discov 2006 1.52
5 Identification of formaldehyde-induced modifications in proteins: reactions with insulin. Bioconjug Chem 2006 1.37
6 Micelle-associated protein in epoetin formulations: aA risk factor for immunogenicity? Pharm Res 2003 1.34
7 Antibody response to aggregated human interferon alpha2b in wild-type and transgenic immune tolerant mice depends on type and level of aggregation. J Pharm Sci 2006 1.32
8 Structural characterization and immunogenicity in wild-type and immune tolerant mice of degraded recombinant human interferon alpha2b. Pharm Res 2005 1.32
9 The therapeutic equivalence of complex drugs. Regul Toxicol Pharmacol 2010 1.20
10 How to screen non-viral gene delivery systems in vitro? J Control Release 2011 1.17
11 Potential inaccurate quantitation and sizing of protein aggregates by size exclusion chromatography: essential need to use orthogonal methods to assure the quality of therapeutic protein products. J Pharm Sci 2010 1.16
12 Endosomal escape of polymeric gene delivery complexes is not always enhanced by polymers buffering at low pH. Biomacromolecules 2004 1.09
13 The nuclear pore complex: the gateway to successful nonviral gene delivery. Pharm Res 2006 1.07
14 Self-assembly of recombinant amphiphilic oligopeptides into vesicles. Biomacromolecules 2007 1.02
15 Polymer side-chain degradation as a tool to control the destabilization of polyplexes. Pharm Res 2004 0.98
16 Poly(3-guanidinopropyl methacrylate): a novel cationic polymer for gene delivery. Bioconjug Chem 2004 0.97
17 N-trimethyl chitosan (TMC) nanoparticles loaded with influenza subunit antigen for intranasal vaccination: biological properties and immunogenicity in a mouse model. Vaccine 2006 0.94
18 A novel family of L-amino acid-based biodegradable polymer-lipid conjugates for the development of long-circulating liposomes with effective drug-targeting capacity. Bioconjug Chem 2003 0.94
19 Controlled release of octreotide and assessment of peptide acylation from poly(D,L-lactide-co-hydroxymethyl glycolide) compared to PLGA microspheres. Pharm Res 2011 0.94
20 Protein instability and immunogenicity: roadblocks to clinical application of injectable protein delivery systems for sustained release. J Pharm Sci 2011 0.94
21 Liposomes and ISCOMs. Vaccine 2003 0.92
22 Assuring quality and performance of sustained and controlled release parenterals: EUFEPS workshop report. AAPS PharmSci 2004 0.91
23 Stabilization of peptide vesicles by introducing inter-peptide disulfide bonds. Pharm Res 2009 0.90
24 Physicochemical and immunochemical techniques predict the quality of diphtheria toxoid vaccines. Vaccine 2003 0.90
25 Restored functional immunogenicity of purified meningococcal PorA by incorporation into liposomes. Vaccine 2003 0.89
26 Validation of the transferrin receptor for drug targeting to brain capillary endothelial cells in vitro. J Drug Target 2004 0.89
27 Superoxide dismutase entrapped in long-circulating liposomes: formulation design and therapeutic activity in rat adjuvant arthritis. Biochim Biophys Acta 2002 0.87
28 Distinct effects of sucrose and trehalose on protein stability during supercritical fluid drying and freeze-drying. Eur J Pharm Sci 2005 0.87
29 Scientific considerations for complex drugs in light of established and emerging regulatory guidance. Ann N Y Acad Sci 2012 0.87
30 Diphtheria toxoid-containing microparticulate powder formulations for pulmonary vaccination: preparation, characterization and evaluation in guinea pigs. Vaccine 2007 0.86
31 Reaction to the paper: interaction of polysorbate 80 with erythropoietin: a case study in protein-surfactant interactions. Pharm Res 2006 0.85
32 Stabilization of proteins in dry powder formulations using supercritical fluid technology. Pharm Res 2004 0.85
33 Stability of mono- and trivalent meningococcal outer membrane vesicle vaccines. Vaccine 2004 0.85
34 Public-private partnerships in translational medicine: concepts and practical examples. J Control Release 2012 0.84
35 Cationic polymethacrylates with covalently linked membrane destabilizing peptides as gene delivery vectors. J Control Release 2005 0.84
36 Poly(ethylene glycol)--oligolactates with monodisperse hydrophobic blocks: preparation, characterization, and behavior in water. Langmuir 2005 0.83
37 Plasmid engineering for controlled and sustained gene expression for nonviral gene therapy. Pharm Res 2006 0.83
38 Assuring quality and performance of sustained and controlled released parenterals. Eur J Pharm Sci 2004 0.83
39 Well-defined and potent liposomal meningococcal B vaccines adjuvated with LPS derivatives. Vaccine 2005 0.83
40 Effect of the spraying conditions and nozzle design on the shape and size distribution of particles obtained with supercritical fluid drying. Eur J Pharm Biopharm 2008 0.83
41 The effect of core composition in biodegradable oligomeric micelles as taxane formulations. Eur J Pharm Biopharm 2007 0.82
42 Characterization and modulation of the transferrin receptor on brain capillary endothelial cells. Pharm Res 2004 0.82
43 Targeting liposomes with protein drugs to the blood-brain barrier in vitro. Eur J Pharm Sci 2005 0.82
44 Efficacy of pulmonary insulin delivery in diabetic rats: use of a model-based approach in the evaluation of insulin powder formulations. J Control Release 2008 0.81
45 Antigen-expressing immunostimulatory liposomes as a genetically programmable synthetic vaccine. Syst Synth Biol 2010 0.81
46 Quality control of routine, experimental and real-time aged diphtheria toxoids by in vitro analytical techniques. Vaccine 2007 0.81
47 Optimization and quantification of protein synthesis inside liposomes. J Liposome Res 2010 0.80
48 Modeling the release of proteins from degrading crosslinked dextran microspheres using kinetic Monte Carlo simulations. J Control Release 2006 0.80
49 PEG shielded polymeric double-layered micelles for gene delivery. J Control Release 2005 0.80
50 DNA nuclear targeting sequences for non-viral gene delivery. Pharm Res 2011 0.80
51 Cationic polymers that enhance the performance of HbsAg DNA in vivo. Vaccine 2004 0.80
52 How to regulate nonbiological complex drugs (NBCD) and their follow-on versions: points to consider. AAPS J 2013 0.80
53 Hydrophilic polyester microspheres: effect of molecular weight and copolymer composition on release of BSA. Pharm Res 2010 0.79
54 Measuring the value of public-private partnerships in the pharmaceutical sciences. Nat Rev Drug Discov 2012 0.79
55 Targeted liposomes for delivery of protein-based drugs into the cytoplasm of tumor cells. J Liposome Res 2003 0.79
56 Liposomal meningococcal B vaccination: role of dendritic cell targeting in the development of a protective immune response. Infect Immun 2003 0.78
57 Junk DNA enhances pEI-based non-viral gene delivery. Int J Pharm 2009 0.78
58 Virosome and ISCOM vaccines against Newcastle disease: preparation, characterization and immunogenicity. Eur J Pharm Sci 2004 0.77
59 Coupling of metal containing homing devices to liposomes via a maleimide linker: use of TCEP to stabilize thiol-groups without scavenging metals. J Drug Target 2004 0.77
60 Preparation and physicochemical characterization of supercritically dried insulin-loaded microparticles for pulmonary delivery. Eur J Pharm Biopharm 2007 0.77
61 In vitro degradation behavior of microspheres based on cross-linked dextran. Biomacromolecules 2006 0.77
62 Multi-antigen immunization using IgG binding domain ZZ as carrier. Vaccine 2005 0.77
63 Peptide nanocarriers for intracellular delivery of photosensitizers. J Control Release 2009 0.77
64 A mechanistic study on the chemical and enzymatic degradation of PEG-Oligo(epsilon-caprolactone) micelles. J Pharm Sci 2008 0.77
65 Semisolid, self-catalyzed poly(ortho ester)s as controlled-release systems: protein release and protein stability issues. J Pharm Sci 2002 0.77
66 Impact of the pharmaceutical sciences on health care: a reflection over the past 50 years. J Pharm Sci 2012 0.77
67 Conformation and intermolecular interactions of SA2 peptides self-assembled into vesicles. J Phys Chem B 2010 0.76
68 Equivocal role of micelles in Eprex adverse events. Nat Biotechnol 2003 0.75
69 Stable sugar-based protein formulations by supercritical fluid drying. Int J Pharm 2007 0.75
70 The pharmaceutical sciences in 2020: report of a conference organized by the board of pharmaceutical sciences of the International Pharmaceutical Federation (FIP). Pharm Res 2010 0.75
71 Delivery of biologicals: the wish list is long... Expert Opin Drug Deliv 2004 0.75
72 Supercritical fluid drying of carbohydrates: selection of suitable excipients and process conditions. Eur J Pharm Biopharm 2007 0.75
73 Assuring quality and performance of sustained and controlled release parenterals: EUFEPS workshop report. AAPS J 2004 0.75
74 Reversible aggregation of lysozyme in a biodegradable amphiphilic multiblock copolymer. Eur J Pharm Biopharm 2002 0.75
75 The pharmaceutical sciences in 2020--report of a conference organized by the Board of Pharmaceutical Sciences of the International Pharmaceutical Federation (FIP). Eur J Pharm Sci 2009 0.75
76 Stabilization of IgG by supercritical fluid drying: optimization of formulation and process parameters. Eur J Pharm Biopharm 2007 0.75
77 EUFEPS report. Contribution of academic research to discovery and development of medicines: current status and future opportunities. Eur J Pharm Sci 2005 0.75
78 Immunogenicity of meningococcal PorA formulations encapsulated in biodegradable microspheres. Eur J Pharm Sci 2004 0.75