Xenon: from stranger to guardian.

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Published in Curr Opin Anaesthesiol on August 01, 2005

Authors

Robert D Sanders1, Mervyn Maze

Author Affiliations

1: Department of Anaesthetics and Intensive Care, Faculty of Medicine, Imperial College, London, UK.

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(truncated to the top 100)

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Competitive inhibition at the glycine site of the N-methyl-D-aspartate receptor by the anesthetics xenon and isoflurane: evidence from molecular modeling and electrophysiology. Anesthesiology (2007) 1.97

Dexmedetomidine for prevention of postoperative delirium in older adults undergoing oesophagectomy with total intravenous anaesthesia: A double-blind, randomised clinical trial. Eur J Anaesthesiol (2021) 1.92

The neuroprotective effect of xenon administration during transient middle cerebral artery occlusion in mice. Anesthesiology (2003) 1.83

The neuroprotective effects of xenon and helium in an in vitro model of traumatic brain injury. Crit Care Med (2008) 1.81

Xenon mitigates isoflurane-induced neuronal apoptosis in the developing rodent brain. Anesthesiology (2007) 1.80

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Xenon preconditioning protects against renal ischemic-reperfusion injury via HIF-1alpha activation. J Am Soc Nephrol (2009) 1.43

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Comparative analgesic and mental effects of increasing plasma concentrations of dexmedetomidine and alfentanil in humans. Anesthesiology (2004) 1.20

Neuronal preconditioning by inhalational anesthetics: evidence for the role of plasmalemmal adenosine triphosphate-sensitive potassium channels. Anesthesiology (2009) 1.18

alpha2-Adrenoceptor agonists: shedding light on neuroprotection? Br Med Bull (2005) 1.17

Anticipating and managing postoperative delirium and cognitive decline in adults. BMJ (2011) 1.16

Xenon augmented hypothermia reduces early lactate/N-acetylaspartate and cell death in perinatal asphyxia. Ann Neurol (2011) 1.13

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General anesthetics induce apoptotic neurodegeneration in the neonatal rat spinal cord. Anesth Analg (2008) 1.09

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Xenon pretreatment attenuates anesthetic-induced apoptosis in the developing brain in comparison with nitrous oxide and hypoxia. Anesthesiology (2010) 1.05

Molecular mechanisms transducing the anesthetic, analgesic, and organ-protective actions of xenon. Anesthesiology (2006) 1.05

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Dysfunction of inflammation-resolving pathways is associated with exaggerated postoperative cognitive decline in a rat model of the metabolic syndrome. Mol Med (2013) 1.03

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Xenon and sevoflurane protect against brain injury in a neonatal asphyxia model. Anesthesiology (2008) 0.95

Neurobiology of nitrous oxide-induced antinociceptive effects. Mol Neurobiol (2002) 0.95

Determinants of the anesthetic sensitivity of two-pore domain acid-sensitive potassium channels: molecular cloning of an anesthetic-activated potassium channel from Lymnaea stagnalis. J Biol Chem (2007) 0.95

Alpha2-adrenoceptor agonists. Curr Opin Investig Drugs (2007) 0.94

Bone fracture exacerbates murine ischemic cerebral injury. Anesthesiology (2013) 0.94

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Alpha-7 nicotinic acetylcholine receptor agonist treatment reduces neuroinflammation, oxidative stress, and brain injury in mice with ischemic stroke and bone fracture. J Neurochem (2014) 0.92

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Corticotropin-releasing factor mediates the antinociceptive action of nitrous oxide in rats. Anesthesiology (2003) 0.81

Xenon up-regulates several genes that are not up-regulated by nitrous oxide. J Neurosurg Anesthesiol (2008) 0.81

Combination of xenon and isoflurane produces a synergistic protective effect against oxygen-glucose deprivation injury in a neuronal-glial co-culture model. Anesthesiology (2003) 0.80

The differential effects of nitrous oxide and xenon on extracellular dopamine levels in the rat nucleus accumbens: a microdialysis study. Anesth Analg (2006) 0.80

Noble gas xenon is a novel adenosine triphosphate-sensitive potassium channel opener. Anesthesiology (2010) 0.79

Xenon and the inflammatory response to cardiopulmonary bypass in the rat. J Cardiothorac Vasc Anesth (2005) 0.79

Evidence for the involvement of spinal cord alpha1 adrenoceptors in nitrous oxide-induced antinociceptive effects in Fischer rats. Anesthesiology (2002) 0.79

Brain stem opioidergic and GABAergic neurons mediate the antinociceptive effect of nitrous oxide in Fischer rats. Anesthesiology (2003) 0.79

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GABAergic interneurons at supraspinal and spinal levels differentially modulate the antinociceptive effect of nitrous oxide in Fischer rats. Anesthesiology (2003) 0.78

The Hip Fracture Surgery in Elderly Patients (HIPELD) study: protocol for a randomized, multicenter controlled trial evaluating the effect of xenon on postoperative delirium in older patients undergoing hip fracture surgery. Trials (2012) 0.78

Correction: Activation of α-7 Nicotinic Acetylcholine Receptor Reduces Ischemic Stroke Injury through Reduction of Pro-Inflammatory Macrophages and Oxidative Stress. PLoS One (2016) 0.77

Rested and refreshed after anesthesia? Overlapping neurobiologic mechanisms of sleep and anesthesia. Anesthesiology (2004) 0.77

Xenon exerts age-independent antinociception in Fischer rats. Anesthesiology (2004) 0.77