Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial.

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Published in Crit Care on March 16, 2010

Authors

Pratik P Pandharipande1, Robert D Sanders, Timothy D Girard, Stuart McGrane, Jennifer L Thompson, Ayumi K Shintani, Daniel L Herr, Mervyn Maze, E Wesley Ely, MENDS investigators

Author Affiliations

1: Anesthesiology Service, VA TN Valley Health Care System, Nashville, TN 37212-2637, USA. pratik.pandharipande@Vanderbilt.Edu

Associated clinical trials:

MENDS Study: Trial in Ventilated ICU Patients Comparing an Alpha2 Agonist Versus a Gamma Aminobutyric Acid (GABA)-Agonist to Determine Delirium Rates, Efficacy of Sedation, Analgesia and Discharge Cognitive Status | NCT00095251

Enteral Versus Intravenous Sedation in Critically Ill High-risk ICU Patients | NCT01360346

Pain, Agitation and Delirium (PAD) Protocol in the Duke CICU | NCT02903407

Study of Sedative Medications in Patients With Severe Infection and Respiratory Failure (PRO-DEFENSE) | NCT02203019

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