Published in Neurochem Int on March 23, 2006
An overview of animal models for investigating the pathogenesis and therapeutic strategies in acute hepatic failure. World J Gastroenterol (2009) 1.54
The liver-brain axis in liver failure: neuroinflammation and encephalopathy. Nat Rev Gastroenterol Hepatol (2013) 1.05
Matrix metalloproteinase-9 contributes to parenchymal hemorrhage and necrosis in the remnant liver after extended hepatectomy in mice. World J Gastroenterol (2012) 0.93
Inflammatory cascades driven by tumor necrosis factor-alpha play a major role in the progression of acute liver failure and its neurological complications. PLoS One (2012) 0.91
Real-time analysis of microglial activation and motility in hepatic and hyperammonemic encephalopathy. Neuroscience (2012) 0.89
Experimental models of hepatotoxicity related to acute liver failure. Toxicol Appl Pharmacol (2015) 0.88
Altered expression of zonula occludens-2 precedes increased blood-brain barrier permeability in a murine model of fulminant hepatic failure. J Invest Surg (2008) 0.88
Occludin is regulated by epidermal growth factor receptor activation in brain endothelial cells and brains of mice with acute liver failure. Hepatology (2011) 0.86
Scopolamine treatment and muscarinic receptor subtype-3 gene ablation augment azoxymethane-induced murine liver injury. J Pharmacol Exp Ther (2010) 0.84
Fulminant liver failure model with hepatic encephalopathy in the mouse. Ann Gastroenterol (2011) 0.80
Effects of modulating M3 muscarinic receptor activity on azoxymethane-induced liver injury in mice. Biochem Pharmacol (2013) 0.79
Bile Acid Signaling Is Involved in the Neurological Decline in a Murine Model of Acute Liver Failure. Am J Pathol (2015) 0.78
A Src family kinase inhibitor improves survival in experimental acute liver failure associated with elevated cerebral and circulating vascular endothelial growth factor levels. Liver Int (2011) 0.77
Matrix metalloproteinase-9 in the initial injury after hepatectomy in mice. World J Gastroenterol (2013) 0.77
Murine model to study brain, behavior and immunity during hepatic encephalopathy. World J Hepatol (2014) 0.77
A Macaca mulatta model of fulminant hepatic failure. World J Gastroenterol (2012) 0.77
Subtle BBB alterations in brain edema associated with acute liver failure. Neurochem Int (2010) 0.76
MRI/DTI of the Brain Stem Reveals Reversible and Irreversible Disruption of the Baroreflex Neural Circuits: Clinical Implications. Theranostics (2016) 0.75
Carnosine Reduces Oxidative Stress and Reverses Attenuation of Righting and Postural Reflexes in Rats with Thioacetamide-Induced Liver Failure. Neurochem Res (2016) 0.75
Neurobiology of ammonia. Prog Neurobiol (2002) 1.84
Effects of hypothermia on brain glucose metabolism in acute liver failure: a H/C-nuclear magnetic resonance study. Gastroenterology (2003) 1.60
Alterations in expression of genes coding for proteins of the neurovascular unit in ischemic liver failure. Neurochem Int (2009) 1.55
Hepatic hemodynamics in 24 patients with nodular regenerative hyperplasia and symptomatic portal hypertension. J Gastroenterol Hepatol (2012) 1.52
Effect of albumin dialysis on intracranial pressure increase in pigs with acute liver failure: a randomized study. Crit Care Med (2006) 1.50
Perispinal etanercept for post-stroke neurological and cognitive dysfunction: scientific rationale and current evidence. CNS Drugs (2014) 1.49
Increased brain serotonin turnover correlates with the degree of shunting and hyperammonemia in rats following variable portal vein stenosis. J Hepatol (2004) 1.44
Update of cell damage mechanisms in thiamine deficiency: focus on oxidative stress, excitotoxicity and inflammation. Alcohol Alcohol (2009) 1.11
The contribution of structured activity and deliberate play to the development of expert perceptual and decision-making skill. J Sport Exerc Psychol (2008) 1.09
Cerebral inflammation contributes to encephalopathy and brain edema in acute liver failure: protective effect of minocycline. J Neurochem (2009) 1.08
Ammonia induces MK-801-sensitive nitration and phosphorylation of protein tyrosine residues in rat astrocytes. FASEB J (2002) 1.07
Learning from the experts: practice activities of expert decision makers in sport. Res Q Exerc Sport (2003) 1.06
Direct evidence for central proinflammatory mechanisms in rats with experimental acute liver failure: protective effect of hypothermia. J Cereb Blood Flow Metab (2009) 1.06
Mild hypothermia attenuates liver injury and improves survival in mice with acetaminophen toxicity. Gastroenterology (2006) 1.04
Management of hepatic granulomatous tuberculosis complicating intravesical BCG for superficial bladder cancer. Can Urol Assoc J (2007) 1.02
IL-1 or TNF receptor gene deletion delays onset of encephalopathy and attenuates brain edema in experimental acute liver failure. Neurochem Int (2009) 1.01
N-acetylcysteine attenuates cerebral complications of non-acetaminophen-induced acute liver failure in mice: antioxidant and anti-inflammatory mechanisms. Metab Brain Dis (2010) 1.00
Direct molecular and spectroscopic evidence for increased ammonia removal capacity of skeletal muscle in acute liver failure. J Hepatol (2006) 0.97
Pathogenesis of hepatic encephalopathy: new insights from neuroimaging and molecular studies. J Hepatol (2003) 0.93
Selective increase of brain lactate synthesis in experimental acute liver failure: results of a [H-C] nuclear magnetic resonance study. Hepatology (2003) 0.93
Role of mitochondrial dysfunction and oxidative stress in the pathogenesis of selective neuronal loss in Wernicke's encephalopathy. Mol Neurobiol (2005) 0.92
Mitochondrial dysfunction in acute hyperammonemia. Neurochem Int (2002) 0.92
The neurosteroid system: implication in the pathophysiology of hepatic encephalopathy. Neurochem Int (2007) 0.91
Pathogenesis of hepatic encephalopathy and brain edema in acute liver failure: role of glutamine redefined. Neurochem Int (2012) 0.91
Inflammatory cascades driven by tumor necrosis factor-alpha play a major role in the progression of acute liver failure and its neurological complications. PLoS One (2012) 0.91
Patterns of early involvement in expert and nonexpert masters triathletes. Res Q Exerc Sport (2006) 0.91
Acute liver failure: a critical appraisal of available animal models. Metab Brain Dis (2005) 0.90
Increased brain endothelial nitric oxide synthase expression in thiamine deficiency: relationship to selective vulnerability. Neurochem Int (2004) 0.87
Liver-brain proinflammatory signalling in acute liver failure: role in the pathogenesis of hepatic encephalopathy and brain edema. Metab Brain Dis (2012) 0.87
A proposed theoretical model to explain relative age effects in sport. Eur J Sport Sci (2013) 0.87
Loss of expression of glial fibrillary acidic protein in acute hyperammonemia. Neurochem Int (2002) 0.87
Mild hypothermia in the prevention of brain edema in acute liver failure: mechanisms and clinical prospects. Metab Brain Dis (2002) 0.86
Ammonia and proinflammatory cytokines modify expression of genes coding for astrocytic proteins implicated in brain edema in acute liver failure. Metab Brain Dis (2010) 0.86
Hypertrophy of the non-embolized liver after chemotherapy. HPB (Oxford) (2009) 0.86
Keeping cool in acute liver failure: rationale for the use of mild hypothermia. J Hepatol (2005) 0.86
Examination of birthplace and birthdate in World Junior ice hockey players. J Sports Sci (2011) 0.86
Altered expression of tight junction proteins and matrix metalloproteinases in thiamine-deficient mouse brain. Neurochem Int (2009) 0.86
The brain glutamate system in liver failure. J Neurochem (2006) 0.85
Minocycline attenuates oxidative/nitrosative stress and cerebral complications of acute liver failure in rats. Neurochem Int (2009) 0.85
Dehydroascorbic acid normalizes several markers of oxidative stress and inflammation in acute hyperglycemic focal cerebral ischemia in the rat. Neurochem Int (2005) 0.85
Region selective alterations of soluble guanylate cyclase content and modulation in brain of cirrhotic patients. Hepatology (2002) 0.85
Manganese distribution in the brain and neurobehavioral changes following inhalation exposure of rats to three chemical forms of manganese. Neurotoxicology (2004) 0.84
Normal coupling of brain benzodiazepine and neurosteroid modulatory sites on the GABA-A receptor complex in human hepatic encephalopathy. Neurochem Int (2003) 0.84
Increased levels of pregnenolone and its neuroactive metabolite allopregnanolone in autopsied brain tissue from cirrhotic patients who died in hepatic coma. Neurochem Int (2006) 0.84
Increased Na, K-ATPase alpha2 isoform gene expression by ammonia in astrocytes and in brain in vivo. Neurochem Int (2010) 0.83
Selective alterations of brain osmolytes in acute liver failure: protective effect of mild hypothermia. Brain Res (2004) 0.83
Lipopolysaccharide precipitates hepatic encephalopathy and increases blood-brain barrier permeability in mice with acute liver failure. Liver Int (2013) 0.83
Antioxidant and anti-inflammatory effects of mild hypothermia in the attenuation of liver injury due to azoxymethane toxicity in the mouse. Metab Brain Dis (2010) 0.83
Increased brain concentrations of a neuroinhibitory steroid in human hepatic encephalopathy. Ann Neurol (2005) 0.83
Region-selective alterations of glucose oxidation and amino acid synthesis in the thiamine-deficient rat brain: a re-evaluation using 1H/13C nuclear magnetic resonance spectroscopy. J Neurochem (2008) 0.83
Selective increase of neuronal cyclooxygenase-2 (COX-2) expression in vulnerable brain regions of rats with experimental Wernicke's encephalopathy: effect of nimesulide. Metab Brain Dis (2008) 0.83
Pathophysiology of hepatic encephalopathy: a new look at GABA from the molecular standpoint. Metab Brain Dis (2004) 0.82
Selectively increased expression of the astrocytic/endothelial glucose transporter protein GLUT1 in acute liver failure. Glia (2006) 0.82
Induction of astrocytic cyclooxygenase-2 in epileptic patients with hippocampal sclerosis. Neurochem Int (2003) 0.82
Up-regulation of caveolin-1 and blood-brain barrier breakdown are attenuated by N-acetylcysteine in thiamine deficiency. Neurochem Int (2010) 0.81
Mechanisms of brain edema in acute liver failure and impact of novel therapeutic interventions. Neurol Res (2007) 0.81
Reduced brain levels of DHEAS in hepatic coma patients: significance for increased GABAergic tone in hepatic encephalopathy. Neurochem Int (2012) 0.81
Expression of superoxide dismutase in hyperglycemic focal cerebral ischemia in the rat. Neurochem Int (2004) 0.81
The "peripheral-type" benzodiazepine (omega 3) receptor in hyperammonemic disorders. Neurochem Int (2002) 0.80
The biosynthesis of ascorbate protects isolated rat hepatocytes from cumene hydroperoxide-mediated oxidative stress. Free Radic Biol Med (2005) 0.80
Assessment of bioaccumulation, neuropathology, and neurobehavior following subchronic (90 days) inhalation in Sprague-Dawley rats exposed to manganese phosphate. Toxicol Appl Pharmacol (2002) 0.80
An interaction between benzodiazepines and neuroactive steroids at GABA A receptors in cultured hippocampal neurons. Neurochem Int (2006) 0.80
Evidence for oxidative/nitrosative stress in the pathogenesis of hepatic encephalopathy. Metab Brain Dis (2010) 0.80
Role of nutrition in the management of hepatic encephalopathy in end-stage liver failure. J Nutr Metab (2010) 0.80
Increased brain concentrations of endogenous (non-benzodiazepine) GABA-A receptor ligands in human hepatic encephalopathy. Metab Brain Dis (2004) 0.79
Primary cultures of rat astrocytes respond to thiamine deficiency-induced swelling by downregulating aquaporin-4 levels. Neurosci Lett (2004) 0.79
The neurosteroid system: an emerging therapeutic target for hepatic encephalopathy. Metab Brain Dis (2007) 0.79
Mild hypothermia for the treatment of acute liver failure--what are we waiting for? Nat Clin Pract Gastroenterol Hepatol (2007) 0.79
Expression of astrocytic genes coding for proteins implicated in neural excitation and brain edema is altered after acute liver failure. J Neurochem (2013) 0.79
Mild hypothermia prevents brain edema and attenuates up-regulation of the astrocytic benzodiazepine receptor in experimental acute liver failure. J Hepatol (2005) 0.79
Impaired oxidation of branched-chain amino acids in the medial thalamus of thiamine-deficient rats. Metab Brain Dis (2008) 0.78
Role of endogenous benzodiazepine ligands and their GABA-A--associated receptors in hepatic encephalopathy. Metab Brain Dis (2005) 0.78
Lack of assessment of body temperature in mice with acetaminophen toxicity. Hepatology (2006) 0.78
Selective alterations of brain dopamine D(2) receptor binding in cirrhotic patients: results of a (11)C-N-methylspiperone PET study. Metab Brain Dis (2008) 0.78
Hypothermia attenuates oxidative/nitrosative stress, encephalopathy and brain edema in acute (ischemic) liver failure. Neurochem Int (2009) 0.78
Editorial: rifaximin and minimal hepatic encephalopathy. Am J Gastroenterol (2011) 0.78
[Nephrogenic systemic fibrosis: more hard times for renal failure patients]. Nephrol Ther (2007) 0.78
Cell-selective effects of ammonia on glutamate transporter and receptor function in the mammalian brain. Neurochem Int (2003) 0.78
eNOS gene deletion restores blood-brain barrier integrity and attenuates neurodegeneration in the thiamine-deficient mouse brain. J Neurochem (2009) 0.77
Liver: risk of falls in cirrhosis predicted by psychometric testing. Nat Rev Gastroenterol Hepatol (2012) 0.76
Reduced plasma dehydroepiandrosterone sulfate levels are significantly correlated with fatigue severity in patients with primary biliary cirrhosis. Neurochem Int (2007) 0.76
Selective loss of expression of glutamate GluR2/R3 receptor subunits in cerebellar tissue from a patient with olivopontocerebellar atrophy. Metab Brain Dis (2002) 0.76
Reduced expression of astrocytic glycine transporter (Glyt-1) in acute liver failure. Metab Brain Dis (2002) 0.76
From early to adult sport success: analysing athletes' progression in national squads. Eur J Sport Sci (2012) 0.76
Brain lactate synthesis in thiamine deficiency: a re-evaluation using 1H-13C nuclear magnetic resonance spectroscopy. J Neurosci Res (2004) 0.76
Effects of ammonia on high affinity glutamate uptake and glutamate transporter EAAT3 expression in cultured rat cerebellar granule cells. Neurochem Int (2003) 0.76
Glucose loading precipitates focal lactic acidosis in the vulnerable medial thalamus of thiamine-deficient rats. Metab Brain Dis (2007) 0.75
Birthplace effects on the development of female athletic talent. J Sci Med Sport (2007) 0.75
Bullying Victimization and Perpetration Among Adolescent Sport Teammates. Pediatr Exerc Sci (2015) 0.75
Interferon beta-induced panniculitis mimicking acute appendicitis. Arch Dermatol (2009) 0.75
Differential effects of ammonia on the benzodiazepine modulatory site on the GABA-A receptor complex of human brain. Neurochem Int (2005) 0.75