PubRank

Y Peng Loh

Author PubWeight™ 54.87‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Sorting and activity-dependent secretion of BDNF require interaction of a specific motif with the sorting receptor carboxypeptidase e. Neuron 2005 1.69
2 Reengineered salivary glands are stable endogenous bioreactors for systemic gene therapeutics. Proc Natl Acad Sci U S A 2004 1.64
3 Dense-core secretory granule biogenesis. Physiology (Bethesda) 2006 1.62
4 The obesity susceptibility gene Cpe links FoxO1 signaling in hypothalamic pro-opiomelanocortin neurons with regulation of food intake. Nat Med 2009 1.55
5 The extended granin family: structure, function, and biomedical implications. Endocr Rev 2011 1.43
6 The carboxypeptidase E knockout mouse exhibits endocrinological and behavioral deficits. Endocrinology 2004 1.33
7 New roles of carboxypeptidase E in endocrine and neural function and cancer. Endocr Rev 2012 1.23
8 A bi-directional carboxypeptidase E-driven transport mechanism controls BDNF vesicle homeostasis in hippocampal neurons. Mol Cell Neurosci 2008 1.15
9 Carboxypeptidase E, a prohormone sorting receptor, is anchored to secretory granules via a C-terminal transmembrane insertion. Biochemistry 2002 1.13
10 Carboxypeptidase E cytoplasmic tail-driven vesicle transport is key for activity-dependent secretion of peptide hormones. Mol Endocrinol 2008 1.10
11 Chromogranin A deficiency in transgenic mice leads to aberrant chromaffin granule biogenesis. J Neurosci 2005 1.06
12 Absence of carboxypeptidase E leads to adult hippocampal neuronal degeneration and memory deficits. Hippocampus 2008 1.05
13 How peptide hormone vesicles are transported to the secretion site for exocytosis. Mol Endocrinol 2008 1.04
14 Abnormal sterols in cholesterol-deficiency diseases cause secretory granule malformation and decreased membrane curvature. J Cell Sci 2006 1.04
15 An N-terminal truncated carboxypeptidase E splice isoform induces tumor growth and is a biomarker for predicting future metastasis in human cancers. J Clin Invest 2011 1.02
16 Fluorescent cargo proteins in pancreatic beta-cells: design determines secretion kinetics at exocytosis. Biophys J 2004 1.02
17 Carboxypeptidase E/NFα1: a new neurotrophic factor against oxidative stress-induced apoptotic cell death mediated by ERK and PI3-K/AKT pathways. PLoS One 2013 1.02
18 Carboxypeptidase E: elevated expression correlated with tumor growth and metastasis in pheochromocytomas and other cancers. Cell Mol Neurobiol 2010 1.02
19 Recycling of Raft-associated prohormone sorting receptor carboxypeptidase E requires interaction with ARF6. Mol Biol Cell 2003 1.01
20 Carboxypeptidase E is required for normal synaptic transmission from photoreceptors to the inner retina. J Neurochem 2005 1.00
21 Neuroprotective protein and carboxypeptidase E. J Mol Neurosci 2009 0.99
22 Protease nexin-1 promotes secretory granule biogenesis by preventing granule protein degradation. Mol Biol Cell 2005 0.98
23 The molecular profiles of neural stem cell niche in the adult subventricular zone. PLoS One 2012 0.97
24 A new chromogranin A-dependent angiogenic switch activated by thrombin. Blood 2012 0.96
25 Partial redirection of transgenic human growth hormone secretion from rat salivary glands. Hum Gene Ther 2005 0.96
26 Obese carboxypeptidase E knockout mice exhibit multiple defects in peptide hormone processing contributing to low bone mineral density. Am J Physiol Endocrinol Metab 2010 0.94
27 Aquaporin 1 is important for maintaining secretory granule biogenesis in endocrine cells. Mol Endocrinol 2008 0.93
28 The prohormone processing enzyme PC3 is a lipid raft-associated transmembrane protein. Biochemistry 2003 0.92
29 The transmembrane domain of the prohormone convertase PC3: a key motif for targeting to the regulated secretory pathway. Mol Cell Endocrinol 2006 0.91
30 Biogenesis and transport of secretory granules to release site in neuroendocrine cells. J Mol Neurosci 2008 0.91
31 Systemic delivery of bioactive glucagon-like peptide 1 after adenoviral-mediated gene transfer in the murine salivary gland. Endocrinology 2010 0.90
32 Sorting behavior of a transgenic erythropoietin-growth hormone fusion protein in murine salivary glands. Hum Gene Ther 2008 0.89
33 The C-terminus of prohormone convertase 2 is sufficient and necessary for Raft association and sorting to the regulated secretory pathway. Biochemistry 2004 0.89
34 Disruption of a receptor-mediated mechanism for intracellular sorting of proinsulin in familial hyperproinsulinemia. Mol Endocrinol 2003 0.89
35 Sorting of carboxypeptidase E to the regulated secretory pathway requires interaction of its transmembrane domain with lipid rafts. Biochem J 2003 0.89
36 Carboxypeptidase E (NF-α1): a new trophic factor in neuroprotection. Neurosci Bull 2014 0.87
37 Carboxypeptidase E knockout mice exhibit abnormal dendritic arborization and spine morphology in central nervous system neurons. J Neurosci Res 2010 0.86
38 Serpinin: a novel chromogranin A-derived, secreted peptide up-regulates protease nexin-1 expression and granule biogenesis in endocrine cells. Mol Endocrinol 2011 0.86
39 The Leu34Phe ProCART mutation leads to cocaine- and amphetamine-regulated transcript (CART) deficiency: a possible cause for obesity in humans. Endocrinology 2005 0.86
40 Large dense-core secretory granule biogenesis is under the control of chromogranin A in neuroendocrine cells. Ann N Y Acad Sci 2002 0.86
41 Nerve growth factor-dependent sorting of synaptotagmin IV protein to mature dense-core vesicles that undergo calcium-dependent exocytosis in PC12 cells. J Biol Chem 2002 0.85
42 A distinct trans-Golgi network subcompartment for sorting of synaptic and granule proteins in neurons and neuroendocrine cells. J Cell Sci 2011 0.85
43 Trafficking of mutant carboxypeptidase E to secretory granules in a beta-cell line derived from Cpe(fat)/Cpe(fat) mice. Endocrinology 2003 0.85
44 The novel chromogranin A-derived serpinin and pyroglutaminated serpinin peptides are positive cardiac β-adrenergic-like inotropes. FASEB J 2012 0.85
45 Chromogranin A: a surprising link between granule biogenesis and hypertension. J Clin Invest 2005 0.84
46 Sorting of growth hormone-erythropoietin fusion proteins in rat salivary glands. Biochem Biophys Res Commun 2008 0.84
47 Cellular mechanisms for the biogenesis and transport of synaptic and dense-core vesicles. Int Rev Cell Mol Biol 2012 0.83
48 Role of pGlu-serpinin, a novel chromogranin A-derived peptide in inhibition of cell death. J Mol Neurosci 2011 0.82
49 Chromogranin A: a new proposal for trafficking, processing and induction of granule biogenesis. Regul Pept 2009 0.81
50 Visualization of peptide secretory vesicles in living nerve cells. Methods Mol Biol 2011 0.80
51 Synthesis and characterization of the first potent inhibitor of yapsin 1. Implications for the study of yapsin-like enzymes. J Biol Chem 2002 0.79
52 γ-Adducin promotes process outgrowth and secretory protein exit from the Golgi apparatus. J Mol Neurosci 2012 0.79
53 Reprint of: Chromogranin A: a new proposal for trafficking, processing and induction of granule biogenesis. Regul Pept 2010 0.77
54 Carboxypeptidase E, an essential element of the regulated secretory pathway, is expressed and partially co-localized with chromogranin A in chicken thymus. Cell Tissue Res 2009 0.75
55 Yapsin 1 immunoreactivity in {alpha}-cells of human pancreatic islets: implications for the processing of human proglucagon by mammalian aspartic proteases. J Endocrinol 2011 0.75
56 Commentary: neurotransmitter secretion and cell signaling. J Mol Neurosci 2012 0.75
57 Commentary: ion channels, fusion pores and exocytosis. J Mol Neurosci 2012 0.75