Published in Physiology (Bethesda) on April 01, 2006
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Redirecting intracellular trafficking and the secretion pattern of FSH dramatically enhances ovarian function in mice. Proc Natl Acad Sci U S A (2014) 0.91
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Microtubule-binding protein doublecortin-like kinase 1 (DCLK1) guides kinesin-3-mediated cargo transport to dendrites. EMBO J (2016) 0.82
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Amyloid-like aggregation of provasopressin in diabetes insipidus and secretory granule sorting. BMC Biol (2017) 0.80
A directed RNAi screen based on larval growth arrest reveals new modifiers of C. elegans insulin signaling. PLoS One (2012) 0.80
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Chromogranin A as a crucial factor in the sorting of peptide hormones to secretory granules. Cell Mol Neurobiol (2010) 0.78
An aspartyl cathepsin, CTH3, is essential for proprotein processing during secretory granule maturation in Tetrahymena thermophila. Mol Biol Cell (2014) 0.78
Development of the endocrine pancreas and novel strategies for β-cell mass restoration and diabetes therapy. Braz J Med Biol Res (2015) 0.78
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Secretory trafficking signal encoded in the carboxyl-terminal region of the CGbeta-subunit. Mol Endocrinol (2009) 0.77
Paracrine role of GABA in adrenal chromaffin cells. Cell Mol Neurobiol (2010) 0.77
An efficient two-step subcellular fractionation method for the enrichment of insulin granules from INS-1 cells. Biophys Rep (2015) 0.76
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Saving the neck from scission. Commun Integr Biol (2013) 0.75
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The EARP Complex and Its Interactor EIPR-1 Are Required for Cargo Sorting to Dense-Core Vesicles. PLoS Genet (2016) 0.75
Regulation of Dense-Core Granule Replenishment by Autocrine BMP Signalling in Drosophila Secondary Cells. PLoS Genet (2016) 0.75
The Drosophila Accessory Gland as a Model for Prostate Cancer and Other Pathologies. Curr Top Dev Biol (2016) 0.75
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Sorting and activity-dependent secretion of BDNF require interaction of a specific motif with the sorting receptor carboxypeptidase e. Neuron (2005) 1.69
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The carboxypeptidase E knockout mouse exhibits endocrinological and behavioral deficits. Endocrinology (2004) 1.33
Multiple uses of basement membrane-like matrix (BME/Matrigel) in vitro and in vivo with cancer cells. Int J Cancer (2011) 1.29
New roles of carboxypeptidase E in endocrine and neural function and cancer. Endocr Rev (2012) 1.23
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Chromogranin A deficiency in transgenic mice leads to aberrant chromaffin granule biogenesis. J Neurosci (2005) 1.06
Absence of carboxypeptidase E leads to adult hippocampal neuronal degeneration and memory deficits. Hippocampus (2008) 1.05
How peptide hormone vesicles are transported to the secretion site for exocytosis. Mol Endocrinol (2008) 1.04
Abnormal sterols in cholesterol-deficiency diseases cause secretory granule malformation and decreased membrane curvature. J Cell Sci (2006) 1.04
Carboxypeptidase E/NFα1: a new neurotrophic factor against oxidative stress-induced apoptotic cell death mediated by ERK and PI3-K/AKT pathways. PLoS One (2013) 1.02
An N-terminal truncated carboxypeptidase E splice isoform induces tumor growth and is a biomarker for predicting future metastasis in human cancers. J Clin Invest (2011) 1.02
Fluorescent cargo proteins in pancreatic beta-cells: design determines secretion kinetics at exocytosis. Biophys J (2004) 1.02
Carboxypeptidase E: elevated expression correlated with tumor growth and metastasis in pheochromocytomas and other cancers. Cell Mol Neurobiol (2010) 1.02
Recycling of Raft-associated prohormone sorting receptor carboxypeptidase E requires interaction with ARF6. Mol Biol Cell (2003) 1.01
Carboxypeptidase E is required for normal synaptic transmission from photoreceptors to the inner retina. J Neurochem (2005) 1.00
Neuroprotective protein and carboxypeptidase E. J Mol Neurosci (2009) 0.99
Protease nexin-1 promotes secretory granule biogenesis by preventing granule protein degradation. Mol Biol Cell (2005) 0.98
The molecular profiles of neural stem cell niche in the adult subventricular zone. PLoS One (2012) 0.97
Partial redirection of transgenic human growth hormone secretion from rat salivary glands. Hum Gene Ther (2005) 0.96
A new chromogranin A-dependent angiogenic switch activated by thrombin. Blood (2012) 0.96
Obese carboxypeptidase E knockout mice exhibit multiple defects in peptide hormone processing contributing to low bone mineral density. Am J Physiol Endocrinol Metab (2010) 0.94
Aquaporin 1 is important for maintaining secretory granule biogenesis in endocrine cells. Mol Endocrinol (2008) 0.93
The prohormone processing enzyme PC3 is a lipid raft-associated transmembrane protein. Biochemistry (2003) 0.92
The transmembrane domain of the prohormone convertase PC3: a key motif for targeting to the regulated secretory pathway. Mol Cell Endocrinol (2006) 0.91
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Systemic delivery of bioactive glucagon-like peptide 1 after adenoviral-mediated gene transfer in the murine salivary gland. Endocrinology (2010) 0.90
The C-terminus of prohormone convertase 2 is sufficient and necessary for Raft association and sorting to the regulated secretory pathway. Biochemistry (2004) 0.89
Sorting of carboxypeptidase E to the regulated secretory pathway requires interaction of its transmembrane domain with lipid rafts. Biochem J (2003) 0.89
Disruption of a receptor-mediated mechanism for intracellular sorting of proinsulin in familial hyperproinsulinemia. Mol Endocrinol (2003) 0.89
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The Leu34Phe ProCART mutation leads to cocaine- and amphetamine-regulated transcript (CART) deficiency: a possible cause for obesity in humans. Endocrinology (2005) 0.86
Serpinin: a novel chromogranin A-derived, secreted peptide up-regulates protease nexin-1 expression and granule biogenesis in endocrine cells. Mol Endocrinol (2011) 0.86
Carboxypeptidase E knockout mice exhibit abnormal dendritic arborization and spine morphology in central nervous system neurons. J Neurosci Res (2010) 0.86
Large dense-core secretory granule biogenesis is under the control of chromogranin A in neuroendocrine cells. Ann N Y Acad Sci (2002) 0.86
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The novel chromogranin A-derived serpinin and pyroglutaminated serpinin peptides are positive cardiac β-adrenergic-like inotropes. FASEB J (2012) 0.85
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Sorting of growth hormone-erythropoietin fusion proteins in rat salivary glands. Biochem Biophys Res Commun (2008) 0.84
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Chromogranin A: a surprising link between granule biogenesis and hypertension. J Clin Invest (2005) 0.84
Cellular mechanisms for the biogenesis and transport of synaptic and dense-core vesicles. Int Rev Cell Mol Biol (2012) 0.83
Role of pGlu-serpinin, a novel chromogranin A-derived peptide in inhibition of cell death. J Mol Neurosci (2011) 0.82
Chromogranin A: a new proposal for trafficking, processing and induction of granule biogenesis. Regul Pept (2009) 0.81
Visualization of peptide secretory vesicles in living nerve cells. Methods Mol Biol (2011) 0.80
Synthesis and characterization of the first potent inhibitor of yapsin 1. Implications for the study of yapsin-like enzymes. J Biol Chem (2002) 0.79
γ-Adducin promotes process outgrowth and secretory protein exit from the Golgi apparatus. J Mol Neurosci (2012) 0.79
Astrocyte fatty acid binding protein-7 is a marker for neurogenic niches in the rat hippocampus. Hippocampus (2013) 0.79
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Yapsin 1 immunoreactivity in {alpha}-cells of human pancreatic islets: implications for the processing of human proglucagon by mammalian aspartic proteases. J Endocrinol (2011) 0.75
Carboxypeptidase E, an essential element of the regulated secretory pathway, is expressed and partially co-localized with chromogranin A in chicken thymus. Cell Tissue Res (2009) 0.75
Commentary: ion channels, fusion pores and exocytosis. J Mol Neurosci (2012) 0.75
Commentary: neurotransmitter secretion and cell signaling. J Mol Neurosci (2012) 0.75