Published in Proc Natl Acad Sci U S A on August 01, 1974
Elastic area compressibility modulus of red cell membrane. Biophys J (1976) 6.13
Mattress model of lipid-protein interactions in membranes. Biophys J (1984) 4.33
Accessible surface areas as a measure of the thermodynamic parameters of hydration of peptides. Proc Natl Acad Sci U S A (1987) 3.68
Alamethicin. A rich model for channel behavior. Biophys J (1984) 3.26
Small molecule hydration free energies in explicit solvent: An extensive test of fixed-charge atomistic simulations. J Chem Theory Comput (2009) 2.53
Recent progress in understanding hydrophobic interactions. Proc Natl Acad Sci U S A (2006) 2.37
An equation of state describing hydrophobic interactions. Proc Natl Acad Sci U S A (1976) 2.07
Hydrophobic effect in protein folding and other noncovalent processes involving proteins. Proc Natl Acad Sci U S A (1989) 1.92
Interfacial free energy and the hydrophobic effect. Proc Natl Acad Sci U S A (1979) 1.90
Analytical approximation to the accessible surface area of proteins. Proc Natl Acad Sci U S A (1980) 1.62
Quantification of the hydrophobic interaction by simulations of the aggregation of small hydrophobic solutes in water. Proc Natl Acad Sci U S A (2001) 1.55
Mechanisms of integral membrane protein insertion and folding. J Mol Biol (2014) 1.43
Use of solvent cavity area and number of packed solvent molecules around a solute in regard to hydrocarbon solubilities and hydrophobic interactions. Proc Natl Acad Sci U S A (1977) 1.42
Progress in the prediction of pKa values in proteins. Proteins (2011) 1.36
A unitary anesthetic binding site at high resolution. J Biol Chem (2009) 1.34
Comparison of atomic solvation parametric sets: applicability and limitations in protein folding and binding. Protein Sci (1995) 1.33
The noneffect of a large linear hydrocarbon, squalene, on the phosphatidylcholine packing structure. Biophys J (1977) 1.26
Mechanical properties of the icosahedral shell of southern bean mosaic virus: a molecular dynamics study. Biophys J (2009) 1.26
Isoenthalpic and isoentropic temperatures and the thermodynamics of protein denaturation. Proc Natl Acad Sci U S A (1991) 1.24
Thermodynamics and kinetics of protein incorporation into membranes. Proc Natl Acad Sci U S A (1983) 1.24
A quantitative model of amphetamine action on the 5-HT transporter. Br J Pharmacol (2014) 1.11
SNARE complex zipping as a driving force in the dilation of proteinaceous fusion pores. J Membr Biol (2010) 1.11
Calculation of volume fluctuation for globular protein models. Proc Natl Acad Sci U S A (1983) 1.08
Deep architectures and deep learning in chemoinformatics: the prediction of aqueous solubility for drug-like molecules. J Chem Inf Model (2013) 1.07
Implicit solvation in the self-consistent mean field theory method: sidechain modelling and prediction of folding free energies of protein mutants. J Comput Aided Mol Des (2001) 1.04
A Monte Carlo study of peptide insertion into lipid bilayers: equilibrium conformations and insertion mechanisms. Biophys J (2002) 1.02
Hydrophobicity--shake flasks, protein folding and drug discovery. Curr Top Med Chem (2010) 1.00
Apolar surface area determines the efficiency of translocon-mediated membrane-protein integration into the endoplasmic reticulum. Proc Natl Acad Sci U S A (2011) 0.99
Differences between pair and bulk hydrophobic interactions. Proc Natl Acad Sci U S A (1990) 0.99
Relation between the convergence temperatures Th* and Ts* in protein unfolding. Proc Natl Acad Sci U S A (1992) 0.92
Conformational equilibria of alkanes in aqueous solution: relationship to water structure near hydrophobic solutes. Biophys J (1999) 0.92
Hydrophobicity and charge shape cellular metabolite concentrations. PLoS Comput Biol (2011) 0.91
Identifying mechanisms of interfacial dynamics using single-molecule tracking. Langmuir (2012) 0.90
Absolute hydration free energies of blocked amino acids: implications for protein solvation and stability. Biophys J (2013) 0.90
Water-exclusion and liquid-structure forces in implicit solvation. J Phys Chem B (2011) 0.89
Coarse-grained simulation studies of peptide-induced pore formation. Biophys J (2008) 0.86
Hydrophobic regions on protein surfaces. Derivation of the solvation energy from their area distribution in crystallographic protein structures. Protein Sci (1996) 0.85
Mode matches and their locations in the hydrophobic free energy sequences of peptide ligands and their receptor eigenfunctions. Proc Natl Acad Sci U S A (1997) 0.84
Evidence for a novel mechanism of antimicrobial action of a cyclic R-,W-rich hexapeptide. PLoS One (2015) 0.82
The structure and organization of synthetic putative membranous segments of ROMK1 channel in phospholipid membranes. Biophys J (1997) 0.82
Mutational scanning reveals the determinants of protein insertion and association energetics in the plasma membrane. Elife (2016) 0.81
Pore size matters for potassium channel conductance. J Gen Physiol (2016) 0.80
Anomalous behavior of water inside the SecY translocon. Proc Natl Acad Sci U S A (2015) 0.80
Hydrophobic free energy eigenfunctions of pore, channel, and transporter proteins contain beta-burst patterns. Biophys J (1998) 0.80
Secondary structure, membrane localization, and coassembly within phospholipid membranes of synthetic segments derived from the N- and C-termini regions of the ROMK1 K+ channel. Protein Sci (1996) 0.79
Volume-based solvation models out-perform area-based models in combined studies of wild-type and mutated protein-protein interfaces. BMC Bioinformatics (2008) 0.79
Concanavalin A reveals olfactory receptors which discriminate between alkane odorants on the basis of size. Biochem J (1989) 0.78
Hydration and conformational equilibria of simple hydrophobic and amphiphilic solutes. Biophys J (1998) 0.78
Driving forces for transmembrane alpha-helix oligomerization. Biophys J (2010) 0.77
Reconciling the understanding of 'hydrophobicity' with physics-based models of proteins. J Phys Condens Matter (2016) 0.76
Deep Mutational Scans as a Guide to Engineering High Affinity T Cell Receptor Interactions with Peptide-bound Major Histocompatibility Complex. J Biol Chem (2016) 0.76
Equation of State for Phospholipid Self-Assembly. Biophys J (2016) 0.75
The Hydrophobic Effect in Solute Partitioning and Interfacial Tension. Sci Rep (2016) 0.75
How Water's Properties Are Encoded in Its Molecular Structure and Energies. Chem Rev (2017) 0.75
Some factors in the interpretation of protein denaturation. Adv Protein Chem (1959) 24.89
Hydrophobicity of Long Chain n-Alkyl Carboxylic Acids, as Measured by Their Distribution Between Heptane and Aqueous Solutions. Proc Natl Acad Sci U S A (1973) 3.46
Protein denaturation. Adv Protein Chem (1968) 11.58
The solubility of amino acids and two glycine peptides in aqueous ethanol and dioxane solutions. Establishment of a hydrophobicity scale. J Biol Chem (1971) 8.06
Protein denaturation. C. Theoretical models for the mechanism of denaturation. Adv Protein Chem (1970) 6.90
Characterization of membrane proteins in detergent solutions. Biochim Biophys Acta (1976) 4.84
The estimation of polypeptide chain molecular weights by gel filtration in 6 M guanidine hydrochloride. J Biol Chem (1969) 4.77
The gross conformation of protein-sodium dodecyl sulfate complexes. J Biol Chem (1970) 4.34
The hydrophobic effect and the organization of living matter. Science (1978) 4.03
Binding of dodecyl sulfate to proteins at high binding ratios. Possible implications for the state of proteins in biological membranes. Proc Natl Acad Sci U S A (1970) 4.02
Phospholipid vesicle formation and transmembrane protein incorporation using octyl glucoside. Biochemistry (1981) 3.91
Gel chromatography of proteins in denaturing solvents. Comparison between sodium dodecyl sulfate and guanidine hydrochloride as denaturants. J Biol Chem (1970) 3.67
Properties of detergents. Methods Enzymol (1979) 3.62
Hydrophobicity of Long Chain n-Alkyl Carboxylic Acids, as Measured by Their Distribution Between Heptane and Aqueous Solutions. Proc Natl Acad Sci U S A (1973) 3.46
Viscosity and density of aqueous solutions of urea and guanidine hydrochloride. J Biol Chem (1966) 3.23
Interpretation of protein titration curves. Application to lysozyme. Biochemistry (1972) 3.02
Hydrophobic free energy, micelle formation and the association of proteins with amphiphiles. J Mol Biol (1972) 2.40
Molecular characterization of proteins in detergent solutions. Biochemistry (1974) 2.36
The number of polypeptide chains in rabbit muscle aldolase. Biochemistry (1966) 2.06
Extension of the theory of linked functions to incorporate the effects of protein hydration. J Mol Biol (1969) 1.82
The binding of deoxycholate and Triton X-100 to proteins. J Biol Chem (1973) 1.81
The solubility of amino acids, diglycine, and triglycine in aqueous guanidine hydrochloride solutions. J Biol Chem (1970) 1.77
The critical micelle concentration of L- -dipalmitoylphosphatidylcholine in water and water-methanol solutions. J Mol Biol (1972) 1.68
The binding of deoxycholate, Triton X-100, sodium dodecyl sulfate, and phosphatidylcholine vesicles to cytochrome b5. Biochemistry (1975) 1.68
Determination of molecular weight of the protein moiety in protein-detergent complexes without direct knowledge of detergent binding. Proc Natl Acad Sci U S A (1976) 1.67
Proteins in 6-M guanidine hydrochloride. Demonstration of random coil behavior. J Biol Chem (1966) 1.64
Mechanism of free energy coupling in active transport. Annu Rev Biochem (1983) 1.64
The solubility of amino acids and related compounds in aqueous thylene glycol solutions. J Biol Chem (1965) 1.58
Thermodynamics of the denaturation of lysozyme by guanidine hydrochloride. II. Dependence on denaturant concentration at 25 degrees. Biochemistry (1969) 1.57
Interaction of deoxycholate and of detergents with the coat protein of bacteriophage f1. J Biol Chem (1975) 1.49
Simple model for the chemical potential change of a transported ion in active transport. Proc Natl Acad Sci U S A (1982) 1.47
Isopiestic compositions as a measure of preferential interactions of macromolecules in two-component solvents. Application to proteins in concentrated aqueous cesium chloride and guanidine hydrochloride. J Am Chem Soc (1967) 1.45
Retention of enzyme activity by detergent-solubilized sarcoplasmic Ca2+ -ATPase. Biochemistry (1976) 1.44
Thermodynamics of the unfolding of beta-lactoglobulin A in aqueous urea solutions between 5 and 55 degrees. Biochemistry (1968) 1.40
Denaturation of bovine carbonic anhydrase B by guanidine hydrochloride. A process involving separable sequential conformational transitions. J Biol Chem (1973) 1.38
Kinetic evidence for incorrectly folded intermediate states in the refolding of denatured proteins. Nature (1971) 1.38
Thermodynamics of the denaturation of lysozyme by guanidine hydrochloride. I. Depdendence on pH at 25 degrees. Biochemistry (1969) 1.37
Polypeptide chains from human red blood cell membranes. J Biol Chem (1971) 1.36
Use of gel chromatography for the determination of the Stokes radii of proteins in the presence and absence of detergents. A reexamination. Biochemistry (1976) 1.35
Evidence for residual structure in acid- and heat-denatured proteins. J Biol Chem (1967) 1.34
Proton and hydroxide ion permeability of phospholipid vesicles. Proc Natl Acad Sci U S A (1981) 1.27
Properties of a delipidated, detergent-activated Ca2+--ATPase. Biochemistry (1978) 1.25
Equilibrium and kinetics of the unfolding of lysozyme (muramidase) by guanidine hydrochloride. J Mol Biol (1966) 1.25
Kinetics of unfolding and refolding of proteins. II. Results for cytochrome c. J Mol Biol (1973) 1.21
Kinetics of unfolding and refolding of proteins. I. Mathematical analysis. J Mol Biol (1973) 1.19
Single-chain nature of human serum transferrin. Biochemistry (1970) 1.18
The interaction of a cationic detergent with bovine serum albumin and other proteins. J Biol Chem (1974) 1.14
The size and number of polypeptide chains in human serum low density lipoprotein. J Biol Chem (1972) 1.13
Twenty questions concerning the reaction cycle of the sarcoplasmic reticulum calcium pump. CRC Crit Rev Biochem (1984) 1.13
Equilibrium state of ATP-driven ion pumps in relation to physiological ion concentration gradients. J Gen Physiol (1981) 1.12
Translocation pathway in the catalysis of active transport. Proc Natl Acad Sci U S A (1983) 1.12
Molecular size and conformation of immunoglobulins. Adv Immunol (1970) 1.11
Recovery of native conformation of rabbit immunoglobulin G upon recombination of separately renatured heavy and light chains at near-neutral pH. Biochemistry (1971) 1.10
Intrinsic dissociation constants of aspartyl and glutamyl carboxyl groups. J Biol Chem (1967) 1.08
Acid-base titrations in concentrated guanidine hydrochloride. Dissociation constants of the guamidinium ion and of some amino acids. J Am Chem Soc (1967) 1.08
Hydrogen ion titration curve of lysozyme in 6 M guanidine hydrochloride. Biochemistry (1971) 1.08
Incorporation of membrane potential into theoretical analysis of electrogenic ion pumps. Proc Natl Acad Sci U S A (1985) 1.08
The two-domain structure of cytochrome b5 in deoxycholate solution. Biochemistry (1975) 1.07
Gel-exclusion chromatography on S1000 Sephacryl: application to phospholipid vesicles. Anal Biochem (1983) 1.07
Phospholipid vesicle formation using nonionic detergents with low monomer solubility. Kinetic factors determine vesicle size and permeability. Biochemistry (1984) 1.06
Steady state of an ATP-driven calcium pump: limitations on kinetic and thermodynamic parameters. Proc Natl Acad Sci U S A (1982) 1.06
DISSOCIATION OF HUMAN CO-hemoglobin by urea, guanidine hydrochloride, and other reagents. Biochemistry (1965) 1.05
Molecular weights and hydrophobicity of the polypeptide chain of sarcoplasmic reticulum calcium(II) adenosine triphosphatase and of its primary tryptic fragments. Biochemistry (1976) 1.05
Kinetics of unfolding and refolding of proteins. 3. Results for lysozyme. J Mol Biol (1973) 1.05
Proteins as random coils. 3. Optical rotatory dispersion in 6 M guanidine hydrochloride. J Am Chem Soc (1967) 1.04
Conformational states of a hydrophobic protein. The coat protein of fd bacteriophage. Biochemistry (1978) 1.03
Dopamine receptor subtype agonists and feeding behavior. Obes Res (1995) 1.02
Application of the principle of linked functions to ATP-driven ion pumps: kinetics of activation by ATP. Proc Natl Acad Sci U S A (1985) 1.02
Evidence for a major conformational change of coat protein in assembly of fl bacteriophage. Nature (1976) 1.02
Contributions of heavy and light chains of rabbit immunoglobulin G to antibody activity. I. Binding studies on isolated heavy and light chains. Biochemistry (1972) 1.01
Titration of the histidyl and alpha-amino groups of hemoglobin. J Biol Chem (1966) 0.99
Reactivation of lipid-depleted Ca2+-ATPase by a nonionic detergent. J Biol Chem (1977) 0.99
Association of the major coat protein of fd bacteriophage with phospholipid vesicles. Biochim Biophys Acta (1978) 0.99
Erythrocyte spectrin. Purification in deoxycholate and preliminary characterization. Biochemistry (1976) 0.98
Mechanism of active transport: free energy dissipation and free energy transduction. Proc Natl Acad Sci U S A (1982) 0.98
Equilibrium constants for some steps of the reaction cycle of the sarcoplasmic reticulum calcium pump. Z Naturforsch C (1982) 0.98
Cholesterol in aqueous solution: hydrophobicity and self-association. Biochemistry (1975) 0.96
Urea metabolism and distribution in rabbits treated with neomycin. Am J Physiol (1970) 0.96
Phosphorylation of calcium adenosinetriphosphatase by inorganic phosphate: van't Hoff analysis of enthalpy changes. Biochemistry (1981) 0.96
Proteins as random coils. II. Hydrogen ion titration curve of ribonuclease in 6 M guanidine hydrochloride. J Am Chem Soc (1967) 0.95
Gross conformation of free polypeptide chains from rabbit immunoglobulin G. I. Heavy chain. Biochemistry (1971) 0.94
Conformational change and complementarity in the combination of H and L chains of immunoglobulin-G. Proc Natl Acad Sci U S A (1967) 0.93
A polypeptide chain of very high molecular weight from red blood cell membranes. J Biol Chem (1970) 0.92
Thermodynamic and kinetic cooperativity in ligand binding to multiple sites on a protein: Ca2+ activation of an ATP-driven Ca pump. Proc Natl Acad Sci U S A (1985) 0.91
Gross conformation of free polypeptide chains from rabbit immunoglobulin G. II. Light chain. Biochemistry (1971) 0.91
Equilibrium and kinetics of the denaturation of a homogeneous human immunoglobulin light chain. Biochemistry (1973) 0.90
Variable stoichiometry in active ion transport: theoretical analysis of physiological consequences. Proc Natl Acad Sci U S A (1985) 0.90
Thermodynamics of the denaturation of ribonuclease by guanidine hydrochloride. Biochemistry (1970) 0.89
Phosphorylation of calcium adenosinetriphosphatase by inorganic phosphate: reversible inhibition at high magnesium ion concentrations. Biochemistry (1982) 0.88
Properties of the Fd fragment from rabbit immunoglobulin G. Biochemistry (1972) 0.87
The interaction of polypeptide components of human high density serum lipoprotein with detergents. J Biol Chem (1974) 0.87
Proteins as random coils. IV. Osmotic pressures, second virial coefficients, and unperturbed dimensions in 6 M guanidine hydrochloride. J Am Chem Soc (1967) 0.87
Contributions of heavy and light chains of rabbit immunoglobulin G to antibody activity. II. Binding activities of reconstituted immunoglobulins. Biochemistry (1972) 0.86
Monomeric solubilized sarcoplasmic reticulum Ca pump protein: demonstration of Ca binding and dissociation coupled to ATP hydrolysis. Proc Natl Acad Sci U S A (1984) 0.84
Properties of the soluble product obtained from reoxidation of reduced fragment I from rabbit 7S gamma-immunoglobulin. J Biol Chem (1965) 0.84
Interaction of L-alpha-didecanoyl phosphatidylcholine with the AI polypeptide of high density lipoprotein. Proc Natl Acad Sci U S A (1977) 0.84
Effects of detergent micelles on the recombination reaction of opsin and 11-cis-retinal. Biochemistry (1981) 0.84
Solubilized monomeric sarcoplasmic reticulum Ca pump protein. Phosphorylation by inorganic phosphate. FEBS Lett (1984) 0.84
The impact of visible dental decay on social judgements: comparison of the effects of location and extent of lesion. Int Dent J (2010) 0.83
Thermodynamics of the denaturation of lysozyme by guanidine hydrochloride. 3. Dependence on temperature. Biochemistry (1970) 0.83
Benzodiazepine receptor ligands and the consumption of a highly palatable diet in non-deprived male rats. Psychopharmacology (Berl) (1985) 0.83