Published in Proc Natl Acad Sci U S A on April 03, 2006
Systems biology of cisplatin resistance: past, present and future. Cell Death Dis (2014) 1.74
Regulation of hexokinase binding to VDAC. J Bioenerg Biomembr (2008) 1.73
Misfolded mutant SOD1 directly inhibits VDAC1 conductance in a mouse model of inherited ALS. Neuron (2010) 1.65
The molecular composition of the mitochondrial permeability transition pore. J Mol Cell Cardiol (2009) 1.48
Mitochondrial Ca(2+) and apoptosis. Cell Calcium (2012) 1.36
Uncovering the role of VDAC in the regulation of cell life and death. J Bioenerg Biomembr (2008) 1.34
Oligomerization of the mitochondrial protein voltage-dependent anion channel is coupled to the induction of apoptosis. Mol Cell Biol (2010) 1.30
VDAC1 selectively transfers apoptotic Ca2+ signals to mitochondria. Cell Death Differ (2011) 1.22
VDAC1: from structure to cancer therapy. Front Oncol (2012) 1.16
Voltage-dependent anion channel 1-based peptides interact with Bcl-2 to prevent antiapoptotic activity. J Biol Chem (2009) 1.13
Mitochondrial protein targets of thiol-reactive electrophiles. Chem Res Toxicol (2008) 1.12
The hepatitis E virus Orf3 protein protects cells from mitochondrial depolarization and death. J Biol Chem (2007) 1.07
Nek1 regulates cell death and mitochondrial membrane permeability through phosphorylation of VDAC1. Cell Cycle (2009) 1.03
Structure of the voltage dependent anion channel: state of the art. J Bioenerg Biomembr (2008) 1.01
Hexokinase II detachment from the mitochondria potentiates cisplatin induced cytotoxicity through a caspase-2 dependent mechanism. Cell Cycle (2009) 0.99
Gene expression meta-analysis identifies VDAC1 as a predictor of poor outcome in early stage non-small cell lung cancer. PLoS One (2011) 0.98
Downregulation of mitochondrial porin inhibits cell growth and alters respiratory phenotype in Trypanosoma brucei. Eukaryot Cell (2009) 0.95
Development of an all-in-one lentiviral vector system based on the original TetR for the easy generation of Tet-ON cell lines. PLoS One (2011) 0.92
Silencing VDAC1 Expression by siRNA Inhibits Cancer Cell Proliferation and Tumor Growth In Vivo. Mol Ther Nucleic Acids (2014) 0.92
A role for voltage-dependent anion channel Vdac1 in polyglutamine-mediated neuronal cell death. PLoS One (2007) 0.91
Structure-based analysis of VDAC1 protein: defining oligomer contact sites. J Biol Chem (2011) 0.90
Arabidopsis kinesin KP1 specifically interacts with VDAC3, a mitochondrial protein, and regulates respiration during seed germination at low temperature. Plant Cell (2011) 0.90
Decreased expression of the voltage-dependent anion channel in differentiated PC-12 and SH-SY5Y cells following low-level Pb exposure. Toxicol Sci (2009) 0.88
VDAC1-based peptides: novel pro-apoptotic agents and potential therapeutics for B-cell chronic lymphocytic leukemia. Cell Death Dis (2013) 0.84
Myostatin induces mitochondrial metabolic alteration and typical apoptosis in cancer cells. Cell Death Dis (2013) 0.82
Direct modulation of the outer mitochondrial membrane channel, voltage-dependent anion channel 1 (VDAC1) by cannabidiol: a novel mechanism for cannabinoid-induced cell death. Cell Death Dis (2013) 0.82
CREB1-driven expression of miR-320a promotes mitophagy by down-regulating VDAC1 expression during serum starvation in cervical cancer cells. Oncotarget (2015) 0.82
Revisiting trends on mitochondrial mega-channels for the import of proteins and nucleic acids. J Bioenerg Biomembr (2016) 0.82
Voltage-dependent anion channel 2 of Arabidopsis thaliana (AtVDAC2) is involved in ABA-mediated early seedling development. Int J Mol Sci (2009) 0.81
The Voltage-dependent Anion Channel 1 Mediates Amyloid β Toxicity and Represents a Potential Target for Alzheimer Disease Therapy. J Biol Chem (2015) 0.81
Novel Compounds Targeting the Mitochondrial Protein VDAC1 Inhibit Apoptosis and Protect against Mitochondrial Dysfunction. J Biol Chem (2016) 0.80
Voltage dependent anion channel-1 (VDAC-1) as an anti-cancer target. Cancer Biol Ther (2010) 0.80
Arabidopsis voltage-dependent anion channel 1 (AtVDAC1) is required for female development and maintenance of mitochondrial functions related to energy-transaction. PLoS One (2014) 0.80
Decreased expression of microRNA-320a promotes proliferation and invasion of non-small cell lung cancer cells by increasing VDAC1 expression. Oncotarget (2016) 0.79
Antibiotics and probiotics in chronic pouchitis: a comparative proteomic approach. World J Gastroenterol (2010) 0.79
Characterization of functional reprogramming during osteoclast development using quantitative proteomics and mRNA profiling. Mol Cell Proteomics (2014) 0.79
Redirecting apoptosis to aponecrosis induces selective cytotoxicity to pancreatic cancer cells through increased ROS, decline in ATP levels, and VDAC. Mol Cancer Ther (2013) 0.79
Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells. Proc Natl Acad Sci U S A (2015) 0.78
Clinical implication of voltage-dependent anion channel 1 in uterine cervical cancer and its action on cervical cancer cells. Oncotarget (2016) 0.78
Endosymbiont or host: who drove mitochondrial and plastid evolution? Biol Direct (2011) 0.78
Overexpression of 17β-hydroxysteroid dehydrogenase type 10 increases pheochromocytoma cell growth and resistance to cell death. BMC Cancer (2015) 0.78
Impact of intracellular ion channels on cancer development and progression. Eur Biophys J (2016) 0.78
The voltage-dependent anion channel 1 (AtVDAC1) negatively regulates plant cold responses during germination and seedling development in Arabidopsis and interacts with calcium sensor CBL1. Int J Mol Sci (2013) 0.77
Expression characterization of genes for CMS-C in maize. Protoplasma (2011) 0.76
Protective effect of 14-3-3 antibodies on stressed neuroretinal cells via the mitochondrial apoptosis pathway. BMC Ophthalmol (2015) 0.76
Down regulation of Tim50 in Trypanosoma brucei increases tolerance to oxidative stress. Mol Biochem Parasitol (2015) 0.76
Tissue distribution of olive flounder VDAC2 and its expression in fish cell lines. Fish Physiol Biochem (2015) 0.76
Mitochondrial proteomes of porcine kidney cortex and medulla: foundation for translational proteomics. Clin Exp Nephrol (2015) 0.76
Quantitative proteomic analysis revealed 4-(methylnitrosamino)-1-(3-pyridinyl)-1-butanone-induced up-regulation of 20S proteasome in cultured human fibroblast cells. J Proteome Res (2012) 0.75
Characterization of Oyster Voltage-Dependent Anion Channel 2 (VDAC2) Suggests Its Involvement in Apoptosis and Host Defense. PLoS One (2016) 0.75
The Mitochondrial Voltage-Dependent Anion Channel 1, Ca(2+) Transport, Apoptosis, and Their Regulation. Front Oncol (2017) 0.75
Mps1 kinase regulates tumor cell viability via its novel role in mitochondria. Cell Death Dis (2016) 0.75
Chi-square analysis of the reduction of ATP levels in L-02 hepatocytes by hexavalent chromium. Braz J Med Biol Res (2012) 0.75
Mitochondrial Porin Isoform AtVDAC1 Regulates the Competence of Arabidopsis thaliana to Agrobacterium-Mediated Genetic Transformation. Mol Cells (2016) 0.75
A Single Talent Immunogenic Membrane Antigen and Novel Prognostic Predictor: voltage-dependent anion channel 1 (VDAC1) in Pancreatic Cancer. Sci Rep (2016) 0.75
Nutrition and Training Influences on the Regulation of Mitochondrial Adenosine Diphosphate Sensitivity and Bioenergetics. Sports Med (2017) 0.75
News about VDAC1 in Hypoxia. Front Oncol (2016) 0.75
Molecular analysis of Culex quinquefasciatus larvae responses to Lysinibacillus sphaericus Bin toxin. PLoS One (2017) 0.75
Crystal structural characterization reveals novel oligomeric interactions of human voltage-dependent anion channel 1. Protein Sci (2017) 0.75
Protein measurement with the Folin phenol reagent. J Biol Chem (1951) 1743.91
Mechanisms of gene silencing by double-stranded RNA. Nature (2004) 16.82
BCL-2 family members and the mitochondria in apoptosis. Genes Dev (1999) 13.52
Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC. Nature (1999) 8.70
The mitochondrial permeability transition pore and its role in cell death. Biochem J (1999) 7.72
Revealing the world of RNA interference. Nature (2004) 5.92
Mitochondrial control of apoptosis. Immunol Today (1997) 4.74
Mitochondrial binding of hexokinase II inhibits Bax-induced cytochrome c release and apoptosis. J Biol Chem (2001) 3.33
VDAC: the channel at the interface between mitochondria and the cytosol. Mol Cell Biochem (2004) 3.26
Control of respiration and ATP synthesis in mammalian mitochondria and cells. Biochem J (1992) 2.66
Curcumin (diferuloylmethane) inhibits constitutive and IL-6-inducible STAT3 phosphorylation in human multiple myeloma cells. J Immunol (2003) 2.44
Chemopreventive and therapeutic effects of curcumin. Cancer Lett (2004) 2.40
In self-defence: hexokinase promotes voltage-dependent anion channel closure and prevents mitochondria-mediated apoptotic cell death. Biochem J (2004) 2.30
Tetracycline repressor, tetR, rather than the tetR-mammalian cell transcription factor fusion derivatives, regulates inducible gene expression in mammalian cells. Hum Gene Ther (1998) 2.29
Regulation of metabolite flux through voltage-gating of VDAC channels. J Membr Biol (1997) 1.94
ATP flux is controlled by a voltage-gated channel from the mitochondrial outer membrane. J Biol Chem (1996) 1.84
Calcium binding and translocation by the voltage-dependent anion channel: a possible regulatory mechanism in mitochondrial function. Biochem J (2001) 1.70
The voltage-dependent anion channel-1 modulates apoptotic cell death. Cell Death Differ (2005) 1.63
Essential role of the voltage-dependent anion channel (VDAC) in mitochondrial permeability transition pore opening and cytochrome c release induced by arsenic trioxide. Oncogene (2004) 1.57
Small-interfering RNA-induced androgen receptor silencing leads to apoptotic cell death in prostate cancer. Mol Cancer Ther (2005) 1.53
Two novel pathogenic mitochondrial DNA mutations affecting organelle number and protein synthesis. Is the tRNA(Leu(UUR)) gene an etiologic hot spot? J Clin Invest (1993) 1.48
The voltage-dependent anion channel: characterization, modulation, and role in mitochondrial function in cell life and death. Cell Biochem Biophys (2003) 1.33
Bax-dependent regulation of Bak by voltage-dependent anion channel 2. J Biol Chem (2005) 1.32
VDAC is a conserved element of death pathways in plant and animal systems. Biochim Biophys Acta (2003) 1.29
Characterization of citrate synthase from Geobacter sulfurreducens and evidence for a family of citrate synthases similar to those of eukaryotes throughout the Geobacteraceae. Appl Environ Microbiol (2005) 1.20
Bcl-2 constitutively suppresses p53-dependent apoptosis in colorectal cancer cells. Genes Dev (2003) 1.20
Inhibition of cell proliferation and the action mechanisms of arsenic trioxide (As2O3) on human breast cancer cells. J Cell Biochem (2004) 1.18
VDAC/porin is present in sarcoplasmic reticulum from skeletal muscle. FEBS Lett (1996) 1.09
Ruthenium red, inhibitor of mitochondrial Ca2+ uniporter, inhibits curcumin-induced apoptosis via the prevention of intracellular Ca2+ depletion and cytochrome c release. Biochem Biophys Res Commun (2003) 1.08
Curcumin, a potent anti-tumor reagent, is a novel histone deacetylase inhibitor regulating B-NHL cell line Raji proliferation. Acta Pharmacol Sin (2005) 1.08
The role of mitochondrial transport in energy metabolism. Mitochondrion (2003) 1.03
Further studies on the coupling of mitochondrially bound hexokinase to intramitochondrially compartmented ATP, generated by oxidative phosphorylation. Arch Biochem Biophys (1998) 1.02
RNA interference: a potent tool for gene-specific therapeutics. Am J Transplant (2004) 0.99
Studies on human porin. VI. Production and characterization of eight monoclonal mouse antibodies against the human VDAC "Porin 31HL" and their application for histotopological studies in human skeletal muscle. Biol Chem Hoppe Seyler (1991) 0.99
Intracellular Ca2+ release mediates ursolic acid-induced apoptosis in human leukemic HL-60 cells. Int J Cancer (1997) 0.94
Arsenic trioxide triggers a regulated form of caspase-independent necrotic cell death via the mitochondrial death pathway. Oncogene (2005) 0.92
Small interfering RNA for experimental cancer therapy. Curr Opin Mol Ther (2005) 0.90
Isolation and characterization of mitochondria from human B lymphoblastoid cell lines. Biochem Biophys Res Commun (1992) 0.89
Studies on human porin. XII. Eight monoclonal mouse anti-"porin 31HL" antibodies discriminate type 1 and type 2 mammalian porin channels/VDACs in western blotting and enzyme-linked immunosorbent assays. Biochem Med Metab Biol (1994) 0.88
Voltage-dependent anion channel proteins in synaptosomes of the torpedo electric organ: immunolocalization, purification, and characterization. J Bioenerg Biomembr (1998) 0.85
Curcumin decreases cell proliferation rates through BTG2-mediated cyclin D1 down-regulation in U937 cells. Int J Oncol (2005) 0.85
Pivotal role of mitochondrial Ca(2+) in microcystin-induced mitochondrial permeability transition in rat hepatocytes. Biochem Biophys Res Commun (2001) 0.84
Apoptosis and differentiation induced by staurosporine in granulosa tumor cells is coupled with activation of JNK and suppression of p38 MAPK. Int J Oncol (2005) 0.82
Potential application of the ATP cell viability assay in the measurement of intrinsic radiosensitivity in cervical cancer. Gynecol Oncol (2005) 0.80
NCLX is an essential component of mitochondrial Na+/Ca2+ exchange. Proc Natl Acad Sci U S A (2009) 2.36
In self-defence: hexokinase promotes voltage-dependent anion channel closure and prevents mitochondria-mediated apoptotic cell death. Biochem J (2004) 2.30
The VDAC1 N-terminus is essential both for apoptosis and the protective effect of anti-apoptotic proteins. J Cell Sci (2009) 1.65
Misfolded mutant SOD1 directly inhibits VDAC1 conductance in a mouse model of inherited ALS. Neuron (2010) 1.65
Hexokinase-I protection against apoptotic cell death is mediated via interaction with the voltage-dependent anion channel-1: mapping the site of binding. J Biol Chem (2008) 1.65
Oligomeric states of the voltage-dependent anion channel and cytochrome c release from mitochondria. Biochem J (2005) 1.43
Pelizaeus-Merzbacher-like disease caused by AIMP1/p43 homozygous mutation. Am J Hum Genet (2010) 1.32
Oligomerization of the mitochondrial protein voltage-dependent anion channel is coupled to the induction of apoptosis. Mol Cell Biol (2010) 1.30
Mutations disrupting selenocysteine formation cause progressive cerebello-cerebral atrophy. Am J Hum Genet (2010) 1.21
Voltage-dependent anion channel 1-based peptides interact with hexokinase to prevent its anti-apoptotic activity. J Biol Chem (2008) 1.13
Voltage-dependent anion channel 1-based peptides interact with Bcl-2 to prevent antiapoptotic activity. J Biol Chem (2009) 1.13
Mediation of the antiapoptotic activity of Bcl-xL protein upon interaction with VDAC1 protein. J Biol Chem (2012) 1.11
Meconium ileus caused by mutations in GUCY2C, encoding the CFTR-activating guanylate cyclase 2C. Am J Hum Genet (2012) 1.08
ZNF750 is expressed in differentiated keratinocytes and regulates epidermal late differentiation genes. PLoS One (2012) 0.99
Nucleotide-binding sites in the voltage-dependent anion channel: characterization and localization. J Biol Chem (2005) 0.97
The desmosterolosis phenotype: spasticity, microcephaly and micrognathia with agenesis of corpus callosum and loss of white matter. Eur J Hum Genet (2011) 0.97
Expression of a truncated active form of VDAC1 in lung cancer associates with hypoxic cell survival and correlates with progression to chemotherapy resistance. Cancer Res (2012) 0.95
ATP-binding sites in brain p97/VCP (valosin-containing protein), a multifunctional AAA ATPase. Biochem J (2003) 0.93
Structure-based analysis of VDAC1: N-terminus location, translocation, channel gating and association with anti-apoptotic proteins. Biochem J (2012) 0.93
Downregulation of voltage-dependent anion channel-1 expression by RNA interference prevents cancer cell growth in vivo. Cancer Biol Ther (2010) 0.93
Structure-based analysis of VDAC1 protein: defining oligomer contact sites. J Biol Chem (2011) 0.90
The role of calcium in VDAC1 oligomerization and mitochondria-mediated apoptosis. Biochim Biophys Acta (2013) 0.90
VDAC1 cysteine residues: topology and function in channel activity and apoptosis. Biochem J (2010) 0.88
Localization of the voltage-dependent anion channel-1 Ca2+-binding sites. Cell Calcium (2006) 0.88
Characterization of DIDS-sensitive ATP accumulation in brain synaptic vesicles. FEBS Lett (2006) 0.87
Dominant-negative VDAC1 mutants reveal oligomeric VDAC1 to be the active unit in mitochondria-mediated apoptosis. Biochem J (2010) 0.85
Retinal voltage-dependent anion channel: characterization and cellular localization. Invest Ophthalmol Vis Sci (2002) 0.84
A photoactivable probe for calcium binding proteins. Chem Biol (2005) 0.83
VPS53 mutations cause progressive cerebello-cerebral atrophy type 2 (PCCA2). J Med Genet (2014) 0.83
An N-terminal nucleotide-binding site in VDAC1: involvement in regulating mitochondrial function. J Cell Physiol (2007) 0.83
Hyperchlorhidrosis caused by homozygous mutation in CA12, encoding carbonic anhydrase XII. Am J Hum Genet (2010) 0.82
The synaptic vesicle protein synaptophysin: purification and characterization of its channel activity. Biophys J (2002) 0.82
Glutamate interacts with VDAC and modulates opening of the mitochondrial permeability transition pore. J Bioenerg Biomembr (2004) 0.82
Mapping the ruthenium red-binding site of the voltage-dependent anion channel-1. Cell Calcium (2007) 0.80
The P4 promoter of the parvovirus minute virus of mice is developmentally regulated in transgenic P4-LacZ mice. Virology (2003) 0.79
Measurement of mitochondrial Ca2+ transport mediated by three transport proteins: VDAC1, the Na+/Ca2+ exchanger, and the Ca2+ uniporter. Cold Spring Harb Protoc (2014) 0.78
Purification of VDAC1 from rat liver mitochondria. Cold Spring Harb Protoc (2014) 0.77
Assays of mitochondrial Ca2+ transport and Ca2+ efflux via the MPTP. Cold Spring Harb Protoc (2014) 0.76
Reconstitution of purified VDAC1 into a lipid bilayer and recording of channel conductance. Cold Spring Harb Protoc (2014) 0.76
Silencing VDAC1 Expression by siRNA Inhibits Cancer Cell Proliferation and Tumor Growth In Vivo. Mol Ther Nucleic Acids (2017) 0.75
New fluorescent reagents specific for Ca(2+)-binding proteins. Biochem Biophys Res Commun (2012) 0.75
Azido ruthenium: a new photoreactive probe for calcium-binding proteins. Nat Protoc (2006) 0.75
Assay of Ca2+ transport by VDAC1 reconstituted into liposomes. Cold Spring Harb Protoc (2014) 0.75
Mitochondrial Na+/Ca2+ exchange assays. Cold Spring Harb Protoc (2014) 0.75