Acute and prolonged effects of TNF-alpha on the expression and secretion of inflammation-related adipokines by human adipocytes differentiated in culture.

PubWeight™: 1.06‹?› | Rank: Top 15%

🔗 View Article (PMID 16586095)

Published in Pflugers Arch on April 04, 2006

Authors

Bohan Wang1, Paul Trayhurn

Author Affiliations

1: Obesity Biology Unit, Liverpool Centre for Nutritional Genomics and Liverpool Obesity Research Network, School of Clinical Sciences, University of Liverpool, Liverpool L69 3GA, UK.

Articles citing this

Macrophages block insulin action in adipocytes by altering expression of signaling and glucose transport proteins. Am J Physiol Endocrinol Metab (2006) 3.04

Dysregulation of the expression and secretion of inflammation-related adipokines by hypoxia in human adipocytes. Pflugers Arch (2007) 2.39

Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases. BMC Med Genomics (2009) 2.36

Adipose tissue: the new endocrine organ? A review article. Dig Dis Sci (2008) 2.26

Migraine and obesity: epidemiology, mechanisms, and implications. Headache (2009) 2.05

Inflammation as a Link between Obesity and Metabolic Syndrome. J Nutr Metab (2012) 1.47

Regulation of HIF-1{alpha} activity in adipose tissue by obesity-associated factors: adipogenesis, insulin, and hypoxia. Am J Physiol Endocrinol Metab (2011) 1.39

Microarray analysis identifies matrix metalloproteinases (MMPs) as key genes whose expression is up-regulated in human adipocytes by macrophage-conditioned medium. Pflugers Arch (2009) 1.21

Integration of hormonal and nutrient signals that regulate leptin synthesis and secretion. Am J Physiol Endocrinol Metab (2009) 1.17

Obesity and inflammation: epidemiology, risk factors, and markers of inflammation. Int J Endocrinol (2013) 1.12

Oxidative stress in obesity: a critical component in human diseases. Int J Mol Sci (2014) 1.08

Endotoxaemia leads to major increases in inflammatory adipokine gene expression in white adipose tissue of mice. Pflugers Arch (2008) 0.98

Differential effects of 1α,25-dihydroxycholecalciferol on MCP-1 and adiponectin production in human white adipocytes. Eur J Nutr (2011) 0.95

Obesity, Oxidative Stress, Adipose Tissue Dysfunction, and the Associated Health Risks: Causes and Therapeutic Strategies. Metab Syndr Relat Disord (2015) 0.94

Integrative neurobiology of metabolic diseases, neuroinflammation, and neurodegeneration. Front Neurosci (2015) 0.94

Downregulation of zinc-{alpha}2-glycoprotein in adipose tissue and liver of obese ob/ob mice and by tumour necrosis factor-alpha in adipocytes. J Endocrinol (2009) 0.94

The relationship between dietary fatty acids and inflammatory genes on the obese phenotype and serum lipids. Nutrients (2013) 0.93

PCR arrays identify metallothionein-3 as a highly hypoxia-inducible gene in human adipocytes. Biochem Biophys Res Commun (2008) 0.91

Adipocytes enhance the proliferation of human leiomyoma cells via TNF-α proinflammatory cytokine. Reprod Sci (2011) 0.91

Juvenile obesity aggravates disease severity in a rat model of atopic dermatitis. Allergy Asthma Immunol Res (2014) 0.86

Nutrigenomics, beta-cell function and type 2 diabetes. Curr Genomics (2007) 0.84

The role of inflammatory pathways in cancer-associated cachexia and radiation resistance. Mol Cancer Res (2013) 0.83

[Adipokine update - new molecules, new functions]. Wien Med Wochenschr (2010) 0.81

Obesity and the Endometrium: Adipocyte-Secreted Proinflammatory TNF α Cytokine Enhances the Proliferation of Human Endometrial Glandular Cells. Obstet Gynecol Int (2013) 0.80

Oligofructose supplementation (10%) during pregnancy and lactation does not change the inflammatory effect of concurrent trans fatty acid ingestion on 21-day-old offspring. Lipids Health Dis (2013) 0.79

Adipokine expression and secretion by canine adipocytes: stimulation of inflammatory adipokine production by LPS and TNFalpha. Pflugers Arch (2010) 0.78

Characterization of In Vitro Engineered Human Adipose Tissues: Relevant Adipokine Secretion and Impact of TNF-α. PLoS One (2015) 0.75

Articles cited by this

Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest (2003) 41.22

Positional cloning of the mouse obese gene and its human homologue. Nature (1994) 38.85

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest (2003) 32.01

Leptin and the regulation of body weight in mammals. Nature (1998) 14.84

Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia. J Clin Endocrinol Metab (2001) 9.53

AdipoQ is a novel adipose-specific gene dysregulated in obesity. J Biol Chem (1996) 6.93

Adipokines: inflammation and the pleiotropic role of white adipose tissue. Br J Nutr (2004) 6.31

Monocyte chemoattractant protein 1 in obesity and insulin resistance. Proc Natl Acad Sci U S A (2003) 6.06

Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance. Am J Physiol Endocrinol Metab (2001) 5.76

PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein. Diabetes (2001) 5.18

Minireview: The adipocyte--at the crossroads of energy homeostasis, inflammation, and atherosclerosis. Endocrinology (2003) 4.28

Potential role of TNF-alpha in the pathogenesis of insulin resistance and type 2 diabetes. Trends Endocrinol Metab (2000) 3.42

Physiological role of adipose tissue: white adipose tissue as an endocrine and secretory organ. Proc Nutr Soc (2001) 3.00

Characterization of a human preadipocyte cell strain with high capacity for adipose differentiation. Int J Obes Relat Metab Disord (2001) 2.94

Inflammatory pathways and insulin action. Int J Obes Relat Metab Disord (2003) 2.94

The biology of white adipocyte proliferation. Obes Rev (2001) 2.94

Pro-inflammatory cytokines and adipose tissue. Proc Nutr Soc (2001) 2.54

The adipocyte: a model for integration of endocrine and metabolic signaling in energy metabolism regulation. Am J Physiol Endocrinol Metab (2001) 2.46

Production and release of macrophage migration inhibitory factor from human adipocytes. Endocrinology (2004) 2.00

The role of TNF alpha in adipocyte metabolism. Semin Cell Dev Biol (1999) 1.95

Regulation of adipocytokines and insulin resistance. Diabetologia (2003) 1.90

Hormonal regulation of adiponectin gene expression in 3T3-L1 adipocytes. Biochem Biophys Res Commun (2002) 1.86

Adiponectin gene expression and secretion is inhibited by interleukin-6 in 3T3-L1 adipocytes. Biochem Biophys Res Commun (2003) 1.82

Chronic interleukin-6 (IL-6) treatment increased IL-6 secretion and induced insulin resistance in adipocyte: prevention by rosiglitazone. Biochem Biophys Res Commun (2003) 1.79

Chemokines control fat accumulation and leptin secretion by cultured human adipocytes. Mol Cell Endocrinol (2001) 1.75

Innervation of mammalian white adipose tissue: implications for the regulation of total body fat. Am J Physiol (1998) 1.70

Adipose tissue, insulin action and vascular disease: inflammatory signals. Int J Obes Relat Metab Disord (2003) 1.63

Expression and secretion of inflammation-related adipokines by human adipocytes differentiated in culture: integrated response to TNF-alpha. Am J Physiol Endocrinol Metab (2004) 1.51

Significance of chemokines and activated platelets in patients with diabetes. Clin Exp Immunol (2000) 1.26

Tumor necrosis factor-alpha contributes to obesity-related hyperleptinemia by regulating leptin release from adipocytes. J Clin Invest (1997) 1.25

Effects of hypoxia on the expression of proangiogenic factors in differentiated 3T3-F442A adipocytes. Int J Obes Relat Metab Disord (2003) 1.22

Tumor necrosis factor-alpha induces apoptosis of human adipose cells. Diabetes (1997) 1.21

Local sympathetic denervation of white adipose tissue in rats induces preadipocyte proliferation without noticeable changes in metabolism. Endocrinology (1993) 1.19

Targets for TNF-alpha-induced lipolysis in human adipocytes. Biochem Biophys Res Commun (2004) 1.16

Influences of ionomycin, dibutyryl-cycloAMP and tumour necrosis factor-alpha on intracellular amount and secretion of apM1 in differentiating primary human preadipocytes. Horm Metab Res (2001) 1.11

Modulation of adipocyte differentiation by tumor necrosis factor and transforming growth factor beta. J Cell Biol (1989) 1.07

White adipocyte vascular endothelial growth factor: regulation by insulin. Endocrinology (2002) 1.04

Tumor necrosis factor-alpha-induced insulin resistance in adipocytes. Proc Soc Exp Biol Med (2000) 1.03

Interleukin (IL)-6 mRNA expression is stimulated by insulin, isoproterenol, tumour necrosis factor alpha, growth hormone, and IL-6 in 3T3-L1 adipocytes. Horm Metab Res (2003) 0.99

NGF gene expression and secretion in white adipose tissue: regulation in 3T3-L1 adipocytes by hormones and inflammatory cytokines. Am J Physiol Endocrinol Metab (2004) 0.92

Identification of macrophage migration inhibitory factor in adipose tissue and its induction by tumor necrosis factor-alpha. Biochem Biophys Res Commun (1997) 0.91

Expression of plasminogen activator inhibitor-1 in human adipose tissue: a role for TNF-alpha? Atherosclerosis (1999) 0.91

Tumour necrosis factor-alpha exerts dual effects on human adipose leptin synthesis and release. Mol Cell Endocrinol (2000) 0.89

TNF-alpha and insulin, alone and synergistically, induce plasminogen activator inhibitor-1 expression in adipocytes. Am J Physiol (1999) 0.87

Secretion of tumor necrosis factor-alpha shows a strong relationship to insulin-stimulated glucose transport in human adipose tissue. Diabetes (2000) 0.79

Stimulation of PAI-1 and adipokines by glucose in human adipose tissue in vitro. Biochem Biophys Res Commun (2003) 0.78

Articles by these authors

Glucose transporters (GLUT and SGLT): expanded families of sugar transport proteins. Br J Nutr (2003) 2.62

Dysregulation of the expression and secretion of inflammation-related adipokines by hypoxia in human adipocytes. Pflugers Arch (2007) 2.39

IL-33, a recently identified interleukin-1 gene family member, is expressed in human adipocytes. Biochem Biophys Res Commun (2009) 1.86

Cellular hypoxia and adipose tissue dysfunction in obesity. Proc Nutr Soc (2009) 1.71

Zinc-alpha2-glycoprotein, a lipid mobilizing factor, is expressed in adipocytes and is up-regulated in mice with cancer cachexia. Proc Natl Acad Sci U S A (2004) 1.55

Expression and secretion of inflammation-related adipokines by human adipocytes differentiated in culture: integrated response to TNF-alpha. Am J Physiol Endocrinol Metab (2004) 1.51

Identification of macrophage inhibitory cytokine-1 in adipose tissue and its secretion as an adipokine by human adipocytes. Endocrinology (2008) 1.34

Circulating nerve growth factor levels in relation to obesity and the metabolic syndrome in women. Eur J Endocrinol (2007) 1.31

Vitamin D signalling in adipose tissue. Br J Nutr (2012) 1.28

The case for strategic international alliances to harness nutritional genomics for public and personal health. Br J Nutr (2005) 1.24

Zinc-alpha2-glycoprotein, a lipid mobilizing factor, is expressed and secreted by human (SGBS) adipocytes. FEBS Lett (2005) 1.24

Microarray analysis identifies matrix metalloproteinases (MMPs) as key genes whose expression is up-regulated in human adipocytes by macrophage-conditioned medium. Pflugers Arch (2009) 1.21

Hypoxia induces leptin gene expression and secretion in human preadipocytes: differential effects of hypoxia on adipokine expression by preadipocytes. J Endocrinol (2008) 1.18

Hypoxia stimulates lactate release and modulates monocarboxylate transporter (MCT1, MCT2, and MCT4) expression in human adipocytes. Pflugers Arch (2009) 1.17

The pro-inflammatory cytokine IL-18 is expressed in human adipose tissue and strongly upregulated by TNFalpha in human adipocytes. Biochem Biophys Res Commun (2005) 1.06

Rhythmic diurnal gene expression in human adipose tissue from individuals who are lean, overweight, and type 2 diabetic. Diabetes (2011) 1.05

Hypoxia increases expression of selective facilitative glucose transporters (GLUT) and 2-deoxy-D-glucose uptake in human adipocytes. Biochem Biophys Res Commun (2007) 1.03

Obesity, its associated disorders and the role of inflammatory adipokines in companion animals. Vet J (2010) 1.03

Ontogenic loss of brown adipose tissue sensitivity to beta-adrenergic stimulation in the ovine. Endocrinology (2006) 1.02

Expression of Class III facilitative glucose transporter genes (GLUT-10 and GLUT-12) in mouse and human adipose tissues. Biochem Biophys Res Commun (2003) 0.99

Endotoxaemia leads to major increases in inflammatory adipokine gene expression in white adipose tissue of mice. Pflugers Arch (2008) 0.98

Regulation of haptoglobin gene expression in 3T3-L1 adipocytes by cytokines, catecholamines, and PPARgamma. Biochem Biophys Res Commun (2004) 0.98

A microarray analysis of the hypoxia-induced modulation of gene expression in human adipocytes. Arch Physiol Biochem (2012) 0.96

New insights into adipose tissue atrophy in cancer cachexia. Proc Nutr Soc (2009) 0.94

NGF gene expression and secretion in white adipose tissue: regulation in 3T3-L1 adipocytes by hormones and inflammatory cytokines. Am J Physiol Endocrinol Metab (2004) 0.92

PCR arrays identify metallothionein-3 as a highly hypoxia-inducible gene in human adipocytes. Biochem Biophys Res Commun (2008) 0.91

Regulation of angiopoietin-like protein 4/fasting-induced adipose factor (Angptl4/FIAF) expression in mouse white adipose tissue and 3T3-L1 adipocytes. Br J Nutr (2007) 0.90

Inflammatory gene expression patterns revealed by DNA microarray analysis in TNF-alpha-treated SGBS human adipocytes. Yonsei Med J (2006) 0.90

Postnatal expression of zinc-alpha2-glycoprotein in rat white and brown adipose tissue. Mol Cell Endocrinol (2007) 0.87

Regulation of adipose tissue metabolism in cancer cachexia. Curr Opin Clin Nutr Metab Care (2008) 0.86

Modulation of adipokine production, glucose uptake and lactate release in human adipocytes by small changes in oxygen tension. Pflugers Arch (2011) 0.86

Contrasts between the effects of zinc-α2-glycoprotein, a putative β3/2-adrenoceptor agonist and the β3/2-adrenoceptor agonist BRL35135 in C57Bl/6 (ob/ob) mice. J Endocrinol (2013) 0.85

Fatty acids and hypoxia stimulate the expression and secretion of the adipokine ANGPTL4 (angiopoietin-like protein 4/ fasting-induced adipose factor) by human adipocytes. J Nutrigenet Nutrigenomics (2011) 0.84

Prostaglandin D2 and J2-series (PGJ2, Delta12-PGJ2) prostaglandins stimulate IL-6 and MCP-1, but inhibit leptin, expression and secretion by 3T3-L1 adipocytes. Pflugers Arch (2006) 0.84

Lactate and the GPR81 receptor in metabolic regulation: implications for adipose tissue function and fatty acid utilisation by muscle during exercise. Br J Nutr (2011) 0.82

The adipokine zinc-α2-glycoprotein activates AMP kinase in human primary skeletal muscle cells. Arch Physiol Biochem (2011) 0.81

Stimulation of inflammatory gene expression in human preadipocytes by macrophage-conditioned medium: upregulation of IL-6 production by macrophage-derived IL-1β. Mol Cell Endocrinol (2011) 0.80

Detection of thermogenesis in rodents in response to anti-obesity drugs and genetic modification. Front Physiol (2013) 0.79

Stimulation of NGF expression and secretion in 3T3-L1 adipocytes by prostaglandins PGD2, PGJ2, and Delta12-PGJ2. Am J Physiol Endocrinol Metab (2005) 0.79

Resistin and RELM-alpha gene expression in white adipose tissue of lactating mice. Biochem Biophys Res Commun (2002) 0.79

Adipokine expression and secretion by canine adipocytes: stimulation of inflammatory adipokine production by LPS and TNFalpha. Pflugers Arch (2010) 0.78

Nutritional genomics - "Nutrigenomics". Br J Nutr (2003) 0.77

Obesity -- what role now for nutritional science? Br J Nutr (2005) 0.77

Adipose tissue. Editorial. Arch Physiol Biochem (2011) 0.76

HIF-1alpha protein rather than mRNA as a marker of hypoxia in adipose tissue in obesity: focus on "inflammation is associated with a decrease of lipogenic factors in omental fat in women," by Poulain-Godefroy et al. Am J Physiol Regul Integr Comp Physiol (2008) 0.76

Of genes and genomes - and dark matter. Br J Nutr (2004) 0.75

Comment on: Hosagai et al. (2007) Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation: Diabetes 56:901-911. Diabetes (2007) 0.75

White adipose tissue grafts--keeping in contact. Am J Physiol Regul Integr Comp Physiol (2005) 0.75

Obesity in the Inuit--adipose tissue and ischaemic heart disease. Int J Circumpolar Health (2009) 0.75

Tempus fugit--evolution and current impact of the British Journal of Nutrition. Br J Nutr (2005) 0.75

The public library of science and "open access" to the scientific literature. Br J Nutr (2002) 0.75

Brown fat - hotting up again. Obes Facts (2009) 0.75

Recent highly cited articles in the British Journal of Nutrition. Br J Nutr (2003) 0.75

Obesity in the Inuit - Adipose tissue and ischaemic heart desease. Int J Circumpolar Health (2009) 0.75