Published in Proc Natl Acad Sci U S A on June 01, 1959
The preparation and some properties of purified antibody specific for the 2,4-dinitrophenyl group. J Exp Med (1960) 5.58
A cytochemical study on the pancreas of the guinea pig. 6. Release of enzymes and ribonucleic acid from ribonucleoprotein particles. J Biophys Biochem Cytol (1960) 2.24
Specific inhibition of wheal-and-erythema responses with univalent haptens and univalent antibody fragments. J Exp Med (1960) 2.13
Immunoglobulin synthesis and secretion. II. Radioautographic studies of sites of addition of carbohydrate moieties and intracellular transport. J Cell Biol (1970) 1.78
Localization of antibodies in plasma cells by electron microscopy. J Exp Med (1963) 1.75
The synthesis and secretion of gamma-globulin by lymph node cells. 3. The slow acquisition of the carbohydrate moiety of gamma-globulin and its relationship to secretion. Proc Natl Acad Sci U S A (1968) 1.48
THE SYNTHESIS AND SECRETION OF gamma-GLOBULINS BY LYMPH NODE CELLS, I. THE MICROSOMAL COMPARTMENTALIZATION OF gamma-GLOBULINS. Proc Natl Acad Sci U S A (1967) 1.41
The solubilization of microsomal antibody activity by the specific interaction between the crystallizable fraction of gamma-globulin and lymphnode microsomes. Proc Natl Acad Sci U S A (1961) 1.17
THE INTRACELLULAR DISTRIBUTION OF GAMMA GLOBULIN IN A MOUSE PLASMA CELL TUMOR (X5563) AS REVEALED BY FLUORESCENCE AND ELECTRON MICROSCOPY. J Exp Med (1962) 1.04
Synthesis and secretion of gamma-globulin by lymph node cells, VIII. Order of synthesis of the interchain disulfide linkages of immunoglobulins. Proc Natl Acad Sci U S A (1970) 0.99
Synthesis of gamma G antibody and immunoglobulin on polyribosomes in a cell-free system. Proc Natl Acad Sci U S A (1967) 0.96
ANTIGENIC PROPERTIES OF MICROSOMES FROM GUINEA-PIG SPLEEN, LIVER AND LYMPH NODES. Immunology (1964) 0.93
Synthesis and secretion of gammaglobulin by lymph node cells: the acquisition of carbohydrate residues of immunoglobulin in relation to interchain disulfide bond formation (heavy and light chains-murine myeloma-mannose-glucosamine-galactose). Proc Natl Acad Sci U S A (1972) 0.86
Two classes of spleen ribosomes with different sensitivities to chloramphenicol. Proc Natl Acad Sci U S A (1966) 0.83
Differentiation of lymphoid cells: the non-mitogenic induction of immunoglobulin production by thymus cell extract and thymus cell culture filtrate. Immunology (1976) 0.78
THEORIES OF ANTIBODY FORMATION: A REVIEW. Yale J Biol Med (1964) 0.75
The nature of polysomes isolated from spleen cells of rats stimulated by antigen. Proc Natl Acad Sci U S A (1967) 0.75
Diarrhoea due to deficiency of sugar-splitting intestinal enzymes. Br Med J (1961) 0.75
Studies on antibody production. I. A method for the histochemical demonstration of specific antibody and its application to a study of the hyperimmune rabbit. J Exp Med (1955) 16.36
Studies on cytoplasmic ribonucleoprotein particles from the liver of the rat. J Biol Chem (1955) 9.65
Relation between phosphate energy donors and incorporation of labeled amino acids into proteins. J Biol Chem (1954) 7.91
Incorporation of C14-amino acids into ribonucleoprotein particles from the Ehrlich mouse ascites tumor. J Biol Chem (1957) 4.51
A serum albumin precursor in cytoplasmic particles. J Biol Chem (1957) 2.63
Binding of monomeric immunoglobulins to Fc receptors of mouse macrophages. J Exp Med (1975) 5.19
Complete primary structure of a heterodimeric T-cell receptor deduced from cDNA sequences. Nature (1984) 5.19
Mouse myeloma proteins with antihapten antibody acitivity. The protein produced by plasma cell tumor MOPC-315. Biochemistry (1968) 4.83
Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response. Immunity (1996) 4.68
Homeostasis-stimulated proliferation drives naive T cells to differentiate directly into memory T cells. J Exp Med (2000) 4.54
EXCITATION ENERGY TRANSFER AND THE QUANTITATIVE STUDY OF THE ANTIBODY HAPTEN REACTION. Proc Natl Acad Sci U S A (1960) 4.43
Structure, organization, and somatic rearrangement of T cell gamma genes. Cell (1985) 3.49
A third rearranged and expressed gene in a clone of cytotoxic T lymphocytes. Nature (1984) 3.46
Naturally processed viral peptides recognized by cytotoxic T lymphocytes on cells chronically infected by human immunodeficiency virus type 1. J Exp Med (1994) 2.81
Origins of MIT inquiry. Nature (1991) 2.81
Characterization and use of monoclonal antibodies for isolation of phosphotyrosyl proteins from retrovirus-transformed cells and growth factor-stimulated cells. Mol Cell Biol (1983) 2.70
Limited diversity of the rearranged T-cell gamma gene. Nature (1985) 2.58
Immunoprecipitation of cell surface structures of cloned cytotoxic T lymphocytes by clone-specific antisera. Proc Natl Acad Sci U S A (1984) 2.54
A novel serine esterase expressed by cytotoxic T lymphocytes. Nature (1985) 2.43
Kinetic and affinity limits on antibodies produced during immune responses. Proc Natl Acad Sci U S A (1995) 2.41
Kinetics and affinity of reactions between an antigen-specific T cell receptor and peptide-MHC complexes. Immunity (1994) 2.39
A naturally occurring peptide recognized by alloreactive CD8+ cytotoxic T lymphocytes in association with a class I MHC protein. Cell (1992) 2.34
The relative affinity of antibodies synthesized in the secondary response. J Exp Med (1967) 2.33
Attachment of an anti-receptor antibody to non-target cells renders them susceptible to lysis by a clone of cytotoxic T lymphocytes. Proc Natl Acad Sci U S A (1984) 2.32
Amino acid sequence of the light chain of a mouse myeloma protein (MOPC-315). Biochemistry (1973) 2.30
An optimal viral peptide recognized by CD8+ T cells binds very tightly to the restricting class I major histocompatibility complex protein on intact cells but not to the purified class I protein. Proc Natl Acad Sci U S A (1991) 2.26
Preparation and characterization of antibodies specific for the 2,4,6-trinitrophenyl group. Biochemistry (1966) 2.20
Autoimmune-like antibodies to the ligand-binding sites of myeloma proteins. Proc Natl Acad Sci U S A (1971) 2.17
Myeloma proteins as tumor-specific transplantation antigens. Proc Natl Acad Sci U S A (1972) 2.09
High-affinity reactions between antigen-specific T-cell receptors and peptides associated with allogeneic and syngeneic major histocompatibility complex class I proteins. Proc Natl Acad Sci U S A (1994) 2.09
Phosphotyrosine-containing proteins isolated by affinity chromatography with antibodies to a synthetic hapten. Nature (1981) 2.08
Functional differences between memory and naive CD8 T cells. Proc Natl Acad Sci U S A (1999) 1.94
Variations in the number of peptide-MHC class I complexes required to activate cytotoxic T cell responses. J Immunol (1995) 1.91
Vesicular stomatitis virus glycoprotein is necessary for H-2-restricted lysis of infected cells by cytotoxic T lymphocytes. Proc Natl Acad Sci U S A (1978) 1.88
Serine esterase in cytolytic T lymphocytes. Nature (1986) 1.85
Secondary, tertiary, and quaternary structure of T-cell-specific immunoglobulin-like polypeptide chains. Proc Natl Acad Sci U S A (1986) 1.81
Sequential changes in the relative affinity of antibodies synthesized during the immune response. J Exp Med (1967) 1.80
Subunit structure and number of combining sites of the immunoglobulin A myeloma protein produced by mouse plasmacytoma MOPC-315. Biochemistry (1971) 1.68
Symposium on in vitro studies of the immune response. I. Variations in the immune response to a simple determinant. Bacteriol Rev (1966) 1.65
A ubiquitous protein is the source of naturally occurring peptides that are recognized by a CD8+ T-cell clone. Proc Natl Acad Sci U S A (1993) 1.63
Cognate peptides induce self-destruction of CD8+ cytolytic T lymphocytes. Proc Natl Acad Sci U S A (1990) 1.63
Dependence of lymphopenia-induced T cell proliferation on the abundance of peptide/ MHC epitopes and strength of their interaction with T cell receptors. Proc Natl Acad Sci U S A (2001) 1.61
Antibodies to idiotypes of isologous immunoglobulins. J Exp Med (1975) 1.56
Amino acid sequence of the light chain from a mouse myeloma protein with anti-hapten activity: evidence for a third type of light chain. Proc Natl Acad Sci U S A (1971) 1.52
Experimental approaches to homogenous antibody populations. Myeloma proteins with antihapten antibody activity. Fed Proc (1970) 1.51
Myeloma proteins with anti-hapten antibody activity: epsilon-2,4-dinitrophenyl lysine binding by the protein produced by mouse plasmacytoma MOPC-460. J Immunol (1969) 1.51
Calcium ion concentrations and DNA fragmentation in target cell destruction by murine cloned cytotoxic T lymphocytes. J Exp Med (1988) 1.49
The immune response to a simple antigenic determinant. Harvey Lect (1966) 1.47
Peptide antagonism and T cell receptor interactions with peptide-MHC complexes. Immunity (1998) 1.46
Heat shock fusion proteins as vehicles for antigen delivery into the major histocompatibility complex class I presentation pathway. Proc Natl Acad Sci U S A (1997) 1.46
Specificity of the immune response to the 2,4-dinitrophenyl and 2,4,6-trinitrophenyl groups. Ligand binding and fluorescence properties of cross-reacting antibodies. J Exp Med (1969) 1.44
The law of mass action governs antigen-stimulated cytolytic activity of CD8+ cytotoxic T lymphocytes. Proc Natl Acad Sci U S A (1995) 1.43
Cytotoxic T lymphocytes recognize a reconstituted class I histocompatibility antigen (HLA-A2) as an allogeneic target molecule. Proc Natl Acad Sci U S A (1990) 1.41
Effects of N alpha-tosyl-L-lysyl-chloromethylketone on the activity of cytotoxic T lymphocytes. J Immunol (1980) 1.39
Amino-acid sequence of the variable region of the heavy (alpha) chain of a mouse myeloma protein with anti-hapten activity. Proc Natl Acad Sci U S A (1974) 1.36
Recognition of immunoglobulin idiotypes by thymus-derived lymphocytes. Proc Natl Acad Sci U S A (1975) 1.33
Adenomatoid Transformation of the Glomerular Capsular Epithelium. Am J Pathol (1946) 1.33
Specificity and structure of the myeloma protein produced by mouse plasmacytoma MOPC-460. Biochemistry (1971) 1.32
Synthetic phospholipid vesicles containing a purified viral antigen and cell membrane proteins stimulate the development of cytotoxic T lymphocytes. J Exp Med (1979) 1.31
Identification of a third type of lambda light chain in mouse immunoglobulins. Proc Natl Acad Sci U S A (1981) 1.31
Resistance of cytotoxic T lymphocytes to lysis by a clone of cytotoxic T lymphocytes. Proc Natl Acad Sci U S A (1987) 1.30
Differences in antigen recognition and cytolytic activity of CD8(+) and CD8(-) T cells that express the same antigen-specific receptor. Proc Natl Acad Sci U S A (2001) 1.30
Expression of the T-cell-specific gamma gene is unnecessary in T cells recognizing class II MHC determinants. Nature (1985) 1.29
Degeneracy in the secondary immune response: stimulation of antibody formation by cross-reacting antigens. Isr J Med Sci (1969) 1.27
In vivo cytotoxic T lymphocyte elicitation by mycobacterial heat shock protein 70 fusion proteins maps to a discrete domain and is CD4(+) T cell independent. J Exp Med (2000) 1.26
Subunit interactions and their relationship to the allosteric properties of rabbit skeletal muscle phosphorylase b. Biochemistry (1968) 1.24
The natural abundance of lambda2-light chains in inbred mice. J Exp Med (1978) 1.23
Crawling movements of lymphocytes on and beneath fibroblasts in culture. Proc Natl Acad Sci U S A (1979) 1.21
Cell-bound myeloma proteins on the surface of myeloma cells: potential targets for the immune system. Proc Natl Acad Sci U S A (1972) 1.20
Affinity labeling of the heavy and light chains of a myeloma protein with anti-2,4-dinitrophenyl activity. Proc Natl Acad Sci U S A (1970) 1.20
IMPAIRMENT OF ANTIBODY RESPONSE IN PYRIDOXINE-DEFICIENT RATS. J Exp Med (1947) 1.19
Localization of affinity-labeled residues on the heavy and light chain of two myeloma proteins with anti-hapten activity. Biochemistry (1972) 1.17
Inhibition of cytotoxic T lymphocyte activity by concanavalin A. J Immunol (1982) 1.17
A proposed mechanism for the induction of cytotoxic T lymphocyte production by heat shock fusion proteins. Immunity (2000) 1.16
Learning and memory in the immune response. Cancer Res (1966) 1.16
A functional gamma gene formed from known gamma-gene segments is not necessary for antigen-specific responses of murine cytotoxic T lymphocytes. Nature (1986) 1.15
Evidence for tryptophan in the active sites of antibodies to polynitrobenzenes. Biochemistry (1967) 1.14
Resistance of cytotoxic T lymphocytes to the lytic effects of their toxic granules. J Exp Med (1987) 1.14
The strange cross-reaction of menadione (vitamin K3) and 2,4-dinitrophenyl ligands with a myeloma protein and some conventional antibodies. J Exp Med (1974) 1.13
Breaking the affinity ceiling for antibodies and T cell receptors. Proc Natl Acad Sci U S A (2000) 1.12
Quantitation of reversible binding by particle counting: hapten-antibody interaction as a model system. Proc Natl Acad Sci U S A (1992) 1.12
The site of action of N-alpha-tosyl-L-lysyl-chloromethyl-ketone (TLCK) on cloned cytotoxic T lymphocytes. J Immunol (1983) 1.11
Chromosomal locations of the murine T-cell receptor alpha-chain gene and the T-cell gamma gene. Science (1985) 1.10
Lambda chains and genes in inbred mice. Annu Rev Immunol (1985) 1.10
Heteroantibody duplexes target cells for lysis by cytotoxic T lymphocytes. Proc Natl Acad Sci U S A (1985) 1.08
Distribution of allelic allotypes among gamma-G-immunoglobulins and purified anti-hapten antibodies from the same rabbit. J Immunol (1965) 1.06
Glycosylation of the T-cell antigen-specific receptor and its potential role in lectin-mediated cytotoxicity. Proc Natl Acad Sci U S A (1986) 1.04
Lambda2 light chains in normal mouse immunoglobulins. Proc Natl Acad Sci U S A (1978) 1.03
Allorecognition of purified major histocompatibility complex glycoproteins by cytotoxic T lymphocytes. Proc Natl Acad Sci U S A (1988) 1.03
Isolation and partial characterization of concanavalin A receptors on cloned cytotoxic T lymphocytes. Proc Natl Acad Sci U S A (1984) 1.02
Perforin mRNA in primary peritoneal exudate cytotoxic T lymphocytes. J Immunol (1989) 1.02
T-cell antigens in cancer. Proc Natl Acad Sci U S A (1994) 1.01
Myeloma proteins as tumor-specific antigens. Transplant Proc (1975) 1.00
Tissue-specific expression of functionally rearranged lambda 1 Ig gene through a retrovirus vector. Science (1987) 1.00
Resistance of primary CD8+ cytotoxic T lymphocytes to lysis by cytotoxic granules from cloned T cell lines. J Immunol (1988) 0.99
Affinity labeling and cross-linking of the heavy and light chains of a myeloma protein with anti-2,4-dinitrophenyl activity. Biochemistry (1971) 0.99
Periodic loss of reactivity of a myeloma tumor with cytotoxic thymus-derived lymphocytes. Proc Natl Acad Sci U S A (1978) 0.98
Restricted association of V and J-C gene segments for mouse lambda chains. Proc Natl Acad Sci U S A (1984) 0.98
Effects of substrates and a substrate analog on the binding of 5'-adenylic acid to muscle phosphorylase a. Biochemistry (1967) 0.97
Unusual association of V, J and C regions in a mouse immunoglobulin lambda chain. Nature (1982) 0.97
Effect of variation in antibody-hapten association constant upon the biologic activity of the antibody. J Immunol (1965) 0.97
Lymphomas with cytotoxic activity. Nature (1979) 0.95
Cognate peptide-induced destruction of CD8+ cytotoxic T lymphocytes is due to fratricide. J Immunol (1993) 0.95
Differences in spectral properties and tryptophan content among rabbit anti-2,4-dinitrophenyl antibodies of the gamma G-immunologbulin class. Biochemistry (1968) 0.95