Published in J Biol Chem on April 04, 2006
Integrated analysis of metabolite and transcript levels reveals the metabolic shifts that underlie tomato fruit development and highlight regulatory aspects of metabolic network behavior. Plant Physiol (2006) 2.55
The missing step of the L-galactose pathway of ascorbate biosynthesis in plants, an L-galactose guanyltransferase, increases leaf ascorbate content. Proc Natl Acad Sci U S A (2007) 1.59
The Arabidopsis thaliana Myo-inositol 1-phosphate synthase1 gene is required for Myo-inositol synthesis and suppression of cell death. Plant Cell (2010) 1.37
Arabidopsis VTC2 encodes a GDP-L-galactose phosphorylase, the last unknown enzyme in the Smirnoff-Wheeler pathway to ascorbic acid in plants. J Biol Chem (2007) 1.33
Expression profiling of ascorbic acid-related genes during tomato fruit development and ripening and in response to stress conditions. J Exp Bot (2009) 1.32
New connections across pathways and cellular processes: industrialized mutant screening reveals novel associations between diverse phenotypes in Arabidopsis. Plant Physiol (2008) 1.24
Candidate genes and quantitative trait loci affecting fruit ascorbic acid content in three tomato populations. Plant Physiol (2007) 1.22
L-Ascorbate biosynthesis in higher plants: the role of VTC2. Trends Plant Sci (2008) 1.17
Alterations in the endogenous ascorbic acid content affect flowering time in Arabidopsis. Plant Physiol (2008) 1.14
VTC4 is a bifunctional enzyme that affects myoinositol and ascorbate biosynthesis in plants. Plant Physiol (2009) 1.13
GDP-mannose pyrophosphorylase is a genetic determinant of ammonium sensitivity in Arabidopsis thaliana. Proc Natl Acad Sci U S A (2008) 1.07
Myoinositol oxygenase controls the level of myoinositol in Arabidopsis, but does not increase ascorbic acid. Plant Physiol (2008) 1.03
A mutation in GDP-mannose pyrophosphorylase causes conditional hypersensitivity to ammonium, resulting in Arabidopsis root growth inhibition, altered ammonium metabolism, and hormone homeostasis. J Exp Bot (2009) 0.98
L-ascorbic Acid: a multifunctional molecule supporting plant growth and development. Scientifica (Cairo) (2013) 0.97
The missing link in plant histidine biosynthesis: Arabidopsis myoinositol monophosphatase-like2 encodes a functional histidinol-phosphate phosphatase. Plant Physiol (2009) 0.94
Ascorbate biosynthesis during early fruit development is the main reason for its accumulation in kiwi. PLoS One (2010) 0.94
Allelic variation in paralogs of GDP-L-galactose phosphorylase is a major determinant of vitamin C concentrations in apple fruit. Plant Physiol (2012) 0.94
Ascorbate metabolism and the developmental demand for tartaric and oxalic acids in ripening grape berries. BMC Plant Biol (2009) 0.92
Arabidopsis phosphomannose isomerase 1, but not phosphomannose isomerase 2, is essential for ascorbic acid biosynthesis. J Biol Chem (2008) 0.91
Evolution of alternative biosynthetic pathways for vitamin C following plastid acquisition in photosynthetic eukaryotes. Elife (2015) 0.90
A second GDP-L-galactose phosphorylase in arabidopsis en route to vitamin C. Covalent intermediate and substrate requirements for the conserved reaction. J Biol Chem (2008) 0.86
Manipulation of L-ascorbic acid biosynthesis pathways in Solanum lycopersicum: elevated GDP-mannose pyrophosphorylase activity enhances L-ascorbate levels in red fruit. Planta (2011) 0.85
Influence of light on ascorbate formation and metabolism in apple fruits. Planta (2009) 0.84
The pathway via D-galacturonate/L-galactonate is significant for ascorbate biosynthesis in Euglena gracilis: identification and functional characterization of aldonolactonase. J Biol Chem (2008) 0.83
Regulation of fruit ascorbic acid concentrations during ripening in high and low vitamin C tomato cultivars. BMC Plant Biol (2012) 0.82
The influence of metal stress on the availability and redox state of ascorbate, and possible interference with its cellular functions. Int J Mol Sci (2013) 0.82
Enhancement of plant metabolite fingerprinting by machine learning. Plant Physiol (2010) 0.81
Integrative Approaches to Enhance Understanding of Plant Metabolic Pathway Structure and Regulation. Plant Physiol (2015) 0.81
Increasing vitamin C content in plant foods to improve their nutritional value-successes and challenges. Nutrients (2013) 0.81
Involvement of Arabidopsis Hexokinase1 in Cell Death Mediated by Myo-Inositol Accumulation. Plant Cell (2015) 0.81
Characterization of the inositol monophosphatase gene family in Arabidopsis. Front Plant Sci (2015) 0.79
Expression and functions of myo-inositol monophosphatase family genes in seed development of Arabidopsis. J Plant Res (2010) 0.78
Completing a pathway to plant vitamin C synthesis. Proc Natl Acad Sci U S A (2007) 0.77
Role of L-ascorbate in alleviating abiotic stresses in crop plants. Bot Stud (2014) 0.77
Overexpression of the OsIMP Gene Increases the Accumulation of Inositol and Confers Enhanced Cold Tolerance in Tobacco through Modulation of the Antioxidant Enzymes' Activities. Genes (Basel) (2017) 0.76
Tartaric acid pathways in Vitis vinifera L. (cv. Ugni blanc): a comparative study of two vintages with contrasted climatic conditions. BMC Plant Biol (2016) 0.76
Recent progress on the characterization of aldonolactone oxidoreductases. Plant Physiol Biochem (2015) 0.76
Knocking Down the Expression of GMPase Gene OsVTC1-1 Decreases Salt Tolerance of Rice at Seedling and Reproductive Stages. PLoS One (2016) 0.75
Transcriptomic analysis of the biosynthesis, recycling, and distribution of ascorbic acid during leaf development in tea plant (Camellia sinensis (L.) O. Kuntze). Sci Rep (2017) 0.75
Conservation and Expression Patterns Divergence of Ascorbic Acid d-mannose/l-galactose Pathway Genes in Brassica rapa. Front Plant Sci (2016) 0.75
Characterization of the galactono-1,4-lactone dehydrogenase from pepper fruits and its modulation in the ascorbate biosynthesis. Role of nitric oxide. Redox Biol (2017) 0.75
The manipulation of gene expression and the biosynthesis of Vitamin C, E and folate in light-and dark-germination of sweet corn seeds. Sci Rep (2017) 0.75
Synthesis of customized petroleum-replica fuel molecules by targeted modification of free fatty acid pools in Escherichia coli. Proc Natl Acad Sci U S A (2013) 1.97
Two genes in Arabidopsis thaliana encoding GDP-L-galactose phosphorylase are required for ascorbate biosynthesis and seedling viability. Plant J (2007) 1.91
Analysis of the root-hair morphogenesis transcriptome reveals the molecular identity of six genes with roles in root-hair development in Arabidopsis. Plant J (2006) 1.90
Generation of reactive oxygen species by fungal NADPH oxidases is required for rice blast disease. Proc Natl Acad Sci U S A (2007) 1.87
Reactive oxygen species produced by NADPH oxidase are involved in pollen tube growth. New Phytol (2007) 1.78
Metal and redox modulation of cysteine protein function. Chem Biol (2003) 1.52
Antisense suppression of l-galactose dehydrogenase in Arabidopsis thaliana provides evidence for its role in ascorbate synthesis and reveals light modulated l-galactose synthesis. Plant J (2002) 1.50
NADPH oxidase-dependent reactive oxygen species formation required for root hair growth depends on ROP GTPase. J Exp Bot (2007) 1.41
The high light response in Arabidopsis involves ABA signaling between vascular and bundle sheath cells. Plant Cell (2009) 1.41
Tps1 regulates the pentose phosphate pathway, nitrogen metabolism and fungal virulence. EMBO J (2007) 1.35
The response of Thalassiosira pseudonana to long-term exposure to increased CO2 and decreased pH. PLoS One (2011) 1.28
Insights into the evolution of vitamin B12 auxotrophy from sequenced algal genomes. Mol Biol Evol (2011) 1.28
An NADPH-dependent genetic switch regulates plant infection by the rice blast fungus. Proc Natl Acad Sci U S A (2010) 1.19
The influence of ascorbate on anthocyanin accumulation during high light acclimation in Arabidopsis thaliana: further evidence for redox control of anthocyanin synthesis. Plant Cell Environ (2011) 1.17
Perfluorodecalin enhances in vivo confocal microscopy resolution of Arabidopsis thaliana mesophyll. New Phytol (2010) 1.17
The yeast glutaredoxins are active as glutathione peroxidases. J Biol Chem (2002) 1.16
Reactive oxygen species and nitric oxide mediate actin reorganization and programmed cell death in the self-incompatibility response of papaver. Plant Physiol (2011) 1.15
An order-disorder twin crystal of L-2-haloacid dehalogenase from Sulfolobus tokodaii. Acta Crystallogr D Biol Crystallogr (2007) 1.14
The structure of an alcohol dehydrogenase from the hyperthermophilic archaeon Aeropyrum pernix. J Mol Biol (2003) 1.12
Armadillo repeat-containing kinesins and a NIMA-related kinase are required for epidermal-cell morphogenesis in Arabidopsis. Plant J (2007) 1.11
The crystal structure of a (-) gamma-lactamase from an Aureobacterium species reveals a tetrahedral intermediate in the active site. J Mol Biol (2004) 1.05
Clearance of ingested neonicotinoid pesticide (imidacloprid) in honey bees (Apis mellifera) and bumblebees (Bombus terrestris). Pest Manag Sci (2013) 1.00
Compartmentalized calcium signaling in cilia regulates intraflagellar transport. Curr Biol (2013) 0.97
Ecophysiology of photosynthesis in bryophytes: major roles for oxygen photoreduction and non-photochemical quenching? Physiol Plant (2010) 0.96
Proline metabolism and transport in maize seedlings at low water potential. Ann Bot (2002) 0.95
Crystal structure of a thermostable old yellow enzyme from Thermus scotoductus SA-01. Biochem Biophys Res Commun (2010) 0.94
Comparison of gene expression in segregating families identifies genes and genomic regions involved in a novel adaptation, zinc hyperaccumulation. Mol Ecol (2006) 0.94
Role for PPARgamma in IL-2 inhibition in T cells by Echinacea-derived undeca-2E-ene-8,10-diynoic acid isobutylamide. Int Immunopharmacol (2009) 0.94
Biolistic delivery of Ca2+ dyes into plant and algal cells. Plant J (2006) 0.93
Controlled protein precipitation in combination with chip-based nanospray infusion mass spectrometry. An approach for metabolomics profiling of plasma. Anal Chem (2005) 0.93
Antioxidant status, peroxidase activity, and PR protein transcript levels in ascorbate-deficient Arabidopsis thaliana vtc mutants. J Exp Bot (2008) 0.92
Crystallization and preliminary X-ray diffraction studies of a fungal hydrolase from Ophiostoma novo-ulmi. Acta Crystallogr D Biol Crystallogr (2004) 0.89
A microreactor for the study of biotransformations by a cross-linked gamma-lactamase enzyme. Biotechnol J (2009) 0.89
Widespread decay of vitamin-related pathways: coincidence or consequence? Trends Genet (2013) 0.89
Proton channels in algae: reasons to be excited. Trends Plant Sci (2012) 0.86
Biochemical and structural studies of a L-haloacid dehalogenase from the thermophilic archaeon Sulfolobus tokodaii. Extremophiles (2008) 0.86
A thermostable L-aminoacylase from Thermococcus litoralis: cloning, overexpression, characterization, and applications in biotransformations. Extremophiles (2002) 0.85
The effect of acute high light and low temperature stresses on the ascorbate-glutathione cycle and superoxide dismutase activity in two Dunaliella salina strains. Physiol Plant (2009) 0.85
Lymphocytes from rheumatoid arthritis patients have elevated levels of intracellular peroxiredoxin 2, and a greater frequency of cells with exofacial peroxiredoxin 2, compared with healthy human lymphocytes. Int J Biochem Cell Biol (2012) 0.85
Vanadium containing bromoperoxidase--insights into the enzymatic mechanism using X-ray crystallography. J Inorg Biochem (2009) 0.85
The substrate specificity, enantioselectivity and structure of the (R)-selective amine : pyruvate transaminase from Nectria haematococca. FEBS J (2014) 0.82
Structural studies of Pseudomonas and Chromobacterium ω-aminotransferases provide insights into their differing substrate specificity. Acta Crystallogr D Biol Crystallogr (2013) 0.82
Seed production temperature regulation of primary dormancy occurs through control of seed coat phenylpropanoid metabolism. New Phytol (2014) 0.81
Making open data work for plant scientists. J Exp Bot (2013) 0.81
Expression of aspartyl protease and C3HC4-type RING zinc finger genes are responsive to ascorbic acid in Arabidopsis thaliana. J Exp Bot (2011) 0.81
The binding of haem and zinc in the 1.9 A X-ray structure of Escherichia coli bacterioferritin. J Biol Inorg Chem (2008) 0.80
Vitamin C booster. Nat Biotechnol (2003) 0.80
Expression analysis of the VTC2 and VTC5 genes encoding GDP-L-galactose phosphorylase, an enzyme involved in ascorbate biosynthesis, in Arabidopsis thaliana. Biosci Biotechnol Biochem (2011) 0.80
The Fasciola hepatica thioredoxin: High resolution structure reveals two oxidation states. Mol Biochem Parasitol (2008) 0.79
Synthetic metabolons for metabolic engineering. J Exp Bot (2014) 0.79
Crystallization and preliminary X-ray diffraction studies of a novel alcohol dehydrogenase from the hyperthermophilic archaeon Aeropyrum pernix. Acta Crystallogr D Biol Crystallogr (2002) 0.79
Ascorbate deficiency influences the leaf cell wall glycoproteome in Arabidopsis thaliana. Plant Cell Environ (2014) 0.78
Marine Rhodobacteraceae L-haloacid dehalogenase contains a novel His/Glu dyad that could activate the catalytic water. FEBS J (2013) 0.78
Crystallization and preliminary X-ray diffraction analysis of omega-amino acid:pyruvate transaminase from Chromobacterium violaceum. Acta Crystallogr Sect F Struct Biol Cryst Commun (2007) 0.77
Characterisation of an L-haloacid dehalogenase from the marine psychrophile Psychromonas ingrahamii with potential industrial application. Mar Biotechnol (NY) (2013) 0.77
Characterisation and biosynthesis of D-erythroascorbic acid in Phycomyces blakesleeanus. Fungal Genet Biol (2005) 0.77
A quantitative trait loci analysis of zinc hyperaccumulation in Arabidopsis halleri. New Phytol (2007) 0.77
Cloning and expression of cytosolic phosphoglycerate kinase from pea (Pisum sativum L.). J Exp Bot (2004) 0.77
Amino acid properties may be useful in predicting clinical outcome in patients with Kir6.2 neonatal diabetes. Eur J Endocrinol (2012) 0.76
Functional and structural characterisation of a viral cytochrome b5. FEBS Lett (2013) 0.76
Nuclear dynamics during the simultaneous and sustained tip growth of multiple root hairs arising from a single root epidermal cell. J Exp Bot (2006) 0.76
The use of HyPer to examine spatial and temporal changes in H2O2 in high light-exposed plants. Methods Enzymol (2013) 0.76
Crystallization and preliminary X-ray diffraction analysis of L-aminoacylase from the hyperthermophilic archaeon Thermococcus litoralis. Acta Crystallogr D Biol Crystallogr (2002) 0.75
Synthesis and characterisation of a ligand that forms a stable tetrahedral intermediate in the active site of the Aureobacterium species (-) gamma-lactamase. Org Biomol Chem (2005) 0.75