Published in Int J Parasitol on March 10, 2006
Blood-stage Plasmodium infection induces CD8+ T lymphocytes to parasite-expressed antigens, largely regulated by CD8alpha+ dendritic cells. Proc Natl Acad Sci U S A (2008) 1.73
IP-10-mediated T cell homing promotes cerebral inflammation over splenic immunity to malaria infection. PLoS Pathog (2009) 1.61
Plasmodium falciparum picks (on) EPCR. Blood (2013) 1.53
CCDC88B is a novel regulator of maturation and effector functions of T cells during pathological inflammation. J Exp Med (2014) 1.49
CD8+ T cells and IFN-γ mediate the time-dependent accumulation of infected red blood cells in deep organs during experimental cerebral malaria. PLoS One (2011) 1.47
Accumulation of Plasmodium berghei-infected red blood cells in the brain is crucial for the development of cerebral malaria in mice. Infect Immun (2010) 1.47
Neuroimmunological blood brain barrier opening in experimental cerebral malaria. PLoS Pathog (2012) 1.35
Brain microvessel cross-presentation is a hallmark of experimental cerebral malaria. EMBO Mol Med (2013) 1.28
Sequestration and tissue accumulation of human malaria parasites: can we learn anything from rodent models of malaria? PLoS Pathog (2010) 1.23
Endothelial cell protein C receptor: a multiliganded and multifunctional receptor. Blood (2014) 1.20
The CTLA-4 and PD-1/PD-L1 inhibitory pathways independently regulate host resistance to Plasmodium-induced acute immune pathology. PLoS Pathog (2012) 1.14
Cerebral malaria: mysteries at the blood-brain barrier. Virulence (2012) 1.05
Caspase-1 activation of interleukin-1β (IL-1β) and IL-18 is dispensable for induction of experimental cerebral malaria. Infect Immun (2011) 1.02
Experimental cerebral malaria pathogenesis--hemodynamics at the blood brain barrier. PLoS Pathog (2014) 0.97
Pharmacologic inhibition of CXCL10 in combination with anti-malarial therapy eliminates mortality associated with murine model of cerebral malaria. PLoS One (2013) 0.94
Heterogeneous and tissue-specific regulation of effector T cell responses by IFN-gamma during Plasmodium berghei ANKA infection. J Immunol (2011) 0.93
Hyperbaric oxygen prevents early death caused by experimental cerebral malaria. PLoS One (2008) 0.91
Platelets present antigen in the context of MHC class I. J Immunol (2012) 0.91
Atorvastatin treatment is effective when used in combination with mefloquine in an experimental cerebral malaria murine model. Malar J (2012) 0.90
Cytoadherence of Plasmodium berghei-infected red blood cells to murine brain and lung microvascular endothelial cells in vitro. Infect Immun (2013) 0.90
Protein kinase C-theta is required for development of experimental cerebral malaria. Am J Pathol (2010) 0.89
Damage to the blood-brain barrier during experimental cerebral malaria results from synergistic effects of CD8+ T cells with different specificities. Infect Immun (2014) 0.89
The role of chemokines in severe malaria: more than meets the eye. Parasitology (2013) 0.88
Both functional LTbeta receptor and TNF receptor 2 are required for the development of experimental cerebral malaria. PLoS One (2008) 0.88
Predominance of interferon-related responses in the brain during murine malaria, as identified by microarray analysis. Infect Immun (2008) 0.88
Pathogenic CD8+ T cells in experimental cerebral malaria. Semin Immunopathol (2015) 0.87
Lipoxin A₄ and 15-epi-lipoxin A₄ protect against experimental cerebral malaria by inhibiting IL-12/IFN-γ in the brain. PLoS One (2013) 0.84
IgG autoantibody to brain beta tubulin III associated with cytokine cluster-II discriminate cerebral malaria in central India. PLoS One (2009) 0.83
Perivascular Arrest of CD8+ T Cells Is a Signature of Experimental Cerebral Malaria. PLoS Pathog (2015) 0.82
Peroxisome proliferator activating receptor (PPAR) in cerebral malaria (CM): a novel target for an additional therapy. Eur J Clin Microbiol Infect Dis (2010) 0.81
High IFN-gamma and TNF production by peripheral NK cells of Colombian patients with different clinical presentation of Plasmodium falciparum. Malar J (2012) 0.79
Plasmodium attenuation: connecting the dots between early immune responses and malaria disease severity. Front Microbiol (2014) 0.79
The subcellular location of ovalbumin in Plasmodium berghei blood stages influences the magnitude of T-cell responses. Infect Immun (2014) 0.79
Identification of the Plasmodium berghei resistance locus 9 linked to survival on chromosome 9. Malar J (2013) 0.78
Phosphatidylinositol 3-Kinase γ is required for the development of experimental cerebral malaria. PLoS One (2015) 0.77
Myocardial Dysfunction: A Primary Cause of Death Due To Severe Malaria in A Plasmodium falciparum-Infected Humanized Mouse Model. Iran J Parasitol (2013) 0.76
Angiotensin II type-1 receptor (AT1R) regulates expansion, differentiation, and functional capacity of antigen-specific CD8(+) T cells. Sci Rep (2016) 0.76
Mouse ENU Mutagenesis to Understand Immunity to Infection: Methods, Selected Examples, and Perspectives. Genes (Basel) (2014) 0.76
Experimental Models of Microvascular Immunopathology: The Example of Cerebral Malaria. J Neuroinfect Dis (2014) 0.76
Cannabinoid Receptor 2 Modulates Susceptibility to Experimental Cerebral Malaria through a CCL17-dependent Mechanism. J Biol Chem (2016) 0.75
Cross-presentation of malaria antigen by brain microvessels: why CD8(+) T cells are critical for the pathogenesis of experimental cerebral malaria. EMBO Mol Med (2013) 0.75
A TCRβ Repertoire Signature Can Predict Experimental Cerebral Malaria. PLoS One (2016) 0.75
Toxoplasma gondii upregulates interleukin-12 to prevent Plasmodium berghei-induced experimental cerebral malaria. Infect Immun (2014) 0.75
Targeting Angiotensin II Type-1 Receptor (AT1R) Inhibits the Harmful Phenotype of Plasmodium-Specific CD8(+) T Cells during Blood-Stage Malaria. Front Cell Infect Microbiol (2017) 0.75
IL-33 receptor ST2 regulates the cognitive impairments associated with experimental cerebral malaria. PLoS Pathog (2017) 0.75
Young Sprague Dawley rats infected by Plasmodium berghei: A relevant experimental model to study cerebral malaria. PLoS One (2017) 0.75
Relapses of Plasmodium vivax infection usually result from activation of heterologous hypnozoites. J Infect Dis (2007) 4.35
Protection against a malaria challenge by sporozoite inoculation. N Engl J Med (2009) 4.03
Two nonrecombining sympatric forms of the human malaria parasite Plasmodium ovale occur globally. J Infect Dis (2010) 3.21
On the cytoadhesion of Plasmodium vivax-infected erythrocytes. J Infect Dis (2010) 2.91
Spurious amplification of a Plasmodium vivax small-subunit RNA gene by use of primers currently used to detect P. knowlesi. J Clin Microbiol (2009) 2.85
On the diversity of malaria parasites in African apes and the origin of Plasmodium falciparum from Bonobos. PLoS Pathog (2010) 2.60
On the pathogenic role of brain-sequestered alphabeta CD8+ T cells in experimental cerebral malaria. J Immunol (2002) 2.40
Novel point mutations in the dihydrofolate reductase gene of Plasmodium vivax: evidence for sequential selection by drug pressure. Antimicrob Agents Chemother (2003) 2.26
Efficacy and safety of artemether-lumefantrine compared with quinine in pregnant women with uncomplicated Plasmodium falciparum malaria: an open-label, randomised, non-inferiority trial. Lancet Infect Dis (2010) 2.24
A reliable ex vivo invasion assay of human reticulocytes by Plasmodium vivax. Blood (2011) 2.17
Practical PCR genotyping protocols for Plasmodium vivax using Pvcs and Pvmsp1. Malar J (2005) 2.15
Protective T cell immunity against malaria liver stage after vaccination with live sporozoites under chloroquine treatment. J Immunol (2004) 2.12
Effective and cheap removal of leukocytes and platelets from Plasmodium vivax infected blood. Malar J (2009) 2.08
The genetic diversity of Plasmodium vivax populations. Trends Parasitol (2003) 2.01
Plasmodium sporozoites trickle out of the injection site. Cell Microbiol (2007) 1.98
Invasion of host cells by malaria parasites: a tale of two protein families. Mol Microbiol (2007) 1.79
A pre-emptive strike against malaria's stealthy hepatic forms. Nat Rev Drug Discov (2009) 1.77
Plasmodium falciparum msp1, msp2 and glurp allele frequency and diversity in sub-Saharan Africa. Malar J (2011) 1.66
Molecular characterization of dihydrofolate reductase in relation to antifolate resistance in Plasmodium vivax. Mol Biochem Parasitol (2002) 1.62
Malaria in pregnant Cameroonian women: the effect of age and gravidity on submicroscopic and mixed-species infections and multiple parasite genotypes. Am J Trop Med Hyg (2005) 1.62
Towards an in vitro model of Plasmodium hypnozoites suitable for drug discovery. PLoS One (2011) 1.60
Is EPO therapy able to correct iron deficiency anaemia caused by matriptase-2 deficiency? Br J Haematol (2011) 1.55
Vaccination with live Plasmodium yoelii blood stage parasites under chloroquine cover induces cross-stage immunity against malaria liver stage. J Immunol (2008) 1.53
Molecular genotyping to distinguish between recrudescents and new infections in treatment trials of Plasmodium falciparum malaria conducted in Sub-Saharan Africa: adjustment of parasitological outcomes and assessment of genotyping effectiveness. Trop Med Int Health (2006) 1.50
A plant-derived morphinan as a novel lead compound active against malaria liver stages. PLoS Med (2006) 1.49
Environmental influence on the genetic basis of mosquito resistance to malaria parasites. Proc Biol Sci (2006) 1.48
Population structure analysis of Plasmodium vivax in areas of iran with different malaria endemicity. Am J Trop Med Hyg (2006) 1.46
Rapid species diagnosis for invasive candidiasis using mass spectrometry. PLoS One (2010) 1.44
Sterile protection against malaria is independent of immune responses to the circumsporozoite protein. PLoS One (2007) 1.41
Migrating monocytes recruited to the spleen play an important role in control of blood stage malaria. Blood (2009) 1.40
High deformability of Plasmodium vivax-infected red blood cells under microfluidic conditions. J Infect Dis (2009) 1.40
Cross-talk between the mitogen activated protein kinase and bone morphogenetic protein/hemojuvelin pathways is required for the induction of hepcidin by holotransferrin in primary mouse hepatocytes. Haematologica (2009) 1.36
Limited polymorphism in the dihydropteroate synthetase gene (dhps) of Plasmodium vivax isolates from Thailand. Antimicrob Agents Chemother (2005) 1.33
Considerations on the use of nucleic acid-based amplification for malaria parasite detection. Malar J (2011) 1.32
Early cytokine production is associated with protection from murine cerebral malaria. Infect Immun (2005) 1.32
Chloroquine resistant vivax malaria in a pregnant woman on the western border of Thailand. Malar J (2011) 1.29
Plasmodium falciparum: PCR detection and genotyping of isolates from peripheral, placental, and cord blood of pregnant Malawian women and their infants. Trans R Soc Trop Med Hyg (2002) 1.28
Circumsporozoite protein gene diversity among temperate and tropical Plasmodium vivax isolates from Iran. Trop Med Int Health (2006) 1.27
MALDI-TOF MS-based drug susceptibility testing of pathogens: the example of Candida albicans and fluconazole. Proteomics (2009) 1.26
Cryptic Plasmodium falciparum parasites in clinical P. vivax blood samples from Thailand. Trans R Soc Trop Med Hyg (2002) 1.25
CCR5 deficiency decreases susceptibility to experimental cerebral malaria. Blood (2003) 1.23
Are extensive T cell epitope polymorphisms in the Plasmodium falciparum circumsporozoite antigen, a leading sporozoite vaccine candidate, selected by immune pressure? J Immunol (2005) 1.22
Temperature shift and host cell contact up-regulate sporozoite expression of Plasmodium falciparum genes involved in hepatocyte infection. PLoS Pathog (2008) 1.19
The evolutionary history of Plasmodium vivax as inferred from mitochondrial genomes: parasite genetic diversity in the Americas. Mol Biol Evol (2013) 1.18
Hepcidin targets ferroportin for degradation in hepatocytes. Haematologica (2009) 1.17
Timing the origin of human malarias: the lemur puzzle. BMC Evol Biol (2011) 1.17
Genetic complexity of Plasmodium falciparum gametocytes isolated from the peripheral blood of treated Gambian children. Am J Trop Med Hyg (2002) 1.15
Recombinant human IFN-alpha inhibits cerebral malaria and reduces parasite burden in mice. J Immunol (2007) 1.14
Multiple genotypes of the merozoite surface proteins 1 and 2 in Plasmodium falciparum infections in a hypoendemic area in Iran. Trop Med Int Health (2005) 1.14
Inhibitory effect of TNF-α on malaria pre-erythrocytic stage development: influence of host hepatocyte/parasite combinations. PLoS One (2011) 1.12
A vaccine encoding conserved promiscuous HIV CD4 epitopes induces broad T cell responses in mice transgenic to multiple common HLA class II molecules. PLoS One (2010) 1.11
Genetic analysis of the dihydrofolate reductase-thymidylate synthase gene from geographically diverse isolates of Plasmodium malariae. Antimicrob Agents Chemother (2007) 1.10
Minimal role for the circumsporozoite protein in the induction of sterile immunity by vaccination with live rodent malaria sporozoites. Infect Immun (2010) 1.06
Performance of a histidine-rich protein 2 rapid diagnostic test, Paracheck Pf®, for detection of malaria infections in Ugandan pregnant women. Am J Trop Med Hyg (2012) 1.03
Transmission of mixed Plasmodium species and Plasmodium falciparum genotypes. Am J Trop Med Hyg (2003) 1.03
The Py235 proteins: glimpses into the versatility of a malaria multigene family. Microbes Infect (2004) 1.03
Artesunate-dapsone-proguanil treatment of falciparum malaria: genotypic determinants of therapeutic response. Trans R Soc Trop Med Hyg (2005) 1.02
A role for immune responses against non-CS components in the cross-species protection induced by immunization with irradiated malaria sporozoites. PLoS One (2009) 1.01
The Plasmodium sporozoite survives RTS,S vaccination. Trends Parasitol (2005) 0.98
Oncostatin M is a potent inducer of hepcidin, the iron regulatory hormone. FASEB J (2010) 0.98
A new real-time PCR for the detection of Plasmodium ovale wallikeri. PLoS One (2012) 0.97
Transmission of Plasmodium vivax in south-western Uganda: report of three cases in pregnant women. PLoS One (2011) 0.97
Iron-deficiency anemia from matriptase-2 inactivation is dependent on the presence of functional Bmp6. Blood (2010) 0.97
Cerebral malaria: in praise of epistemes. Trends Parasitol (2010) 0.96
Vaccination against malaria with live parasites. Expert Rev Vaccines (2006) 0.96
Species-specific inhibition of cerebral malaria in mice coinfected with Plasmodium spp. Infect Immun (2005) 0.95
Resistance and susceptibility to filarial infection with Litomosoides sigmodontis are associated with early differences in parasite development and in localized immune reactions. Infect Immun (2003) 0.95
Microsatellite genotyping of Plasmodium vivax infections and their relapses in pregnant and non-pregnant patients on the Thai-Myanmar border. Malar J (2013) 0.93
Human ex vivo studies on asexual Plasmodium vivax: the best way forward. Int J Parasitol (2012) 0.92
Increased early local immune responses and altered worm development in high-dose infections of mice susceptible to the filaria Litomosoides sigmodontis. Med Microbiol Immunol (2004) 0.91
The suitability of P. falciparum merozoite surface proteins 1 and 2 as genetic markers for in vivo drug trials in Yemen. PLoS One (2013) 0.90