Published in Parasitology on December 13, 2013
Pathogenesis of cerebral malaria--inflammation and cytoadherence. Front Cell Infect Microbiol (2014) 1.06
Placental Responses to Changes in the Maternal Environment Determine Fetal Growth. Front Physiol (2016) 0.88
Experimental Cerebral Malaria Spreads along the Rostral Migratory Stream. PLoS Pathog (2016) 0.79
From within host dynamics to the epidemiology of infectious disease: Scientific overview and challenges. Math Biosci (2015) 0.78
Excessive Pro-Inflammatory Serum Cytokine Concentrations in Virulent Canine Babesiosis. PLoS One (2016) 0.78
Cytokine network in adults with falciparum Malaria and HIV-1: increased IL-8 and IP-10 levels are associated with disease severity. PLoS One (2014) 0.78
Reduction of experimental cerebral malaria and its related proinflammatory responses by the novel liposome-based β-methasone nanodrug. Biomed Res Int (2014) 0.76
Patterns of inflammatory responses and parasite tolerance vary with malaria transmission intensity. Malar J (2017) 0.75
Expanding the antimalarial toolkit: Targeting host-parasite interactions. J Exp Med (2016) 0.75
Inhibition of placental mTOR signaling provides a link between placental malaria and reduced birthweight. BMC Med (2017) 0.75
IL-33 receptor ST2 regulates the cognitive impairments associated with experimental cerebral malaria. PLoS Pathog (2017) 0.75
Fibroblasts: The Unknown Sentinels Eliciting Immune Responses Against Microorganisms. Eur J Microbiol Immunol (Bp) (2017) 0.75
Cytokines and Chemokines in Cerebral Malaria Pathogenesis. Front Cell Infect Microbiol (2017) 0.75
Global malaria mortality between 1980 and 2010: a systematic analysis. Lancet (2012) 17.62
Indicators of life-threatening malaria in African children. N Engl J Med (1995) 13.17
Chemokines--chemotactic cytokines that mediate inflammation. N Engl J Med (1998) 12.80
Epidemiology and burden of malaria in pregnancy. Lancet Infect Dis (2007) 10.66
The pathogenic basis of malaria. Nature (2002) 10.44
Chemokines. Blood (1997) 9.80
The burden of malaria in pregnancy in malaria-endemic areas. Am J Trop Med Hyg (2001) 8.60
Differentiating the pathologies of cerebral malaria by postmortem parasite counts. Nat Med (2004) 7.42
Monocyte-mediated defense against microbial pathogens. Annu Rev Immunol (2008) 7.21
Tumor necrosis factor (cachectin) as an essential mediator in murine cerebral malaria. Science (1987) 7.01
Chemokines in innate and adaptive host defense: basic chemokinese grammar for immune cells. Annu Rev Immunol (2004) 5.07
The role of chemokine receptors in primary, effector, and memory immune responses. Annu Rev Immunol (2000) 4.78
Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses. Immunol Today (1998) 4.21
MCP-1 and IL-8 trigger firm adhesion of monocytes to vascular endothelium under flow conditions. Nature (1999) 4.19
Orchestrating the orchestrators: chemokines in control of T cell traffic. Nat Immunol (2008) 4.17
Migratory properties of naive, effector, and memory CD8(+) T cells. J Exp Med (2001) 4.17
Immunological processes in malaria pathogenesis. Nat Rev Immunol (2005) 3.80
Epidemiology, malaria and pregnancy. Am J Trop Med Hyg (1984) 3.32
Chemokines: multiple levels of leukocyte migration control. Trends Immunol (2004) 3.32
Cytokines: accelerators and brakes in the pathogenesis of cerebral malaria. Trends Immunol (2003) 3.18
Monoclonal antibody against interferon gamma can prevent experimental cerebral malaria and its associated overproduction of tumor necrosis factor. Proc Natl Acad Sci U S A (1989) 3.03
Human interferon-inducible protein 10 is a potent inhibitor of angiogenesis in vivo. J Exp Med (1995) 2.99
T-cell homing specificity and plasticity: new concepts and future challenges. Trends Immunol (2006) 2.94
Rules of chemokine receptor association with T cell polarization in vivo. J Clin Invest (2001) 2.87
Central role of the spleen in malaria parasite clearance. J Infect Dis (2002) 2.80
L3T4+ T lymphocytes play a major role in the pathogenesis of murine cerebral malaria. J Immunol (1986) 2.79
Placental monocyte infiltrates in response to Plasmodium falciparum malaria infection and their association with adverse pregnancy outcomes. Am J Trop Med Hyg (2003) 2.76
Platelet accumulation in brain microvessels in fatal pediatric cerebral malaria. J Infect Dis (2003) 2.70
The IP-10 chemokine binds to a specific cell surface heparan sulfate site shared with platelet factor 4 and inhibits endothelial cell proliferation. J Exp Med (1995) 2.68
Endothelial cell binding of NAP-1/IL-8: role in neutrophil emigration. Immunol Today (1992) 2.61
An ultrastructural study of the brain in fatal Plasmodium falciparum malaria. Am J Trop Med Hyg (2003) 2.47
On the pathogenic role of brain-sequestered alphabeta CD8+ T cells in experimental cerebral malaria. J Immunol (2002) 2.40
The pathophysiology of malaria. Adv Parasitol (1992) 2.33
Perforin-dependent brain-infiltrating cytotoxic CD8+ T lymphocytes mediate experimental cerebral malaria pathogenesis. J Immunol (2003) 2.22
Chemokine receptor CXCR3 and its ligands CXCL9 and CXCL10 are required for the development of murine cerebral malaria. Proc Natl Acad Sci U S A (2008) 2.08
Participation of lymphocyte subpopulations in the pathogenesis of experimental murine cerebral malaria. J Immunol (1996) 2.07
Massive chronic intervillositis of the placenta associated with malaria infection. Am J Surg Pathol (1998) 2.05
Plasma IP-10, apoptotic and angiogenic factors associated with fatal cerebral malaria in India. Malar J (2008) 2.00
Cerebrospinal fluid and serum biomarkers of cerebral malaria mortality in Ghanaian children. Malar J (2007) 1.97
Proteoglycans on endothelial cells present adhesion-inducing cytokines to leukocytes. Immunol Today (1993) 1.94
Vascular clogging, mononuclear cell margination, and enhanced vascular permeability in the pathogenesis of human cerebral malaria. Am J Trop Med Hyg (1994) 1.91
Locally up-regulated lymphotoxin alpha, not systemic tumor necrosis factor alpha, is the principle mediator of murine cerebral malaria. J Exp Med (2002) 1.86
Malaria in splenectomized patients: report of four cases and review. Clin Infect Dis (1993) 1.85
Placental malaria is associated with cell-mediated inflammatory responses with selective absence of natural killer cells. J Infect Dis (2001) 1.84
Cell cycle-dependent expression of CXC chemokine receptor 3 by endothelial cells mediates angiostatic activity. J Clin Invest (2001) 1.84
Low levels of RANTES are associated with mortality in children with cerebral malaria. J Infect Dis (2006) 1.79
International Union of Pharmacology. XXX. Update on chemokine receptor nomenclature. Pharmacol Rev (2002) 1.77
Blood-stage Plasmodium infection induces CD8+ T lymphocytes to parasite-expressed antigens, largely regulated by CD8alpha+ dendritic cells. Proc Natl Acad Sci U S A (2008) 1.73
Cerebrospinal fluid cytokine levels and cognitive impairment in cerebral malaria. Am J Trop Med Hyg (2008) 1.69
NK cells stimulate recruitment of CXCR3+ T cells to the brain during Plasmodium berghei-mediated cerebral malaria. J Immunol (2007) 1.69
Placental tumor necrosis factor alpha but not gamma interferon is associated with placental malaria and low birth weight in Malawian women. Infect Immun (2003) 1.68
The effect of a monoclonal antibody to tumor necrosis factor on survival from childhood cerebral malaria. J Infect Dis (1996) 1.62
IP-10-mediated T cell homing promotes cerebral inflammation over splenic immunity to malaria infection. PLoS Pathog (2009) 1.61
Changes in the levels of chemokines and cytokines in the placentas of women with Plasmodium falciparum malaria. J Infect Dis (2003) 1.60
TNF-induced microvascular pathology: active role for platelets and importance of the LFA-1/ICAM-1 interaction. Eur Cytokine Netw (1994) 1.56
Host response to malaria during pregnancy: placental monocyte recruitment is associated with elevated beta chemokine expression. J Immunol (2003) 1.55
Regulation of murine cerebral malaria pathogenesis by CD1d-restricted NKT cells and the natural killer complex. Immunity (2003) 1.54
Acquisition of selectin binding and peripheral homing properties by CD4(+) and CD8(+) T cells. J Exp Med (1999) 1.47
Plasmodium falciparum-infected erythrocytes induce NF-kappaB regulated inflammatory pathways in human cerebral endothelium. Blood (2009) 1.46
Pathogenic T cells in cerebral malaria. Int J Parasitol (2006) 1.45
Chemokine gene expression during fatal murine cerebral malaria and protection due to CXCR3 deficiency. J Immunol (2008) 1.42
Reversible suppression of bone marrow response to erythropoietin in Plasmodium falciparum malaria. Br J Haematol (1997) 1.41
Migrating monocytes recruited to the spleen play an important role in control of blood stage malaria. Blood (2009) 1.40
Assessment of chemokine receptor expression by human Th1 and Th2 cells in vitro and in vivo. J Leukoc Biol (1999) 1.40
Immunopathological changes in human cerebral malaria. Clin Neuropathol (1993) 1.40
Severe malarial anemia of low parasite burden in rodent models results from accelerated clearance of uninfected erythrocytes. Blood (2005) 1.39
Differential regulation of beta-chemokines in children with Plasmodium falciparum malaria. Infect Immun (2005) 1.37
The human materno-foetal relationship in malaria: I. Identification of pigment and parasites in the placenta. Trans R Soc Trop Med Hyg (1980) 1.36
Platelet factor 4 mediates inflammation in experimental cerebral malaria. Cell Host Microbe (2008) 1.34
IFN-γ-producing CD4+ T cells promote experimental cerebral malaria by modulating CD8+ T cell accumulation within the brain. J Immunol (2012) 1.34
Cytokine and chemokine responses in a cerebral malaria-susceptible or -resistant strain of mice to Plasmodium berghei ANKA infection: early chemokine expression in the brain. Int Immunol (2003) 1.26
Novel lymphocyte-specific CC chemokines and their receptors. J Leukoc Biol (1997) 1.25
The cerebral-malaria-associated expression of RANTES, CCR3 and CCR5 in post-mortem tissue samples. Ann Trop Med Parasitol (2004) 1.25
Pregnancy outcome and placenta pathology in Plasmodium berghei ANKA infected mice reproduce the pathogenesis of severe malaria in pregnant women. PLoS One (2008) 1.24
CCR5 deficiency decreases susceptibility to experimental cerebral malaria. Blood (2003) 1.23
Suppression of RANTES in children with Plasmodium falciparum malaria. Haematologica (2006) 1.22
CXCR3 determines strain susceptibility to murine cerebral malaria by mediating T lymphocyte migration toward IFN-gamma-induced chemokines. Eur J Immunol (2008) 1.20
Genome-wide expression analysis of placental malaria reveals features of lymphoid neogenesis during chronic infection. J Immunol (2007) 1.18
Correlation between enhanced vascular permeability, up-regulation of cellular adhesion molecules and monocyte adhesion to the endothelium in the retina during the development of fatal murine cerebral malaria. Am J Pathol (1996) 1.17
Transcriptional profiling reveals suppressed erythropoiesis, up-regulated glycolysis, and interferon-associated responses in murine malaria. J Infect Dis (2004) 1.14
Cerebral malaria -- a neurovascular pathology with many riddles still to be solved. Curr Neurovasc Res (2004) 1.14
Elevated serum levels of IL-1ra in children with Plasmodium falciparum malaria are associated with increased severity of disease. Cytokine (2008) 1.12
Serum concentrations of MIP-1 alpha and interleukin-8 in patients suffering from acute Plasmodium falciparum malaria. Clin Immunol Immunopathol (1995) 1.12
Circulating plasma receptors for tumour necrosis factor in Malawian children with severe falciparum malaria. Cytokine (1993) 1.09
Immunologic activation of human syncytiotrophoblast by Plasmodium falciparum. Malar J (2008) 1.08
Erythrocyte survival in severe falciparum malaria. Acta Trop (1991) 1.08
The natural killer complex regulates severe malarial pathogenesis and influences acquired immune responses to Plasmodium berghei ANKA. Infect Immun (2005) 1.07
Levels of macrophage inflammatory protein 1 alpha (MIP-1 alpha) and MIP-1 beta in intervillous blood plasma samples from women with placental malaria and human immunodeficiency virus infection. Clin Diagn Lab Immunol (2003) 1.06
Altered phenotype and gene transcription in endothelial cells, induced by Plasmodium falciparum-infected red blood cells: pathogenic or protective? Int J Parasitol (2007) 1.05
Inflammatory responses associated with the induction of cerebral malaria: lessons from experimental murine models. PLoS Pathog (2012) 1.03
CXCL4 and CXCL10 predict risk of fatal cerebral malaria. Dis Markers (2011) 1.00
Differential requirements for an intact spleen in induction and expression of B-cell-dependent immunity to Plasmodium chabaudi AS. Infect Immun (1994) 1.00
Proinflammatory and regulatory cytokines and chemokines in infants with uncomplicated and severe Plasmodium falciparum malaria. Clin Exp Immunol (2011) 0.98
Direct activation of human endothelial cells by Plasmodium falciparum-infected erythrocytes. Infect Immun (2005) 0.98
Pharmacologic inhibition of CXCL10 in combination with anti-malarial therapy eliminates mortality associated with murine model of cerebral malaria. PLoS One (2013) 0.94
Gammadelta T cells but not NK cells are essential for cell-mediated immunity against Plasmodium chabaudi malaria. Infect Immun (2010) 0.93
Biomarkers of Plasmodium falciparum infection during pregnancy in women living in northeastern Tanzania. PLoS One (2012) 0.93
Chemokine receptor CCR2 is not essential for the development of experimental cerebral malaria. Infect Immun (2003) 0.93
Plasmodium yoelii 17XL infection up-regulates RANTES, CCR1, CCR3 and CCR5 expression, and induces ultrastructural changes in the cerebellum. Malar J (2005) 0.93
Platelet factor 4 regulation of monocyte KLF4 in experimental cerebral malaria. PLoS One (2010) 0.91