Published in Antimicrob Agents Chemother on August 06, 2007
How can we identify parasite genes that underlie antimalarial drug resistance? Pharmacogenomics (2011) 1.44
Natural infection of Plasmodium brasilianum in humans: Man and monkey share quartan malaria parasites in the Venezuelan Amazon. EBioMedicine (2015) 1.15
Effect of transmission setting and mixed species infections on clinical measures of malaria in Malawi. PLoS One (2008) 1.06
In vivo and in vitro efficacy of chloroquine against Plasmodium malariae and P. ovale in Papua, Indonesia. Antimicrob Agents Chemother (2010) 1.02
Comparative population structure of Plasmodium malariae and Plasmodium falciparum under different transmission settings in Malawi. Malar J (2011) 0.94
Molecular characterization of misidentified Plasmodium ovale imported cases in Singapore. Malar J (2015) 0.87
Reduced impact of pyrimethamine drug pressure on Plasmodium malariae dihydrofolate reductase gene. Antimicrob Agents Chemother (2011) 0.87
Accurate and sensitive detection of Plasmodium species in humans by use of the dihydrofolate reductase-thymidylate synthase linker region. J Clin Microbiol (2010) 0.85
Genetic variability of Plasmodium malariae dihydropteroate synthase (dhps) in four Asian countries. PLoS One (2014) 0.81
Computational analysis of binding between malarial dihydrofolate reductases and anti-folates. Malar J (2010) 0.80
Plasmodium malariae Prevalence and csp Gene Diversity, Kenya, 2014 and 2015. Emerg Infect Dis (2017) 0.75
Plasmodium malariae and Plasmodium ovale infections in the China-Myanmar border area. Malar J (2016) 0.75
Evidence of triple mutant Pfdhps ISGNGA haplotype in Plasmodium falciparum isolates from North-east India: An analysis of sulfadoxine resistant haplotype selection. Genom Data (2016) 0.75
High sensitivity of detection of human malaria parasites by the use of nested polymerase chain reaction. Mol Biochem Parasitol (1993) 17.06
Phylogenies from molecular sequences: inference and reliability. Annu Rev Genet (1988) 15.73
A large focus of naturally acquired Plasmodium knowlesi infections in human beings. Lancet (2004) 12.21
Mixed-species malaria infections in humans. Trends Parasitol (2004) 6.01
Naturally acquired Plasmodium knowlesi malaria in human, Thailand. Emerg Infect Dis (2004) 5.58
Mutations in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase and epidemiologic patterns of pyrimethamine-sulfadoxine use and resistance. J Infect Dis (1997) 4.66
Plasmodium falciparum antimalarial drug susceptibility on the north-western border of Thailand during five years of extensive use of artesunate-mefloquine. Trans R Soc Trop Med Hyg (2000) 4.63
Amino acid changes linked to pyrimethamine resistance in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum. Proc Natl Acad Sci U S A (1988) 4.58
Phylogeny of the malarial genus Plasmodium, derived from rRNA gene sequences. Proc Natl Acad Sci U S A (1994) 4.50
Molecular basis of differential resistance to cycloguanil and pyrimethamine in Plasmodium falciparum malaria. Proc Natl Acad Sci U S A (1990) 3.98
Diagnosis of resistance to chloroquine by Plasmodium vivax: timing of recurrence and whole blood chloroquine levels. Am J Trop Med Hyg (1997) 3.61
Therapeutic responses to different antimalarial drugs in vivax malaria. Antimicrob Agents Chemother (2000) 3.46
The importance of sensitive detection of malaria parasites in the human and insect hosts in epidemiological studies, as shown by the analysis of field samples from Guinea Bissau. Trans R Soc Trop Med Hyg (1994) 3.46
Nested PCR analysis of Plasmodium parasites. Methods Mol Med (2002) 3.19
Plasmodium malariae infection in an asymptomatic 74-year-old Greek woman with splenomegaly. N Engl J Med (1998) 3.13
Evolutionary origin of human and primate malarias: evidence from the circumsporozoite protein gene. Mol Biol Evol (1995) 2.93
Association of genetic mutations in Plasmodium vivax dhfr with resistance to sulfadoxine-pyrimethamine: geographical and clinical correlates. Antimicrob Agents Chemother (2001) 2.40
Novel point mutations in the dihydrofolate reductase gene of Plasmodium vivax: evidence for sequential selection by drug pressure. Antimicrob Agents Chemother (2003) 2.26
The evolution of drug-resistant malaria: the role of drug elimination half-life. Philos Trans R Soc Lond B Biol Sci (2002) 2.20
The co-existence of Plasmodium: sidelights from falciparum and vivax malaria in Thailand. Trends Parasitol (2004) 2.16
Sequence variations in the Plasmodium vivax dihydrofolate reductase-thymidylate synthase gene and their relationship with pyrimethamine resistance. Mol Biochem Parasitol (1998) 2.08
Point mutations in the dihydrofolate reductase-thymidylate synthase gene as the molecular basis for pyrimethamine resistance in Plasmodium falciparum. Mol Biochem Parasitol (1989) 1.87
A bifunctional thymidylate synthetase-dihydrofolate reductase in protozoa. Mol Biochem Parasitol (1984) 1.71
Therapeutic responses to antimalarial and antibacterial drugs in vivax malaria. Acta Trop (2004) 1.58
Phylogenetic relationship among the malaria parasites based on small subunit rRNA gene sequences: monophyletic nature of the human malaria parasite, Plasmodium falciparum. Mol Phylogenet Evol (1996) 1.56
Sequence variation in the small-subunit rRNA gene of Plasmodium malariae and prevalence of isolates with the variant sequence in Sichuan, China. J Clin Microbiol (1998) 1.49
In vitro efficacy of antimalarial drugs against Plasmodium vivax on the western border of Thailand. Am J Trop Med Hyg (2004) 1.43
High prevalence of Plamodium malariae infections in a Brazilian Amazon endemic area (Apiacás-Mato Grosso State) as detected by polymerase chain reaction. Acta Trop (2004) 1.38
Analysis of the Plasmodium vivax dihydrofolate reductase-thymidylate synthase gene sequence. Gene (1998) 1.37
Monkeys of the rainforest in French Guiana are natural reservoirs for P. brasilianum/P. malariae malaria. Parasitology (2000) 1.37
Chloroquine-resistant Plasmodium malariae in south Sumatra, Indonesia. Lancet (2002) 1.18
Survey of resistance to chloroquine of falciparum and vivax malaria in Palawan, The Philippines. Trans R Soc Trop Med Hyg (1996) 1.10
Resistance of Plasmodium malariae to pyrimethamine (daraprim). Am J Trop Med Hyg (1957) 1.00
Genetic variation of the dihydrofolate reductase gene in Plasmodium vivax in Snoul, northeastern Cambodia. Acta Trop (2004) 0.97
In vitro sensitivity of Plasmodium falciparum to sulfadoxine and pyrimethamine. Southeast Asian J Trop Med Public Health (1985) 0.84
In vitro mefloquine resistance of Plasmodium falciparum isolated from the Burmese border region of Thailand. Southeast Asian J Trop Med Public Health (1987) 0.83
Artemisinin resistance in Plasmodium falciparum malaria. N Engl J Med (2009) 33.25
High-throughput sequencing provides insights into genome variation and evolution in Salmonella Typhi. Nat Genet (2008) 19.97
Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia. Nat Med (2006) 14.21
Typhoid fever. N Engl J Med (2002) 12.96
Spread of artemisinin resistance in Plasmodium falciparum malaria. N Engl J Med (2014) 11.87
Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal study. Lancet (2012) 11.82
Vivax malaria: neglected and not benign. Am J Trop Med Hyg (2007) 10.16
Dexamethasone for the treatment of tuberculous meningitis in adolescents and adults. N Engl J Med (2004) 10.14
WHO, the Global Fund, and medical malpractice in malaria treatment. Lancet (2004) 9.27
Complete genomes of two clinical Staphylococcus aureus strains: evidence for the rapid evolution of virulence and drug resistance. Proc Natl Acad Sci U S A (2004) 8.95
Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial. Lancet (2010) 8.52
Effect of artemether-lumefantrine policy and improved vector control on malaria burden in KwaZulu-Natal, South Africa. PLoS Med (2005) 8.36
How clonal is Staphylococcus aureus? J Bacteriol (2003) 7.97
Artemisinin-resistant Plasmodium falciparum in Pursat province, western Cambodia: a parasite clearance rate study. Lancet Infect Dis (2012) 6.94
Melioidosis: insights into the pathogenicity of Burkholderia pseudomallei. Nat Rev Microbiol (2006) 6.34
Artemisinin resistance: current status and scenarios for containment. Nat Rev Microbiol (2010) 6.28
A major genome region underlying artemisinin resistance in malaria. Science (2012) 6.25
Mixed-species malaria infections in humans. Trends Parasitol (2004) 6.01
Changes in the treatment responses to artesunate-mefloquine on the northwestern border of Thailand during 13 years of continuous deployment. PLoS One (2009) 5.81
Standardizing the measurement of parasite clearance in falciparum malaria: the parasite clearance estimator. Malar J (2011) 5.65
The murine cerebral malaria phenomenon. Trends Parasitol (2009) 5.62
Hemofiltration and peritoneal dialysis in infection-associated acute renal failure in Vietnam. N Engl J Med (2002) 5.24
Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia. Nat Genet (2013) 5.22
Increasing incidence of human melioidosis in Northeast Thailand. Am J Trop Med Hyg (2010) 5.10
Evolutionary history of Salmonella typhi. Science (2006) 5.00
Estimation of the total parasite biomass in acute falciparum malaria from plasma PfHRP2. PLoS Med (2005) 4.65
Virulent combinations of adhesin and toxin genes in natural populations of Staphylococcus aureus. Infect Immun (2002) 4.62
Artemisinin-based combination treatment of falciparum malaria. Am J Trop Med Hyg (2007) 4.58
Intrahost modeling of artemisinin resistance in Plasmodium falciparum. Proc Natl Acad Sci U S A (2010) 4.50
Comparison of three fluid solutions for resuscitation in dengue shock syndrome. N Engl J Med (2005) 4.47
Manslaughter by fake artesunate in Asia--will Africa be next? PLoS Med (2006) 4.46
Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing. Nature (2012) 4.37
Relapses of Plasmodium vivax infection usually result from activation of heterologous hypnozoites. J Infect Dis (2007) 4.35
Access to artemisinin combination therapy for malaria in remote areas of Cambodia. Malar J (2008) 4.33
Genome-wide and fine-resolution association analysis of malaria in West Africa. Nat Genet (2009) 4.30
In vivo parasitological measures of artemisinin susceptibility. J Infect Dis (2010) 4.25
The last man standing is the most resistant: eliminating artemisinin-resistant malaria in Cambodia. Malar J (2009) 4.25
Molecular and pharmacological determinants of the therapeutic response to artemether-lumefantrine in multidrug-resistant Plasmodium falciparum malaria. Clin Infect Dis (2006) 4.14
Combination antifungal therapies for HIV-associated cryptococcal meningitis: a randomised trial. Lancet (2004) 4.14
Genetic loci associated with delayed clearance of Plasmodium falciparum following artemisinin treatment in Southeast Asia. Proc Natl Acad Sci U S A (2012) 4.10
Early origin and recent expansion of Plasmodium falciparum. Science (2003) 4.07
Protection against a malaria challenge by sporozoite inoculation. N Engl J Med (2009) 4.03
Counterfeit anti-infective drugs. Lancet Infect Dis (2006) 3.91
Efficacy and effectiveness of dihydroartemisinin-piperaquine versus artesunate-mefloquine in falciparum malaria: an open-label randomised comparison. Lancet (2006) 3.90
Rickettsial infections and fever, Vientiane, Laos. Emerg Infect Dis (2006) 3.87
Deployment of early diagnosis and mefloquine-artesunate treatment of falciparum malaria in Thailand: the Tak Malaria Initiative. PLoS Med (2006) 3.83
High heritability of malaria parasite clearance rate indicates a genetic basis for artemisinin resistance in western Cambodia. J Infect Dis (2010) 3.81
The influence of host and bacterial genotype on the development of disseminated disease with Mycobacterium tuberculosis. PLoS Pathog (2008) 3.79
Sensitive and inexpensive molecular test for falciparum malaria: detecting Plasmodium falciparum DNA directly from heat-treated blood by loop-mediated isothermal amplification. Clin Chem (2005) 3.75
Dihydroartemisinin-piperaquine against multidrug-resistant Plasmodium falciparum malaria in Vietnam: randomised clinical trial. Lancet (2004) 3.72
The WHO dengue classification and case definitions: time for a reassessment. Lancet (2006) 3.69
A selective sweep driven by pyrimethamine treatment in southeast asian malaria parasites. Mol Biol Evol (2003) 3.67
Reduced susceptibility of Plasmodium falciparum to artesunate in southern Myanmar. PLoS One (2013) 3.66
Prophylactic and therapeutic efficacy of human monoclonal antibodies against H5N1 influenza. PLoS Med (2007) 3.63
Adjunctive Dexamethasone in HIV-Associated Cryptococcal Meningitis. N Engl J Med (2016) 3.59
Human SNP links differential outcomes in inflammatory and infectious disease to a FOXO3-regulated pathway. Cell (2013) 3.49