Published in J Biol Chem on April 10, 2006
The human keratins: biology and pathology. Histochem Cell Biol (2008) 5.13
Toward unraveling the complexity of simple epithelial keratins in human disease. J Clin Invest (2009) 2.34
Structure and functions of keratin proteins in simple, stratified, keratinized and cornified epithelia. J Anat (2009) 2.21
Gastrointestinal differentiation marker Cytokeratin 20 is regulated by homeobox gene CDX1. Proc Natl Acad Sci U S A (2009) 1.20
p38 MAP kinase and MAPKAP kinases MK2/3 cooperatively phosphorylate epithelial keratins. J Biol Chem (2010) 0.90
Seven kinds of intermediate filament networks in the cytoplasm of polarized cells: structure and function. Acta Histochem Cytochem (2010) 0.89
Type I keratin 17 protein is phosphorylated on serine 44 by p90 ribosomal protein S6 kinase 1 (RSK1) in a growth- and stress-dependent fashion. J Biol Chem (2011) 0.87
Human colonic crypts in culture: segregation of immunochemical markers in normal versus adenoma-derived. Lab Invest (2013) 0.86
Early transcriptional response in the jejunum of germ-free piglets after oral infection with virulent rotavirus. Arch Virol (2008) 0.80
Identification of phosphorylation-induced changes in vimentin intermediate filaments by site-directed spin labeling and electron paramagnetic resonance. Biochemistry (2008) 0.79
Role of p53 in Anticancer Drug Treatment- and Radiation-Induced Injury in Normal Small Intestine. Cancer Biol Med (2012) 0.77
Phosphorylation and Reorganization of Keratin Networks: Implications for Carcinogenesis and Epithelial Mesenchymal Transition. Biomol Ther (Seoul) (2015) 0.76
An immunohistochemical study on the expression of sex steroid receptors, Ki-67 and cytokeratins 7 and 20 in feline endometrial adenocarcinomas. BMC Vet Res (2015) 0.75
Intermediate Filaments at the Junction of Mechanotransduction, Migration, and Development. Front Cell Dev Biol (2017) 0.75
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia. Nature (2011) 11.44
WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development. Cell (2005) 8.86
The site-specific installation of methyl-lysine analogs into recombinant histones. Cell (2007) 4.22
Global sequencing of proteolytic cleavage sites in apoptosis by specific labeling of protein N termini. Cell (2008) 4.00
Recommendations from the 2008 International Summit on Proteomics Data Release and Sharing Policy: the Amsterdam principles. J Proteome Res (2009) 3.77
Reporting protein identification data: the next generation of guidelines. Mol Cell Proteomics (2006) 3.50
An essential role for 14-3-3 proteins in brassinosteroid signal transduction in Arabidopsis. Dev Cell (2007) 3.46
The PSI-MOD community standard for representation of protein modification data. Nat Biotechnol (2008) 3.38
Widespread protein aggregation as an inherent part of aging in C. elegans. PLoS Biol (2010) 3.36
New consensus nomenclature for mammalian keratins. J Cell Biol (2006) 3.27
BSKs mediate signal transduction from the receptor kinase BRI1 in Arabidopsis. Science (2008) 3.04
'Hard' and 'soft' principles defining the structure, function and regulation of keratin intermediate filaments. Curr Opin Cell Biol (2002) 3.00
Cancer stem cell definitions and terminology: the devil is in the details. Nat Rev Cancer (2012) 2.76
Brassinosteroid signal transduction from cell-surface receptor kinases to nuclear transcription factors. Nat Cell Biol (2009) 2.76
Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species. PLoS Biol (2009) 2.67
O-linked N-acetylglucosamine proteomics of postsynaptic density preparations using lectin weak affinity chromatography and mass spectrometry. Mol Cell Proteomics (2006) 2.67
From Mallory to Mallory-Denk bodies: what, how and why? Exp Cell Res (2007) 2.61
Comprehensive identification of phosphorylation sites in postsynaptic density preparations. Mol Cell Proteomics (2006) 2.51
SIRT6 stabilizes DNA-dependent protein kinase at chromatin for DNA double-strand break repair. Aging (Albany NY) (2009) 2.50
A semisynthetic epitope for kinase substrates. Nat Methods (2007) 2.40
LBR and lamin A/C sequentially tether peripheral heterochromatin and inversely regulate differentiation. Cell (2013) 2.38
Targeted peptide measurements in biology and medicine: best practices for mass spectrometry-based assay development using a fit-for-purpose approach. Mol Cell Proteomics (2014) 2.37
PP2A activates brassinosteroid-responsive gene expression and plant growth by dephosphorylating BZR1. Nat Cell Biol (2011) 2.28
Panhematin provides a therapeutic benefit in experimental pancreatitis. Gut (2010) 2.23
Quantitative analysis of synaptic phosphorylation and protein expression. Mol Cell Proteomics (2007) 2.23
An unbiased cell morphology-based screen for new, biologically active small molecules. PLoS Biol (2005) 2.11
High STAT5 levels mediate imatinib resistance and indicate disease progression in chronic myeloid leukemia. Blood (2011) 2.08
A transmembrane accessory subunit that modulates kainate-type glutamate receptors. Neuron (2009) 2.07
A Raf-induced allosteric transition of KSR stimulates phosphorylation of MEK. Nature (2011) 2.07
CD73 (ecto-5'-nucleotidase) hepatocyte levels differ across mouse strains and contribute to mallory-denk body formation. Hepatology (2013) 2.04
Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse. Mol Cell Proteomics (2012) 2.03
Mutations in the gene encoding the lamin B receptor produce an altered nuclear morphology in granulocytes (Pelger-Huët anomaly). Nat Genet (2002) 1.99
Underrepresentation of underrepresented minorities in academic medicine: the need to enhance the pipeline and the pipe. Gastroenterology (2009) 1.91
Cellular integrity plus: organelle-related and protein-targeting functions of intermediate filaments. Trends Cell Biol (2005) 1.89
Sphingosylphosphorylcholine regulates keratin network architecture and visco-elastic properties of human cancer cells. Nat Cell Biol (2003) 1.84
A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain. Nature (2011) 1.84
The mammalian retromer regulates transcytosis of the polymeric immunoglobulin receptor. Nat Cell Biol (2004) 1.80
Conserved segments 1A and 2B of the intermediate filament dimer: their atomic structures and role in filament assembly. EMBO J (2002) 1.73
Energy determinants GAPDH and NDPK act as genetic modifiers for hepatocyte inclusion formation. J Cell Biol (2011) 1.72
Promiscuous aggregate-based inhibitors promote enzyme unfolding. J Med Chem (2009) 1.68
A disease- and phosphorylation-related nonmechanical function for keratin 8. J Cell Biol (2006) 1.68
Three mechanisms assemble central nervous system nodes of Ranvier. Neuron (2013) 1.68
Extracellular transglutaminase 2 is catalytically inactive, but is transiently activated upon tissue injury. PLoS One (2008) 1.67
A combinatorial code for the interaction of alpha-synuclein with membranes. J Biol Chem (2005) 1.60
Vimentin organization modulates the formation of lamellipodia. Mol Biol Cell (2011) 1.60
Epidemiology of alcohol-related liver and pancreatic disease in the United States. Arch Intern Med (2008) 1.59
A progeria mutation reveals functions for lamin A in nuclear assembly, architecture, and chromosome organization. Proc Natl Acad Sci U S A (2009) 1.58
Signaling to transcription networks in the neuronal retrograde injury response. Sci Signal (2010) 1.57
Western blots versus selected reaction monitoring assays: time to turn the tables? Mol Cell Proteomics (2013) 1.57
Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variant. Nat Struct Mol Biol (2010) 1.57
Gene expression profiling reveals stromal genes expressed in common between Barrett's esophagus and adenocarcinoma. Gastroenterology (2006) 1.54
Mass spectrometric analysis of protein mixtures at low levels using cleavable 13C-isotope-coded affinity tag and multidimensional chromatography. Mol Cell Proteomics (2003) 1.53
Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells. Proc Natl Acad Sci U S A (2011) 1.53
Pkh-kinases control eisosome assembly and organization. EMBO J (2007) 1.52
Histone acetylation and deacetylation: identification of acetylation and methylation sites of HeLa histone H4 by mass spectrometry. Mol Cell Proteomics (2002) 1.52
Targeting aldehyde dehydrogenase 2: new therapeutic opportunities. Physiol Rev (2014) 1.51
Improving software performance for peptide electron transfer dissociation data analysis by implementation of charge state- and sequence-dependent scoring. Mol Cell Proteomics (2010) 1.50
Mycobacterium tuberculosis CYP125A1, a steroid C27 monooxygenase that detoxifies intracellularly generated cholest-4-en-3-one. Mol Microbiol (2010) 1.49
ADAM22, a Kv1 channel-interacting protein, recruits membrane-associated guanylate kinases to juxtaparanodes of myelinated axons. J Neurosci (2010) 1.47
A proteomics study of brassinosteroid response in Arabidopsis. Mol Cell Proteomics (2007) 1.46
The CDG1 kinase mediates brassinosteroid signal transduction from BRI1 receptor kinase to BSU1 phosphatase and GSK3-like kinase BIN2. Mol Cell (2011) 1.44
Studying simple epithelial keratins in cells and tissues. Methods Cell Biol (2004) 1.43
Proteomics studies of brassinosteroid signal transduction using prefractionation and two-dimensional DIGE. Mol Cell Proteomics (2008) 1.43
Keratin 8/18 breakdown and reorganization during apoptosis. Exp Cell Res (2004) 1.42
The biology of desmin filaments: how do mutations affect their structure, assembly, and organisation? J Struct Biol (2004) 1.42
Crystal structure of the human lamin A coil 2B dimer: implications for the head-to-tail association of nuclear lamins. J Mol Biol (2004) 1.42
Molecular architecture of intermediate filaments. Bioessays (2003) 1.40
Nuclear envelope composition determines the ability of neutrophil-type cells to passage through micron-scale constrictions. J Biol Chem (2013) 1.40
Keratin-8-deficient mice develop chronic spontaneous Th2 colitis amenable to antibiotic treatment. J Cell Sci (2005) 1.39
MS-viewer: a web-based spectral viewer for proteomics results. Mol Cell Proteomics (2014) 1.38
Towards a molecular description of intermediate filament structure and assembly. Exp Cell Res (2007) 1.38
Keratin 8 phosphorylation by protein kinase C delta regulates shear stress-mediated disassembly of keratin intermediate filaments in alveolar epithelial cells. J Biol Chem (2005) 1.38
Nestin promotes the phosphorylation-dependent disassembly of vimentin intermediate filaments during mitosis. Mol Biol Cell (2003) 1.38
Mapping post-translational modifications of the histone variant MacroH2A1 using tandem mass spectrometry. Mol Cell Proteomics (2005) 1.38
Deciphering networks of protein interactions at the nuclear pore complex. Mol Cell Proteomics (2002) 1.37
Keratins let liver live: Mutations predispose to liver disease and crosslinking generates Mallory-Denk bodies. Hepatology (2007) 1.37
Global kinetic analysis of proteolysis via quantitative targeted proteomics. Proc Natl Acad Sci U S A (2012) 1.36
Towards an integrated understanding of the structure and mechanics of the cell nucleus. Bioessays (2008) 1.35
The DegraBase: a database of proteolysis in healthy and apoptotic human cells. Mol Cell Proteomics (2012) 1.34
Absence of keratin 19 in mice causes skeletal myopathy with mitochondrial and sarcolemmal reorganization. J Cell Sci (2007) 1.34
Reperfusion-induced translocation of deltaPKC to cardiac mitochondria prevents pyruvate dehydrogenase reactivation. Circ Res (2005) 1.34
A shared molecular mechanism underlies the human rasopathies Legius syndrome and Neurofibromatosis-1. Genes Dev (2012) 1.33
Molecular and biophysical characterization of assembly-starter units of human vimentin. J Mol Biol (2004) 1.33
Keratin binding to 14-3-3 proteins modulates keratin filaments and hepatocyte mitotic progression. Proc Natl Acad Sci U S A (2002) 1.32
The 3A protein from multiple picornaviruses utilizes the golgi adaptor protein ACBD3 to recruit PI4KIIIβ. J Virol (2012) 1.32
Molecular constituents of neuronal AMPA receptors. J Cell Biol (2005) 1.31
Hemin-activated macrophages home to the pancreas and protect from acute pancreatitis via heme oxygenase-1 induction. J Clin Invest (2005) 1.31
A data processing pipeline for mammalian proteome dynamics studies using stable isotope metabolic labeling. Mol Cell Proteomics (2011) 1.31
Severe muscle disease-causing desmin mutations interfere with in vitro filament assembly at distinct stages. Proc Natl Acad Sci U S A (2005) 1.30
Origins of elasticity in intermediate filament networks. Phys Rev Lett (2010) 1.30
Quantitative analysis of both protein expression and serine / threonine post-translational modifications through stable isotope labeling with dithiothreitol. Proteomics (2005) 1.30
Unraveling the interface of signal recognition particle and its receptor by using chemical cross-linking and tandem mass spectrometry. Proc Natl Acad Sci U S A (2004) 1.30
Modification site localization scoring integrated into a search engine. Mol Cell Proteomics (2011) 1.29