Published in Exp Cell Res on April 12, 2007
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Structure and functions of keratin proteins in simple, stratified, keratinized and cornified epithelia. J Anat (2009) 2.21
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A family of intermediate filament-like proteins is sequentially assembled into the cytoskeleton of Toxoplasma gondii. Cell Microbiol (2011) 1.50
Post-translational modifications of intermediate filament proteins: mechanisms and functions. Nat Rev Mol Cell Biol (2014) 1.50
Hierarchical structure controls nanomechanical properties of vimentin intermediate filaments. PLoS One (2009) 1.49
Intermediate filament-like proteins in bacteria and a cytoskeletal function in Streptomyces. Mol Microbiol (2008) 1.37
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The tektin family of microtubule-stabilizing proteins. Genome Biol (2008) 1.30
Intermediate filaments exchange subunits along their length and elongate by end-to-end annealing. J Cell Biol (2009) 1.20
Myopathic lamin mutations impair nuclear stability in cells and tissue and disrupt nucleo-cytoskeletal coupling. Hum Mol Genet (2013) 1.17
Head-head interaction characterizes the relaxed state of Limulus muscle myosin filaments. J Mol Biol (2008) 1.16
Novel interactors and a role for supervillin in early cytokinesis. Cytoskeleton (Hoboken) (2010) 1.10
Inroads into the structure and function of intermediate filament networks. J Struct Biol (2011) 1.09
Contribution of the cytoskeleton to the compressive properties and recovery behavior of single cells. Biophys J (2009) 1.03
Intermediate filaments in smooth muscle. Am J Physiol Cell Physiol (2008) 1.01
Identification of genes differentially expressed in myogenin knock-down bovine muscle satellite cells during differentiation through RNA sequencing analysis. PLoS One (2014) 0.96
Quantitative interactome analysis reveals a chemoresistant edgotype. Nat Commun (2015) 0.96
Involvement of the cytoskeletal elements in articular cartilage homeostasis and pathology. Int J Exp Pathol (2009) 0.96
Isomin: a novel cytoplasmic intermediate filament protein from an arthropod species. BMC Biol (2011) 0.91
Metallothionein as a clonable high-density marker for cryo-electron microscopy. J Struct Biol (2011) 0.90
Site-directed spin labeling and electron paramagnetic resonance determination of vimentin head domain structure. J Biol Chem (2010) 0.89
Alexander disease causing mutations in the C-terminal domain of GFAP are deleterious both to assembly and network formation with the potential to both activate caspase 3 and decrease cell viability. Exp Cell Res (2011) 0.87
Phosphorylation of a novel cytoskeletal protein (RsmP) regulates rod-shaped morphology in Corynebacterium glutamicum. J Biol Chem (2010) 0.86
Unique amino acid signatures that are evolutionarily conserved distinguish simple-type, epidermal and hair keratins. J Cell Sci (2012) 0.84
Head and rod 1 interactions in vimentin: identification of contact sites, structure, and changes with phosphorylation using site-directed spin labeling and electron paramagnetic resonance. J Biol Chem (2008) 0.84
Structure and dynamics of human vimentin intermediate filament dimer and tetramer in explicit and implicit solvent models. J Mol Model (2010) 0.83
Evidence for partial epithelial-to-mesenchymal transition (pEMT) and recruitment of motile blastoderm edge cells during avian epiboly. Dev Dyn (2011) 0.81
The desmin coil 1B mutation K190A impairs nebulin Z-disc assembly and destabilizes actin thin filaments. J Cell Sci (2011) 0.81
Real-time analysis of epithelial-mesenchymal transition using fluorescent single-domain antibodies. Sci Rep (2015) 0.80
Severing and end-to-end annealing of neurofilaments in neurons. Proc Natl Acad Sci U S A (2013) 0.80
Keratin 76 is required for tight junction function and maintenance of the skin barrier. PLoS Genet (2014) 0.80
Analysis of skeletal muscle function in the C57BL6/SV129 syncoilin knockout mouse. Mamm Genome (2008) 0.80
Cryo-transmission electron microscopy structure of a gigadalton peptide fiber of de novo design. Proc Natl Acad Sci U S A (2012) 0.79
Plasticity of intermediate filament subunits. PLoS One (2010) 0.78
The Cardiomyopathy Lamin A/C D192G Mutation Disrupts Whole-Cell Biomechanics in Cardiomyocytes as Measured by Atomic Force Microscopy Loading-Unloading Curve Analysis. Sci Rep (2015) 0.78
Keratin network modifications lead to the mechanical stiffening of the hair follicle fiber. Proc Natl Acad Sci U S A (2016) 0.78
Complete Structure of an Epithelial Keratin Dimer: Implications for Intermediate Filament Assembly. PLoS One (2015) 0.78
Cross-immunoreactivity between the LH1 antibody and cytokeratin epitopes in the differentiating epidermis of embryos of the grass snake Natrix natrix L. during the end stages of embryogenesis. Protoplasma (2011) 0.76
Identification and characterization of a bovine sperm acrosomal matrix protein and its mechanism of interaction with acrosomal hydrolases. Mol Cell Biochem (2015) 0.76
Identification and cytoprotective function of a novel nestin isoform, Nes-S, in dorsal root ganglia neurons. J Biol Chem (2013) 0.76
Role of Intermediate Filaments in Vesicular Traffic. Cells (2016) 0.75
ngs (notochord granular surface) gene encodes a novel type of intermediate filament family protein essential for notochord maintenance in zebrafish. J Biol Chem (2012) 0.75
Structural Dynamics of the Vimentin Coiled-coil Contact Regions Involved in Filament Assembly as Revealed by Hydrogen-Deuterium Exchange. J Biol Chem (2016) 0.75
Compartmentation of Mitochondrial and Oxidative Metabolism in Growing Hair Follicles: A Ring of Fire. J Invest Dermatol (2017) 0.75
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia. Nature (2011) 11.44
Intermediate filaments: molecular structure, assembly mechanism, and integration into functionally distinct intracellular Scaffolds. Annu Rev Biochem (2004) 3.30
Intermediate filaments: from cell architecture to nanomechanics. Nat Rev Mol Cell Biol (2007) 2.95
The nanomechanical signature of breast cancer. Nat Nanotechnol (2012) 2.89
The nuclear pore complex: nucleocytoplasmic transport and beyond. Nat Rev Mol Cell Biol (2003) 2.77
Cancer stem cell definitions and terminology: the devil is in the details. Nat Rev Cancer (2012) 2.76
Rational design of small-molecule inhibitors of the LEDGF/p75-integrase interaction and HIV replication. Nat Chem Biol (2010) 2.48
Modular self-assembly of a Y-shaped multiprotein complex from seven nucleoporins. EMBO J (2002) 2.47
Nanomechanical basis of selective gating by the nuclear pore complex. Science (2007) 2.44
LBR and lamin A/C sequentially tether peripheral heterochromatin and inversely regulate differentiation. Cell (2013) 2.38
Analysis of alpha-helical coiled coils with the program TWISTER reveals a structural mechanism for stutter compensation. J Struct Biol (2002) 2.28
Dynamic elastic modulus of porcine articular cartilage determined at two different levels of tissue organization by indentation-type atomic force microscopy. Biophys J (2004) 2.20
Early detection of aging cartilage and osteoarthritis in mice and patient samples using atomic force microscopy. Nat Nanotechnol (2009) 2.19
Flexible phenylalanine-glycine nucleoporins as entropic barriers to nucleocytoplasmic transport. Proc Natl Acad Sci U S A (2006) 2.16
Lamin A/C-dependent localization of Nesprin-2, a giant scaffolder at the nuclear envelope. Mol Biol Cell (2005) 2.15
Multiple assembly pathways underlie amyloid-beta fibril polymorphisms. J Mol Biol (2005) 2.14
High STAT5 levels mediate imatinib resistance and indicate disease progression in chronic myeloid leukemia. Blood (2011) 2.08
Cryo-electron tomography provides novel insights into nuclear pore architecture: implications for nucleocytoplasmic transport. J Mol Biol (2003) 2.05
Mutations in the gene encoding the lamin B receptor produce an altered nuclear morphology in granulocytes (Pelger-Huët anomaly). Nat Genet (2002) 1.99
Hrr25-dependent phosphorylation state regulates organization of the pre-40S subunit. Nature (2006) 1.95
Intermediate filaments: primary determinants of cell architecture and plasticity. J Clin Invest (2009) 1.88
Exploring the 3D molecular architecture of Escherichia coli type 1 pili. J Mol Biol (2002) 1.81
Domain-specific antibodies reveal multiple-site topology of Nup153 within the nuclear pore complex. J Struct Biol (2002) 1.76
Conserved segments 1A and 2B of the intermediate filament dimer: their atomic structures and role in filament assembly. EMBO J (2002) 1.73
Restrictive cardiomyopathy with atrioventricular conduction block resulting from a desmin mutation. Int J Cardiol (2006) 1.62
The S. cerevisiae HtrA-like protein Nma111p is a nuclear serine protease that mediates yeast apoptosis. J Cell Sci (2004) 1.62
Vimentin organization modulates the formation of lamellipodia. Mol Biol Cell (2011) 1.60
A progeria mutation reveals functions for lamin A in nuclear assembly, architecture, and chromosome organization. Proc Natl Acad Sci U S A (2009) 1.58
The VASP tetramerization domain is a right-handed coiled coil based on a 15-residue repeat. Proc Natl Acad Sci U S A (2004) 1.57
The parallel superpleated beta-structure as a model for amyloid fibrils of human amylin. J Mol Biol (2005) 1.56
The nuclear pore complex: a jack of all trades? Trends Biochem Sci (2004) 1.55
A nonadjuvanted polypeptide nanoparticle vaccine confers long-lasting protection against rodent malaria. J Immunol (2009) 1.50
Actin in the nucleus: what form and what for? J Struct Biol (2002) 1.46
Towards reconciling structure and function in the nuclear pore complex. Histochem Cell Biol (2008) 1.45
Full-length rat amylin forms fibrils following substitution of single residues from human amylin. J Mol Biol (2003) 1.44
The biology of desmin filaments: how do mutations affect their structure, assembly, and organisation? J Struct Biol (2004) 1.42
Crystal structure of the human lamin A coil 2B dimer: implications for the head-to-tail association of nuclear lamins. J Mol Biol (2004) 1.42
Molecular architecture of intermediate filaments. Bioessays (2003) 1.40
Nuclear envelope composition determines the ability of neutrophil-type cells to passage through micron-scale constrictions. J Biol Chem (2013) 1.40
Nestin promotes the phosphorylation-dependent disassembly of vimentin intermediate filaments during mitosis. Mol Biol Cell (2003) 1.38
Nuclear actin extends, with no contraction in sight. Mol Biol Cell (2005) 1.36
Towards an integrated understanding of the structure and mechanics of the cell nucleus. Bioessays (2008) 1.35
Protective antibody and CD8+ T-cell responses to the Plasmodium falciparum circumsporozoite protein induced by a nanoparticle vaccine. PLoS One (2012) 1.35
A pre-ribosome with a tadpole-like structure functions in ATP-dependent maturation of 60S subunits. Mol Cell (2004) 1.34
Molecular and biophysical characterization of assembly-starter units of human vimentin. J Mol Biol (2004) 1.33
Human amylin oligomer growth and fibril elongation define two distinct phases in amyloid formation. J Biol Chem (2004) 1.33
Structure-based design of peptides that self-assemble into regular polyhedral nanoparticles. Nanomedicine (2006) 1.32
Severe muscle disease-causing desmin mutations interfere with in vitro filament assembly at distinct stages. Proc Natl Acad Sci U S A (2005) 1.30
Origins of elasticity in intermediate filament networks. Phys Rev Lett (2010) 1.30
Tracking down the different forms of nuclear actin. Trends Cell Biol (2006) 1.29
Functional complexity of intermediate filament cytoskeletons: from structure to assembly to gene ablation. Int Rev Cytol (2003) 1.28
Tensile properties of single desmin intermediate filaments. Biophys J (2008) 1.28
The LINC-less granulocyte nucleus. Eur J Cell Biol (2008) 1.26
Micro- and nanomechanical analysis of articular cartilage by indentation-type atomic force microscopy: validation with a gel-microfiber composite. Biophys J (2010) 1.26
Sac3 is an mRNA export factor that localizes to cytoplasmic fibrils of nuclear pore complex. Mol Biol Cell (2003) 1.26
A quantitative kinetic model for the in vitro assembly of intermediate filaments from tetrameric vimentin. J Biol Chem (2007) 1.25
The highly conserved nuclear lamin Ig-fold binds to PCNA: its role in DNA replication. J Cell Biol (2008) 1.24
Conspicuous involvement of desmin tail mutations in diverse cardiac and skeletal myopathies. Hum Mutat (2007) 1.24
Isolation, characterization, and in vitro assembly of intermediate filaments. Methods Cell Biol (2004) 1.23
Multisite binding of a general anesthetic to the prokaryotic pentameric Erwinia chrysanthemi ligand-gated ion channel (ELIC). J Biol Chem (2013) 1.22
Mutations at the mouse ichthyosis locus are within the lamin B receptor gene: a single gene model for human Pelger-Huët anomaly. Hum Mol Genet (2003) 1.22
Self-assembly of human MxA GTPase into highly ordered dynamin-like oligomers. J Biol Chem (2002) 1.21
Myomesin is a molecular spring with adaptable elasticity. J Mol Biol (2005) 1.21
Structural analysis of a metazoan nuclear pore complex reveals a fused concentric ring architecture. J Mol Biol (2009) 1.19
Peptide nanoparticles as novel immunogens: design and analysis of a prototypic severe acute respiratory syndrome vaccine. Chem Biol Drug Des (2009) 1.18
Crystal structures of a cysteine-modified mutant in loop D of acetylcholine-binding protein. J Biol Chem (2010) 1.18
Myopathic lamin mutations impair nuclear stability in cells and tissue and disrupt nucleo-cytoskeletal coupling. Hum Mol Genet (2013) 1.17
Laminopathic mutations interfere with the assembly, localization, and dynamics of nuclear lamins. Proc Natl Acad Sci U S A (2007) 1.17
The nuclear lamina. Both a structural framework and a platform for genome organization. FEBS J (2007) 1.17
Desminopathies: pathology and mechanisms. Acta Neuropathol (2012) 1.17
Divalent cations crosslink vimentin intermediate filament tail domains to regulate network mechanics. J Mol Biol (2010) 1.17
The dynamic properties of intermediate filaments during organelle transport. J Cell Sci (2009) 1.17
The core of tau-paired helical filaments studied by scanning transmission electron microscopy and limited proteolysis. Biochemistry (2006) 1.16
Ca2+ -dependent interaction of S100A1 with F1-ATPase leads to an increased ATP content in cardiomyocytes. Mol Cell Biol (2007) 1.16
The nanomechanical properties of rat fibroblasts are modulated by interfering with the vimentin intermediate filament system. J Struct Biol (2011) 1.14
Localization of uroplakin Ia, the urothelial receptor for bacterial adhesin FimH, on the six inner domains of the 16 nm urothelial plaque particle. J Mol Biol (2002) 1.14