Published in ACS Nano on December 22, 2009
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High yield, scalable and remotely drug-loaded neutrophil-derived extracellular vesicles (EVs) for anti-inflammation therapy. Biomaterials (2017) 0.76
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Silica-coated magnetic nanoparticles impair proteasome activity and increase the formation of cytoplasmic inclusion bodies in vitro. Sci Rep (2016) 0.75
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Viral attachment induces rapid recruitment of an innate immune sensor (TRIM5α) to the plasma membrane. J Innate Immun (2013) 0.75
Cytosolic co-delivery of miRNA-34a and docetaxel with core-shell nanocarriers via caveolae-mediated pathway for the treatment of metastatic breast cancer. Sci Rep (2017) 0.75
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Cell membrane-derived nanoparticles: emerging clinical opportunities for targeted drug delivery. Nanomedicine (Lond) (2017) 0.75
Imaging intracellular fluorescent proteins at nanometer resolution. Science (2006) 38.97
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Caveolar endocytosis of simian virus 40 reveals a new two-step vesicular-transport pathway to the ER. Nat Cell Biol (2001) 8.93
The use of nanocrystals in biological detection. Nat Biotechnol (2004) 8.34
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In vivo biodistribution and highly efficient tumour targeting of carbon nanotubes in mice. Nat Nanotechnol (2006) 6.93
The multiple faces of caveolae. Nat Rev Mol Cell Biol (2007) 6.85
STED microscopy reveals that synaptotagmin remains clustered after synaptic vesicle exocytosis. Nature (2006) 6.54
Nanometer-localized multiple single-molecule fluorescence microscopy. Proc Natl Acad Sci U S A (2004) 5.98
Bruchpilot promotes active zone assembly, Ca2+ channel clustering, and vesicle release. Science (2006) 5.39
Beyond Rayleigh's criterion: a resolution measure with application to single-molecule microscopy. Proc Natl Acad Sci U S A (2006) 5.07
Luminescent quantum dots for multiplexed biological detection and imaging. Curr Opin Biotechnol (2002) 4.93
Live dynamic imaging of caveolae pumping targeted antibody rapidly and specifically across endothelium in the lung. Nat Biotechnol (2007) 3.54
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Kinase-regulated quantal assemblies and kiss-and-run recycling of caveolae. Nature (2005) 2.75
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Role of Src-induced dynamin-2 phosphorylation in caveolae-mediated endocytosis in endothelial cells. J Biol Chem (2004) 1.94
Quantitative analysis of albumin uptake and transport in the rat microvessel endothelial monolayer. Am J Physiol Lung Cell Mol Physiol (2003) 1.81
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Secrets of caveolae- and lipid raft-mediated endocytosis revealed by mammalian viruses. Biochim Biophys Acta (2005) 1.43
Targeting endothelium and its dynamic caveolae for tissue-specific transcytosis in vivo: a pathway to overcome cell barriers to drug and gene delivery. Proc Natl Acad Sci U S A (2002) 1.43
Albumin uptake and transcytosis in endothelial cells in vivo induced by albumin-binding protein. Am J Physiol Lung Cell Mol Physiol (2001) 1.32
Albumin mediates the transcytosis of myeloperoxidase by means of caveolae in endothelial cells. Proc Natl Acad Sci U S A (2004) 1.20
Signaling mechanisms regulating endothelial permeability. Physiol Rev (2006) 7.63
Lipid emulsion is superior to vasopressin in a rodent model of resuscitation from toxin-induced cardiac arrest. Crit Care Med (2009) 3.56
Regulation of endothelial junctional permeability. Ann N Y Acad Sci (2008) 3.39
NF-kappa B activation as a pathological mechanism of septic shock and inflammation. Am J Physiol Lung Cell Mol Physiol (2006) 3.15
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Regulation of endothelial permeability via paracellular and transcellular transport pathways. Annu Rev Physiol (2010) 2.86
Reactive oxygen species in inflammation and tissue injury. Antioxid Redox Signal (2013) 2.59
NADPH oxidase-dependent signaling in endothelial cells: role in physiology and pathophysiology. Antioxid Redox Signal (2009) 2.29
Role of TRPM2 channel in mediating H2O2-induced Ca2+ entry and endothelial hyperpermeability. Circ Res (2007) 2.24
Caveolin regulation of endothelial function. Am J Physiol Lung Cell Mol Physiol (2003) 2.22
TLR4 signaling induces TLR2 expression in endothelial cells via neutrophil NADPH oxidase. J Clin Invest (2003) 2.16
Toll-like receptor-4 (TLR4) signaling augments chemokine-induced neutrophil migration by modulating cell surface expression of chemokine receptors. Nat Med (2003) 2.14
Persistent eNOS activation secondary to caveolin-1 deficiency induces pulmonary hypertension in mice and humans through PKG nitration. J Clin Invest (2009) 2.02
RhoGDI-1 modulation of the activity of monomeric RhoGTPase RhoA regulates endothelial barrier function in mouse lungs. Circ Res (2007) 1.99
Neutrophil caveolin-1 expression contributes to mechanism of lung inflammation and injury. Am J Physiol Lung Cell Mol Physiol (2007) 1.97
Role of Src-induced dynamin-2 phosphorylation in caveolae-mediated endocytosis in endothelial cells. J Biol Chem (2004) 1.94
Novel mechanism of endothelial nitric oxide synthase activation mediated by caveolae internalization in endothelial cells. Circ Res (2006) 1.92
Caveolin-1 regulates store-operated Ca2+ influx by binding of its scaffolding domain to transient receptor potential channel-1 in endothelial cells. Mol Pharmacol (2006) 1.92
Toll-like receptor 4 mediates neutrophil sequestration and lung injury induced by endotoxin and hyperinflation. Crit Care Med (2010) 1.87
Caveolin-1 regulates NF-kappaB activation and lung inflammatory response to sepsis induced by lipopolysaccharide. J Immunol (2006) 1.86
Activation of sphingosine kinase-1 reverses the increase in lung vascular permeability through sphingosine-1-phosphate receptor signaling in endothelial cells. Circ Res (2008) 1.85
Protease-activated receptor-3 (PAR3) regulates PAR1 signaling by receptor dimerization. Proc Natl Acad Sci U S A (2007) 1.81
Quantitative analysis of albumin uptake and transport in the rat microvessel endothelial monolayer. Am J Physiol Lung Cell Mol Physiol (2003) 1.81
Caveolin-1 scaffold domain interacts with TRPC1 and IP3R3 to regulate Ca2+ store release-induced Ca2+ entry in endothelial cells. Am J Physiol Cell Physiol (2008) 1.80
Suppression of RhoA activity by focal adhesion kinase-induced activation of p190RhoGAP: role in regulation of endothelial permeability. J Biol Chem (2005) 1.74
Protein kinase C-delta (PKC-delta ) is activated by type I interferons and mediates phosphorylation of Stat1 on serine 727. J Biol Chem (2002) 1.72
Endothelial cell-restricted disruption of FoxM1 impairs endothelial repair following LPS-induced vascular injury. J Clin Invest (2006) 1.71
Ca2+ signaling, TRP channels, and endothelial permeability. Microcirculation (2006) 1.70
Lipopolysaccharide stimulates platelet secretion and potentiates platelet aggregation via TLR4/MyD88 and the cGMP-dependent protein kinase pathway. J Immunol (2009) 1.70
Role of Ca2+ signaling in the regulation of endothelial permeability. Vascul Pharmacol (2002) 1.69
Dual regulation of endothelial junctional permeability. Sci STKE (2007) 1.67
Localized RhoA GTPase activity regulates dynamics of endothelial monolayer integrity. Cardiovasc Res (2013) 1.63
Two waves of platelet secretion induced by thromboxane A2 receptor and a critical role for phosphoinositide 3-kinases. J Biol Chem (2003) 1.63
Intercellular adhesion molecule-1-dependent neutrophil adhesion to endothelial cells induces caveolae-mediated pulmonary vascular hyperpermeability. Circ Res (2008) 1.63
Role of NADPH oxidase in the mechanism of lung neutrophil sequestration and microvessel injury induced by Gram-negative sepsis: studies in p47phox-/- and gp91phox-/- mice. J Immunol (2002) 1.60
Phosphorylation of caveolin-1 regulates oxidant-induced pulmonary vascular permeability via paracellular and transcellular pathways. Circ Res (2009) 1.57
Increased pulmonary vascular resistance and defective pulmonary artery filling in caveolin-1-/- mice. Am J Physiol Lung Cell Mol Physiol (2008) 1.56
The redox-sensitive cation channel TRPM2 modulates phagocyte ROS production and inflammation. Nat Immunol (2011) 1.55
Constitutive eNOS-derived nitric oxide is a determinant of endothelial junctional integrity. Am J Physiol Lung Cell Mol Physiol (2005) 1.54
Protein kinase Calpha phosphorylates the TRPC1 channel and regulates store-operated Ca2+ entry in endothelial cells. J Biol Chem (2004) 1.53
Molecular determinants of endothelial transcytosis and their role in endothelial permeability. Am J Physiol Lung Cell Mol Physiol (2007) 1.53
Sphingosine 1-phosphate-induced mobilization of intracellular Ca2+ mediates rac activation and adherens junction assembly in endothelial cells. J Biol Chem (2005) 1.52
Nonmuscle myosin light-chain kinase mediates neutrophil transmigration in sepsis-induced lung inflammation by activating beta2 integrins. Nat Immunol (2008) 1.51
Protein kinase Calpha-induced p115RhoGEF phosphorylation signals endothelial cytoskeletal rearrangement. J Biol Chem (2003) 1.50
Phosphatidylinositol 3-kinase gamma signaling through protein kinase Czeta induces NADPH oxidase-mediated oxidant generation and NF-kappaB activation in endothelial cells. J Biol Chem (2006) 1.49
siRNA-induced caveolin-1 knockdown in mice increases lung vascular permeability via the junctional pathway. Am J Physiol Lung Cell Mol Physiol (2005) 1.48
PKCzeta regulates TNF-alpha-induced activation of NADPH oxidase in endothelial cells. Circ Res (2002) 1.46
Angiopoietin-1 opposes VEGF-induced increase in endothelial permeability by inhibiting TRPC1-dependent Ca2 influx. Circ Res (2005) 1.44
Galphaq-TRPC6-mediated Ca2+ entry induces RhoA activation and resultant endothelial cell shape change in response to thrombin. J Biol Chem (2006) 1.44
Tumor necrosis factor-alpha induces early-onset endothelial adhesivity by protein kinase Czeta-dependent activation of intercellular adhesion molecule-1. Circ Res (2003) 1.44
Bidirectional regulation of neutrophil migration by mitogen-activated protein kinases. Nat Immunol (2012) 1.43
RhoA interaction with inositol 1,4,5-trisphosphate receptor and transient receptor potential channel-1 regulates Ca2+ entry. Role in signaling increased endothelial permeability. J Biol Chem (2003) 1.43
Tumor necrosis factor-alpha-induced TRPC1 expression amplifies store-operated Ca2+ influx and endothelial permeability. Am J Physiol Lung Cell Mol Physiol (2004) 1.41
G protein-dependent basal and evoked endothelial cell vWF secretion. Blood (2013) 1.39
RNA interference targeting transforming growth factor-beta type II receptor suppresses ocular inflammation and fibrosis. Mol Vis (2004) 1.36
Galpha(q) and Gbetagamma regulate PAR-1 signaling of thrombin-induced NF-kappaB activation and ICAM-1 transcription in endothelial cells. Circ Res (2002) 1.36
Tyrosine phosphorylation-dependence of caveolae-mediated endocytosis. J Cell Mol Med (2008) 1.32
Cdc42 regulates the restoration of endothelial barrier function. Circ Res (2003) 1.31
Gbetagamma activation of Src induces caveolae-mediated endocytosis in endothelial cells. J Biol Chem (2004) 1.31
Kruppel-like factor-4 transcriptionally regulates VE-cadherin expression and endothelial barrier function. Circ Res (2010) 1.29
Vesicle formation and trafficking in endothelial cells and regulation of endothelial barrier function. Histochem Cell Biol (2002) 1.28
Role of neutrophil NADPH oxidase in the mechanism of tumor necrosis factor-alpha -induced NF-kappa B activation and intercellular adhesion molecule-1 expression in endothelial cells. J Biol Chem (2001) 1.27
Protease-activated receptor-1 activation of endothelial cells induces protein kinase Calpha-dependent phosphorylation of syntaxin 4 and Munc18c: role in signaling p-selectin expression. J Biol Chem (2004) 1.25
Role of NF-kappaB-dependent caveolin-1 expression in the mechanism of increased endothelial permeability induced by lipopolysaccharide. J Biol Chem (2007) 1.25
Activation of NLRP3 inflammasome in alveolar macrophages contributes to mechanical stretch-induced lung inflammation and injury. J Immunol (2013) 1.24
TLR4 activation of TRPC6-dependent calcium signaling mediates endotoxin-induced lung vascular permeability and inflammation. J Exp Med (2012) 1.24
Filamin A regulates caveolae internalization and trafficking in endothelial cells. Mol Biol Cell (2009) 1.24
E3 ubiquitin ligase Cblb regulates the acute inflammatory response underlying lung injury. Nat Med (2007) 1.22
Requisite role of the cholinergic alpha7 nicotinic acetylcholine receptor pathway in suppressing Gram-negative sepsis-induced acute lung inflammatory injury. J Immunol (2009) 1.21
Regulation of endothelial permeability by Src kinase signaling: vascular leakage versus transcellular transport of drugs and macromolecules. Chem Biol Interact (2007) 1.20