PubRank

Lars Kjer-Nielsen

Author PubWeight™ 76.49‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 CD1d-lipid-antigen recognition by the semi-invariant NKT T-cell receptor. Nature 2007 5.31
2 Differential recognition of CD1d-alpha-galactosyl ceramide by the V beta 8.2 and V beta 7 semi-invariant NKT T cell receptors. Immunity 2009 2.61
3 A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule. Nat Immunol 2007 2.55
4 T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide. Nat Immunol 2005 2.52
5 Immune self-reactivity triggered by drug-modified HLA-peptide repertoire. Nature 2012 2.46
6 The CDR3 regions of an immunodominant T cell receptor dictate the 'energetic landscape' of peptide-MHC recognition. Nat Immunol 2005 2.38
7 T cell allorecognition via molecular mimicry. Immunity 2009 2.25
8 The shaping of T cell receptor recognition by self-tolerance. Immunity 2009 2.06
9 Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells. J Exp Med 2013 2.04
10 Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands. EMBO J 2009 1.88
11 T cell receptor CDR2 beta and CDR3 beta loops collaborate functionally to shape the iNKT cell repertoire. Immunity 2009 1.85
12 Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity. Immunity 2008 1.76
13 A naturally selected dimorphism within the HLA-B44 supertype alters class I structure, peptide repertoire, and T cell recognition. J Exp Med 2003 1.72
14 Structural insight into MR1-mediated recognition of the mucosal associated invariant T cell receptor. J Exp Med 2012 1.71
15 High resolution structures of highly bulged viral epitopes bound to major histocompatibility complex class I. Implications for T-cell receptor engagement and T-cell immunodominance. J Biol Chem 2005 1.63
16 Recognition of vitamin B metabolites by mucosal-associated invariant T cells. Nat Commun 2013 1.61
17 Hard wiring of T cell receptor specificity for the major histocompatibility complex is underpinned by TCR adaptability. Proc Natl Acad Sci U S A 2010 1.60
18 A minimal binding footprint on CD1d-glycolipid is a basis for selection of the unique human NKT TCR. J Exp Med 2008 1.60
19 Antigen recognition by CD1d-restricted NKT T cell receptors. Semin Immunol 2009 1.53
20 GRIP domain-mediated targeting of two new coiled-coil proteins, GCC88 and GCC185, to subcompartments of the trans-Golgi network. J Biol Chem 2002 1.48
21 T-cell receptor bias and immunity. Curr Opin Immunol 2008 1.47
22 A semi-invariant Vα10+ T cell antigen receptor defines a population of natural killer T cells with distinct glycolipid antigen-recognition properties. Nat Immunol 2011 1.47
23 Natural HLA class I polymorphism controls the pathway of antigen presentation and susceptibility to viral evasion. J Exp Med 2004 1.43
24 Antigen ligation triggers a conformational change within the constant domain of the alphabeta T cell receptor. Immunity 2009 1.40
25 The structural basis for autonomous dimerization of the pre-T-cell antigen receptor. Nature 2010 1.35
26 CTL recognition of a bulged viral peptide involves biased TCR selection. J Immunol 2005 1.33
27 The production, purification and crystallization of a soluble heterodimeric form of a highly selected T-cell receptor in its unliganded and liganded state. Acta Crystallogr D Biol Crystallogr 2002 1.31
28 The immunogenicity of a viral cytotoxic T cell epitope is controlled by its MHC-bound conformation. J Exp Med 2005 1.28
29 Structural basis for a major histocompatibility complex class Ib-restricted T cell response. Nat Immunol 2006 1.23
30 Crystal structure of HLA-G: a nonclassical MHC class I molecule expressed at the fetal-maternal interface. Proc Natl Acad Sci U S A 2005 1.20
31 Allelic polymorphism in the T cell receptor and its impact on immune responses. J Exp Med 2010 1.18
32 TCR alpha genes direct MHC restriction in the potent human T cell response to a class I-bound viral epitope. J Immunol 2006 1.18
33 Mucosal-associated invariant T cell alterations in obese and type 2 diabetic patients. J Clin Invest 2015 1.15
34 Disparate thermodynamics governing T cell receptor-MHC-I interactions implicate extrinsic factors in guiding MHC restriction. Proc Natl Acad Sci U S A 2006 1.12
35 Functional and structural characteristics of NY-ESO-1-related HLA A2-restricted epitopes and the design of a novel immunogenic analogue. J Biol Chem 2004 1.10
36 Identification of a dominant self-ligand bound to three HLA B44 alleles and the preliminary crystallographic analysis of recombinant forms of each complex. FEBS Lett 2002 1.02
37 Alloreactivity between disparate cognate and allogeneic pMHC-I complexes is the result of highly focused, peptide-dependent structural mimicry. J Biol Chem 2006 1.01
38 Vβ2 natural killer T cell antigen receptor-mediated recognition of CD1d-glycolipid antigen. Proc Natl Acad Sci U S A 2011 0.98
39 T cell allorecognition and MHC restriction--A case of Jekyll and Hyde? Mol Immunol 2007 0.97
40 Structural studies on HLA-G: implications for ligand and receptor binding. Hum Immunol 2006 0.95
41 A structural basis for varied αβ TCR usage against an immunodominant EBV antigen restricted to a HLA-B8 molecule. J Immunol 2011 0.94
42 The impact of human leukocyte antigen (HLA) micropolymorphism on ligand specificity within the HLA-B*41 allotypic family. Haematologica 2010 0.93
43 Structural insight into natural killer T cell receptor recognition of CD1d. Adv Exp Med Biol 2007 0.93
44 The structure of H-2K(b) and K(bm8) complexed to a herpes simplex virus determinant: evidence for a conformational switch that governs T cell repertoire selection and viral resistance. J Immunol 2004 0.90
45 Antigen-driven patterns of TCR bias are shared across diverse outcomes of human hepatitis C virus infection. J Immunol 2010 0.88
46 The structural bases of direct T-cell allorecognition: implications for T-cell-mediated transplant rejection. Immunol Cell Biol 2011 0.87
47 Antagonism of antiviral and allogeneic activity of a human public CTL clonotype by a single altered peptide ligand: implications for allograft rejection. J Immunol 2005 0.86
48 Identification of a Golgi-localised GRIP domain protein from Arabidopsis thaliana. Planta 2004 0.85
49 Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands. EMBO J 2009 0.82
50 The structure and stability of the monomorphic HLA-G are influenced by the nature of the bound peptide. J Mol Biol 2010 0.81
51 The production, purification and crystallization of a soluble form of the nonclassical MHC HLA-G: the essential role of cobalt. Acta Crystallogr Sect F Struct Biol Cryst Commun 2005 0.80
52 Structural studies on the alphabeta T-cell receptor. IUBMB Life 2005 0.80
53 The production and purification of the human T-cell receptors, the CD3epsilongamma and CD3epsilondelta heterodimers: complex formation and crystallization with OKT3, a therapeutic monoclonal antibody. Acta Crystallogr D Biol Crystallogr 2004 0.76