Published in Immunity on May 21, 2009
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The structural basis for autonomous dimerization of the pre-T-cell antigen receptor. Nature (2010) 1.35
Organization of proximal signal initiation at the TCR:CD3 complex. Immunol Rev (2009) 1.25
Evidence for a functional sidedness to the alphabetaTCR. Proc Natl Acad Sci U S A (2010) 1.24
Allelic polymorphism in the T cell receptor and its impact on immune responses. J Exp Med (2010) 1.18
Interplay between T cell receptor binding kinetics and the level of cognate peptide presented by major histocompatibility complexes governs CD8+ T cell responsiveness. J Biol Chem (2012) 1.16
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Overcoming the memory barrier in tolerance induction: molecular mimicry and functional heterogeneity among pathogen-specific T-cell populations. Curr Opin Organ Transplant (2010) 1.07
T cell receptor triggering by force. Trends Immunol (2010) 1.04
Distinctive CD3 heterodimeric ectodomain topologies maximize antigen-triggered activation of alpha beta T cell receptors. J Immunol (2010) 1.03
Cutting edge: Evidence for a dynamically driven T cell signaling mechanism. J Immunol (2012) 1.03
A conserved CXXC motif in CD3epsilon is critical for T cell development and TCR signaling. PLoS Biol (2009) 0.94
Peptide-major histocompatibility complex dimensions control proximal kinase-phosphatase balance during T cell activation. J Biol Chem (2009) 0.93
Molecular architecture of the αβ T cell receptor-CD3 complex. Proc Natl Acad Sci U S A (2014) 0.93
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Rigid-body ligand recognition drives cytotoxic T-lymphocyte antigen 4 (CTLA-4) receptor triggering. J Biol Chem (2010) 0.86
Structure of Staphylococcal Enterotoxin E in Complex with TCR Defines the Role of TCR Loop Positioning in Superantigen Recognition. PLoS One (2015) 0.82
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Sulfamethoxazole induces a switch mechanism in T cell receptors containing TCRVβ20-1, altering pHLA recognition. PLoS One (2013) 0.77
Indoctrinating T cells to attack pathogens through homeschooling. Trends Immunol (2015) 0.77
Inside the microcluster: antigen receptor signalling viewed with molecular imaging tools. Immunology (2011) 0.77
Quantitative Analysis of the Association Angle between T-cell Receptor Vα/Vβ Domains Reveals Important Features for Epitope Recognition. PLoS Comput Biol (2015) 0.76
Early T-cell activation biophysics. HFSP J (2009) 0.75
A conserved αβ transmembrane interface forms the core of a compact T-cell receptor-CD3 structure within the membrane. Proc Natl Acad Sci U S A (2016) 0.75
Lipid-dependent conformational dynamics underlie the functional versatility of T-cell receptor. Cell Res (2017) 0.75
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CD1d-lipid-antigen recognition by the semi-invariant NKT T-cell receptor. Nature (2007) 5.31
Size-distribution analysis of proteins by analytical ultracentrifugation: strategies and application to model systems. Biophys J (2002) 5.20
Linear ubiquitination prevents inflammation and regulates immune signalling. Nature (2011) 4.85
Identification of a nitroimidazo-oxazine-specific protein involved in PA-824 resistance in Mycobacterium tuberculosis. Proc Natl Acad Sci U S A (2005) 3.97
MR1 presents microbial vitamin B metabolites to MAIT cells. Nature (2012) 3.71
AB5 subtilase cytotoxin inactivates the endoplasmic reticulum chaperone BiP. Nature (2006) 3.65
A common fold mediates vertebrate defense and bacterial attack. Science (2007) 3.43
A structural basis for the selection of dominant alphabeta T cell receptors in antiviral immunity. Immunity (2003) 3.41
Germline-encoded recognition of diverse glycolipids by natural killer T cells. Nat Immunol (2007) 3.19
Structural determinants of T-cell receptor bias in immunity. Nat Rev Immunol (2006) 3.01
Structural evidence for a germline-encoded T cell receptor-major histocompatibility complex interaction 'codon'. Nat Immunol (2007) 2.78
Reactive oxygen species enhance insulin sensitivity. Cell Metab (2009) 2.77
More than one reason to rethink the use of peptides in vaccine design. Nat Rev Drug Discov (2007) 2.68
Inositol polyphosphate 4-phosphatase II regulates PI3K/Akt signaling and is lost in human basal-like breast cancers. Proc Natl Acad Sci U S A (2010) 2.67
Differential recognition of CD1d-alpha-galactosyl ceramide by the V beta 8.2 and V beta 7 semi-invariant NKT T cell receptors. Immunity (2009) 2.61
A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule. Nat Immunol (2007) 2.55
T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide. Nat Immunol (2005) 2.52
Immune self-reactivity triggered by drug-modified HLA-peptide repertoire. Nature (2012) 2.46
Lack of prominent peptide-major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations. Nat Immunol (2005) 2.44
Recognition of β-linked self glycolipids mediated by natural killer T cell antigen receptors. Nat Immunol (2011) 2.42
The structural basis of Janus kinase 2 inhibition by a potent and specific pan-Janus kinase inhibitor. Blood (2005) 2.41
The CDR3 regions of an immunodominant T cell receptor dictate the 'energetic landscape' of peptide-MHC recognition. Nat Immunol (2005) 2.38
The molecular basis of TCR germline bias for MHC is surprisingly simple. Nat Immunol (2009) 2.34
Crossreactive T Cells spotlight the germline rules for alphabeta T cell-receptor interactions with MHC molecules. Immunity (2008) 2.31
T cell allorecognition via molecular mimicry. Immunity (2009) 2.25
The 2.0-A crystal structure of eqFP611, a far red fluorescent protein from the sea anemone Entacmaea quadricolor. J Biol Chem (2003) 2.23
The structural basis for membrane binding and pore formation by lymphocyte perforin. Nature (2010) 2.23
Predisposition to abacavir hypersensitivity conferred by HLA-B*5701 and a haplotypic Hsp70-Hom variant. Proc Natl Acad Sci U S A (2004) 2.15
The MACPF/CDC family of pore-forming toxins. Cell Microbiol (2008) 2.15
Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin. Nature (2008) 2.11
A molecular basis for the exquisite CD1d-restricted antigen specificity and functional responses of natural killer T cells. Immunity (2011) 2.11
The shaping of T cell receptor recognition by self-tolerance. Immunity (2009) 2.06
Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells. J Exp Med (2013) 2.04
The type III effectors NleE and NleB from enteropathogenic E. coli and OspZ from Shigella block nuclear translocation of NF-kappaB p65. PLoS Pathog (2010) 2.03