Published in Neuron on April 20, 2006
Calmodulin-kinases: modulators of neuronal development and plasticity. Neuron (2008) 3.14
Genome-wide association studies identify loci associated with age at menarche and age at natural menopause. Nat Genet (2009) 3.06
Terminal axon branching is regulated by the LKB1-NUAK1 kinase pathway via presynaptic mitochondrial capture. Cell (2013) 2.92
Loss of alpha-tubulin polyglutamylation in ROSA22 mice is associated with abnormal targeting of KIF1A and modulated synaptic function. Proc Natl Acad Sci U S A (2007) 2.04
Hierarchical assembly of presynaptic components in defined C. elegans synapses. Nat Neurosci (2006) 1.66
SCRAPPER-dependent ubiquitination of active zone protein RIM1 regulates synaptic vesicle release. Cell (2007) 1.60
RIM1alpha and RIM1beta are synthesized from distinct promoters of the RIM1 gene to mediate differential but overlapping synaptic functions. J Neurosci (2008) 1.21
Synaptic activity prompts gamma-secretase-mediated cleavage of EphA4 and dendritic spine formation. J Cell Biol (2009) 1.19
Analysis of Alzheimer's disease severity across brain regions by topological analysis of gene co-expression networks. BMC Syst Biol (2010) 1.11
Cellular and molecular determinants targeting the Caenorhabditis elegans PHR protein RPM-1 to perisynaptic regions. Dev Dyn (2008) 1.08
Fbxo45, a novel ubiquitin ligase, regulates synaptic activity. J Biol Chem (2009) 1.08
A chemical-genetic strategy reveals distinct temporal requirements for SAD-1 kinase in neuronal polarization and synapse formation. Neural Dev (2008) 0.96
Investigating the regulation of brain-specific kinases 1 and 2 by phosphorylation. J Biol Chem (2008) 0.95
Polarized activities of AMPK and BRSK in primary hippocampal neurons. Mol Biol Cell (2015) 0.95
SAD kinases sculpt axonal arbors of sensory neurons through long- and short-term responses to neurotrophin signals. Neuron (2013) 0.95
Bruchpilot in ribbon-like axonal agglomerates, behavioral defects, and early death in SRPK79D kinase mutants of Drosophila. PLoS Genet (2009) 0.91
Synapses of amphids defective (SAD-A) kinase promotes glucose-stimulated insulin secretion through activation of p21-activated kinase (PAK1) in pancreatic β-Cells. J Biol Chem (2012) 0.89
Sugar-free frosting, a homolog of SAD kinase, drives neural-specific glycan expression in the Drosophila embryo. Development (2011) 0.88
Integrated Transcriptome and Proteome Analyses Reveal Organ-Specific Proteome Deterioration in Old Rats. Cell Syst (2015) 0.88
Brain-selective kinase 2 (BRSK2) phosphorylation on PCTAIRE1 negatively regulates glucose-stimulated insulin secretion in pancreatic β-cells. J Biol Chem (2012) 0.86
SAD-A kinase controls islet β-cell size and function as a mediator of mTORC1 signaling. Proc Natl Acad Sci U S A (2013) 0.85
Transmembrane and ubiquitin-like domain-containing protein 1 (Tmub1/HOPS) facilitates surface expression of GluR2-containing AMPA receptors. PLoS One (2008) 0.85
SAD-A potentiates glucose-stimulated insulin secretion as a mediator of glucagon-like peptide 1 response in pancreatic β cells. Mol Cell Biol (2013) 0.84
SCRAPPER regulates the thresholds of long-term potentiation/depression, the bidirectional synaptic plasticity in hippocampal CA3-CA1 synapses. Neural Plast (2012) 0.81
APC/C(Cdh1) targets brain-specific kinase 2 (BRSK2) for degradation via the ubiquitin-proteasome pathway. PLoS One (2012) 0.79
SAD kinases control the maturation of nerve terminals in the mammalian peripheral and central nervous systems. Proc Natl Acad Sci U S A (2014) 0.79
The long and the short of SAD-1 kinase. Commun Integr Biol (2010) 0.78
Neuronal development: SAD kinases make happy axons. Curr Biol (2013) 0.77
Structural insight into the mechanism of synergistic autoinhibition of SAD kinases. Nat Commun (2015) 0.76
Genome-Wide Association of Heroin Dependence in Han Chinese. PLoS One (2016) 0.75
Genetic variants of age at menopause are not related to timing of ovarian failure in breast cancer survivors. Menopause (2017) 0.75
Age at menarche and age at natural menopause in East Asian women: a genome-wide association study. Age (Dordr) (2016) 0.75
HIV and Cocaine Impact Glial Metabolism: Energy Sensor AMP-activated protein kinase Role in Mitochondrial Biogenesis and Epigenetic Remodeling. Sci Rep (2016) 0.75
Transcriptomic Analysis of Ribosome-Bound mRNA in Cortical Neurites In Vivo. J Neurosci (2017) 0.75
CLASPs attach microtubule plus ends to the cell cortex through a complex with LL5beta. Dev Cell (2006) 2.99
Tubulin tyrosination navigates the kinesin-1 motor domain to axons. Nat Neurosci (2009) 2.55
The TRPM7 ion channel functions in cholinergic synaptic vesicles and affects transmitter release. Neuron (2006) 2.50
CD38 is critical for social behaviour by regulating oxytocin secretion. Nature (2007) 2.44
Rab6 regulates transport and targeting of exocytotic carriers. Dev Cell (2007) 2.32
Biochemical and structural definition of the l-afadin- and actin-binding sites of alpha-catenin. J Biol Chem (2002) 2.31
Modification of mineralocorticoid receptor function by Rac1 GTPase: implication in proteinuric kidney disease. Nat Med (2008) 2.25
Doc2b is a high-affinity Ca2+ sensor for spontaneous neurotransmitter release. Science (2010) 2.12
Loss of alpha-tubulin polyglutamylation in ROSA22 mice is associated with abnormal targeting of KIF1A and modulated synaptic function. Proc Natl Acad Sci U S A (2007) 2.04
RhoGDI-1 modulation of the activity of monomeric RhoGTPase RhoA regulates endothelial barrier function in mouse lungs. Circ Res (2007) 1.99
Mutations of the catalytic subunit of RAB3GAP cause Warburg Micro syndrome. Nat Genet (2005) 1.98
Predicted expansion of the claudin multigene family. FEBS Lett (2011) 1.91
Molecular perspective on tight-junction assembly and epithelial polarity. Adv Drug Deliv Rev (2005) 1.88
Implications of nectin-like molecule-2/IGSF4/RA175/SgIGSF/TSLC1/SynCAM1 in cell-cell adhesion and transmembrane protein localization in epithelial cells. J Biol Chem (2003) 1.86
Three-dimensional architecture of presynaptic terminal cytomatrix. J Neurosci (2007) 1.82
Alternative entry receptors for herpes simplex virus and their roles in disease. Cell Host Microbe (2007) 1.78
Nectins establish a checkerboard-like cellular pattern in the auditory epithelium. Science (2011) 1.76
LIS1 and NDEL1 coordinate the plus-end-directed transport of cytoplasmic dynein. EMBO J (2008) 1.72
Tight junctions in Schwann cells of peripheral myelinated axons: a lesson from claudin-19-deficient mice. J Cell Biol (2005) 1.69
Cast: a novel protein of the cytomatrix at the active zone of synapses that forms a ternary complex with RIM1 and munc13-1. J Cell Biol (2002) 1.65
KIF17 dynamics and regulation of NR2B trafficking in hippocampal neurons. J Neurosci (2003) 1.64
Deficiency of zonula occludens-1 causes embryonic lethal phenotype associated with defected yolk sac angiogenesis and apoptosis of embryonic cells. Mol Biol Cell (2008) 1.63
Reveromycin A biosynthesis uses RevG and RevJ for stereospecific spiroacetal formation. Nat Chem Biol (2011) 1.62
Direct binding of cell polarity protein PAR-3 to cell-cell adhesion molecule nectin at neuroepithelial cells of developing mouse. J Biol Chem (2003) 1.60
SCRAPPER-dependent ubiquitination of active zone protein RIM1 regulates synaptic vesicle release. Cell (2007) 1.60
Nectin: an adhesion molecule involved in formation of synapses. J Cell Biol (2002) 1.57
CRTAM confers late-stage activation of CD8+ T cells to regulate retention within lymph node. J Immunol (2009) 1.57
Nectin couples cell-cell adhesion and the actin scaffold at heterotypic testicular junctions. Curr Biol (2002) 1.55
CEP41 is mutated in Joubert syndrome and is required for tubulin glutamylation at the cilium. Nat Genet (2012) 1.54
TTLL7 is a mammalian beta-tubulin polyglutamylase required for growth of MAP2-positive neurites. J Biol Chem (2006) 1.53
Regulation of E-cadherin endocytosis by nectin through afadin, Rap1, and p120ctn. J Biol Chem (2005) 1.52
Visualization of the cell-selective distribution of PUFA-containing phosphatidylcholines in mouse brain by imaging mass spectrometry. J Lipid Res (2009) 1.52
Endocytosis of E-cadherin regulated by Rac and Cdc42 small G proteins through IQGAP1 and actin filaments. J Cell Biol (2004) 1.52
Deficiency of nectin-2 leads to cardiac fibrosis and dysfunction under chronic pressure overload. Hypertension (2009) 1.50
Imaging mass spectrometry evaluation of the effects of various irrigation fluids in a rat model of postoperative cerebral edema. World Neurosurg (2011) 1.50
Physical and functional interaction of the active zone proteins, CAST, RIM1, and Bassoon, in neurotransmitter release. J Cell Biol (2004) 1.48
GPHR-dependent functions of the Golgi apparatus are essential for the formation of lamellar granules and the skin barrier. J Invest Dermatol (2012) 1.48
Regulation of the assembly and adhesion activity of E-cadherin by nectin and afadin for the formation of adherens junctions in Madin-Darby canine kidney cells. J Biol Chem (2005) 1.46
Expression of human Gaucher disease gene GBA generates neurodevelopmental defects and ER stress in Drosophila eye. PLoS One (2013) 1.45
Structural and functional associations of apical junctions with cytoskeleton. Biochim Biophys Acta (2007) 1.45
Involvement of Cdc42 and Rac small G proteins in invadopodia formation of RPMI7951 cells. Genes Cells (2003) 1.43
Association of ASIP/mPAR-3 with adherens junctions of mouse neuroepithelial cells. Dev Dyn (2002) 1.39
MALDI-based imaging mass spectrometry revealed abnormal distribution of phospholipids in colon cancer liver metastasis. J Chromatogr B Analyt Technol Biomed Life Sci (2007) 1.36
The roles of nectins in cell adhesions: cooperation with other cell adhesion molecules and growth factor receptors. Curr Opin Cell Biol (2007) 1.36
Rac1 GTPase in rodent kidneys is essential for salt-sensitive hypertension via a mineralocorticoid receptor-dependent pathway. J Clin Invest (2011) 1.35
Cooperative roles of Par-3 and afadin in the formation of adherens and tight junctions. J Cell Sci (2007) 1.35
Roles of cell-adhesion molecules nectin 1 and nectin 3 in ciliary body development. Development (2005) 1.34
Overexpression of motor protein KIF17 enhances spatial and working memory in transgenic mice. Proc Natl Acad Sci U S A (2002) 1.33
Tubulin polyglutamylation is essential for airway ciliary function through the regulation of beating asymmetry. Proc Natl Acad Sci U S A (2010) 1.33
Role of the yeast acetyltransferase Mpr1 in oxidative stress: regulation of oxygen reactive species caused by a toxic proline catabolism intermediate. Proc Natl Acad Sci U S A (2004) 1.33
Nectins and nectin-like molecules: roles in cell adhesion, polarization, movement, and proliferation. IUBMB Life (2006) 1.32
Interneurite affinity is regulated by heterophilic nectin interactions in concert with the cadherin machinery. J Cell Biol (2006) 1.31
Biology and pathology of nectins and nectin-like molecules. Curr Opin Cell Biol (2004) 1.31
Imaging mass spectrometry technology and application on ganglioside study; visualization of age-dependent accumulation of C20-ganglioside molecular species in the mouse hippocampus. PLoS One (2008) 1.31
She4p/Dim1p interacts with the motor domain of unconventional myosins in the budding yeast, Saccharomyces cerevisiae. Mol Biol Cell (2003) 1.29
PKA-catalyzed phosphorylation of tomosyn and its implication in Ca2+-dependent exocytosis of neurotransmitter. J Cell Biol (2005) 1.29
JAM4, a junctional cell adhesion molecule interacting with a tight junction protein, MAGI-1. Mol Cell Biol (2003) 1.28
Identification of tubulin deglutamylase among Caenorhabditis elegans and mammalian cytosolic carboxypeptidases (CCPs). J Biol Chem (2010) 1.27
Interaction of synaptic scaffolding molecule and Beta -catenin. J Neurosci (2002) 1.26
Involvement of the c-Src-Crk-C3G-Rap1 signaling in the nectin-induced activation of Cdc42 and formation of adherens junctions. J Biol Chem (2004) 1.26
Mass imaging and identification of biomolecules with MALDI-QIT-TOF-based system. Anal Chem (2008) 1.25
Loss of nectin-2 at Sertoli-spermatid junctions leads to male infertility and correlates with severe spermatozoan head and midpiece malformation, impaired binding to the zona pellucida, and oocyte penetration. Biol Reprod (2003) 1.24
Rap1-PDZ-GEF1 interacts with a neurotrophin receptor at late endosomes, leading to sustained activation of Rap1 and ERK and neurite outgrowth. J Cell Biol (2007) 1.23
Maintenance of neuronal positions in organized ganglia by SAX-7, a Caenorhabditis elegans homologue of L1. EMBO J (2005) 1.21
CREM-dependent transcription in male germ cells controlled by a kinesin. Science (2002) 1.20
Antagonistic and agonistic effects of an extracellular fragment of nectin on formation of E-cadherin-based cell-cell adhesion. Genes Cells (2003) 1.20
Activation of Cdc42 by trans interactions of the cell adhesion molecules nectins through c-Src and Cdc42-GEF FRG. J Cell Biol (2004) 1.20
Involvement of LMO7 in the association of two cell-cell adhesion molecules, nectin and E-cadherin, through afadin and alpha-actinin in epithelial cells. J Biol Chem (2004) 1.19
Direct binding of Lgl2 to LGN during mitosis and its requirement for normal cell division. J Biol Chem (2005) 1.19
Synaptic activity prompts gamma-secretase-mediated cleavage of EphA4 and dendritic spine formation. J Cell Biol (2009) 1.19
N-acetyltransferase ARD1-NAT1 regulates neuronal dendritic development. Genes Cells (2008) 1.19
V-ATPase membrane sector associates with synaptobrevin to modulate neurotransmitter release. Neuron (2010) 1.19
Epsilon-poly-L-lysine dispersity is controlled by a highly unusual nonribosomal peptide synthetase. Nat Chem Biol (2008) 1.19
Rab3 GTPase-activating protein regulates synaptic transmission and plasticity through the inactivation of Rab3. Proc Natl Acad Sci U S A (2006) 1.18
Role of nectin in organization of tight junctions in epithelial cells. Genes Cells (2002) 1.18
Involvement of nectins in the formation of puncta adherentia junctions and the mossy fiber trajectory in the mouse hippocampus. Mol Cell Neurosci (2005) 1.18
Paradoxical ATP elevation in ischemic penumbra revealed by quantitative imaging mass spectrometry. Antioxid Redox Signal (2010) 1.18
Differential distribution of release-related proteins in the hippocampal CA3 area as revealed by freeze-fracture replica labeling. J Comp Neurol (2005) 1.18
Role of each immunoglobulin-like loop of nectin for its cell-cell adhesion activity. Biochem Biophys Res Commun (2003) 1.17
Roles and modes of action of nectins in cell-cell adhesion. Semin Cell Dev Biol (2004) 1.17