Published in FEBS Lett on January 26, 2011
Claudins and the modulation of tight junction permeability. Physiol Rev (2013) 2.05
Tight junctions at the blood brain barrier: physiological architecture and disease-associated dysregulation. Fluids Barriers CNS (2012) 1.44
Claudin-14 regulates renal Ca⁺⁺ transport in response to CaSR signalling via a novel microRNA pathway. EMBO J (2012) 1.40
Architecture of tight junctions and principles of molecular composition. Semin Cell Dev Biol (2014) 1.21
Tight junction proteins: from barrier to tumorigenesis. Cancer Lett (2013) 1.14
Claudins and the kidney. Annu Rev Physiol (2012) 1.11
Claudin interactions in and out of the tight junction. Tissue Barriers (2013) 1.08
European sea bass genome and its variation provide insights into adaptation to euryhalinity and speciation. Nat Commun (2014) 1.07
Tight junctions in lung cancer and lung metastasis: a review. Int J Clin Exp Pathol (2012) 1.05
Coordinating the impact of structural genomics on the human α-helical transmembrane proteome. Nat Struct Mol Biol (2013) 1.05
Claudins in lung diseases. Respir Res (2011) 1.05
Deletion of claudin-10 (Cldn10) in the thick ascending limb impairs paracellular sodium permeability and leads to hypermagnesemia and nephrocalcinosis. Proc Natl Acad Sci U S A (2012) 1.02
Laser-capture microdissection and transcriptional profiling of the dorsomedial nucleus of the hypothalamus. J Comp Neurol (2012) 0.95
The blood-epididymis barrier and inflammation. Spermatogenesis (2014) 0.94
Regulation of the Epithelial-Mesenchymal Transition by Claudin-3 and Claudin-4. PLoS One (2013) 0.94
Claudins play a role in normal and tumor cell motility. BMC Cell Biol (2013) 0.93
The kidney tight junction (Review). Int J Mol Med (2014) 0.92
"You Shall Not Pass"-tight junctions of the blood brain barrier. Front Neurosci (2014) 0.92
Methylation of the claudin 1 promoter is associated with loss of expression in estrogen receptor positive breast cancer. PLoS One (2013) 0.91
Distinct claudin expression profiles of hepatocellular carcinoma and metastatic colorectal and pancreatic carcinomas. J Histochem Cytochem (2013) 0.88
Tight junctions in human pancreatic duct epithelial cells. Tissue Barriers (2013) 0.87
Proteomic analysis of proteins surrounding occludin and claudin-4 reveals their proximity to signaling and trafficking networks. PLoS One (2015) 0.87
Paracellular epithelial sodium transport maximizes energy efficiency in the kidney. J Clin Invest (2016) 0.87
Barriers of the peripheral nerve. Tissue Barriers (2013) 0.87
Possible involvement of tight junctions, extracellular matrix and nuclear receptors in epithelial differentiation. J Biomed Biotechnol (2011) 0.87
A CLDN1-negative phenotype predicts poor prognosis in triple-negative breast cancer. PLoS One (2014) 0.86
Claudin 4 knockout mice: normal physiological phenotype with increased susceptibility to lung injury. Am J Physiol Lung Cell Mol Physiol (2014) 0.86
Apoptosis signal-regulating kinase 1 is associated with the effect of claudin-6 in breast cancer. Diagn Pathol (2012) 0.86
Regulation of tight junctions in upper airway epithelium. Biomed Res Int (2012) 0.86
Gastrointestinal mucosal barrier function and diseases. J Gastroenterol (2016) 0.85
Redox-sensitive structure and function of the first extracellular loop of the cell-cell contact protein claudin-1: lessons from molecular structure to animals. Antioxid Redox Signal (2015) 0.85
Claudin-2 knockout by TALEN-mediated gene targeting in MDCK cells: claudin-2 independently determines the leaky property of tight junctions in MDCK cells. PLoS One (2015) 0.84
Lecture: New light on the role of claudins in the kidney. Organogenesis (2012) 0.84
Regulation of claudins in blood-tissue barriers under physiological and pathological states. Tissue Barriers (2013) 0.84
Myofibroblast keratinocyte growth factor reduces tight junctional integrity and increases claudin-2 levels in polarized Caco-2 cells. Growth Factors (2012) 0.83
Targeting tight junctions during epithelial to mesenchymal transition in human pancreatic cancer. World J Gastroenterol (2014) 0.82
Tumor necrosis factor-α induces a biphasic change in claudin-2 expression in tubular epithelial cells: role in barrier functions. Am J Physiol Cell Physiol (2015) 0.82
Claudin-3 overexpression increases the malignant potential of colorectal cancer cells: roles of ERK1/2 and PI3K-Akt as modulators of EGFR signaling. PLoS One (2013) 0.82
The four-transmembrane protein IP39 of Euglena forms strands by a trimeric unit repeat. Nat Commun (2013) 0.81
Epidermal growth factor modulates claudins and tight junctional functions in ovarian cancer cell lines. Histochem Cell Biol (2012) 0.81
Quercetin Decreases Claudin-2 Expression Mediated by Up-Regulation of microRNA miR-16 in Lung Adenocarcinoma A549 Cells. Nutrients (2015) 0.80
Role of grainyhead-like 2 in the formation of functional tight junctions. Tissue Barriers (2013) 0.80
The claudin Megatrachea protein complex. J Biol Chem (2012) 0.80
Slug is associated with poor survival in squamous cell carcinoma of the lung. Int J Clin Exp Pathol (2014) 0.80
Claudins 10 and 18 are predominantly expressed in lung adenocarcinomas and in tumors of nonsmokers. Int J Clin Exp Pathol (2011) 0.79
High Expression of the Newly Found Long Noncoding RNA Z38 Promotes Cell Proliferation and Oncogenic Activity in Breast Cancer. J Cancer (2016) 0.79
Tight junction disruption: Helicobacter pylori and dysregulation of the gastric mucosal barrier. World J Gastroenterol (2015) 0.79
Systems Proteomics View of the Endogenous Human Claudin Protein Family. J Proteome Res (2016) 0.79
Interferon-gamma increased epithelial barrier function via upregulating claudin-7 expression in human submandibular gland duct epithelium. J Mol Histol (2016) 0.78
Trends in drug delivery through tissue barriers containing tight junctions. Tissue Barriers (2013) 0.78
Claudin-18 in biliary neoplasms. Its significance in the classification of intrahepatic cholangiocarcinoma. Virchows Arch (2011) 0.78
Claudin-4 forms a paracellular barrier, revealing the interdependence of claudin expression in the loose epithelial cell culture model opossum kidney cells. Am J Physiol Cell Physiol (2012) 0.78
HNF4α regulates claudin-7 protein expression during intestinal epithelial differentiation. Am J Pathol (2015) 0.78
The interaction of Clostridium perfringens enterotoxin with receptor claudins. Anaerobe (2016) 0.78
Familial hypomagnesaemia with hypercalciuria and nephrocalcinosis: clinical and molecular characteristics. Clin Kidney J (2015) 0.78
Brain Invasion by Mouse Hepatitis Virus Depends on Impairment of Tight Junctions and Beta Interferon Production in Brain Microvascular Endothelial Cells. J Virol (2015) 0.77
The role of claudin in hypercalciuric nephrolithiasis. Curr Urol Rep (2013) 0.77
Hepatocyte growth factor stimulates the migration of gastric epithelial cells by altering the subcellular localization of the tight junction protein ZO-1. J Gastroenterol (2012) 0.77
Down Regulation of CLDND1 Induces Apoptosis in Breast Cancer Cells. PLoS One (2015) 0.77
Emerging multifunctional roles of Claudin tight junction proteins in bone. Endocrinology (2014) 0.77
A high-calcium diet failed to rescue an osteopenia phenotype in claudin-18 knockout mice. Physiol Rep (2014) 0.77
Dose-dependent role of claudin-1 in vivo in orchestrating features of atopic dermatitis. Proc Natl Acad Sci U S A (2016) 0.77
Diadenosine tetraphosphate induces tight junction disassembly thus increasing corneal epithelial permeability. Br J Pharmacol (2014) 0.76
Efficacy and safety evaluation of claudin-4-targeted antitumor therapy using a human and mouse cross-reactive monoclonal antibody. Pharmacol Res Perspect (2016) 0.76
Viral interactions with the blood-brain barrier: old dog, new tricks. Tissue Barriers (2016) 0.76
Claudins 1, 2, 3, 4, 5 and 7 in solar keratosis and squamocellular carcinoma of the skin. Int J Clin Exp Pathol (2013) 0.76
Mend Your Fences: The Epithelial Barrier and its Relationship With Mucosal Immunity in Inflammatory Bowel Disease. Cell Mol Gastroenterol Hepatol (2017) 0.76
Claudin-3 expression increases the malignant potential of lung adenocarcinoma cells: role of epidermal growth factor receptor activation. Oncotarget (2017) 0.75
Claudin-1, -2 and -3 Are Selectively Expressed in the Epithelia of the Choroid Plexus of the Mouse from Early Development and into Adulthood While Claudin-5 is Restricted to Endothelial Cells. Front Neuroanat (2016) 0.75
Claudin11 Promoter Hypermethylation Is Frequent in Malignant Melanoma of the Skin, but Uncommon in Nevus Cell Nevi. Cancers (Basel) (2015) 0.75
Differential expression of claudin family members during osteoblast and osteoclast differentiation: Cldn-1 is a novel positive regulator of osteoblastogenesis. PLoS One (2014) 0.75
Longitudinal Claudin Gene Expression Analyses in Canine Mammary Tissues and Thereof Derived Primary Cultures and Cell Lines. Int J Mol Sci (2016) 0.75
Expression of claudin-11, -23 in different gastric tissues and its relationship with the risk and prognosis of gastric cancer. PLoS One (2017) 0.75
Role of tight junctions in signal transduction: an update. EXCLI J (2014) 0.75
Tight junction modulation of the blood brain barrier: CNS delivery of small molecules. Tissue Barriers (2016) 0.75
Identity crisis in the PMP-22/EMP/MP20/Claudin superfamily (Pfam00822). Tissue Barriers (2015) 0.75
Increased urothelial paracellular transport promotes cystitis. Am J Physiol Renal Physiol (2015) 0.75
Topology based identification and comprehensive classification of four-transmembrane helix containing proteins (4TMs) in the human genome. BMC Genomics (2016) 0.75
Claudin 1 expression characterizes human uterine cervical reserve cells. J Histochem Cytochem (2013) 0.75
Endothelial Cell Signaling and Ventilator-Induced Lung Injury (VILI): Molecular Mechanisms, Genomic Analyses & Therapeutic Targets. Am J Physiol Lung Cell Mol Physiol (2016) 0.75
Cardiac functions assessment in children with celiac disease and its correlation with the degree of mucosal injury: Doppler tissue imaging study. Saudi J Gastroenterol (2016) 0.75
Claudin-21 Has a Paracellular Channel Role at Tight Junctions. Mol Cell Biol (2016) 0.75
Claudin-2 expression is upregulated in the ileum of diarrhea predominant irritable bowel syndrome patients. J Clin Biochem Nutr (2017) 0.75
A common variant in CLDN14 causes precipitous, prelingual sensorineural hearing loss in multiple families due to founder effect. Hum Genet (2016) 0.75
Effects of Osmolality on Paracellular Transport in MDCK II Cells. PLoS One (2016) 0.75
Down-Regulation of Claudin-2 Expression and Proliferation by Epigenetic Inhibitors in Human Lung Adenocarcinoma A549 Cells. J Biol Chem (2017) 0.75
Up-regulation of claudin-2 expression by aldosterone in colonic epithelial cells of mice fed with NaCl-depleted diets. Sci Rep (2017) 0.75
SMAD2 Inactivation Inhibits CLDN6 Methylation to Suppress Migration and Invasion of Breast Cancer Cells. Int J Mol Sci (2017) 0.75
Morphological and Functional Analyses of the Tight Junction in the Palatal Epithelium of Mouse. Acta Histochem Cytochem (2017) 0.75
Roles of the first-generation claudin binder, Clostridium perfringens enterotoxin, in the diagnosis and claudin-targeted treatment of epithelium-derived cancers. Pflugers Arch (2016) 0.75
Intestinal epithelial claudins: expression and regulation in homeostasis and inflammation. Ann N Y Acad Sci (2017) 0.75
Non-canonical functions of claudin proteins: Beyond the regulation of cell-cell adhesions. Tissue Barriers (2017) 0.75
An adult multifocal medulloblastoma with diffuse acute postoperative cerebellar swelling: immunohistochemical and molecular genetics analysis. Neurosurg Rev (2014) 0.75
Claudin-4 knockout by TALEN-mediated gene targeting in MDCK cells: Claudin-4 is dispensable for the permeability properties of tight junctions in wild-type MDCK cells. PLoS One (2017) 0.75
A slicer-mediated mechanism for repeat-associated siRNA 5' end formation in Drosophila. Science (2007) 10.73
Klotho converts canonical FGF receptor into a specific receptor for FGF23. Nature (2006) 9.40
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Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism. J Clin Invest (2004) 7.00
FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasis. J Bone Miner Res (2003) 6.81
Drosophila endogenous small RNAs bind to Argonaute 2 in somatic cells. Nature (2008) 5.59
The genome sequence and structure of rice chromosome 1. Nature (2002) 4.99
ZO-1 and ZO-2 independently determine where claudins are polymerized in tight-junction strand formation. Cell (2006) 4.61
Generation of rat pancreas in mouse by interspecific blastocyst injection of pluripotent stem cells. Cell (2010) 4.24
Lack of interleukin-1beta decreases the severity of atherosclerosis in ApoE-deficient mice. Arterioscler Thromb Vasc Biol (2003) 3.18
The molecular basis of vascular lumen formation in the developing mouse aorta. Dev Cell (2009) 3.08
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Vitamin D receptor-independent FGF23 actions in regulating phosphate and vitamin D metabolism. Am J Physiol Renal Physiol (2005) 2.05
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Requirement of ZO-1 for the formation of belt-like adherens junctions during epithelial cell polarization. J Cell Biol (2007) 1.79
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Structural basis of adhesion-molecule recognition by ERM proteins revealed by the crystal structure of the radixin-ICAM-2 complex. EMBO J (2003) 1.70
Tight junctions in Schwann cells of peripheral myelinated axons: a lesson from claudin-19-deficient mice. J Cell Biol (2005) 1.69
Disruption of tumor necrosis factor-alpha gene diminishes the development of atherosclerosis in ApoE-deficient mice. Atherosclerosis (2005) 1.66
Relevant use of Klotho in FGF19 subfamily signaling system in vivo. Proc Natl Acad Sci U S A (2010) 1.66
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Deficiency of zonula occludens-1 causes embryonic lethal phenotype associated with defected yolk sac angiogenesis and apoptosis of embryonic cells. Mol Biol Cell (2008) 1.63
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Recruitment of PCM1 to the centrosome by the cooperative action of DISC1 and BBS4: a candidate for psychiatric illnesses. Arch Gen Psychiatry (2008) 1.51
Melanophilin directly links Rab27a and myosin Va through its distinct coiled-coil regions. FEBS Lett (2002) 1.50
Endo-siRNAs depend on a new isoform of loquacious and target artificially introduced, high-copy sequences. EMBO J (2009) 1.49
Radixin deficiency causes deafness associated with progressive degeneration of cochlear stereocilia. J Cell Biol (2004) 1.47
Achlorhydria by ezrin knockdown: defects in the formation/expansion of apical canaliculi in gastric parietal cells. J Cell Biol (2005) 1.46
Intravenous calcitriol therapy increases serum concentrations of fibroblast growth factor-23 in dialysis patients with secondary hyperparathyroidism. Nephron Clin Pract (2005) 1.46
SAD: a presynaptic kinase associated with synaptic vesicles and the active zone cytomatrix that regulates neurotransmitter release. Neuron (2006) 1.46
Crystal structure of a claudin provides insight into the architecture of tight junctions. Science (2014) 1.42
Loss of occludin affects tricellular localization of tricellulin. Mol Biol Cell (2008) 1.40
Enrichment and clonal culture of progenitor cells during mouse postnatal liver development in mice. Gastroenterology (2009) 1.39
Activated radixin is essential for GABAA receptor alpha5 subunit anchoring at the actin cytoskeleton. EMBO J (2006) 1.39
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ZO-1- and ZO-2-dependent integration of myosin-2 to epithelial zonula adherens. Mol Biol Cell (2008) 1.36
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The absence of IDO upregulates type I IFN production, resulting in suppression of viral replication in the retrovirus-infected mouse. J Immunol (2010) 1.26
Megaintestine in claudin-15-deficient mice. Gastroenterology (2007) 1.25
Improved myocardial ischemia/reperfusion injury in mice lacking tumor necrosis factor-alpha. J Am Coll Cardiol (2002) 1.25
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EpCAM contributes to formation of functional tight junction in the intestinal epithelium by recruiting claudin proteins. Dev Biol (2012) 1.13
Neural projections in planarian brain revealed by fluorescent dye tracing. Zoolog Sci (2005) 1.13
Lack of tumor necrosis factor receptor type 1 inhibits liver fibrosis induced by carbon tetrachloride in mice. Cytokine (2005) 1.12
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Loss of claudins 2 and 15 from mice causes defects in paracellular Na+ flow and nutrient transport in gut and leads to death from malnutrition. Gastroenterology (2012) 1.09
Aberrant trajectory of ascending dopaminergic pathway in mice lacking Nkx2.1. Exp Neurol (2003) 1.08
PAR3beta, a novel homologue of the cell polarity protein PAR3, localizes to tight junctions. Biochem Biophys Res Commun (2002) 1.07
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Myosin-Va regulates exocytosis through the submicromolar Ca2+-dependent binding of syntaxin-1A. Mol Biol Cell (2005) 1.05
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Trichoplein controls microtubule anchoring at the centrosome by binding to Odf2 and ninein. J Cell Sci (2011) 1.02
Tara up-regulates E-cadherin transcription by binding to the Trio RhoGEF and inhibiting Rac signaling. J Cell Biol (2011) 1.02