Published in Diabetes on May 01, 2006
The role of incretins in glucose homeostasis and diabetes treatment. Pharmacol Rev (2008) 2.73
Mechanisms of action of glucagon-like peptide 1 in the pancreas. Pharmacol Ther (2006) 2.71
Crosstalk in inflammation: the interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatases. Endocr Rev (2009) 1.88
Glucagon-like peptide-1 receptor agonist treatment prevents glucocorticoid-induced glucose intolerance and islet-cell dysfunction in humans. Diabetes Care (2011) 1.10
Calcineurin signaling regulates human islet {beta}-cell survival. J Biol Chem (2010) 1.09
Overexpression of kinase-negative protein kinase Cdelta in pancreatic beta-cells protects mice from diet-induced glucose intolerance and beta-cell dysfunction. Diabetes (2009) 1.07
Is incretin-based therapy ready for the care of hospitalized patients with type 2 diabetes?: The time has come for GLP-1 receptor agonists! Diabetes Care (2013) 1.06
Maternal obesity in ewes results in reduced fetal pancreatic β-cell numbers in late gestation and decreased circulating insulin concentration at term. Domest Anim Endocrinol (2010) 0.98
Tissue-specific actions of glucocorticoids on apoptosis: a double-edged sword. Cells (2013) 0.98
Novel views on new-onset diabetes after transplantation: development, prevention and treatment. Nephrol Dial Transplant (2013) 0.97
Genetics of new-onset diabetes after transplantation. J Am Soc Nephrol (2013) 0.90
Transgenic overexpression of active calcineurin in beta-cells results in decreased beta-cell mass and hyperglycemia. PLoS One (2010) 0.89
Glucocorticoids differentially regulate the expression of CRFR1 and CRFR2α in MIN6 insulinoma cells and rodent islets. Endocrinology (2010) 0.88
The interplay of prolactin and the glucocorticoids in the regulation of beta-cell gene expression, fatty acid oxidation, and glucose-stimulated insulin secretion: implications for carbohydrate metabolism in pregnancy. Endocrinology (2008) 0.87
Reevaluation of fatty acid receptor 1 as a drug target for the stimulation of insulin secretion in humans. Diabetes (2013) 0.87
Liraglutide counteracts obesity and glucose intolerance in a mouse model of glucocorticoid-induced metabolic syndrome. Diabetol Metab Syndr (2014) 0.86
Exenatide improves glucocorticoid-induced glucose intolerance in mice. Diabetes Metab Syndr Obes (2011) 0.85
Increased glucocorticoid receptor expression and activity mediate the LPS resistance of SPRET/EI mice. J Biol Chem (2010) 0.83
Transfection of rat pancreatic islet tissue by polymeric gene vectors. Diabetes Technol Ther (2009) 0.82
Protein kinase C delta (PKCδ) affects proliferation of insulin-secreting cells by promoting nuclear extrusion of the cell cycle inhibitor p21Cip1/WAF1. PLoS One (2011) 0.82
Multi-ligand poly(L-lactic-co-glycolic acid) nanoparticles inhibit activation of endothelial cells. J Cardiovasc Transl Res (2013) 0.81
Type 2 diabetes mellitus and the cardiometabolic syndrome: impact of incretin-based therapies. Diabetes Metab Syndr Obes (2010) 0.81
Peroxisome proliferator-activated receptor activating hypoglycemic effect of Gardenia jasminoides Ellis aqueous extract and improvement of insulin sensitivity in steroid induced insulin resistant rats. BMC Complement Altern Med (2014) 0.81
Regulation of islet beta-cell pyruvate metabolism: interactions of prolactin, glucose, and dexamethasone. Endocrinology (2010) 0.81
Fatty acids do not activate UCP2 in pancreatic beta cells: comparison with UCP1. Pflugers Arch (2008) 0.80
MicroRNAs and Glucocorticoid-Induced Apoptosis in Lymphoid Malignancies. ISRN Hematol (2013) 0.80
Glucocorticoid-induced suppression of β-cell proliferation is mediated by Mig6. Endocrinology (2013) 0.80
What's in a Name? Classification of Diabetes Mellitus in Veterinary Medicine and Why It Matters. J Vet Intern Med (2016) 0.79
Aspirin-Triggered Resolvin D1 Versus Dexamethasone in the Treatment of Sjögren's Syndrome-Like NOD/ShiLtJ Mice - A Pilot Study. J Rheum Dis Treat (2015) 0.78
Protein phosphatases in pancreatic islets. J Endocrinol (2014) 0.77
Ghrelin Protects against Dexamethasone-Induced INS-1 Cell Apoptosis via ERK and p38MAPK Signaling. Int J Endocrinol (2016) 0.77
Nor-1, a novel incretin-responsive regulator of insulin genes and insulin secretion. Mol Metab (2013) 0.77
Decreased 11β-Hydroxysteroid Dehydrogenase 1 Level and Activity in Murine Pancreatic Islets Caused by Insulin-Like Growth Factor I Overexpression. PLoS One (2015) 0.76
Chromosomal mapping of pancreatic islet morphological features and regulatory hormones in the spontaneously diabetic (Type 2) Goto-Kakizaki rat. Mamm Genome (2010) 0.76
Autologous and Allogenous Antibodies in Lung and Islet Cell Transplantation. Front Immunol (2016) 0.75
The impact of hyperglycemia on risk of severe infections during early period of induction therapy in patients with newly diagnosed multiple myeloma. Biomed Res Int (2014) 0.75
Adrenal-Derived Hormones Differentially Modulate Intestinal Immunity in Experimental Colitis. Mediators Inflamm (2016) 0.75
GSK-3β mediates dexamethasone-induced pancreatic β cell apoptosis. Life Sci (2015) 0.75
Exenatide Use in the Management of Type 2 Diabetes Mellitus. Pharmaceuticals (Basel) (2010) 0.75
GLP-1 signalling compensates for impaired insulin signalling in regulating beta cell proliferation in βIRKO mice. Diabetologia (2017) 0.75
Cardiovascular Safety of Antidiabetic Drugs in the Hospital Setting. Curr Diab Rep (2017) 0.75
Use of additives, scaffolds and extracellular matrix components for improvement of human pancreatic islet outcomes in vitro: A systematic review. Islets (2017) 0.75
T-helper-1-cell cytokines drive cancer into senescence. Nature (2013) 4.47
Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis. Nat Med (2008) 3.41
Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3. Biochem J (2004) 3.39
Scientifically unfounded precaution drives European Commission's recommendations on EDC regulation, while defying common sense, well-established science and risk assessment principles. Chem Biol Interact (2013) 3.10
Transient receptor potential M3 channels are ionotropic steroid receptors in pancreatic beta cells. Nat Cell Biol (2008) 2.71
Na(+)-D-glucose cotransporter SGLT1 is pivotal for intestinal glucose absorption and glucose-dependent incretin secretion. Diabetes (2011) 2.65
Impaired renal Na(+) retention in the sgk1-knockout mouse. J Clin Invest (2002) 2.47
Activating mutation of the renal epithelial chloride channel ClC-Kb predisposing to hypertension. Hypertension (2004) 2.32
Liver cell death and anemia in Wilson disease involve acid sphingomyelinase and ceramide. Nat Med (2007) 2.14
Expression and phosphorylation of the Na+-Cl- cotransporter NCC in vivo is regulated by dietary salt, potassium, and SGK1. Am J Physiol Renal Physiol (2009) 2.03
Mechanisms of suicidal erythrocyte death. Cell Physiol Biochem (2005) 2.02
Connective tissue growth factor: a crucial cytokine-mediating cardiac fibrosis in ongoing enterovirus myocarditis. J Mol Med (Berl) (2007) 1.83
KCNQ1-dependent transport in renal and gastrointestinal epithelia. Proc Natl Acad Sci U S A (2005) 1.82
Role of Sgk1 in salt and potassium homeostasis. Am J Physiol Regul Integr Comp Physiol (2005) 1.81
Aldosterone-induced Sgk1 relieves Dot1a-Af9-mediated transcriptional repression of epithelial Na+ channel alpha. J Clin Invest (2007) 1.69
Dynamic adhesion of eryptotic erythrocytes to endothelial cells via CXCL16/SR-PSOX. Am J Physiol Cell Physiol (2011) 1.67
The role of the CO2 laser in the management of laryngotracheal stenosis: a survey of 100 cases. Eur Arch Otorhinolaryngol (2005) 1.67
Comparative analysis of magnetosome gene clusters in magnetotactic bacteria provides further evidence for horizontal gene transfer. Environ Microbiol (2009) 1.66
Spironolactone ameliorates PIT1-dependent vascular osteoinduction in klotho-hypomorphic mice. J Clin Invest (2013) 1.66
Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance. Mol Cell Biol (2008) 1.63
Suicidal death of erythrocytes in recurrent hemolytic uremic syndrome. J Mol Med (Berl) (2006) 1.62
GLUT1 mutations are a cause of paroxysmal exertion-induced dyskinesias and induce hemolytic anemia by a cation leak. J Clin Invest (2008) 1.60
Enhanced glucose tolerance by SK4 channel inhibition in pancreatic beta-cells. Diabetes (2009) 1.58
Blunted DOCA/high salt induced albuminuria and renal tubulointerstitial damage in gene-targeted mice lacking SGK1. J Mol Med (Berl) (2006) 1.55
Regulation of endocytic recycling of KCNQ1/KCNE1 potassium channels. Circ Res (2007) 1.52
Glucocorticoid activation of Na(+)/H(+) exchanger isoform 3 revisited. The roles of SGK1 and NHERF2. J Biol Chem (2001) 1.51
CD83 on dendritic cells: more than just a marker for maturation. Trends Immunol (2002) 1.47
ABCC8 and ABCC9: ABC transporters that regulate K+ channels. Pflugers Arch (2006) 1.47
Electrophysiological studies of malaria parasite-infected erythrocytes: current status. Int J Parasitol (2007) 1.47
Effective T-cell recall responses require the taurine transporter Taut. Eur J Immunol (2012) 1.42
Hyperaldosteronism, hypervolemia, and increased blood pressure in mice expressing defective APC. Am J Physiol Regul Integr Comp Physiol (2009) 1.42
Deregulation of the serum- and glucocorticoid-inducible kinase SGK1 in the endometrium causes reproductive failure. Nat Med (2011) 1.41
Effect of cyclosporine on parasitemia and survival of Plasmodium berghei infected mice. Biochem Biophys Res Commun (2008) 1.41
Decreased bone density and increased phosphaturia in gene-targeted mice lacking functional serum- and glucocorticoid-inducible kinase 3. Kidney Int (2011) 1.40
Plasmodium falciparum activates endogenous Cl(-) channels of human erythrocytes by membrane oxidation. EMBO J (2002) 1.40
Functional analysis of the magnetosome island in Magnetospirillum gryphiswaldense: the mamAB operon is sufficient for magnetite biomineralization. PLoS One (2011) 1.38
Hydration biomarkers in free-living adults with different levels of habitual fluid consumption. Br J Nutr (2012) 1.31
Killing me softly - suicidal erythrocyte death. Int J Biochem Cell Biol (2012) 1.31
High salt reduces the activation of IL-4- and IL-13-stimulated macrophages. J Clin Invest (2015) 1.30
Suicidal erythrocyte death in sepsis. J Mol Med (Berl) (2006) 1.30
Effects of I(Ks) channel inhibitors in insulin-secreting INS-1 cells. Pflugers Arch (2005) 1.29
Role of Ca2+-activated K+ channels in human erythrocyte apoptosis. Am J Physiol Cell Physiol (2003) 1.29
Enhanced programmed cell death of iron-deficient erythrocytes. FASEB J (2005) 1.26
A novel potassium channel in lymphocyte mitochondria. J Biol Chem (2005) 1.26
Discovery of potent and selective agonists for the free fatty acid receptor 1 (FFA(1)/GPR40), a potential target for the treatment of type II diabetes. J Med Chem (2008) 1.25
Erythrocyte programmed cell death. IUBMB Life (2008) 1.25
Chromanol 293B binding in KCNQ1 (Kv7.1) channels involves electrostatic interactions with a potassium ion in the selectivity filter. Mol Pharmacol (2007) 1.24
Serum- and glucocorticoid-inducible kinase 1 (SGK1) mediates glucocorticoid-induced inhibition of insulin secretion. Diabetes (2005) 1.23
Oxidative stress and beta-cell dysfunction. Pflugers Arch (2010) 1.22
Regulation of glucose transporter SGLT1 by ubiquitin ligase Nedd4-2 and kinases SGK1, SGK3, and PKB. Obes Res (2004) 1.21
Impaired regulation of renal K+ elimination in the sgk1-knockout mouse. J Am Soc Nephrol (2004) 1.21
Mitochondrial potassium channel Kv1.3 mediates Bax-induced apoptosis in lymphocytes. Proc Natl Acad Sci U S A (2008) 1.20
mTOR target NDRG1 confers MGMT-dependent resistance to alkylating chemotherapy. Proc Natl Acad Sci U S A (2013) 1.20
Cloning, heterologous expression, and characterization of three aquaglyceroporins from Trypanosoma brucei. J Biol Chem (2004) 1.18
Bile acids acutely stimulate insulin secretion of mouse β-cells via farnesoid X receptor activation and K(ATP) channel inhibition. Diabetes (2012) 1.18
Fenamates as TRP channel blockers: mefenamic acid selectively blocks TRPM3. Br J Pharmacol (2011) 1.18
Yersinia enterocolitica targets cells of the innate and adaptive immune system by injection of Yops in a mouse infection model. PLoS Pathog (2009) 1.16
Phenotype of the taurine transporter knockout mouse. Methods Enzymol (2007) 1.16
Intracellular multiplication of Legionella pneumophila depends on host cell amino acid transporter SLC1A5. Mol Microbiol (2005) 1.16
Serum- and glucocorticoid-inducible kinase 1 (SGK1) controls Notch1 signaling by downregulation of protein stability through Fbw7 ubiquitin ligase. J Cell Sci (2010) 1.15
Electrophysiology of islet cells. Adv Exp Med Biol (2010) 1.14
Evidence for the involvement of Plasmodium falciparum proteins in the formation of new permeability pathways in the erythrocyte membrane. Mol Microbiol (2006) 1.14
The serum and glucocorticoid-inducible kinase SGK1 and the Na+/H+ exchange regulating factor NHERF2 synergize to stimulate the renal outer medullary K+ channel ROMK1. J Am Soc Nephrol (2002) 1.14
Ceramide: physiological and pathophysiological aspects. Arch Biochem Biophys (2007) 1.14
Differential roles of S6 domain hinges in the gating of KCNQ potassium channels. Biophys J (2005) 1.13
cAMP-activated protein kinase-independent potentiation of insulin secretion by cAMP is impaired in SUR1 null islets. Diabetes (2002) 1.12
Targeted disruption of the protein kinase SGK3/CISK impairs postnatal hair follicle development. Mol Biol Cell (2004) 1.11
Modulation of whole-cell currents in Plasmodium falciparum-infected human red blood cells by holding potential and serum. J Physiol (2003) 1.10
The Gq/G11-mediated signaling pathway is critical for autocrine potentiation of insulin secretion in mice. J Clin Invest (2010) 1.10
Characterization of mouse amino acid transporter B0AT1 (slc6a19). Biochem J (2005) 1.10
SGK1-dependent cardiac CTGF formation and fibrosis following DOCA treatment. J Mol Med (Berl) (2006) 1.10
Blunted IgE-mediated activation of mast cells in mice lacking the Ca2+-activated K+ channel KCa3.1. J Immunol (2008) 1.09
The serum- and glucocorticoid-inducible kinase Sgk-1 is involved in pulmonary vascular remodeling: role in redox-sensitive regulation of tissue factor by thrombin. Circ Res (2006) 1.08
Regulation of erythrocyte survival by AMP-activated protein kinase. FASEB J (2008) 1.08
Inhibition of erythrocyte cation channels by erythropoietin. J Am Soc Nephrol (2003) 1.08
Sgk1 activates MDM2-dependent p53 degradation and affects cell proliferation, survival, and differentiation. J Mol Med (Berl) (2009) 1.08
Regulation of the glutamate transporter EAAT1 by the ubiquitin ligase Nedd4-2 and the serum and glucocorticoid-inducible kinase isoforms SGK1/3 and protein kinase B. J Neurochem (2003) 1.08
Blunted hypertensive effect of combined fructose and high-salt diet in gene-targeted mice lacking functional serum- and glucocorticoid-inducible kinase SGK1. Am J Physiol Regul Integr Comp Physiol (2005) 1.07
Overexpression of kinase-negative protein kinase Cdelta in pancreatic beta-cells protects mice from diet-induced glucose intolerance and beta-cell dysfunction. Diabetes (2009) 1.07
Activation of NHE3 by dexamethasone requires phosphorylation of NHE3 at Ser663 by SGK1. Am J Physiol Cell Physiol (2005) 1.07
Protein kinase C activation downregulates human organic anion transporter 1-mediated transport through carrier internalization. J Am Soc Nephrol (2003) 1.06
Modulation of the voltage-gated potassium channel Kv1.5 by the SGK1 protein kinase involves inhibition of channel ubiquitination. Cell Physiol Biochem (2008) 1.06
Post-translational regulation of EAAT2 function by co-expressed ubiquitin ligase Nedd4-2 is impacted by SGK kinases. J Neurochem (2006) 1.06
Mutation of colocalized residues of the pore helix and transmembrane segments S5 and S6 disrupt deactivation and modify inactivation of KCNQ1 K+ channels. J Physiol (2005) 1.05
Suicide for survival--death of infected erythrocytes as a host mechanism to survive malaria. Cell Physiol Biochem (2009) 1.05
Role and regulation of the serum- and glucocorticoid-regulated kinase 1 in fertile and infertile human endometrium. Endocrinology (2007) 1.05
Serum- and glucocorticoid-regulated kinase (SGK1) gene and blood pressure. Hypertension (2002) 1.05
Enhanced insulin sensitivity of gene-targeted mice lacking functional KCNQ1. Am J Physiol Regul Integr Comp Physiol (2009) 1.04
Protein kinase C mediates erythrocyte "programmed cell death" following glucose depletion. Am J Physiol Cell Physiol (2006) 1.04
Functional coassembly of KCNQ4 with KCNE-beta- subunits in Xenopus oocytes. Cell Physiol Biochem (2006) 1.03
SGK1 as a determinant of kidney function and salt intake in response to mineralocorticoid excess. Am J Physiol Regul Integr Comp Physiol (2005) 1.03
Identification of a potent and selective free fatty acid receptor 1 (FFA1/GPR40) agonist with favorable physicochemical and in vitro ADME properties. J Med Chem (2011) 1.03