Scientifically unfounded precaution drives European Commission's recommendations on EDC regulation, while defying common sense, well-established science and risk assessment principles.

PubWeight™: 1.38‹?› | Rank: Top 10%

🔗 View Article (PMID 24409469)

Published in Toxicon on December 15, 2013

Authors

Daniel R Dietrich, Sonja von Aulock, Hans Marquardt, Bas Blaauboer, Wolfgang Dekant, James Kehrer, Jan Hengstler, Abby Collier, Gio Batta Gori, Olavi Pelkonen, Florian Lang, Frans P Nijkamp, Kerstin Stemmer, Albert Li, Kai Savolainen, A Wallace Hayes, Nigel Gooderham, Alan Harvey, Frank A Barile

Articles by these authors

A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation. Nat Med (2006) 5.05

Metabolism and kinetics of bisphenol a in humans at low doses following oral administration. Chem Res Toxicol (2002) 4.52

Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis. Nat Med (2008) 3.41

Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3. Biochem J (2004) 3.39

Commensal bacteria regulate Toll-like receptor 3-dependent inflammation after skin injury. Nat Med (2009) 3.32

Scientifically unfounded precaution drives European Commission's recommendations on EDC regulation, while defying common sense, well-established science and risk assessment principles. Chem Biol Interact (2013) 3.10

Na(+)-D-glucose cotransporter SGLT1 is pivotal for intestinal glucose absorption and glucose-dependent incretin secretion. Diabetes (2011) 2.65

Impaired renal Na(+) retention in the sgk1-knockout mouse. J Clin Invest (2002) 2.47

Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework. Toxicol Appl Pharmacol (2007) 2.37

Activating mutation of the renal epithelial chloride channel ClC-Kb predisposing to hypertension. Hypertension (2004) 2.32

Liver cell death and anemia in Wilson disease involve acid sphingomyelinase and ceramide. Nat Med (2007) 2.14

Issues in the design and interpretation of chronic toxicity and carcinogenicity studies in rodents: approaches to dose selection. Crit Rev Toxicol (2007) 2.05

Expression and phosphorylation of the Na+-Cl- cotransporter NCC in vivo is regulated by dietary salt, potassium, and SGK1. Am J Physiol Renal Physiol (2009) 2.03

Mechanisms of suicidal erythrocyte death. Cell Physiol Biochem (2005) 2.02

Connective tissue growth factor: a crucial cytokine-mediating cardiac fibrosis in ongoing enterovirus myocarditis. J Mol Med (Berl) (2007) 1.83

KCNQ1-dependent transport in renal and gastrointestinal epithelia. Proc Natl Acad Sci U S A (2005) 1.82

Role of Sgk1 in salt and potassium homeostasis. Am J Physiol Regul Integr Comp Physiol (2005) 1.81

Immunoglobulin-free light chains elicit immediate hypersensitivity-like responses. Nat Med (2002) 1.73

Aldosterone-induced Sgk1 relieves Dot1a-Af9-mediated transcriptional repression of epithelial Na+ channel alpha. J Clin Invest (2007) 1.69

Dynamic adhesion of eryptotic erythrocytes to endothelial cells via CXCL16/SR-PSOX. Am J Physiol Cell Physiol (2011) 1.67

The role of the CO2 laser in the management of laryngotracheal stenosis: a survey of 100 cases. Eur Arch Otorhinolaryngol (2005) 1.67

Spironolactone ameliorates PIT1-dependent vascular osteoinduction in klotho-hypomorphic mice. J Clin Invest (2013) 1.66

Repeatability of sodium and chloride in exhaled breath condensates. Pediatr Pulmonol (2004) 1.63

Endocrine effects of tetrabromobisphenol-A (TBBPA) in Wistar rats as tested in a one-generation reproduction study and a subacute toxicity study. Toxicology (2007) 1.63

Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance. Mol Cell Biol (2008) 1.63

Suicidal death of erythrocytes in recurrent hemolytic uremic syndrome. J Mol Med (Berl) (2006) 1.62

Long, needle-like carbon nanotubes and asbestos activate the NLRP3 inflammasome through a similar mechanism. ACS Nano (2011) 1.62

Cellular trafficking of lipoteichoic acid and Toll-like receptor 2 in relation to signaling: role of CD14 and CD36. J Leukoc Biol (2008) 1.61

Quantitation of bisphenol A and bisphenol A glucuronide in biological samples by high performance liquid chromatography-tandem mass spectrometry. Drug Metab Dispos (2005) 1.60

GLUT1 mutations are a cause of paroxysmal exertion-induced dyskinesias and induce hemolytic anemia by a cation leak. J Clin Invest (2008) 1.60

Protein expression and peptide binding suggest unique and interacting functional roles for HLA-E, F, and G in maternal-placental immune recognition. J Immunol (2003) 1.60

Absence of 2'-deoxyguanosine-carbon 8-bound ochratoxin A adduct in rat kidney DNA monitored by isotope dilution LC-MS/MS. Mol Nutr Food Res (2008) 1.56

Blunted DOCA/high salt induced albuminuria and renal tubulointerstitial damage in gene-targeted mice lacking SGK1. J Mol Med (Berl) (2006) 1.55

Activation of coagulation and inhibition of fibrinolysis in the human lung on bronchial instillation of lipoteichoic acid and lipopolysaccharide. Crit Care Med (2009) 1.55

IL-33 enhances lipopolysaccharide-induced inflammatory cytokine production from mouse macrophages by regulating lipopolysaccharide receptor complex. J Immunol (2009) 1.54

Impaired glucose tolerance in rats fed low-carbohydrate, high-fat diets. Am J Physiol Endocrinol Metab (2013) 1.54

Regulation of endocytic recycling of KCNQ1/KCNE1 potassium channels. Circ Res (2007) 1.52

Targeted estrogen delivery reverses the metabolic syndrome. Nat Med (2012) 1.51

Glucocorticoid activation of Na(+)/H(+) exchanger isoform 3 revisited. The roles of SGK1 and NHERF2. J Biol Chem (2001) 1.51

Electrophysiological studies of malaria parasite-infected erythrocytes: current status. Int J Parasitol (2007) 1.47

Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010. Arch Toxicol (2011) 1.46

Bone marrow depletion with haemorrhagic diathesis in calves in Germany: characterization of the disease and preliminary investigations on its aetiology. Berl Munch Tierarztl Wochenschr (2010) 1.45

Sharpening the focus on occupational safety and health in nanotechnology. Scand J Work Environ Health (2008) 1.44

Effective T-cell recall responses require the taurine transporter Taut. Eur J Immunol (2012) 1.42

Hyperaldosteronism, hypervolemia, and increased blood pressure in mice expressing defective APC. Am J Physiol Regul Integr Comp Physiol (2009) 1.42

Deregulation of the serum- and glucocorticoid-inducible kinase SGK1 in the endometrium causes reproductive failure. Nat Med (2011) 1.41

Effect of cyclosporine on parasitemia and survival of Plasmodium berghei infected mice. Biochem Biophys Res Commun (2008) 1.41

Decreased bone density and increased phosphaturia in gene-targeted mice lacking functional serum- and glucocorticoid-inducible kinase 3. Kidney Int (2011) 1.40

Plasmodium falciparum activates endogenous Cl(-) channels of human erythrocytes by membrane oxidation. EMBO J (2002) 1.40

Ochratoxin A: the continuing enigma. Crit Rev Toxicol (2005) 1.39

Dimensional errors of metaphorical measurements. Can they be resolved? Int J Epidemiol (2006) 1.39

Dexamethasone induces cell death in insulin-secreting cells, an effect reversed by exendin-4. Diabetes (2006) 1.35

Hydration biomarkers in free-living adults with different levels of habitual fluid consumption. Br J Nutr (2012) 1.31

Killing me softly - suicidal erythrocyte death. Int J Biochem Cell Biol (2012) 1.31

High salt reduces the activation of IL-4- and IL-13-stimulated macrophages. J Clin Invest (2015) 1.30

Suicidal erythrocyte death in sepsis. J Mol Med (Berl) (2006) 1.30

Airway exposure to silica-coated TiO2 nanoparticles induces pulmonary neutrophilia in mice. Toxicol Sci (2009) 1.30

Effects of I(Ks) channel inhibitors in insulin-secreting INS-1 cells. Pflugers Arch (2005) 1.29

Role of Ca2+-activated K+ channels in human erythrocyte apoptosis. Am J Physiol Cell Physiol (2003) 1.29

Occupational exposure to inhalable wood dust in the member states of the European Union. Ann Occup Hyg (2006) 1.29

Expression and regulation of xenobiotic-metabolizing cytochrome P450 (CYP) enzymes in human lung. Crit Rev Toxicol (2002) 1.28

Inflammatory changes in the airways of mice caused by cigarette smoke exposure are only partially reversed after smoking cessation. Respir Res (2010) 1.27

Induction of lung emphysema is prevented by L-arginine-threonine-arginine. FASEB J (2008) 1.27

Bovine TLR2 and TLR4 properly transduce signals from Staphylococcus aureus and E. coli, but S. aureus fails to both activate NF-kappaB in mammary epithelial cells and to quickly induce TNFalpha and interleukin-8 (CXCL8) expression in the udder. Mol Immunol (2007) 1.27

HER-2/neu-mediated regulation of components of the MHC class I antigen-processing pathway. Cancer Res (2004) 1.26

Enhanced programmed cell death of iron-deficient erythrocytes. FASEB J (2005) 1.26

A novel potassium channel in lymphocyte mitochondria. J Biol Chem (2005) 1.26

Erythrocyte programmed cell death. IUBMB Life (2008) 1.25

Chromanol 293B binding in KCNQ1 (Kv7.1) channels involves electrostatic interactions with a potassium ion in the selectivity filter. Mol Pharmacol (2007) 1.24

Proteomic characterization of engineered nanomaterial-protein interactions in relation to surface reactivity. ACS Nano (2011) 1.24

Serum- and glucocorticoid-inducible kinase 1 (SGK1) mediates glucocorticoid-induced inhibition of insulin secretion. Diabetes (2005) 1.23

Effect of clopidogrel and ticlopidine on cytochrome P450 2B6 activity as measured by bupropion hydroxylation. Clin Pharmacol Ther (2005) 1.22

Lipoteichoic acid-induced lung inflammation depends on TLR2 and the concerted action of TLR4 and the platelet-activating factor receptor. J Immunol (2008) 1.22

Regulation of glucose transporter SGLT1 by ubiquitin ligase Nedd4-2 and kinases SGK1, SGK3, and PKB. Obes Res (2004) 1.21

Impaired regulation of renal K+ elimination in the sgk1-knockout mouse. J Am Soc Nephrol (2004) 1.21

Fibroblast growth factor 21 mediates specific glucagon actions. Diabetes (2013) 1.20

Toll-like receptor-4 mediates cigarette smoke-induced cytokine production by human macrophages. Respir Res (2006) 1.20

Tailored interventions based on exhaled nitric oxide versus clinical symptoms for asthma in children and adults. Cochrane Database Syst Rev (2009) 1.20

Mitochondrial potassium channel Kv1.3 mediates Bax-induced apoptosis in lymphocytes. Proc Natl Acad Sci U S A (2008) 1.20

mTOR target NDRG1 confers MGMT-dependent resistance to alkylating chemotherapy. Proc Natl Acad Sci U S A (2013) 1.20

Schizophrenia and sudden cardiac death: a review. Nord J Psychiatry (2008) 1.19

Comparative analysis of novel noninvasive renal biomarkers and metabonomic changes in a rat model of gentamicin nephrotoxicity. Toxicol Sci (2009) 1.18