Published in J Biol Chem on December 21, 2001
NHERF family and NHE3 regulation. J Physiol (2005) 1.81
Regulation of NHE3 by lysophosphatidic acid is mediated by phosphorylation of NHE3 by RSK2. Am J Physiol Cell Physiol (2015) 1.44
NHERF2 specifically interacts with LPA2 receptor and defines the specificity and efficiency of receptor-mediated phospholipase C-beta3 activation. Mol Cell Biol (2004) 1.37
The physiological impact of the serum and glucocorticoid-inducible kinase SGK1. Curr Opin Nephrol Hypertens (2009) 1.35
Lysophosphatidic acid stimulates the intestinal brush border Na(+)/H(+) exchanger 3 and fluid absorption via LPA(5) and NHERF2. Gastroenterology (2009) 1.33
Colonic gene expression profile in NHE3-deficient mice: evidence for spontaneous distal colitis. Am J Physiol Gastrointest Liver Physiol (2008) 1.32
Glucocorticoids acutely increase cell surface Na+/H+ exchanger-3 (NHE3) by activation of NHE3 exocytosis. Am J Physiol Renal Physiol (2005) 1.31
Lysophosphatidic acid facilitates proliferation of colon cancer cells via induction of Krüppel-like factor 5. J Biol Chem (2007) 1.29
Regulation of electroneutral NaCl absorption by the small intestine. Annu Rev Physiol (2011) 1.15
Crystal structure of the kinase domain of serum and glucocorticoid-regulated kinase 1 in complex with AMP PNP. Protein Sci (2007) 1.11
IRBIT, inositol 1,4,5-triphosphate (IP3) receptor-binding protein released with IP3, binds Na+/H+ exchanger NHE3 and activates NHE3 activity in response to calcium. J Biol Chem (2008) 1.09
NHERF1 and NHERF2 are necessary for multiple but usually separate aspects of basal and acute regulation of NHE3 activity. Am J Physiol Cell Physiol (2010) 1.09
Changes in mucosal homeostasis predispose NHE3 knockout mice to increased susceptibility to DSS-induced epithelial injury. Gastroenterology (2009) 1.08
MAGI-3 regulates LPA-induced activation of Erk and RhoA. Cell Signal (2006) 1.07
Activation of NHE3 by dexamethasone requires phosphorylation of NHE3 at Ser663 by SGK1. Am J Physiol Cell Physiol (2005) 1.07
Characterization of the regulation of renal Na+/H+ exchanger NHE3 by insulin. Am J Physiol Renal Physiol (2006) 1.04
Mechanisms of the regulation of the intestinal Na+/H+ exchanger NHE3. J Biomed Biotechnol (2010) 1.02
The organic anion transporter (OAT) family: a systems biology perspective. Physiol Rev (2015) 1.01
FGF23 acts directly on renal proximal tubules to induce phosphaturia through activation of the ERK1/2-SGK1 signaling pathway. Bone (2012) 0.99
Acute activation of NHE3 by dexamethasone correlates with activation of SGK1 and requires a functional glucocorticoid receptor. Am J Physiol Cell Physiol (2006) 0.97
Serum- and glucocorticoid-induced kinase 3 in recycling endosomes mediates acute activation of Na+/H+ exchanger NHE3 by glucocorticoids. Mol Biol Cell (2011) 0.95
Na+-H+ exchanger regulatory factor 1 is a PDZ scaffold for the astroglial glutamate transporter GLAST. Glia (2007) 0.91
Human intestinal epithelial cell line SK-CO15 is a new model system to study Na(+)/H(+) exchanger 3. Am J Physiol Gastrointest Liver Physiol (2012) 0.90
SGK1 increases Na,K-ATP cell-surface expression and function in Xenopus laevis oocytes. Pflugers Arch (2004) 0.90
SGK1-sensitive renal tubular glucose reabsorption in diabetes. Am J Physiol Renal Physiol (2009) 0.88
Role of the epithelial sodium channel in salt-sensitive hypertension. Acta Pharmacol Sin (2011) 0.88
Concerted roles of SGK1 and the Na+/H+ exchanger regulatory factor 2 (NHERF2) in regulation of NHE3. Cell Physiol Biochem (2003) 0.87
Expression and role of serum and glucocorticoid-regulated kinase 2 in the regulation of Na+/H+ exchanger 3 in the mammalian kidney. Am J Physiol Renal Physiol (2010) 0.87
NHERF2 protein mobility rate is determined by a unique C-terminal domain that is also necessary for its regulation of NHE3 protein in OK cells. J Biol Chem (2013) 0.85
Coexpression of MAST205 inhibits the activity of Na+/H+ exchanger NHE3. Am J Physiol Renal Physiol (2005) 0.85
Scaffold protein connector enhancer of kinase suppressor of Ras isoform 3 (CNK3) coordinates assembly of a multiprotein epithelial sodium channel (ENaC)-regulatory complex. J Biol Chem (2012) 0.85
Regulation of intracellular pH by p90Rsk-dependent activation of an Na(+)/H(+) exchanger in starfish oocytes. J Biol Chem (2010) 0.85
Renal tubular transport and the genetic basis of hypertensive disease. Clin Exp Nephrol (2005) 0.85
Developmental changes in proximal tubule NaCl transport. Pediatr Nephrol (2007) 0.84
The role of the ENaC-regulatory complex in aldosterone-mediated sodium transport. Mol Cell Endocrinol (2011) 0.84
Decreased intestinal glucose transport in the sgk3-knockout mouse. Pflugers Arch (2005) 0.83
Role of the serum and glucocorticoid inducible kinase SGK1 in glucocorticoid stimulation of gastric acid secretion. Pflugers Arch (2007) 0.81
Uncovering the salt response of soybean by unraveling its wild and cultivated functional genomes using tag sequencing. PLoS One (2012) 0.81
NHERF2/NHERF3 protein heterodimerization and macrocomplex formation are required for the inhibition of NHE3 activity by carbachol. J Biol Chem (2014) 0.80
Dopamine regulation of Na+-K+-ATPase requires the PDZ-2 domain of sodium hydrogen regulatory factor-1 (NHERF-1) in opossum kidney cells. Am J Physiol Cell Physiol (2010) 0.80
Serum- and glucocorticoid-induced protein kinase 1 (SGK1) is regulated by store-operated Ca2+ entry and mediates cytoprotection against necrotic cell death. J Biol Chem (2013) 0.80
Time-course changes of steroidogenic gene expression and steroidogenesis of rat Leydig cells after acute immobilization stress. Int J Mol Sci (2014) 0.80
Chloride channel (Clc)-5 is necessary for exocytic trafficking of Na+/H+ exchanger 3 (NHE3). J Biol Chem (2011) 0.79
Serum- and glucocorticoid-inducible kinase 1 in the regulation of renal and extrarenal potassium transport. Clin Exp Nephrol (2011) 0.79
AKT and GSK-3 are necessary for direct ezrin binding to NHE3 as part of a C-terminal stimulatory complex: role of a novel Ser-rich NHE3 C-terminal motif in NHE3 activity and trafficking. J Biol Chem (2014) 0.79
Alterations in the proteome of the NHERF2 knockout mouse jejunal brush border membrane vesicles. Physiol Genomics (2011) 0.78
Nonsynonymous single nucleotide polymorphisms of NHE3 differentially decrease NHE3 transporter activity. Am J Physiol Cell Physiol (2015) 0.78
Tumor suppressor gene adenomatous polyposis coli downregulates intestinal transport. Pflugers Arch (2011) 0.78
Stimulation of electrogenic intestinal dipeptide transport by the glucocorticoid dexamethasone. Pflugers Arch (2009) 0.78
Unique regulation of human Na+/H+ exchanger 3 (NHE3) by Nedd4-2 ligase that differs from non-primate NHE3s. J Biol Chem (2014) 0.77
Glucocorticoids Reduce Renal NHE8 Expression. Physiol Rep (2013) 0.77
Concerted actions of NHERF2 and WNK4 in regulating TRPV5. Biochem Biophys Res Commun (2010) 0.77
Postnatal developmental expression of the PDZ scaffolds Na+ -H+ exchanger regulatory factors 1 and 2 in the rat cochlea. Cell Tissue Res (2005) 0.77
SGK1 dependence of insulin induced hypokalemia. Pflugers Arch (2008) 0.77
Deletion of Na+/H+ exchanger regulatory factor 2 represses colon cancer progress by suppression of Stat3 and CD24. Am J Physiol Gastrointest Liver Physiol (2016) 0.76
The NHERF2 sequence adjacent and upstream of the ERM-binding domain affects NHERF2-ezrin binding and dexamethasone stimulated NHE3 activity. Biochem J (2015) 0.75
Antisecretory factor peptide AF-16 inhibits the secreted autotransporter toxin-stimulated transcellular and paracellular passages of fluid in cultured human enterocyte-like cells. Infect Immun (2014) 0.75
Network and Pathway-Based Analyses of Genes Associated with Parkinson's Disease. Mol Neurobiol (2016) 0.75
Group II metabotropic glutamate receptor interactions with NHERF scaffold proteins: Implications for receptor localization in brain. Neuroscience (2017) 0.75
Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis. Nat Med (2008) 3.41
Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3. Biochem J (2004) 3.39
Scientifically unfounded precaution drives European Commission's recommendations on EDC regulation, while defying common sense, well-established science and risk assessment principles. Chem Biol Interact (2013) 3.10
Na(+)-D-glucose cotransporter SGLT1 is pivotal for intestinal glucose absorption and glucose-dependent incretin secretion. Diabetes (2011) 2.65
Impaired renal Na(+) retention in the sgk1-knockout mouse. J Clin Invest (2002) 2.47
Activating mutation of the renal epithelial chloride channel ClC-Kb predisposing to hypertension. Hypertension (2004) 2.32
Liver cell death and anemia in Wilson disease involve acid sphingomyelinase and ceramide. Nat Med (2007) 2.14
Expression and phosphorylation of the Na+-Cl- cotransporter NCC in vivo is regulated by dietary salt, potassium, and SGK1. Am J Physiol Renal Physiol (2009) 2.03
Mechanisms of suicidal erythrocyte death. Cell Physiol Biochem (2005) 2.02
Systematic review of patellar resurfacing in total knee arthroplasty. Int Orthop (2010) 1.84
Connective tissue growth factor: a crucial cytokine-mediating cardiac fibrosis in ongoing enterovirus myocarditis. J Mol Med (Berl) (2007) 1.83
KCNQ1-dependent transport in renal and gastrointestinal epithelia. Proc Natl Acad Sci U S A (2005) 1.82
Role of Sgk1 in salt and potassium homeostasis. Am J Physiol Regul Integr Comp Physiol (2005) 1.81
Aldosterone-induced Sgk1 relieves Dot1a-Af9-mediated transcriptional repression of epithelial Na+ channel alpha. J Clin Invest (2007) 1.69
Dynamic adhesion of eryptotic erythrocytes to endothelial cells via CXCL16/SR-PSOX. Am J Physiol Cell Physiol (2011) 1.67
The role of the CO2 laser in the management of laryngotracheal stenosis: a survey of 100 cases. Eur Arch Otorhinolaryngol (2005) 1.67
Spironolactone ameliorates PIT1-dependent vascular osteoinduction in klotho-hypomorphic mice. J Clin Invest (2013) 1.66
Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance. Mol Cell Biol (2008) 1.63
Suicidal death of erythrocytes in recurrent hemolytic uremic syndrome. J Mol Med (Berl) (2006) 1.62
GLUT1 mutations are a cause of paroxysmal exertion-induced dyskinesias and induce hemolytic anemia by a cation leak. J Clin Invest (2008) 1.60
Blunted DOCA/high salt induced albuminuria and renal tubulointerstitial damage in gene-targeted mice lacking SGK1. J Mol Med (Berl) (2006) 1.55
Regulation of endocytic recycling of KCNQ1/KCNE1 potassium channels. Circ Res (2007) 1.52
Electrophysiological studies of malaria parasite-infected erythrocytes: current status. Int J Parasitol (2007) 1.47
Effective T-cell recall responses require the taurine transporter Taut. Eur J Immunol (2012) 1.42
Hyperaldosteronism, hypervolemia, and increased blood pressure in mice expressing defective APC. Am J Physiol Regul Integr Comp Physiol (2009) 1.42
Deregulation of the serum- and glucocorticoid-inducible kinase SGK1 in the endometrium causes reproductive failure. Nat Med (2011) 1.41
Effect of cyclosporine on parasitemia and survival of Plasmodium berghei infected mice. Biochem Biophys Res Commun (2008) 1.41
Decreased bone density and increased phosphaturia in gene-targeted mice lacking functional serum- and glucocorticoid-inducible kinase 3. Kidney Int (2011) 1.40
Plasmodium falciparum activates endogenous Cl(-) channels of human erythrocytes by membrane oxidation. EMBO J (2002) 1.40
Dexamethasone induces cell death in insulin-secreting cells, an effect reversed by exendin-4. Diabetes (2006) 1.35
Hydration biomarkers in free-living adults with different levels of habitual fluid consumption. Br J Nutr (2012) 1.31
Killing me softly - suicidal erythrocyte death. Int J Biochem Cell Biol (2012) 1.31
High salt reduces the activation of IL-4- and IL-13-stimulated macrophages. J Clin Invest (2015) 1.30
Suicidal erythrocyte death in sepsis. J Mol Med (Berl) (2006) 1.30
Effects of I(Ks) channel inhibitors in insulin-secreting INS-1 cells. Pflugers Arch (2005) 1.29
Role of Ca2+-activated K+ channels in human erythrocyte apoptosis. Am J Physiol Cell Physiol (2003) 1.29
Carbachol regulation of rabbit ileal brush border Na+-H+ exchanger 3 (NHE3) occurs through changes in NHE3 trafficking and complex formation and is Src dependent. J Physiol (2004) 1.27
Enhanced programmed cell death of iron-deficient erythrocytes. FASEB J (2005) 1.26
Downregulation of sodium transporters and NHERF proteins in IBD patients and mouse colitis models: potential contributors to IBD-associated diarrhea. Inflamm Bowel Dis (2009) 1.26
A novel potassium channel in lymphocyte mitochondria. J Biol Chem (2005) 1.26
Erythrocyte programmed cell death. IUBMB Life (2008) 1.25
Chromanol 293B binding in KCNQ1 (Kv7.1) channels involves electrostatic interactions with a potassium ion in the selectivity filter. Mol Pharmacol (2007) 1.24
Serum- and glucocorticoid-inducible kinase 1 (SGK1) mediates glucocorticoid-induced inhibition of insulin secretion. Diabetes (2005) 1.23
Regulation of glucose transporter SGLT1 by ubiquitin ligase Nedd4-2 and kinases SGK1, SGK3, and PKB. Obes Res (2004) 1.21
Impaired regulation of renal K+ elimination in the sgk1-knockout mouse. J Am Soc Nephrol (2004) 1.21
Mitochondrial potassium channel Kv1.3 mediates Bax-induced apoptosis in lymphocytes. Proc Natl Acad Sci U S A (2008) 1.20
mTOR target NDRG1 confers MGMT-dependent resistance to alkylating chemotherapy. Proc Natl Acad Sci U S A (2013) 1.20
Cloning, heterologous expression, and characterization of three aquaglyceroporins from Trypanosoma brucei. J Biol Chem (2004) 1.18
Phenotype of the taurine transporter knockout mouse. Methods Enzymol (2007) 1.16
Intracellular multiplication of Legionella pneumophila depends on host cell amino acid transporter SLC1A5. Mol Microbiol (2005) 1.16
Serum- and glucocorticoid-inducible kinase 1 (SGK1) controls Notch1 signaling by downregulation of protein stability through Fbw7 ubiquitin ligase. J Cell Sci (2010) 1.15
Evidence for the involvement of Plasmodium falciparum proteins in the formation of new permeability pathways in the erythrocyte membrane. Mol Microbiol (2006) 1.14
The serum and glucocorticoid-inducible kinase SGK1 and the Na+/H+ exchange regulating factor NHERF2 synergize to stimulate the renal outer medullary K+ channel ROMK1. J Am Soc Nephrol (2002) 1.14
Ceramide: physiological and pathophysiological aspects. Arch Biochem Biophys (2007) 1.14
Differential roles of S6 domain hinges in the gating of KCNQ potassium channels. Biophys J (2005) 1.13
Targeted disruption of the protein kinase SGK3/CISK impairs postnatal hair follicle development. Mol Biol Cell (2004) 1.11
Casein kinase 2 binds to the C terminus of Na+/H+ exchanger 3 (NHE3) and stimulates NHE3 basal activity by phosphorylating a separate site in NHE3. Mol Biol Cell (2008) 1.10
Modulation of whole-cell currents in Plasmodium falciparum-infected human red blood cells by holding potential and serum. J Physiol (2003) 1.10
Characterization of mouse amino acid transporter B0AT1 (slc6a19). Biochem J (2005) 1.10
SGK1-dependent cardiac CTGF formation and fibrosis following DOCA treatment. J Mol Med (Berl) (2006) 1.10
Blunted IgE-mediated activation of mast cells in mice lacking the Ca2+-activated K+ channel KCa3.1. J Immunol (2008) 1.09
Regulation of erythrocyte survival by AMP-activated protein kinase. FASEB J (2008) 1.08
Inhibition of erythrocyte cation channels by erythropoietin. J Am Soc Nephrol (2003) 1.08
The serum- and glucocorticoid-inducible kinase Sgk-1 is involved in pulmonary vascular remodeling: role in redox-sensitive regulation of tissue factor by thrombin. Circ Res (2006) 1.08
Sgk1 activates MDM2-dependent p53 degradation and affects cell proliferation, survival, and differentiation. J Mol Med (Berl) (2009) 1.08
Regulation of the glutamate transporter EAAT1 by the ubiquitin ligase Nedd4-2 and the serum and glucocorticoid-inducible kinase isoforms SGK1/3 and protein kinase B. J Neurochem (2003) 1.08
Blunted hypertensive effect of combined fructose and high-salt diet in gene-targeted mice lacking functional serum- and glucocorticoid-inducible kinase SGK1. Am J Physiol Regul Integr Comp Physiol (2005) 1.07
Activation of NHE3 by dexamethasone requires phosphorylation of NHE3 at Ser663 by SGK1. Am J Physiol Cell Physiol (2005) 1.07
Protein kinase C activation downregulates human organic anion transporter 1-mediated transport through carrier internalization. J Am Soc Nephrol (2003) 1.06
Post-translational regulation of EAAT2 function by co-expressed ubiquitin ligase Nedd4-2 is impacted by SGK kinases. J Neurochem (2006) 1.06
Modulation of the voltage-gated potassium channel Kv1.5 by the SGK1 protein kinase involves inhibition of channel ubiquitination. Cell Physiol Biochem (2008) 1.06
Mutation of colocalized residues of the pore helix and transmembrane segments S5 and S6 disrupt deactivation and modify inactivation of KCNQ1 K+ channels. J Physiol (2005) 1.05
Serum- and glucocorticoid-regulated kinase (SGK1) gene and blood pressure. Hypertension (2002) 1.05
Suicide for survival--death of infected erythrocytes as a host mechanism to survive malaria. Cell Physiol Biochem (2009) 1.05
Role and regulation of the serum- and glucocorticoid-regulated kinase 1 in fertile and infertile human endometrium. Endocrinology (2007) 1.05
Enhanced insulin sensitivity of gene-targeted mice lacking functional KCNQ1. Am J Physiol Regul Integr Comp Physiol (2009) 1.04
Protein kinase C mediates erythrocyte "programmed cell death" following glucose depletion. Am J Physiol Cell Physiol (2006) 1.04
Functional coassembly of KCNQ4 with KCNE-beta- subunits in Xenopus oocytes. Cell Physiol Biochem (2006) 1.03
SGK1 as a determinant of kidney function and salt intake in response to mineralocorticoid excess. Am J Physiol Regul Integr Comp Physiol (2005) 1.03
Serum- and glucocorticoid-regulated kinase 1 is upregulated following unilateral ureteral obstruction causing epithelial-mesenchymal transition. Kidney Int (2010) 1.02
Accelerated clearance of Plasmodium-infected erythrocytes in sickle cell trait and annexin-A7 deficiency. Cell Physiol Biochem (2009) 1.02
Surgical management of laryngotracheal stenosis in adults. Eur Arch Otorhinolaryngol (2005) 1.02
Disrupting the EMMPRIN (CD147)-cyclophilin A interaction reduces infarct size and preserves systolic function after myocardial ischemia and reperfusion. Arterioscler Thromb Vasc Biol (2011) 1.02
Membrane androgen receptor activation triggers down-regulation of PI-3K/Akt/NF-kappaB activity and induces apoptotic responses via Bad, FasL and caspase-3 in DU145 prostate cancer cells. Mol Cancer (2008) 1.01
Negative regulation of SEK1 signaling by serum- and glucocorticoid-inducible protein kinase 1. EMBO J (2007) 1.01
Ion channels modulating mouse dendritic cell functions. J Immunol (2008) 1.01
Cystinuria in children: distribution and frequencies of mutations in the SLC3A1 and SLC7A9 genes. Kidney Int (2002) 1.01
Serum and glucocorticoid inducible kinases in the regulation of the cardiac sodium channel SCN5A. Cardiovasc Res (2003) 1.01
Regulation of the glutamine transporter SN1 by extracellular pH and intracellular sodium ions. J Physiol (2002) 1.01
Anemia and splenomegaly in cGKI-deficient mice. Proc Natl Acad Sci U S A (2008) 1.00
Purinoceptors are involved in the induction of an osmolyte permeability in malaria-infected and oxidized human erythrocytes. FASEB J (2005) 1.00
Methods employed for induction and analysis of experimental myocardial infarction in mice. Cell Physiol Biochem (2011) 1.00
Oxidation induces a Cl(-)-dependent cation conductance in human red blood cells. J Physiol (2002) 1.00
Scientifically unfounded precaution drives European Commission's recommendations on EDC regulation, while defying common sense, well-established science and risk assessment principles. Food Chem Toxicol (2013) 1.00
The impact of erythrocyte age on eryptosis. Br J Haematol (2012) 1.00
TRPC6 contributes to the Ca(2+) leak of human erythrocytes. Cell Physiol Biochem (2008) 0.99
Proteome analysis of erythrocytes lacking AMP-activated protein kinase reveals a role of PAK2 kinase in eryptosis. J Proteome Res (2011) 0.98
New insights into the role of serum- and glucocorticoid-inducible kinase SGK1 in the regulation of renal function and blood pressure. Curr Opin Nephrol Hypertens (2005) 0.98