Published in Mol Endocrinol on April 27, 2006
Crosstalk between the estrogen receptor and the HER tyrosine kinase receptor family: molecular mechanism and clinical implications for endocrine therapy resistance. Endocr Rev (2008) 3.13
Vascular actions of estrogens: functional implications. Pharmacol Rev (2008) 2.52
Uncovering the mechanisms of estrogen effects on hippocampal function. Front Neuroendocrinol (2007) 2.13
Phosphatidylinositol 3-kinase and antiestrogen resistance in breast cancer. J Clin Oncol (2011) 2.10
Nuclear and extranuclear pathway inputs in the regulation of global gene expression by estrogen receptors. Mol Endocrinol (2008) 2.09
CAR and PXR: the xenobiotic-sensing receptors. Steroids (2006) 2.06
Estrogen receptor beta: an overview and update. Nucl Recept Signal (2008) 1.97
Non-nuclear estrogen receptor alpha signaling promotes cardiovascular protection but not uterine or breast cancer growth in mice. J Clin Invest (2010) 1.90
Plasma membrane estrogen receptors. Trends Endocrinol Metab (2009) 1.85
Involvement of estrogen receptor variant ER-alpha36, not GPR30, in nongenomic estrogen signaling. Mol Endocrinol (2010) 1.77
Estrogen regulation of apoptosis: how can one hormone stimulate and inhibit? Breast Cancer Res (2009) 1.75
Estradiol induces export of sphingosine 1-phosphate from breast cancer cells via ABCC1 and ABCG2. J Biol Chem (2010) 1.74
Involvement of G protein-coupled receptor 30 (GPR30) in rapid action of estrogen in primate LHRH neurons. Mol Endocrinol (2009) 1.72
Sex differences in the regulation of body weight. Physiol Behav (2009) 1.68
Mechanisms of primary and secondary estrogen target gene regulation in breast cancer cells. Nucleic Acids Res (2007) 1.63
Minireview: rapid glucocorticoid signaling via membrane-associated receptors. Endocrinology (2006) 1.58
Developmental phenotype of a membrane only estrogen receptor alpha (MOER) mouse. J Biol Chem (2008) 1.44
Minireview: G protein-coupled estrogen receptor-1, GPER-1: its mechanism of action and role in female reproductive cancer, renal and vascular physiology. Endocrinology (2012) 1.43
Minireview: Extranuclear steroid receptors: roles in modulation of cell functions. Mol Endocrinol (2010) 1.40
Stimulating the GPR30 estrogen receptor with a novel tamoxifen analogue activates SF-1 and promotes endometrial cell proliferation. Cancer Res (2009) 1.39
GPRC6A mediates the non-genomic effects of steroids. J Biol Chem (2010) 1.38
Estrogenic control of mitochondrial function and biogenesis. J Cell Biochem (2008) 1.37
Activation of GPR30 inhibits the growth of prostate cancer cells through sustained activation of Erk1/2, c-jun/c-fos-dependent upregulation of p21, and induction of G(2) cell-cycle arrest. Cell Death Differ (2010) 1.34
Estrogen signaling via a linear pathway involving insulin-like growth factor I receptor, matrix metalloproteinases, and epidermal growth factor receptor to activate mitogen-activated protein kinase in MCF-7 breast cancer cells. Endocrinology (2007) 1.32
Membrane-initiated estrogen signaling in hypothalamic neurons. Mol Cell Endocrinol (2008) 1.31
Novel actions of estrogen to promote proliferation: integration of cytoplasmic and nuclear pathways. Steroids (2008) 1.30
Membrane estrogen receptors stimulate intracellular calcium release and progesterone synthesis in hypothalamic astrocytes. J Neurosci (2010) 1.27
Membrane oestrogen receptor alpha signalling to cell functions. J Physiol (2009) 1.25
Mitochondrial effects of estrogen are mediated by estrogen receptor alpha in brain endothelial cells. J Pharmacol Exp Ther (2008) 1.24
Estrogen receptor-beta prevents cardiac fibrosis. Mol Endocrinol (2010) 1.24
Membrane estradiol signaling in the brain. Front Neuroendocrinol (2009) 1.22
Classical estrogen receptor alpha signaling mediates negative and positive feedback on gonadotropin-releasing hormone neuron firing. Endocrinology (2008) 1.22
G protein-coupled receptor 30: estrogen receptor or collaborator? Endocrinology (2009) 1.22
Non-genomic regulation of vascular cell function and growth by estrogen. Mol Cell Endocrinol (2009) 1.21
Estradiol-induced estrogen receptor-alpha trafficking. J Neurosci (2009) 1.21
Estrous cycle regulates activation of hippocampal Akt, LIM kinase, and neurotrophin receptors in C57BL/6 mice. Neuroscience (2008) 1.20
Estrogen Regulation of MicroRNA Expression. Curr Genomics (2009) 1.20
Rapid signaling by steroid receptors. Am J Physiol Regul Integr Comp Physiol (2008) 1.18
Estrogen signaling characteristics of Atlantic croaker G protein-coupled receptor 30 (GPR30) and evidence it is involved in maintenance of oocyte meiotic arrest. Endocrinology (2008) 1.18
Estrogen inhibits ATR signaling to cell cycle checkpoints and DNA repair. Mol Biol Cell (2009) 1.17
Estrogen inhibits RANKL-stimulated osteoclastic differentiation of human monocytes through estrogen and RANKL-regulated interaction of estrogen receptor-alpha with BCAR1 and Traf6. Exp Cell Res (2009) 1.15
Estrogen receptor beta functions through nongenomic mechanisms in lung cancer cells. Mol Endocrinol (2008) 1.14
The cell fate determination factor DACH1 is expressed in estrogen receptor-alpha-positive breast cancer and represses estrogen receptor-alpha signaling. Cancer Res (2009) 1.14
Non-nuclear estrogen receptor signaling in the endothelium. J Biol Chem (2011) 1.13
17beta-estradiol activates estrogen receptor beta-signalling and inhibits transient receptor potential vanilloid receptor 1 activation by capsaicin in adult rat nociceptor neurons. Endocrinology (2008) 1.08
An inherent role of microtubule network in the action of nuclear receptor. Proc Natl Acad Sci U S A (2006) 1.08
Rapid activation of ERK1/2 and AKT in human breast cancer cells by cadmium. Toxicol Appl Pharmacol (2007) 1.08
Cytoplasmic estrogen receptor in breast cancer. Clin Cancer Res (2011) 1.07
Signal integration through blending, bolstering and bifurcating of intracellular information. Nat Struct Mol Biol (2010) 1.07
Estrogen rapidly activates the PI3K/AKT pathway and hypoxia-inducible factor 1 and induces vascular endothelial growth factor A expression in luminal epithelial cells of the rat uterus. Biol Reprod (2009) 1.06
Heat shock protein 27 is required for sex steroid receptor trafficking to and functioning at the plasma membrane. Mol Cell Biol (2010) 1.05
Estrogen synthesis and signaling pathways during aging: from periphery to brain. Trends Mol Med (2013) 1.05
GPR30 co-localizes with cholinergic neurons in the basal forebrain and enhances potassium-stimulated acetylcholine release in the hippocampus. Psychoneuroendocrinology (2010) 1.04
DHHC-7 and -21 are palmitoylacyltransferases for sex steroid receptors. Mol Biol Cell (2011) 1.04
Estrogen induces rapid translocation of estrogen receptor beta, but not estrogen receptor alpha, to the neuronal plasma membrane. Neuroscience (2008) 1.03
Estrogenic compounds, estrogen receptors and vascular cell signaling in the aging blood vessels. Curr Med Chem (2009) 1.01
Membrane-localized estrogen receptor α is required for normal organ development and function. Dev Cell (2014) 1.01
Derailed estrogen signaling and breast cancer: an authentic couple. Endocr Rev (2012) 1.01
Tamoxifen regulates cell fate through mitochondrial estrogen receptor beta in breast cancer. Oncogene (2012) 1.01
Nervous system physiology regulated by membrane estrogen receptors. Rev Neurosci (2008) 1.01
Estrogenic regulation of the GnRH neuron. Front Endocrinol (Lausanne) (2012) 1.00
Transit of hormonal and EGF receptor-dependent signals through cholesterol-rich membranes. Steroids (2006) 1.00
Cross-talk between membrane-initiated and nuclear-initiated oestrogen signalling in the hypothalamus. J Neuroendocrinol (2009) 1.00
Estrogen Receptor {alpha} Enhances the Rate of Oxidative DNA Damage by Targeting an Equine Estrogen Catechol Metabolite to the Nucleus. J Biol Chem (2009) 0.99
Estradiol signaling in the regulation of reproduction and energy balance. Front Neuroendocrinol (2012) 0.99
Control of CNS neuronal excitability by estrogens via membrane-initiated signaling. Mol Cell Endocrinol (2009) 0.99
GPER mediates estrogen-induced signaling and proliferation in human breast epithelial cells and normal and malignant breast. Horm Cancer (2014) 0.99
Estrogen-like effects of cadmium in vivo do not appear to be mediated via the classical estrogen receptor transcriptional pathway. Environ Health Perspect (2010) 0.99
The Neurosteroid Progesterone Underlies Estrogen Positive Feedback of the LH Surge. Front Endocrinol (Lausanne) (2011) 0.97
17beta-estradiol-mediated neuroprotection and ERK activation require a pertussis toxin-sensitive mechanism involving GRK2 and beta-arrestin-1. J Neurosci (2009) 0.96
Nongenomic activation of phosphatidylinositol 3-kinase signaling by thyroid hormone receptors. Steroids (2008) 0.95
Neuroprotective actions of selective estrogen receptor modulators. Psychoneuroendocrinology (2009) 0.95
Viral vector-mediated overexpression of estrogen receptor-alpha in striatum enhances the estradiol-induced motor activity in female rats and estradiol-modulated GABA release. J Neurosci (2009) 0.94
The putative G-protein coupled estrogen receptor agonist G-1 suppresses proliferation of ovarian and breast cancer cells in a GPER-independent manner. Am J Transl Res (2012) 0.94
Membrane-initiated actions of estradiol that regulate reproduction, energy balance and body temperature. Front Neuroendocrinol (2012) 0.93
Extranuclear estrogen receptor's roles in physiology: lessons from mouse models. Am J Physiol Endocrinol Metab (2014) 0.93
N-3 poly-unsaturated fatty acids shift estrogen signaling to inhibit human breast cancer cell growth. PLoS One (2012) 0.93
Estrogen receptor signaling and its relationship to cytokines in systemic lupus erythematosus. J Biomed Biotechnol (2010) 0.92
Acute postischemic treatment with estrogen receptor-alpha agonist or estrogen receptor-beta agonist improves myocardial recovery. Surgery (2009) 0.92
2-methoxyestradiol binding of GPR30 down-regulates angiotensin AT(1) receptor. Eur J Pharmacol (2013) 0.92
Interactions between IGF-I, estrogen receptor-α (ERα), and ERβ in regulating growth/apoptosis of MCF-7 human breast cancer cells. J Endocrinol (2010) 0.90
Tamoxifen in early-stage estrogen receptor-positive breast cancer: overview of clinical use and molecular biomarkers for patient selection. Onco Targets Ther (2010) 0.90
The Effects of 17β-estradiol in Cancer are Mediated by Estrogen Receptor Signaling at the Plasma Membrane. Front Physiol (2011) 0.90
G protein-coupled estrogen receptor (GPER) expression in normal and abnormal endometrium. Reprod Sci (2012) 0.90
Hippocampal synthesis of sex steroids and corticosteroids: essential for modulation of synaptic plasticity. Front Endocrinol (Lausanne) (2011) 0.88
Autocrine regulation of cell proliferation by estrogen receptor-alpha in estrogen receptor-alpha-positive breast cancer cell lines. BMC Cancer (2009) 0.87
International Union of Basic and Clinical Pharmacology. XCVII. G Protein-Coupled Estrogen Receptor and Its Pharmacologic Modulators. Pharmacol Rev (2015) 0.87
Membrane-initiated estradiol actions mediate structural plasticity and reproduction. Front Neuroendocrinol (2012) 0.87
Estradiol and tamoxifen induce cell migration through GPR30 and activation of focal adhesion kinase (FAK) in endometrial cancers with low or without nuclear estrogen receptor α (ERα). PLoS One (2013) 0.85
Estrogen modulates metabolic pathway adaptation to available glucose in breast cancer cells. Mol Endocrinol (2012) 0.85
Cooperativity and complementarity: synergies in non-classical and classical glucocorticoid signaling. Cell Cycle (2012) 0.85
GPER mediates cardiotropic effects in spontaneously hypertensive rat hearts. PLoS One (2013) 0.84
The Paradox of Oestradiol-Induced Breast Cancer Cell Growth and Apoptosis. Curr Signal Transduct Ther (2009) 0.84
GPR30 differentially regulates short latency responses of luteinising hormone and prolactin secretion to oestradiol. J Neuroendocrinol (2009) 0.83
Localization and divergent profiles of estrogen receptors and aromatase in the vocal and auditory networks of a fish with alternative mating tactics. J Comp Neurol (2013) 0.83
G-protein Coupled Estrogen Receptor (GPER/GPR30) and Women's Health. J Menopausal Med (2015) 0.83
Stimulation of GPR30 increases release of EMMPRIN-containing microvesicles in human uterine epithelial cells. J Clin Endocrinol Metab (2012) 0.83
G protein-coupled receptors: extranuclear mediators for the non-genomic actions of steroids. Int J Mol Sci (2014) 0.82
Evolutionary origins of the estrogen signaling system: insights from amphioxus. J Steroid Biochem Mol Biol (2011) 0.82
Age-related differences in cardiac ischemia-reperfusion injury: effects of estrogen deficiency. Pflugers Arch (2013) 0.81
Extranuclear steroid receptors: nature and actions. Endocr Rev (2007) 2.72
A conserved mechanism for steroid receptor translocation to the plasma membrane. J Biol Chem (2007) 2.34
Proximal events in signaling by plasma membrane estrogen receptors. J Biol Chem (2002) 2.31
ERs associate with and regulate the production of caveolin: implications for signaling and cellular actions. Mol Endocrinol (2002) 2.20
Identification of a structural determinant necessary for the localization and function of estrogen receptor alpha at the plasma membrane. Mol Cell Biol (2003) 2.19
Plasma membrane estrogen receptors exist and functions as dimers. Mol Endocrinol (2004) 2.00
Functional estrogen receptors in the mitochondria of breast cancer cells. Mol Biol Cell (2006) 1.72
Integration of the non-genomic and genomic actions of estrogen. Membrane-initiated signaling by steroid to transcription and cell biology. J Biol Chem (2002) 1.60
Estrogen prevents cardiomyocyte apoptosis through inhibition of reactive oxygen species and differential regulation of p38 kinase isoforms. J Biol Chem (2005) 1.51
Developmental phenotype of a membrane only estrogen receptor alpha (MOER) mouse. J Biol Chem (2008) 1.44
BRCA1 inhibits membrane estrogen and growth factor receptor signaling to cell proliferation in breast cancer. Mol Cell Biol (2004) 1.43
Estrogen induces vascular wall dilation: mediation through kinase signaling to nitric oxide and estrogen receptors alpha and beta. J Biol Chem (2005) 1.41
Estrogen inhibits cardiomyocyte hypertrophy in vitro. Antagonism of calcineurin-related hypertrophy through induction of MCIP1. J Biol Chem (2005) 1.39
Estrogen inhibits cardiac hypertrophy: role of estrogen receptor-beta to inhibit calcineurin. Endocrinology (2008) 1.31
Estrogen receptor-beta prevents cardiac fibrosis. Mol Endocrinol (2010) 1.24
Requirements for estrogen receptor alpha membrane localization and function. Steroids (2005) 1.22
Minireview: Recent advances in extranuclear steroid receptor actions. Endocrinology (2011) 1.20
Estrogen inhibits ATR signaling to cell cycle checkpoints and DNA repair. Mol Biol Cell (2009) 1.17
Deciphering vascular endothelial cell growth factor/vascular permeability factor signaling to vascular permeability. Inhibition by atrial natriuretic peptide. J Biol Chem (2002) 1.17
Heat shock protein 27 is required for sex steroid receptor trafficking to and functioning at the plasma membrane. Mol Cell Biol (2010) 1.05
DHHC-7 and -21 are palmitoylacyltransferases for sex steroid receptors. Mol Biol Cell (2011) 1.04
Estrogen signaling in the cardiovascular system. Nucl Recept Signal (2006) 1.00
Estrogen reduces lipid content in the liver exclusively from membrane receptor signaling. Sci Signal (2013) 0.99
Estrogen regulates histone deacetylases to prevent cardiac hypertrophy. Mol Biol Cell (2013) 0.99
Src Inhibition with saracatinib reverses fulvestrant resistance in ER-positive ovarian cancer models in vitro and in vivo. Clin Cancer Res (2012) 0.91
Estrogen modulates the mechanical homeostasis of mouse arterial vessels through nitric oxide. Am J Physiol Heart Circ Physiol (2005) 0.89
Estrogen modulates metabolic pathway adaptation to available glucose in breast cancer cells. Mol Endocrinol (2012) 0.85
Estrogen receptors and cell signaling. Science (2005) 0.85
ERβ selective agonist inhibits angiotensin-induced cardiovascular pathology in female mice. Endocrinology (2013) 0.82
Acid-degradable core-shell nanoparticles for reversed tamoxifen-resistance in breast cancer by silencing manganese superoxide dismutase (MnSOD). Biomaterials (2013) 0.81
Estrogen receptor-beta and the cardiovascular system. Trends Endocrinol Metab (2002) 0.77