Published in Eur J Oral Sci on May 01, 2006
Enamel defects and ameloblast-specific expression in Enam knock-out/lacz knock-in mice. J Biol Chem (2008) 2.05
Partial rescue of the amelogenin null dental enamel phenotype. J Biol Chem (2008) 1.19
The amelogenin C-terminus is required for enamel development. J Dent Res (2009) 1.13
Dental enamel development: proteinases and their enamel matrix substrates. ISRN Dent (2013) 1.10
Leucine-rich amelogenin peptide induces osteogenesis in mouse embryonic stem cells. Biochem Biophys Res Commun (2007) 1.01
The leucine-rich amelogenin peptide alters the amelogenin null enamel phenotype. Cells Tissues Organs (2008) 0.97
Rescue of the murine amelogenin null phenotype with two amelogenin transgenes. Eur J Oral Sci (2011) 0.97
Regeneration of bone and periodontal ligament induced by recombinant amelogenin after periodontitis. J Cell Mol Med (2009) 0.96
Origin, splicing, and expression of rodent amelogenin exon 8. J Dent Res (2006) 0.94
Tracking endogenous amelogenin and ameloblastin in vivo. PLoS One (2014) 0.82
Matrix metalloproteinase-20 over-expression is detrimental to enamel development: a Mus musculus model. PLoS One (2014) 0.82
Expression and function of enamel-related gene products in calvarial development. J Dent Res (2013) 0.81
An amelogenin mutation leads to disruption of the odontogenic apparatus and aberrant expression of Notch1. J Oral Pathol Med (2010) 0.81
Amelogenins: Multi-Functional Enamel Matrix Proteins and Their Binding Partners. J Oral Biosci (2011) 0.80
Bodyweight assessment of enamelin null mice. Biomed Res Int (2012) 0.80
A critical function for TGF-beta signaling in the development of natural CD4+CD25+Foxp3+ regulatory T cells. Nat Immunol (2008) 4.28
Editing of CD1d-bound lipid antigens by endosomal lipid transfer proteins. Science (2003) 3.05
Dentin sialophosphoprotein knockout mouse teeth display widened predentin zone and develop defective dentin mineralization similar to human dentinogenesis imperfecta type III. J Biol Chem (2003) 3.03
Ameloblastin is a cell adhesion molecule required for maintaining the differentiation state of ameloblasts. J Cell Biol (2004) 3.00
The KIF3 motor transports N-cadherin and organizes the developing neuroepithelium. Nat Cell Biol (2005) 2.13
Control of the development of CD8αα+ intestinal intraepithelial lymphocytes by TGF-β. Nat Immunol (2011) 1.94
PI3K/mTOR inhibitor PF-04691502 antitumor activity is enhanced with induction of wild-type TP53 in human xenograft and murine knockout models of head and neck cancer. Clin Cancer Res (2013) 1.81
Cdk5 phosphorylation of doublecortin ser297 regulates its effect on neuronal migration. Neuron (2004) 1.70
Dentin sialoprotein and dentin phosphoprotein have distinct roles in dentin mineralization. Matrix Biol (2009) 1.64
Cyclin-dependent kinase 5 regulates E2F transcription factor through phosphorylation of Rb protein in neurons. Cell Cycle (2012) 1.62
Human and mouse enamel phenotypes resulting from mutation or altered expression of AMEL, ENAM, MMP20 and KLK4. Cells Tissues Organs (2008) 1.43
Cdk5 is required for multipolar-to-bipolar transition during radial neuronal migration and proper dendrite development of pyramidal neurons in the cerebral cortex. Development (2007) 1.40
Cyclin-dependent kinase-5 is involved in neuregulin-dependent activation of phosphatidylinositol 3-kinase and Akt activity mediating neuronal survival. J Biol Chem (2003) 1.38
Cyclin-dependent kinase 5 activity regulates pain signaling. Proc Natl Acad Sci U S A (2006) 1.34
Cyclin-dependent kinase 5 modulates nociceptive signaling through direct phosphorylation of transient receptor potential vanilloid 1. Proc Natl Acad Sci U S A (2006) 1.31
Phosphorylation of MEK1 by cdk5/p35 down-regulates the mitogen-activated protein kinase pathway. J Biol Chem (2001) 1.30
Chemopreventive and chemotherapeutic actions of mTOR inhibitor in genetically defined head and neck squamous cell carcinoma mouse model. Clin Cancer Res (2012) 1.30
Tumor necrosis factor-alpha regulates cyclin-dependent kinase 5 activity during pain signaling through transcriptional activation of p35. J Biol Chem (2008) 1.30
Progressive tumor formation in mice with conditional deletion of TGF-beta signaling in head and neck epithelia is associated with activation of the PI3K/Akt pathway. Cancer Res (2009) 1.24
Increased activity of cyclin-dependent kinase 5 leads to attenuation of cocaine-mediated dopamine signaling. Proc Natl Acad Sci U S A (2005) 1.21
Control of cyclin-dependent kinase 5 (Cdk5) activity by glutamatergic regulation of p35 stability. J Neurochem (2005) 1.20
MicroRNA-135b acts as a tumor promoter by targeting the hypoxia-inducible factor pathway in genetically defined mouse model of head and neck squamous cell carcinoma. Cancer Lett (2013) 1.19
DSPP effects on in vivo bone mineralization. Bone (2008) 1.19
Partial rescue of the amelogenin null dental enamel phenotype. J Biol Chem (2008) 1.19
Dph3, a small protein required for diphthamide biosynthesis, is essential in mouse development. Mol Cell Biol (2006) 1.16
Spatial expression of Cbfa1/Runx2 isoforms in teeth and characterization of binding sites in the DSPP gene. Connect Tissue Res (2002) 1.15
Transgenic mouse expressing human mutant alpha-galactosidase A in an endogenous enzyme deficient background: a biochemical animal model for studying active-site specific chaperone therapy for Fabry disease. Biochim Biophys Acta (2004) 1.14
Genetically altered mouse models: the good, the bad, and the ugly. Crit Rev Oral Biol Med (2003) 1.14
Leucine-rich amelogenin peptide: a candidate signaling molecule during cementogenesis. J Periodontol (2004) 1.13
Cyclin-dependent kinase 5 prevents neuronal apoptosis by negative regulation of c-Jun N-terminal kinase 3. EMBO J (2002) 1.13
Cdk5: a new player in pain signaling. Cell Cycle (2006) 1.10
Critical roles of the TGF-beta type I receptor ALK5 in perichondrial formation and function, cartilage integrity, and osteoblast differentiation during growth plate development. Dev Biol (2009) 1.09
Cyclin-dependent kinase 5 is a regulator of podocyte differentiation, proliferation, and morphology. Am J Pathol (2004) 1.08
Conditional overexpression of TGF-beta1 disrupts mouse salivary gland development and function. Lab Invest (2010) 1.08
Tau phosphorylation by cyclin-dependent kinase 5/p39 during brain development reduces its affinity for microtubules. J Biol Chem (2003) 1.07
A novel role of periostin in postnatal tooth formation and mineralization. J Biol Chem (2010) 1.03
A developmental comparison of matrix metalloproteinase-20 and amelogenin null mouse enamel. Eur J Oral Sci (2006) 1.03
Physiological implications of DLX homeoproteins in enamel formation. J Cell Physiol (2008) 1.01
Effects of sodium fluoride on the actin cytoskeleton of murine ameloblasts. Arch Oral Biol (2005) 1.01
Cyclin-dependent kinase 5 is required for control of neuroblast migration in the postnatal subventricular zone. J Neurosci (2007) 1.01
Amelogenin: a potential regulator of cementum-associated genes. J Periodontol (2003) 1.00
Perinatal abrogation of Cdk5 expression in brain results in neuronal migration defects. Proc Natl Acad Sci U S A (2004) 1.00
TGF-beta receptor I conditional knockout mice develop spontaneous squamous cell carcinoma. Cell Cycle (2007) 0.99
Cyclin-dependent kinase 5 activity is required for T cell activation and induction of experimental autoimmune encephalomyelitis. J Exp Med (2010) 0.99
Overview: engineering transgenic constructs and mice. Curr Protoc Cell Biol (2009) 0.98
The leucine-rich amelogenin peptide alters the amelogenin null enamel phenotype. Cells Tissues Organs (2008) 0.97
Rescue of the murine amelogenin null phenotype with two amelogenin transgenes. Eur J Oral Sci (2011) 0.97
Regeneration of bone and periodontal ligament induced by recombinant amelogenin after periodontitis. J Cell Mol Med (2009) 0.96
Dentin sialophosphoprotein and dentin matrix protein-1: Two highly phosphorylated proteins in mineralized tissues. Arch Oral Biol (2012) 0.96
The receptor activator of nuclear factor-kappa B ligand-mediated osteoclastogenic pathway is elevated in amelogenin-null mice. J Biol Chem (2003) 0.95
Conditional deletion of neuronal cyclin-dependent kinase 5 in developing forebrain results in microglial activation and neurodegeneration. Am J Pathol (2009) 0.95
Genetic evidence for key roles of decorin and biglycan in dentin mineralization. Matrix Biol (2009) 0.94
Overexpression of transforming growth factor-beta1 in teeth results in detachment of ameloblasts and enamel defects. Eur J Oral Sci (2006) 0.93
Neurofilament tail phosphorylation: identity of the RT-97 phosphoepitope and regulation in neurons by cross-talk among proline-directed kinases. J Neurochem (2008) 0.93
Extracellular heat shock protein HSP90beta secreted by MG63 osteosarcoma cells inhibits activation of latent TGF-beta1. Biochem Biophys Res Commun (2010) 0.92
Amelogenins regulate expression of genes associated with cementoblasts in vitro. Eur J Oral Sci (2006) 0.92
Resveratrol inhibits Cdk5 activity through regulation of p35 expression. Mol Pain (2011) 0.92
Transforming growth factor-β1 regulates Cdk5 activity in primary sensory neurons. J Biol Chem (2012) 0.91
Induction of autophagy-dependent cell death by the survivin suppressant YM155 in salivary adenoid cystic carcinoma. Apoptosis (2014) 0.91
Molecular Roles of Cdk5 in Pain Signaling. Drug Discov Today Ther Strateg (2009) 0.90
Female mice are more susceptible to developing inflammatory disorders due to impaired transforming growth factor beta signaling in salivary glands. Arthritis Rheum (2007) 0.90
Amelogenesis imperfecta due to a mutation of the enamelin gene: clinical case with genotype-phenotype correlations. Pediatr Dent (2010) 0.90
Endocrine expression of the active form of TGF-beta1 in the TGF-beta1 null mice fails to ameliorate lethal phenotype. Cytokine (2002) 0.89
Inhibition of cyclin-dependent kinase 5 but not of glycogen synthase kinase 3-β prevents neurite retraction and tau hyperphosphorylation caused by secretable products of human T-cell leukemia virus type I-infected lymphocytes. J Neurosci Res (2011) 0.88
Cyclin-dependent kinase 5/p35 contributes synergistically with Reelin/Dab1 to the positioning of facial branchiomotor and inferior olive neurons in the developing mouse hindbrain. J Neurosci (2002) 0.88
Generation of gene knockout mice by ES cell microinjection. Curr Protoc Cell Biol (2009) 0.88
Generation of transgenic mice. Curr Protoc Cell Biol (2009) 0.88
Dental enamel structure is altered by expression of dominant negative RhoA in ameloblasts. Cells Tissues Organs (2011) 0.87
Phosphorylation of p27Kip1 at Thr187 by cyclin-dependent kinase 5 modulates neural stem cell differentiation. Mol Biol Cell (2010) 0.87
Increased globotriaosylceramide levels in a transgenic mouse expressing human alpha1,4-galactosyltransferase and a mouse model for treating Fabry disease. J Biochem (2010) 0.86
Manipulation of mouse embryonic stem cells for knockout mouse production. Curr Protoc Cell Biol (2009) 0.86
A large X-chromosomal deletion is associated with microphthalmia with linear skin defects (MLS) and amelogenesis imperfecta (XAI). Am J Med Genet A (2009) 0.86
Overview: generation of gene knockout mice. Curr Protoc Cell Biol (2009) 0.86
The use of animal models to explore amelogenin variants in amelogenesis imperfecta. Cells Tissues Organs (2005) 0.85
Neuron-specific TGF-beta signaling deficiency results in retinal detachment and cataracts in mice. Biochem Biophys Res Commun (2006) 0.85
Full length amelogenin binds to cell surface LAMP-1 on tooth root/periodontium associated cells. Arch Oral Biol (2010) 0.85
TGF-ß regulates enamel mineralization and maturation through KLK4 expression. PLoS One (2013) 0.84
A symptomatic Fabry disease mouse model generated by inducing globotriaosylceramide synthesis. Biochem J (2013) 0.84
Leucine rich amelogenin peptide alters ameloblast differentiation in vivo. Matrix Biol (2013) 0.84
Targeting of interleukin-13 receptor α2 for treatment of head and neck squamous cell carcinoma induced by conditional deletion of TGF-β and PTEN signaling. J Transl Med (2013) 0.84
Conditional deletion of cyclin-dependent kinase 5 in primary sensory neurons leads to atypical skin lesions. Cell Cycle (2008) 0.83
TGF-β1 sensitizes TRPV1 through Cdk5 signaling in odontoblast-like cells. Mol Pain (2013) 0.83
Inhibition of mTOR reduces anal carcinogenesis in transgenic mouse model. PLoS One (2013) 0.82
Cdk5 regulates Rap1 activity. Neurochem Int (2013) 0.81
Hypomyelination phenotype caused by impaired differentiation of oligodendrocytes in Emx1-cre mediated Cdk5 conditional knockout mice. Neurochem Res (2011) 0.81
A method for rapid demineralization of teeth and bones. Open Dent J (2010) 0.81
Transforming growth factor-β3 (TGF-β3) knock-in ameliorates inflammation due to TGF-β1 deficiency while promoting glucose tolerance. J Biol Chem (2013) 0.81
An amelogenin mutation leads to disruption of the odontogenic apparatus and aberrant expression of Notch1. J Oral Pathol Med (2010) 0.81
Neuronal nuclear organization is controlled by cyclin-dependent kinase 5 phosphorylation of Ras Guanine nucleotide releasing factor-1. Neurosignals (2006) 0.80
Amelogenins: Multi-Functional Enamel Matrix Proteins and Their Binding Partners. J Oral Biosci (2011) 0.80