Published in Mol Cell on May 05, 2006
A dynamic model for replication protein A (RPA) function in DNA processing pathways. Nucleic Acids Res (2006) 4.49
Acetylation of histone H3 lysine 56 regulates replication-coupled nucleosome assembly. Cell (2008) 3.96
Chaperoning histones during DNA replication and repair. Cell (2010) 2.99
Chromatin replication and epigenome maintenance. Nat Rev Mol Cell Biol (2012) 2.25
FACT and Asf1 regulate nucleosome dynamics and coactivator binding at the HO promoter. Mol Cell (2009) 2.19
The histone shuffle: histone chaperones in an energetic dance. Trends Biochem Sci (2010) 1.89
An E3 ubiquitin ligase prevents ectopic localization of the centromeric histone H3 variant via the centromere targeting domain. Mol Cell (2010) 1.78
Pleckstrin homology (PH) domains and phosphoinositides. Biochem Soc Symp (2007) 1.74
Histone chaperones in nucleosome assembly and human disease. Nat Struct Mol Biol (2013) 1.74
Histone chaperone FACT coordinates nucleosome interaction through multiple synergistic binding events. J Biol Chem (2011) 1.63
Chromatin and transcription in yeast. Genetics (2012) 1.61
The FACT Spt16 "peptidase" domain is a histone H3-H4 binding module. Proc Natl Acad Sci U S A (2008) 1.50
Structural basis of histone H2A-H2B recognition by the essential chaperone FACT. Nature (2013) 1.47
Opposing roles for Set2 and yFACT in regulating TBP binding at promoters. EMBO J (2006) 1.36
The histone chaperone FACT: structural insights and mechanisms for nucleosome reorganization. J Biol Chem (2011) 1.34
Histone3 lysine4 trimethylation regulated by the facilitates chromatin transcription complex is critical for DNA cleavage in class switch recombination. Proc Natl Acad Sci U S A (2010) 1.30
The role of FACT in making and breaking nucleosomes. Biochim Biophys Acta (2011) 1.25
Chromatin and DNA replication. Cold Spring Harb Perspect Biol (2013) 1.22
Structural basis for recognition of H3K56-acetylated histone H3-H4 by the chaperone Rtt106. Nature (2012) 1.21
Nucleolin associates with the human cytomegalovirus DNA polymerase accessory subunit UL44 and is necessary for efficient viral replication. J Virol (2009) 1.19
Insight into the mechanism of nucleosome reorganization from histone mutants that suppress defects in the FACT histone chaperone. Genetics (2011) 1.11
RPA-coated single-stranded DNA as a platform for post-translational modifications in the DNA damage response. Cell Res (2014) 1.10
A role for Chd1 and Set2 in negatively regulating DNA replication in Saccharomyces cerevisiae. Genetics (2008) 1.09
Towards a mechanism for histone chaperones. Biochim Biophys Acta (2014) 1.06
FACT prevents the accumulation of free histones evicted from transcribed chromatin and a subsequent cell cycle delay in G1. PLoS Genet (2010) 1.05
Structural analysis of Rtt106p reveals a DNA binding role required for heterochromatin silencing. J Biol Chem (2009) 1.04
A gene-specific requirement for FACT during transcription is related to the chromatin organization of the transcribed region. Mol Cell Biol (2006) 1.04
Evidence that the localization of the elongation factor Spt16 across transcribed genes is dependent upon histone H3 integrity in Saccharomyces cerevisiae. Genetics (2007) 1.04
Different genetic functions for the Rpd3(L) and Rpd3(S) complexes suggest competition between NuA4 and Rpd3(S). Mol Cell Biol (2008) 1.03
Phosphorylated intrinsically disordered region of FACT masks its nucleosomal DNA binding elements. J Biol Chem (2009) 1.01
FACT Disrupts Nucleosome Structure by Binding H2A-H2B with Conserved Peptide Motifs. Mol Cell (2015) 1.00
The histone chaperone facilitates chromatin transcription (FACT) protein maintains normal replication fork rates. J Biol Chem (2011) 0.99
The yeast and human FACT chromatin-reorganizing complexes solve R-loop-mediated transcription-replication conflicts. Genes Dev (2014) 0.99
Ubiquitylation of FACT by the cullin-E3 ligase Rtt101 connects FACT to DNA replication. Genes Dev (2010) 0.98
The FACT subunit TbSpt16 is involved in cell cycle specific control of VSG expression sites in Trypanosoma brucei. Mol Microbiol (2010) 0.98
Structure of the Spt16 middle domain reveals functional features of the histone chaperone FACT. J Biol Chem (2013) 0.98
Histone chaperones, histone acetylation, and the fluidity of the chromogenome. J Cell Physiol (2010) 0.97
GCN5 is a positive regulator of origins of DNA replication in Saccharomyces cerevisiae. PLoS One (2010) 0.94
Two surfaces on the histone chaperone Rtt106 mediate histone binding, replication, and silencing. Proc Natl Acad Sci U S A (2011) 0.92
A PH domain in the Arf GTPase-activating protein (GAP) ARAP1 binds phosphatidylinositol 3,4,5-trisphosphate and regulates Arf GAP activity independently of recruitment to the plasma membranes. J Biol Chem (2009) 0.92
The FACT complex interacts with the E3 ubiquitin ligase Psh1 to prevent ectopic localization of CENP-A. Genes Dev (2014) 0.91
Mutant versions of the S. cerevisiae transcription elongation factor Spt16 define regions of Spt16 that functionally interact with histone H3. PLoS One (2011) 0.90
Histone Chaperones Spt6 and FACT: Similarities and Differences in Modes of Action at Transcribed Genes. Genet Res Int (2011) 0.90
Nucleosome assembly and epigenetic inheritance. Protein Cell (2010) 0.89
Identification of Mutant Versions of the Spt16 Histone Chaperone That Are Defective for Transcription-Coupled Nucleosome Occupancy in Saccharomyces cerevisiae. G3 (Bethesda) (2012) 0.86
Histones, histone chaperones and nucleosome assembly. Protein Cell (2010) 0.85
Catch me if you can: how the histone chaperone FACT capitalizes on nucleosome breathing. Nucleus (2013) 0.84
Integrated molecular mechanism directing nucleosome reorganization by human FACT. Genes Dev (2016) 0.83
Biphasic chromatin binding of histone chaperone FACT during eukaryotic chromatin DNA replication. Biochim Biophys Acta (2011) 0.81
Complementation of Yeast Genes with Human Genes as an Experimental Platform for Functional Testing of Human Genetic Variants. Genetics (2015) 0.81
Using HHsearch to tackle proteins of unknown function: A pilot study with PH domains. Traffic (2016) 0.79
FACT Proteins, SUPT16H and SSRP1, Are Transcriptional Suppressors of HIV-1 and HTLV-1 That Facilitate Viral Latency. J Biol Chem (2015) 0.79
Emerging players in the initiation of eukaryotic DNA replication. Cell Div (2012) 0.78
Sites of acetylation on newly synthesized histone H4 are required for chromatin assembly and DNA damage response signaling. Mol Cell Biol (2013) 0.78
Genetic interactions between POB3 and the acetylation of newly synthesized histones. Curr Genet (2011) 0.78
The FACT histone chaperone guides histone H4 into its nucleosomal conformation in Saccharomyces cerevisiae. Genetics (2013) 0.78
Histone chaperone networks shaping chromatin function. Nat Rev Mol Cell Biol (2017) 0.78
Crystal Structure of Human SSRP1 Middle Domain Reveals a Role in DNA Binding. Sci Rep (2015) 0.77
FACT, the Bur kinase pathway, and the histone co-repressor HirC have overlapping nucleosome-related roles in yeast transcription elongation. PLoS One (2011) 0.77
Histone chaperone-mediated nucleosome assembly process. PLoS One (2015) 0.76
Structure of the human histone chaperone FACT Spt16 N-terminal domain. Acta Crystallogr F Struct Biol Commun (2016) 0.75
Sperm and spermatids contain different proteins and bind distinct egg factors. Int J Mol Sci (2014) 0.75
Fine-Tuning of FACT by the Ubiquitin Proteasome System in Regulation of Transcriptional Elongation. Mol Cell Biol (2016) 0.75
Regulation of Replication Fork Advance and Stability by Nucleosome Assembly. Genes (Basel) (2017) 0.75
The Abundant Histone Chaperones Spt6 and FACT Collaborate to Assemble, Inspect, and Maintain Chromatin Structure in Saccharomyces cerevisiae. Genetics (2015) 0.75
Ubiquitin-binding domains. Nat Rev Mol Cell Biol (2005) 6.77
X-ray structures of the hexameric building block of the HIV capsid. Cell (2009) 4.08
The ubiquitin binding domain ZnF UBP recognizes the C-terminal diglycine motif of unanchored ubiquitin. Cell (2006) 3.46
Structural and biochemical studies of ALIX/AIP1 and its role in retrovirus budding. Cell (2007) 3.06
Inositol hexakisphosphate is bound in the ADAR2 core and required for RNA editing. Science (2005) 2.94
Mobilizing the proteolytic machine: cell biological roles of proteasome activators and inhibitors. Trends Cell Biol (2005) 2.73
The 1.9 A structure of a proteasome-11S activator complex and implications for proteasome-PAN/PA700 interactions. Mol Cell (2005) 2.68
Structural and mechanistic studies of VPS4 proteins. EMBO J (2005) 2.58
UNC119 is required for G protein trafficking in sensory neurons. Nat Neurosci (2011) 2.38
Structure and ubiquitin binding of the ubiquitin-interacting motif. J Biol Chem (2003) 2.19
Ubiquitin recognition by the human TSG101 protein. Mol Cell (2004) 2.17
Human ESCRT-II complex and its role in human immunodeficiency virus type 1 release. J Virol (2006) 2.06
Structural basis for ESCRT-III protein autoinhibition. Nat Struct Mol Biol (2009) 1.98
ALIX-CHMP4 interactions in the human ESCRT pathway. Proc Natl Acad Sci U S A (2008) 1.91
Autoregulation of the rsc4 tandem bromodomain by gcn5 acetylation. Mol Cell (2007) 1.85
yFACT induces global accessibility of nucleosomal DNA without H2A-H2B displacement. Mol Cell (2009) 1.85
Crystal structure of the middle and C-terminal domains of the flagellar rotor protein FliG. EMBO J (2002) 1.79
Structure of the antiviral assembly inhibitor CAP-1 complex with the HIV-1 CA protein. J Mol Biol (2007) 1.78
Structural insights into the catalytic mechanism of cyclophilin A. Nat Struct Biol (2003) 1.78
Potent D-peptide inhibitors of HIV-1 entry. Proc Natl Acad Sci U S A (2007) 1.76
Structural and functional studies of ALIX interactions with YPX(n)L late domains of HIV-1 and EIAV. Nat Struct Mol Biol (2007) 1.76
Crystal structure of the flagellar rotor protein FliN from Thermotoga maritima. J Bacteriol (2005) 1.65
Proteasome activators. Mol Cell (2011) 1.62
Crystal structure of the beta-finger domain of Prp8 reveals analogy to ribosomal proteins. Proc Natl Acad Sci U S A (2008) 1.56
The pore of activated 20S proteasomes has an ordered 7-fold symmetric conformation. EMBO J (2003) 1.50
Structural biology of the proteasome. Annu Rev Biophys (2013) 1.42
Implications for viral capsid assembly from crystal structures of HIV-1 Gag(1-278) and CA(N)(133-278). Biochemistry (2006) 1.41
Structural basis for ubiquitin recognition by the human ESCRT-II EAP45 GLUE domain. Nat Struct Mol Biol (2006) 1.41
CD94-NKG2A recognition of human leukocyte antigen (HLA)-E bound to an HLA class I leader sequence. J Exp Med (2008) 1.40
Structural and functional analysis of the Spt16p N-terminal domain reveals overlapping roles of yFACT subunits. J Biol Chem (2007) 1.38
An asymmetric interface between the regulatory and core particles of the proteasome. Nat Struct Mol Biol (2011) 1.36
Structure of a Blm10 complex reveals common mechanisms for proteasome binding and gate opening. Mol Cell (2010) 1.36
Opposing roles for Set2 and yFACT in regulating TBP binding at promoters. EMBO J (2006) 1.36
Multiple Nhp6 molecules are required to recruit Spt16-Pob3 to form yFACT complexes and to reorganize nucleosomes. J Biol Chem (2003) 1.35
A highly tilted binding mode by a self-reactive T cell receptor results in altered engagement of peptide and MHC. J Exp Med (2011) 1.34
The yeast FACT complex has a role in transcriptional initiation. Mol Cell Biol (2005) 1.33
Design of a potent D-peptide HIV-1 entry inhibitor with a strong barrier to resistance. J Virol (2010) 1.33
Cryo-EM structure of dodecameric Vps4p and its 2:1 complex with Vta1p. J Mol Biol (2008) 1.33
Structural features of nucleosomes reorganized by yeast FACT and its HMG box component, Nhp6. Mol Cell Biol (2004) 1.32
Structural basis for tetrapyrrole coordination by uroporphyrinogen decarboxylase. EMBO J (2003) 1.31
Water networks contribute to enthalpy/entropy compensation in protein-ligand binding. J Am Chem Soc (2013) 1.31
Structural and functional studies on the extracellular domain of BST2/tetherin in reduced and oxidized conformations. Proc Natl Acad Sci U S A (2010) 1.29
The role of FACT in making and breaking nucleosomes. Biochim Biophys Acta (2011) 1.25
Crystal structure of the C-terminal domain of splicing factor Prp8 carrying retinitis pigmentosa mutants. Protein Sci (2007) 1.25
Structure of the Blm10-20 S proteasome complex by cryo-electron microscopy. Insights into the mechanism of activation of mature yeast proteasomes. J Mol Biol (2006) 1.22
Molecular basis of phosphatidylinositol 4-phosphate and ARF1 GTPase recognition by the FAPP1 pleckstrin homology (PH) domain. J Biol Chem (2011) 1.21
Structural models for interactions between the 20S proteasome and its PAN/19S activators. J Biol Chem (2009) 1.17
Crystal structure of a biliverdin IXalpha reductase enzyme-cofactor complex. J Mol Biol (2002) 1.17
Structures along the catalytic pathway of PrmC/HemK, an N5-glutamine AdoMet-dependent methyltransferase. Biochemistry (2003) 1.17
Design and characterization of ebolavirus GP prehairpin intermediate mimics as drug targets. Protein Sci (2014) 1.16
Crystal structure and RNA binding of the Tex protein from Pseudomonas aeruginosa. J Mol Biol (2008) 1.15
Biochemical and structural studies of yeast Vps4 oligomerization. J Mol Biol (2008) 1.15
Insight into the mechanism of nucleosome reorganization from histone mutants that suppress defects in the FACT histone chaperone. Genetics (2011) 1.11
Molecular architecture of a dynamin adaptor: implications for assembly of mitochondrial fission complexes. J Cell Biol (2010) 1.10
The structure of Saccharomyces cerevisiae Met8p, a bifunctional dehydrogenase and ferrochelatase. EMBO J (2002) 1.09
A role for Chd1 and Set2 in negatively regulating DNA replication in Saccharomyces cerevisiae. Genetics (2008) 1.09
Differential quantum tunneling contributions in nitroalkane oxidase catalyzed and the uncatalyzed proton transfer reaction. Proc Natl Acad Sci U S A (2009) 1.08
Identification and structural characterization of the ALIX-binding late domains of simian immunodeficiency virus SIVmac239 and SIVagmTan-1. J Virol (2010) 1.06
Structural and biochemical characterization of Gun4 suggests a mechanism for its role in chlorophyll biosynthesis. Biochemistry (2005) 1.04
Structure of the membrane-tethering GRASP domain reveals a unique PDZ ligand interaction that mediates Golgi biogenesis. J Biol Chem (2011) 1.04
Structure of ATP-bound human ATP:cobalamin adenosyltransferase. Biochemistry (2006) 1.04
Proteasome degradation: enter the substrate. Trends Cell Biol (2003) 1.02
Structural basis of ubiquitylation. Curr Opin Struct Biol (2002) 1.02
How to assemble a capsid. Cell (2007) 1.00
X-ray structures of isopentenyl phosphate kinase. ACS Chem Biol (2010) 1.00
The effect of clade-specific sequence polymorphisms on HIV-1 protease activity and inhibitor resistance pathways. J Virol (2010) 0.99
Emergent Properties of EWS/FLI Regulation via GGAA Microsatellites in Ewing's Sarcoma. Genes Cancer (2010) 0.98
Ubiquitylation of FACT by the cullin-E3 ligase Rtt101 connects FACT to DNA replication. Genes Dev (2010) 0.98
Structure of the Spt16 middle domain reveals functional features of the histone chaperone FACT. J Biol Chem (2013) 0.98
Activation of the retroviral budding factor ALIX. J Virol (2011) 0.97
Crystal structure of the oxygen-dependant coproporphyrinogen oxidase (Hem13p) of Saccharomyces cerevisiae. J Biol Chem (2004) 0.96
Selective Oma1 protease-mediated proteolysis of Cox1 subunit of cytochrome oxidase in assembly mutants. J Biol Chem (2012) 0.94
Structure of an actin-related subcomplex of the SWI/SNF chromatin remodeler. Proc Natl Acad Sci U S A (2013) 0.93
Crystal structures of the S. cerevisiae Spt6 core and C-terminal tandem SH2 domain. J Mol Biol (2011) 0.91
Structure of Shroom domain 2 reveals a three-segmented coiled-coil required for dimerization, Rock binding, and apical constriction. Mol Biol Cell (2012) 0.91
Structure of the class IV adenylyl cyclase reveals a novel fold. J Mol Biol (2006) 0.90
Cdc73 subunit of Paf1 complex contains C-terminal Ras-like domain that promotes association of Paf1 complex with chromatin. J Biol Chem (2012) 0.90
Structural reorganization triggered by charging of Lys residues in the hydrophobic interior of a protein. Structure (2012) 0.89
Structure and biological importance of the Spn1-Spt6 interaction, and its regulatory role in nucleosome binding. Mol Cell (2010) 0.89
Structure of a proteasome Pba1-Pba2 complex: implications for proteasome assembly, activation, and biological function. J Biol Chem (2012) 0.87
Two structures of a lambda Cro variant highlight dimer flexibility but disfavor major dimer distortions upon specific binding of cognate DNA. J Mol Biol (2007) 0.86
Two novel uroporphyrinogen decarboxylase (URO-D) mutations causing hepatoerythropoietic porphyria (HEP). Transl Res (2007) 0.86
Structure and mechanistic implications of a uroporphyrinogen III synthase-product complex. Biochemistry (2008) 0.85
Structure and function of SirC from Bacillus megaterium: a metal-binding precorrin-2 dehydrogenase. Biochem J (2008) 0.84
Substrate shuttling between active sites of uroporphyrinogen decarboxylase is not required to generate coproporphyrinogen. J Mol Biol (2009) 0.83