Published in J Biol Chem on October 03, 2011
Chromatin replication and epigenome maintenance. Nat Rev Mol Cell Biol (2012) 2.25
Histone chaperones in nucleosome assembly and human disease. Nat Struct Mol Biol (2013) 1.74
Structural basis of histone H2A-H2B recognition by the essential chaperone FACT. Nature (2013) 1.47
Histone turnover and chromatin accessibility: Critical mediators of neurological development, plasticity, and disease. Bioessays (2016) 1.40
Histone chaperone FACT action during transcription through chromatin by RNA polymerase II. Proc Natl Acad Sci U S A (2013) 1.32
Glutamine methylation in histone H2A is an RNA-polymerase-I-dedicated modification. Nature (2013) 1.27
Mechanism of transcription through a nucleosome by RNA polymerase II. Biochim Biophys Acta (2012) 1.19
Yeast CAF-1 assembles histone (H3-H4)2 tetramers prior to DNA deposition. Nucleic Acids Res (2012) 1.18
Evidence for monomeric actin function in INO80 chromatin remodeling. Nat Struct Mol Biol (2013) 1.12
Molecular functions of the TLE tetramerization domain in Wnt target gene repression. EMBO J (2014) 1.02
FACT Disrupts Nucleosome Structure by Binding H2A-H2B with Conserved Peptide Motifs. Mol Cell (2015) 1.00
Structure of the Spt16 middle domain reveals functional features of the histone chaperone FACT. J Biol Chem (2013) 0.98
Automodification switches PARP-1 function from chromatin architectural protein to histone chaperone. Proc Natl Acad Sci U S A (2014) 0.94
Linker histone H1.0 interacts with an extensive network of proteins found in the nucleolus. Nucleic Acids Res (2013) 0.92
The FACT complex interacts with the E3 ubiquitin ligase Psh1 to prevent ectopic localization of CENP-A. Genes Dev (2014) 0.91
Making sense of transcribing chromatin. Curr Opin Cell Biol (2012) 0.89
MYC cofactors: molecular switches controlling diverse biological outcomes. Cold Spring Harb Perspect Med (2014) 0.88
Dissecting the roles of the histone chaperones reveals the evolutionary conserved mechanism of transcription-coupled deposition of H3.3. Nucleic Acids Res (2013) 0.87
Complex mutual regulation of facilitates chromatin transcription (FACT) subunits on both mRNA and protein levels in human cells. Cell Cycle (2013) 0.87
A highly conserved region within H2B is important for FACT to act on nucleosomes. Mol Cell Biol (2013) 0.87
Identification of Mutant Versions of the Spt16 Histone Chaperone That Are Defective for Transcription-Coupled Nucleosome Occupancy in Saccharomyces cerevisiae. G3 (Bethesda) (2012) 0.86
The intrinsically disordered distal face of nucleoplasmin recognizes distinct oligomerization states of histones. Nucleic Acids Res (2013) 0.85
Linker histone H1 and protein-protein interactions. Biochim Biophys Acta (2015) 0.85
Catch me if you can: how the histone chaperone FACT capitalizes on nucleosome breathing. Nucleus (2013) 0.84
Myogenin recruits the histone chaperone facilitates chromatin transcription (FACT) to promote nucleosome disassembly at muscle-specific genes. J Biol Chem (2013) 0.83
Integrated molecular mechanism directing nucleosome reorganization by human FACT. Genes Dev (2016) 0.83
De Novo proteome analysis of genetically modified tumor cells by a metabolic labeling/azide-alkyne cycloaddition approach. Mol Cell Proteomics (2014) 0.82
Scm3 deposits a (Cse4-H4)2 tetramer onto DNA through a Cse4-H4 dimer intermediate. Nucleic Acids Res (2014) 0.80
A quantitative investigation of linker histone interactions with nucleosomes and chromatin. Sci Rep (2016) 0.80
FACT in Cell Differentiation and Carcinogenesis. Oncotarget (2011) 0.79
A nucleosomal region important for ensuring proper interactions between the transcription elongation factor Spt16 and transcribed genes in Saccharomyces cerevisiae. G3 (Bethesda) (2013) 0.79
Large-scale ATP-independent nucleosome unfolding by a histone chaperone. Nat Struct Mol Biol (2016) 0.79
Phosphorylation-coupled intramolecular dynamics of unstructured regions in chromatin remodeler FACT. Biophys J (2013) 0.78
UpSETing chromatin during non-coding RNA production. Epigenetics Chromatin (2013) 0.78
The FACT histone chaperone guides histone H4 into its nucleosomal conformation in Saccharomyces cerevisiae. Genetics (2013) 0.78
Crystal Structure of Human SSRP1 Middle Domain Reveals a Role in DNA Binding. Sci Rep (2015) 0.77
Experimental analysis of hFACT action during Pol II transcription in vitro. Methods Mol Biol (2015) 0.77
FACT is a sensor of DNA torsional stress in eukaryotic cells. Nucleic Acids Res (2017) 0.77
FACT plays a major role in histone dynamics affecting VSG expression site control in Trypanosoma brucei. Mol Microbiol (2014) 0.76
FACT and the H2B N tail. Mol Cell Biol (2013) 0.75
Paf1 Has Distinct Roles in Transcription Elongation and Differential Transcript Fate. Mol Cell (2017) 0.75
Stabilization of Nucleosomes by Histone Tails and by FACT Revealed by spFRET Microscopy. Cancers (Basel) (2017) 0.75
The FACT Complex Promotes Avian Leukosis Virus DNA Integration. J Virol (2017) 0.75
The CENP-T/-W complex is a binding partner of the histone chaperone FACT. Genes Dev (2016) 0.75
A Quantitative Characterization of Nucleoplasmin/Histone Complexes Reveals Chaperone Versatility. Sci Rep (2016) 0.75
The Abundant Histone Chaperones Spt6 and FACT Collaborate to Assemble, Inspect, and Maintain Chromatin Structure in Saccharomyces cerevisiae. Genetics (2015) 0.75
A systematic mutational analysis of a histone H3 residue in budding yeast provides insights into chromatin dynamics. G3 (Bethesda) (2015) 0.75
Structure of the human histone chaperone FACT Spt16 N-terminal domain. Acta Crystallogr F Struct Biol Commun (2016) 0.75
The Modifier of Transcription 1 (Mot1) ATPase and Spt16 Histone Chaperone Co-regulate Transcription through Preinitiation Complex Assembly and Nucleosome Organization. J Biol Chem (2016) 0.75
A basic domain in the histone H2B N-terminal tail is important for nucleosome assembly by FACT. Nucleic Acids Res (2016) 0.75
The Structure-Specific Recognition Protein 1 Associates with Lens Epithelium-Derived Growth Factor Proteins and Modulates HIV-1 Replication. J Mol Biol (2016) 0.75
Fly Fishing for Histones: Catch and Release by Histone Chaperone Intrinsically Disordered Regions and Acidic Stretches. J Mol Biol (2017) 0.75
Residues in the Nucleosome Acidic Patch Regulate Histone Occupancy and Are Important for FACT Binding in Saccharomyces cerevisiae. Genetics (2017) 0.75
Forks on the Run: Can the Stalling of DNA Replication Promote Epigenetic Changes? Front Genet (2017) 0.75
Crystal structure of the nucleosome core particle at 2.8 A resolution. Nature (1997) 44.55
New DNA sequence rules for high affinity binding to histone octamer and sequence-directed nucleosome positioning. J Mol Biol (1998) 10.73
Preparation of nucleosome core particle from recombinant histones. Methods Enzymol (1999) 6.46
Histones: annotating chromatin. Annu Rev Genet (2009) 5.93
FACT facilitates transcription-dependent nucleosome alteration. Science (2003) 5.83
RNA polymerase II elongation factors of Saccharomyces cerevisiae: a targeted proteomics approach. Mol Cell Biol (2002) 5.04
FACT, a factor that facilitates transcript elongation through nucleosomes. Cell (1998) 4.91
The chromatin-specific transcription elongation factor FACT comprises human SPT16 and SSRP1 proteins. Nature (1999) 4.69
Reconstitution of nucleosome core particles from recombinant histones and DNA. Methods Enzymol (2004) 4.57
Nucleosomes are assembled by an acidic protein which binds histones and transfers them to DNA. Nature (1978) 4.56
High-mobility-group chromosomal proteins: architectural components that facilitate chromatin function. Prog Nucleic Acid Res Mol Biol (1996) 4.22
Expression and purification of recombinant histones and nucleosome reconstitution. Methods Mol Biol (1999) 4.22
Nucleosomes can form a polar barrier to transcript elongation by RNA polymerase II. Mol Cell (2006) 2.92
The histone chaperone Nap1 promotes nucleosome assembly by eliminating nonnucleosomal histone DNA interactions. Mol Cell (2010) 2.69
Higher-order structures of chromatin: the elusive 30 nm fiber. Cell (2007) 2.45
Mutations in SPT16/CDC68 suppress cis- and trans-acting mutations that affect promoter function in Saccharomyces cerevisiae. Mol Cell Biol (1991) 2.38
A new fluorescence resonance energy transfer approach demonstrates that the histone variant H2AZ stabilizes the histone octamer within the nucleosome. J Biol Chem (2004) 2.33
Histone chaperones: 30 years from isolation to elucidation of the mechanisms of nucleosome assembly and disassembly. Cell Mol Life Sci (2008) 2.12
CHD1 interacts with SSRP1 and depends on both its chromodomain and its ATPase/helicase-like domain for proper association with chromatin. Chromosoma (1999) 2.09
The Saccharomyces cerevisiae DNA polymerase alpha catalytic subunit interacts with Cdc68/Spt16 and with Pob3, a protein similar to an HMG1-like protein. Mol Cell Biol (1997) 2.03
CDC68, a yeast gene that affects regulation of cell proliferation and transcription, encodes a protein with a highly acidic carboxyl terminus. Mol Cell Biol (1991) 2.01
FACT-mediated exchange of histone variant H2AX regulated by phosphorylation of H2AX and ADP-ribosylation of Spt16. Mol Cell (2008) 1.99
A DNA damage-induced p53 serine 392 kinase complex contains CK2, hSpt16, and SSRP1. Mol Cell (2001) 1.88
yFACT induces global accessibility of nucleosomal DNA without H2A-H2B displacement. Mol Cell (2009) 1.85
Chromatin higher-order structure and dynamics. Cold Spring Harb Perspect Biol (2010) 1.81
The structure of the yFACT Pob3-M domain, its interaction with the DNA replication factor RPA, and a potential role in nucleosome deposition. Mol Cell (2006) 1.78
POB3 is required for both transcription and replication in the yeast Saccharomyces cerevisiae. Genetics (2000) 1.70
Characterization of the CP complex, an abundant dimer of Cdc68 and Pob3 proteins that regulates yeast transcriptional activation and chromatin repression. J Biol Chem (1998) 1.57
Nucleosome assembly. Nature (1980) 1.56
The FACT Spt16 "peptidase" domain is a histone H3-H4 binding module. Proc Natl Acad Sci U S A (2008) 1.50
A DNA unwinding factor involved in DNA replication in cell-free extracts of Xenopus eggs. Curr Biol (1999) 1.43
Structural and functional analysis of the Spt16p N-terminal domain reveals overlapping roles of yFACT subunits. J Biol Chem (2007) 1.38
A thermodynamic model for Nap1-histone interactions. J Biol Chem (2008) 1.36
Assembly of defined nucleosomal and chromatin arrays from pure components. Methods Enzymol (1999) 1.36
Dynamics of nucleosome invasion by DNA binding proteins. J Mol Biol (2011) 1.35
Multiple Nhp6 molecules are required to recruit Spt16-Pob3 to form yFACT complexes and to reorganize nucleosomes. J Biol Chem (2003) 1.35
The histone chaperone FACT: structural insights and mechanisms for nucleosome reorganization. J Biol Chem (2011) 1.34
FACT and the reorganized nucleosome. Mol Biosyst (2008) 1.33
The N-terminal domains of histones H3 and H4 are not necessary for chromatin assembly factor-1- mediated nucleosome assembly onto replicated DNA in vitro. Proc Natl Acad Sci U S A (2000) 1.28
p53 serine 392 phosphorylation increases after UV through induction of the assembly of the CK2.hSPT16.SSRP1 complex. J Biol Chem (2002) 1.27
The yeast protein complex containing cdc68 and pob3 mediates core-promoter repression through the cdc68 N-terminal domain. Genetics (1998) 1.26
Structural analysis of the RSC chromatin-remodeling complex. Proc Natl Acad Sci U S A (2002) 1.25
Nuclear chaperones. Semin Cell Dev Biol (2000) 1.23
Modulation of nucleosome-binding activity of FACT by poly(ADP-ribosyl)ation. Nucleic Acids Res (2006) 1.18
Reconstitution of chromatin: assembly of the nucleosome. Nucleic Acids Res (1978) 1.17
Histone Sin mutations promote nucleosome traversal and histone displacement by RNA polymerase II. EMBO Rep (2010) 1.15
Insight into the mechanism of nucleosome reorganization from histone mutants that suppress defects in the FACT histone chaperone. Genetics (2011) 1.11
Spectroscopic studies on histone-DNA interactions. II. Three transitions in nucleosomes resolved by salt-titration. J Mol Biol (1987) 1.04
Structural constraints in collaborative competition of transcription factors against the nucleosome. J Mol Biol (2011) 1.03
Phosphorylated intrinsically disordered region of FACT masks its nucleosomal DNA binding elements. J Biol Chem (2009) 1.01
Physicochemical analysis of electrostatic foundation for DNA-protein interactions in chromatin transformations. Prog Biophys Mol Biol (2006) 0.91
Techniques used to study transcription on chromatin templates. Methods Enzymol (2004) 0.87
Salt-dependent compaction of di- and trinucleosomes studied by small-angle neutron scattering. Biophys J (2000) 0.84
Solvent mediated interactions in the structure of the nucleosome core particle at 1.9 a resolution. J Mol Biol (2002) 8.42
Reconstitution of nucleosome core particles from recombinant histones and DNA. Methods Enzymol (2004) 4.57
Structural determinants for generating centromeric chromatin. Nature (2004) 4.25
The nucleosomal surface as a docking station for Kaposi's sarcoma herpesvirus LANA. Science (2006) 3.46
The histone chaperone Nap1 promotes nucleosome assembly by eliminating nonnucleosomal histone DNA interactions. Mol Cell (2010) 2.69
H2A.Z alters the nucleosome surface to promote HP1alpha-mediated chromatin fiber folding. Mol Cell (2004) 2.63
The essential histone variant H2A.Z regulates the equilibrium between different chromatin conformational states. Nat Struct Biol (2002) 2.63
B2 RNA binds directly to RNA polymerase II to repress transcript synthesis. Nat Struct Mol Biol (2004) 2.59
A new fluorescence resonance energy transfer approach demonstrates that the histone variant H2AZ stabilizes the histone octamer within the nucleosome. J Biol Chem (2004) 2.33
The structure of nucleosome assembly protein 1. Proc Natl Acad Sci U S A (2006) 2.13
Histone chaperones in nucleosome eviction and histone exchange. Curr Opin Struct Biol (2008) 2.09
Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions. EMBO J (2004) 2.08
Nucleosome assembly protein 1 exchanges histone H2A-H2B dimers and assists nucleosome sliding. J Biol Chem (2004) 2.08
A charged and contoured surface on the nucleosome regulates chromatin compaction. Nat Struct Mol Biol (2007) 1.95
Histone chaperones and nucleosome assembly. Curr Opin Struct Biol (2003) 1.94
The core histone N-terminal tail domains function independently and additively during salt-dependent oligomerization of nucleosomal arrays. J Biol Chem (2005) 1.91
Structural characterization of the histone variant macroH2A. Mol Cell Biol (2005) 1.85
Nucleosome-binding affinity as a primary determinant of the nuclear mobility of the pioneer transcription factor FoxA. Genes Dev (2009) 1.82
The effect of H3K79 dimethylation and H4K20 trimethylation on nucleosome and chromatin structure. Nat Struct Mol Biol (2008) 1.73
Nucleosomes containing the histone variant H2A.Bbd organize only 118 base pairs of DNA. EMBO J (2004) 1.67
Structure and function of nucleosome assembly proteins. Biochem Cell Biol (2006) 1.64
Crystal structures of nucleosome core particles in complex with minor groove DNA-binding ligands. J Mol Biol (2003) 1.63
Preferential binding of the histone (H3-H4)2 tetramer by NAP1 is mediated by the amino-terminal histone tails. J Biol Chem (2003) 1.56
Nucleosome accessibility governed by the dimer/tetramer interface. Nucleic Acids Res (2010) 1.55
Nucleosome core particles containing a poly(dA.dT) sequence element exhibit a locally distorted DNA structure. J Mol Biol (2006) 1.52
Structure and Scm3-mediated assembly of budding yeast centromeric nucleosomes. Nat Commun (2011) 1.46
Nucleosome structure(s) and stability: variations on a theme. Annu Rev Biophys (2011) 1.43
Histone chaperone specificity in Rtt109 activation. Nat Struct Mol Biol (2008) 1.42
A thermodynamic model for Nap1-histone interactions. J Biol Chem (2008) 1.36
The histone chaperone FACT: structural insights and mechanisms for nucleosome reorganization. J Biol Chem (2011) 1.34
Replacement of histone H3 with CENP-A directs global nucleosome array condensation and loosening of nucleosome superhelical termini. Proc Natl Acad Sci U S A (2011) 1.33
Histone chaperone FACT action during transcription through chromatin by RNA polymerase II. Proc Natl Acad Sci U S A (2013) 1.32
Structural and biophysical studies of human PARP-1 in complex with damaged DNA. J Mol Biol (2009) 1.31
Molecular recognition of the nucleosomal "supergroove". Proc Natl Acad Sci U S A (2004) 1.25
Yeast CAF-1 assembles histone (H3-H4)2 tetramers prior to DNA deposition. Nucleic Acids Res (2012) 1.18
The DEK oncoprotein is a Su(var) that is essential to heterochromatin integrity. Genes Dev (2011) 1.17
Fluorescence strategies for high-throughput quantification of protein interactions. Nucleic Acids Res (2011) 1.16
The histone variant macro-H2A preferentially forms "hybrid nucleosomes". J Biol Chem (2006) 1.12
p300-mediated tax transactivation from recombinant chromatin: histone tail deletion mimics coactivator function. Mol Cell Biol (2002) 1.12
The role of the nucleosome acidic patch in modulating higher order chromatin structure. J R Soc Interface (2013) 1.12
Evidence for monomeric actin function in INO80 chromatin remodeling. Nat Struct Mol Biol (2013) 1.12
Structural characterization of H3K56Q nucleosomes and nucleosomal arrays. Biochim Biophys Acta (2010) 1.12
Biophysical analysis and small-angle X-ray scattering-derived structures of MeCP2-nucleosome complexes. Nucleic Acids Res (2011) 1.11
Blocking transcription through a nucleosome with synthetic DNA ligands. J Mol Biol (2002) 1.11
Tax recruitment of CBP/p300, via the KIX domain, reveals a potent requirement for acetyltransferase activity that is chromatin dependent and histone tail independent. Mol Cell Biol (2003) 1.09
Torque modulates nucleosome stability and facilitates H2A/H2B dimer loss. Nat Commun (2013) 1.07
Structure of the Drosophila nucleosome core particle highlights evolutionary constraints on the H2A-H2B histone dimer. Proteins (2008) 1.07
A beta-hairpin comprising the nuclear localization sequence sustains the self-associated states of nucleosome assembly protein 1. J Mol Biol (2007) 1.06
CAL1 is the Drosophila CENP-A assembly factor. J Cell Biol (2014) 1.05
Structure and dynamic properties of nucleosome core particles. FEBS Lett (2005) 1.04
Molecular functions of the TLE tetramerization domain in Wnt target gene repression. EMBO J (2014) 1.02
Kaposi's sarcoma-associated herpesvirus LANA hitches a ride on the chromosome. Cell Cycle (2006) 1.01
Structure of Actin-related protein 8 and its contribution to nucleosome binding. Nucleic Acids Res (2012) 1.01
Chaperone Nap1 shields histone surfaces used in a nucleosome and can put H2A-H2B in an unconventional tetrameric form. Mol Cell (2013) 1.00
Structure and dynamics of nucleosomal DNA. Biopolymers (2003) 1.00
Understanding histone acetyltransferase Rtt109 structure and function: how many chaperones does it take? Curr Opin Struct Biol (2011) 0.98
Nucleosomes in solution exist as a mixture of twist-defect states. J Mol Biol (2005) 0.98
Histone chaperones, histone acetylation, and the fluidity of the chromogenome. J Cell Physiol (2010) 0.97
Alternative modes of binding of poly(ADP-ribose) polymerase 1 to free DNA and nucleosomes. J Biol Chem (2012) 0.97
A feed-forward repression mechanism anchors the Sin3/histone deacetylase and N-CoR/SMRT corepressors on chromatin. Mol Cell Biol (2006) 0.96
Deconstructing the late phase of vimentin assembly by total internal reflection fluorescence microscopy (TIRFM). PLoS One (2011) 0.93
Linker histone H1.0 interacts with an extensive network of proteins found in the nucleolus. Nucleic Acids Res (2013) 0.92
The linker region of macroH2A promotes self-association of nucleosomal arrays. J Biol Chem (2011) 0.91
Quantifying chromatin-associated interactions: the HI-FI system. Methods Enzymol (2012) 0.91
Defined structural changes occur in a nucleosome upon Amt1 transcription factor binding. J Mol Biol (2004) 0.89
Stability of nucleosomes containing homogenously ubiquitylated H2A and H2B prepared using semisynthesis. J Am Chem Soc (2012) 0.88
RNF4 interacts with both SUMO and nucleosomes to promote the DNA damage response. EMBO Rep (2014) 0.87
Assembly of nucleosomal arrays from recombinant core histones and nucleosome positioning DNA. J Vis Exp (2013) 0.87
A coupled equilibrium approach to study nucleosome thermodynamics. Methods Enzymol (2011) 0.85
The temperature of flash-cooling has dramatic effects on the diffraction quality of nucleosome crystals. Acta Crystallogr D Biol Crystallogr (2005) 0.85
A positive spin on the centromere. Cell (2009) 0.83
Closing the gap between single molecule and bulk FRET analysis of nucleosomes. PLoS One (2013) 0.81
The transcription factor Spn1 regulates gene expression via a highly conserved novel structural motif. J Mol Biol (2010) 0.81
Rise of the molecular machines. Curr Opin Struct Biol (2010) 0.78
Effects of photochemically activated alkylating agents of the FR900482 family on chromatin. Chem Biol (2007) 0.78
The tail does not always wag the dog. Nat Genet (2002) 0.76
Proteins for packaging, partitioning, processing, and proofing of nucleic acids. Curr Opin Struct Biol (2012) 0.75
Methods to characterize the effect of DNA-modifying compounds on nucleosomal DNA. Methods Mol Biol (2010) 0.75