Published in Arthritis Res Ther on January 01, 2006
Recent developments in the immunobiology of rheumatoid arthritis. Arthritis Res Ther (2008) 1.14
Is CD69 an effective brake to control inflammatory diseases? Trends Mol Med (2013) 1.06
Interleukin 15 levels in serum may predict a severe disease course in patients with early arthritis. PLoS One (2011) 1.04
Osteoclastogenesis and arthritis. Clin Exp Med (2010) 0.93
Inhibition of tumour necrosis factor and IL-17 production by leflunomide involves the JAK/STAT pathway. Ann Rheum Dis (2008) 0.87
CD48 on hematopoietic progenitors regulates stem cells and suppresses tumor formation. Blood (2011) 0.87
Biomarkers predicting a need for intensive treatment in patients with early arthritis. Curr Pharm Des (2015) 0.83
Astrocyte-derived interleukin-15 exacerbates ischemic brain injury via propagation of cellular immunity. Proc Natl Acad Sci U S A (2016) 0.81
Membrane bound IL-15 is increased on CD14 monocytes in early stages of MS. J Neuroimmunol (2008) 0.78
Interleukin-15-activated natural killer cells kill autologous osteoclasts via LFA-1, DNAM-1 and TRAIL, and inhibit osteoclast-mediated bone erosion in vitro. Immunology (2015) 0.75
Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis. N Engl J Med (2004) 14.53
Evolving concepts of rheumatoid arthritis. Nature (2003) 14.31
Cytokine pathways and joint inflammation in rheumatoid arthritis. N Engl J Med (2001) 7.41
Reciprocal activating interaction between natural killer cells and dendritic cells. J Exp Med (2002) 4.67
Treatment of rheumatoid arthritis with recombinant human interleukin-1 receptor antagonist. Arthritis Rheum (1998) 4.37
Development of anti-TNF therapy for rheumatoid arthritis. Nat Rev Immunol (2002) 4.37
Interleukin-15 mediates T cell-dependent regulation of tumor necrosis factor-alpha production in rheumatoid arthritis. Nat Med (1997) 4.03
Contact-dependent stimulation and inhibition of dendritic cells by natural killer cells. J Exp Med (2002) 3.35
Targeting interleukin-15 in patients with rheumatoid arthritis: a proof-of-concept study. Arthritis Rheum (2005) 2.37
VLA-3: a novel polypeptide association within the VLA molecular complex: cell distribution and biochemical characterization. Eur J Immunol (1986) 2.31
The role of T cells in the immunopathogenesis of rheumatoid arthritis: new perspectives. Arthritis Rheum (1997) 2.07
Phenotypic analysis of synovial tissue and peripheral blood lymphocytes isolated from patients with rheumatoid arthritis. Arthritis Rheum (1988) 1.90
CD56bright NK cells are enriched at inflammatory sites and can engage with monocytes in a reciprocal program of activation. J Immunol (2004) 1.78
Human monocytes constitutively express membrane-bound, biologically active, and interferon-gamma-upregulated interleukin-15. Blood (1999) 1.71
Activating interactions in human NK cell recognition: the role of 2B4-CD48. Eur J Immunol (1999) 1.62
Cytokine stimulation of T lymphocytes regulates their capacity to induce monocyte production of tumor necrosis factor-alpha, but not interleukin-10: possible relevance to pathophysiology of rheumatoid arthritis. Eur J Immunol (1997) 1.54
Role of the CD40-CD40 ligand interaction in CD4+ T cell contact-dependent activation of monocyte interleukin-1 synthesis. Eur J Immunol (1994) 1.37
Direct contact between T lymphocytes and monocytes is a major pathway for induction of metalloproteinase expression. J Biol Chem (1994) 1.36
Cell surface glycoproteins expressed on activated human T cells induce production of interleukin-1 beta by monocytic cells: a possible role of CD69. Eur Cytokine Netw (1993) 1.26
IL-15 and the initiation of cell contact-dependent synovial fibroblast-T lymphocyte cross-talk in rheumatoid arthritis: effect of methotrexate. J Immunol (2004) 1.25
Serum interleukin-12, interleukin-15, soluble CD26, and adenosine deaminase in patients with rheumatoid arthritis. Rheumatol Int (2001) 1.01
The role of innate mediators in inflammatory response. Mol Immunol (2002) 0.95
Very late activation antigen on synovial fluid T cells from patients with rheumatoid arthritis and other rheumatic diseases. Arthritis Rheum (1989) 0.93
Increased serum levels of interleukin-15 in rheumatoid arthritis with long- term disease. Clin Exp Rheumatol (2003) 0.93
Structure-function relationship and immunochemical mapping of external and intracellular antigenic sites on the lymphocyte activation inducer molecule, AIM/CD69. Eur J Immunol (1991) 0.91
2B4 co-stimulation: NK cells and their control of adaptive immune responses. Mol Immunol (2005) 0.89
CD69 expression on lymphocytes and interleukin-15 levels in synovial fluids from different inflammatory arthropathies. Rheumatol Int (2002) 0.89
SLAM Family Receptors Regulate Immunity with and without SAP-related Adaptors. J Exp Med (2004) 0.82
Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. Nat Commun (2011) 5.95
Peritoneal dialysis and epithelial-to-mesenchymal transition of mesothelial cells. N Engl J Med (2003) 5.01
Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8alpha+ dendritic cells. J Exp Med (2010) 3.84
Myeloid C-type lectins in innate immunity. Nat Immunol (2006) 3.41
Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation. PLoS Biol (2012) 3.18
Recruitment of Nck by CD3 epsilon reveals a ligand-induced conformational change essential for T cell receptor signaling and synapse formation. Cell (2002) 2.94
CD69 is an immunoregulatory molecule induced following activation. Trends Immunol (2005) 2.83
Tetraspanin-enriched microdomains: a functional unit in cell plasma membranes. Trends Cell Biol (2009) 2.82
F-actin is an evolutionarily conserved damage-associated molecular pattern recognized by DNGR-1, a receptor for dead cells. Immunity (2012) 2.72
HDAC6: a key regulator of cytoskeleton, cell migration and cell-cell interactions. Trends Cell Biol (2008) 2.71
Intercellular communication: diverse structures for exchange of genetic information. Nat Rev Mol Cell Biol (2012) 2.28
Role of the cytoskeleton during leukocyte responses. Nat Rev Immunol (2004) 2.11
The human C-type lectin CLECSF8 is a novel monocyte/macrophage endocytic receptor. Eur J Immunol (2004) 1.85
HDAC6 deacetylase activity links the tubulin cytoskeleton with immune synapse organization. Immunity (2004) 1.82
Endothelial adhesion receptors are recruited to adherent leukocytes by inclusion in preformed tetraspanin nanoplatforms. J Cell Biol (2008) 1.75
MTOC translocation modulates IS formation and controls sustained T cell signaling. J Cell Biol (2008) 1.75
ITAM-based interaction of ERM proteins with Syk mediates signaling by the leukocyte adhesion receptor PSGL-1. Immunity (2002) 1.73
The dendritic cell receptor DNGR-1 controls endocytic handling of necrotic cell antigens to favor cross-priming of CTLs in virus-infected mice. J Clin Invest (2012) 1.69
In vivo modulation of the inflammatory response by nonsteroidal antiinflammatory drug-related compounds that trigger L-selectin shedding. Eur J Immunol (2012) 1.63
Angiogenesis in chronic inflammatory liver disease. Hepatology (2004) 1.57
Endothelial tetraspanin microdomains regulate leukocyte firm adhesion during extravasation. Blood (2004) 1.56
DNGR-1 is a specific and universal marker of mouse and human Batf3-dependent dendritic cells in lymphoid and nonlymphoid tissues. Blood (2012) 1.56
The DC receptor DNGR-1 mediates cross-priming of CTLs during vaccinia virus infection in mice. J Clin Invest (2012) 1.52
EWI-2 and EWI-F link the tetraspanin web to the actin cytoskeleton through their direct association with ezrin-radixin-moesin proteins. J Biol Chem (2006) 1.50
ECM regulates MT1-MMP localization with beta1 or alphavbeta3 integrins at distinct cell compartments modulating its internalization and activity on human endothelial cells. J Cell Biol (2002) 1.48
Tetraspanins CD9 and CD81 modulate HIV-1-induced membrane fusion. J Immunol (2006) 1.48
The B7 homolog butyrophilin BTN2A1 is a novel ligand for DC-SIGN. J Immunol (2007) 1.47
Increased circulating pro-inflammatory cytokines and Th17 lymphocytes in Hashimoto's thyroiditis. J Clin Endocrinol Metab (2009) 1.45
The metalloprotease ADAM8 is associated with and regulates the function of the adhesion receptor PSGL-1 through ERM proteins. Eur J Immunol (2011) 1.45
Clinical features and 123I-FP-CIT SPECT imaging in vascular parkinsonism and Parkinson's disease. J Neurol Neurosurg Psychiatry (2012) 1.44
Specific targeting of human inflamed endothelium and in situ vascular tissue transfection by the use of ultrasound contrast agents. JACC Cardiovasc Imaging (2009) 1.42
CD69 downregulates autoimmune reactivity through active transforming growth factor-beta production in collagen-induced arthritis. J Clin Invest (2003) 1.41
Cutting edge: dynamic redistribution of tetraspanin CD81 at the central zone of the immune synapse in both T lymphocytes and APC. J Immunol (2002) 1.41
Membrane type 1-matrix metalloproteinase is involved in migration of human monocytes and is regulated through their interaction with fibronectin or endothelium. Blood (2005) 1.40
Caveolae are a novel pathway for membrane-type 1 matrix metalloproteinase traffic in human endothelial cells. Mol Biol Cell (2003) 1.39
Histone deacetylase 6 regulates human immunodeficiency virus type 1 infection. Mol Biol Cell (2005) 1.37
Moesin is required for HIV-1-induced CD4-CXCR4 interaction, F-actin redistribution, membrane fusion and viral infection in lymphocytes. J Cell Sci (2008) 1.35
In situ analysis of tyrosine phosphorylation networks by FLIM on cell arrays. Nat Methods (2010) 1.34
Global analysis of time correlated single photon counting FRET-FLIM data. Opt Express (2009) 1.34
VLA-4 integrin concentrates at the peripheral supramolecular activation complex of the immune synapse and drives T helper 1 responses. Proc Natl Acad Sci U S A (2004) 1.31
Enhanced antitumor immunity in mice deficient in CD69. J Exp Med (2003) 1.29
Lymphocyte chemotaxis is regulated by histone deacetylase 6, independently of its deacetylase activity. Mol Biol Cell (2006) 1.29
Regulated expression of the pathogen receptor dendritic cell-specific intercellular adhesion molecule 3 (ICAM-3)-grabbing nonintegrin in THP-1 human leukemic cells, monocytes, and macrophages. J Biol Chem (2004) 1.28
Role of the von Hippel-Lindau tumor suppressor gene in the formation of beta1-integrin fibrillar adhesions. Cancer Res (2002) 1.27
Relevance of CD6-mediated interactions in T cell activation and proliferation. J Immunol (2004) 1.27
Interferon-β production via Dectin-1-Syk-IRF5 signaling in dendritic cells is crucial for immunity to C. albicans. Immunity (2013) 1.27
Functional insights on the polarized redistribution of leukocyte integrins and their ligands during leukocyte migration and immune interactions. Immunol Rev (2007) 1.26
CD69: an unexpected regulator of TH17 cell-driven inflammatory responses. Sci Signal (2011) 1.26
Transfer of extracellular vesicles during immune cell-cell interactions. Immunol Rev (2013) 1.25
Regulation of microtubule-organizing center orientation and actomyosin cytoskeleton rearrangement during immune interactions. Immunol Rev (2002) 1.25
Candida albicans internalization by host cells is mediated by a clathrin-dependent mechanism. Cell Microbiol (2009) 1.24
Chemokine receptors that mediate B cell homing to secondary lymphoid tissues are highly expressed in B cell chronic lymphocytic leukemia and non-Hodgkin lymphomas with widespread nodular dissemination. J Leukoc Biol (2004) 1.23
Role of Fyn in the rearrangement of tubulin cytoskeleton induced through TCR. J Immunol (2006) 1.20
Myosin IIA is involved in the endocytosis of CXCR4 induced by SDF-1alpha. J Cell Sci (2007) 1.20
The mitochondrial fission factor dynamin-related protein 1 modulates T-cell receptor signalling at the immune synapse. EMBO J (2011) 1.19
Molecular cues guiding inflammatory responses. Cardiovasc Res (2010) 1.19
A novel serine-rich motif in the intercellular adhesion molecule 3 is critical for its ezrin/radixin/moesin-directed subcellular targeting. J Biol Chem (2002) 1.17
The rho exchange factors vav2 and vav3 control a lung metastasis-specific transcriptional program in breast cancer cells. Sci Signal (2012) 1.17
CD69 association with Jak3/Stat5 proteins regulates Th17 cell differentiation. Mol Cell Biol (2010) 1.17
CLEC-2 signaling via Syk in myeloid cells can regulate inflammatory responses. Eur J Immunol (2011) 1.16
A juxta-membrane amino acid sequence of P-selectin glycoprotein ligand-1 is involved in moesin binding and ezrin/radixin/moesin-directed targeting at the trailing edge of migrating lymphocytes. Eur J Immunol (2002) 1.14
Regulatory T cells in human autoimmune thyroid disease. J Clin Endocrinol Metab (2006) 1.14
G protein-coupled receptor kinase 2 positively regulates epithelial cell migration. EMBO J (2008) 1.14
Endothelial nitric oxide synthase regulates T cell receptor signaling at the immunological synapse. Immunity (2006) 1.13
Role of ICAM-3 in the initial interaction of T lymphocytes and APCs. Nat Immunol (2002) 1.13
Recruitment of transferrin receptor to immunological synapse in response to TCR engagement. J Immunol (2004) 1.12
Efficient and versatile manipulation of the peripheral CD4+ T-cell compartment by antigen targeting to DNGR-1/CLEC9A. Eur J Immunol (2010) 1.12
Expression and regulation of the metalloproteinase ADAM-8 during human neutrophil pathophysiological activation and its catalytic activity on L-selectin shedding. J Immunol (2007) 1.11
The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. J Biol Chem (2013) 1.10
Synaptic clusters of MHC class II molecules induced on DCs by adhesion molecule-mediated initial T-cell scanning. Mol Biol Cell (2005) 1.10
CD69 limits the severity of cardiomyopathy after autoimmune myocarditis. Circulation (2010) 1.09
The accessory molecules CD5 and CD6 associate on the membrane of lymphoid T cells. J Biol Chem (2002) 1.09
Selective induction of expression of a ligand for the NKG2D receptor by proteasome inhibitors. Cancer Res (2008) 1.09
Macrophage oxygen sensing modulates antigen presentation and phagocytic functions involving IFN-gamma production through the HIF-1 alpha transcription factor. J Immunol (2009) 1.07
Role of tetraspanins CD9 and CD151 in primary melanocyte motility. J Invest Dermatol (2005) 1.07
Is CD69 an effective brake to control inflammatory diseases? Trends Mol Med (2013) 1.06
Selective inactivation of p27(Kip1) in hematopoietic progenitor cells increases neointimal macrophage proliferation and accelerates atherosclerosis. Blood (2003) 1.06
Contribution of N-linked glycans to the conformation and function of intercellular adhesion molecules (ICAMs). J Biol Chem (2004) 1.05
Molecular basis of leukocyte-endothelium interactions during the inflammatory response. Rev Esp Cardiol (2009) 1.05
MT1-MMP collagenolytic activity is regulated through association with tetraspanin CD151 in primary endothelial cells. Blood (2008) 1.05
A role for the Rho-p160 Rho coiled-coil kinase axis in the chemokine stromal cell-derived factor-1alpha-induced lymphocyte actomyosin and microtubular organization and chemotaxis. J Immunol (2002) 1.05
HIF2α acts as an mTORC1 activator through the amino acid carrier SLC7A5. Mol Cell (2012) 1.05
Cutting edge: association of the motor protein nonmuscle myosin heavy chain-IIA with the C terminus of the chemokine receptor CXCR4 in T lymphocytes. J Immunol (2002) 1.05
Rapamycin attenuates atherosclerosis induced by dietary cholesterol in apolipoprotein-deficient mice through a p27 Kip1 -independent pathway. Atherosclerosis (2004) 1.05
Lipopolysaccharide and sphingosine-1-phosphate cooperate to induce inflammatory molecules and leukocyte adhesion in endothelial cells. J Immunol (2012) 1.05
Lipid rafts mediate biosynthetic transport to the T lymphocyte uropod subdomain and are necessary for uropod integrity and function. Blood (2002) 1.05
Functional role of P-selectin glycoprotein ligand 1/P-selectin interaction in the generation of tolerogenic dendritic cells. J Immunol (2007) 1.04
Miro-1 links mitochondria and microtubule Dynein motors to control lymphocyte migration and polarity. Mol Cell Biol (2014) 1.04
Signaling through the leukocyte integrin LFA-1 in T cells induces a transient activation of Rac-1 that is regulated by Vav and PI3K/Akt-1. J Biol Chem (2004) 1.04
Ligand-induced conformational change in the T-cell receptor associated with productive immune synapses. Blood (2005) 1.04