Published in J Biol Chem on May 12, 2006
The physiological significance of the cardiotonic steroid/ouabain-binding site of the Na,K-ATPase. Annu Rev Physiol (2010) 1.58
The Na/K-ATPase/Src complex and cardiotonic steroid-activated protein kinase cascades. Pflugers Arch (2008) 1.46
Cardiac glycosides inhibit p53 synthesis by a mechanism relieved by Src or MAPK inhibition. Cancer Res (2009) 1.27
Regulation of caveolin-1 membrane trafficking by the Na/K-ATPase. J Cell Biol (2008) 1.22
The sodium pump and cardiotonic steroids-induced signal transduction protein kinases and calcium-signaling microdomain in regulation of transporter trafficking. Biochim Biophys Acta (2010) 1.17
Changes in sodium pump expression dictate the effects of ouabain on cell growth. J Biol Chem (2009) 1.16
Digitoxin and its analogs as novel cancer therapeutics. Exp Hematol Oncol (2012) 1.06
NaKtide, a Na/K-ATPase-derived peptide Src inhibitor, antagonizes ouabain-activated signal transduction in cultured cells. J Biol Chem (2009) 1.04
Cardiac glycosides in cancer therapy: from preclinical investigations towards clinical trials. Invest New Drugs (2013) 1.04
A novel strategy to isolate ubiquitin conjugates reveals wide role for ubiquitination during neural development. Mol Cell Proteomics (2010) 0.99
Regulation of intracellular cholesterol distribution by Na/K-ATPase. J Biol Chem (2009) 0.99
Na/K-ATPase mimetic pNaKtide peptide inhibits the growth of human cancer cells. J Biol Chem (2011) 0.97
Elimination of autofluorescence background from fluorescence tissue images by use of time-gated detection and the AzaDiOxaTriAngulenium (ADOTA) fluorophore. Anal Bioanal Chem (2012) 0.96
Reduction of Na/K-ATPase potentiates marinobufagenin-induced cardiac dysfunction and myocyte apoptosis. J Biol Chem (2012) 0.95
Regulation of sodium pump endocytosis by cardiotonic steroids: Molecular mechanisms and physiological implications. Pathophysiology (2007) 0.95
Identification of a novel transport-independent function of PiT1/SLC20A1 in the regulation of TNF-induced apoptosis. J Biol Chem (2010) 0.93
Ouabain-stimulated trafficking regulation of the Na/K-ATPase and NHE3 in renal proximal tubule cells. Mol Cell Biochem (2012) 0.91
Identification of a potential receptor that couples ion transport to protein kinase activity. J Biol Chem (2010) 0.90
The polarized distribution of Na+,K+-ATPase: role of the interaction between {beta} subunits. Mol Biol Cell (2010) 0.90
Alterations of Na+/K+-ATPase function in caveolin-1 knockout cardiac fibroblasts. J Mol Cell Cardiol (2010) 0.90
Differential effects of Na+-K+ ATPase blockade on cortical layer V neurons. J Physiol (2010) 0.90
Role of SRC family kinase in extracellular renal cyclic guanosine 3',5'-monophosphate- and pressure-induced natriuresis. Hypertension (2011) 0.89
Involvement of reactive oxygen species in a feed-forward mechanism of Na/K-ATPase-mediated signaling transduction. J Biol Chem (2013) 0.89
Antiproliferative effect of sulindac in colonic neoplasia prevention: role of COOH-terminal Src kinase. Mol Cancer Ther (2008) 0.87
Ouabain stimulates Na-K-ATPase through a sodium/hydrogen exchanger-1 (NHE-1)-dependent mechanism in human kidney proximal tubule cells. Am J Physiol Renal Physiol (2010) 0.87
Activation of c-SRC underlies the differential effects of ouabain and digoxin on Ca(2+) signaling in arterial smooth muscle cells. Am J Physiol Cell Physiol (2012) 0.86
Na+/K+ ATPase regulates the expression and localization of acetylcholine receptors in a pump activity-independent manner. Mol Cell Neurosci (2008) 0.86
Sympathetic nerves and the endothelium influence the vasoconstrictor effect of low concentrations of ouabain in pressurized small arteries. Am J Physiol Heart Circ Physiol (2010) 0.86
The multifaceted mineralocorticoid receptor. Compr Physiol (2014) 0.85
Identification of a mutant α1 Na/K-ATPase that pumps but is defective in signal transduction. J Biol Chem (2013) 0.85
Knockout of the Na,K-ATPase α2-isoform in cardiac myocytes delays pressure overload-induced cardiac dysfunction. Am J Physiol Heart Circ Physiol (2013) 0.84
Cardiotonic steroids stabilize regulator of G protein signaling 2 protein levels. Mol Pharmacol (2012) 0.84
Extracellular galectin-3 programs multidrug resistance through Na+/K+-ATPase and P-glycoprotein signaling. Oncotarget (2015) 0.82
Expression of mutant α1 Na/K-ATPase defective in conformational transition attenuates Src-mediated signal transduction. J Biol Chem (2013) 0.82
Na/K-ATPase signaling regulates collagen synthesis through microRNA-29b-3p in cardiac fibroblasts. Physiol Genomics (2015) 0.80
Ouabain and insulin induce sodium pump endocytosis in renal epithelium. Hypertension (2012) 0.80
Regulation of alpha1 Na/K-ATPase expression by cholesterol. J Biol Chem (2011) 0.80
Pivotal role of α2 Na(+) pumps and their high affinity ouabain binding site in cardiovascular health and disease. J Physiol (2016) 0.79
Oxidized LDL-bound CD36 recruits an Na⁺/K⁺-ATPase-Lyn complex in macrophages that promotes atherosclerosis. Sci Signal (2015) 0.79
Somatic mutations of the ATP1A1 gene and aldosterone-producing adenomas. Mol Cell Endocrinol (2014) 0.78
Identification of hydroxyxanthones as Na/K-ATPase ligands. Mol Pharmacol (2010) 0.78
Expression of rat Na-K-ATPase α2 enables ion pumping but not ouabain-induced signaling in α1-deficient porcine renal epithelial cells. Am J Physiol Cell Physiol (2015) 0.78
Novel role of ouabain as a cystogenic factor in autosomal dominant polycystic kidney disease. Am J Physiol Renal Physiol (2013) 0.78
Regulation of renal function and structure by the signaling Na/K-ATPase. IUBMB Life (2013) 0.78
The Role of Na/K-ATPase Signaling in Oxidative Stress Related to Obesity and Cardiovascular Disease. Molecules (2016) 0.78
Formation of new high density glycogen-microtubule structures is induced by cardiac steroids. J Biol Chem (2012) 0.77
Specialized Functional Diversity and Interactions of the Na,K-ATPase. Front Physiol (2016) 0.76
The alpha1 isoform of the Na+/K+ ATPase is up-regulated in dedifferentiated progenitor cells that mediate lens and retina regeneration in adult newts. Exp Eye Res (2008) 0.76
Endogenous Ouabain: An Old Cardiotonic Steroid as a New Biomarker of Heart Failure and a Predictor of Mortality after Cardiac Surgery. Biomed Res Int (2015) 0.76
Src-independent ERK signaling through the α3 isoform of Na/K-ATPase. Am J Physiol Cell Physiol (2016) 0.75
Protein Carbonylation of an Amino Acid Residue of the Na/K-ATPase α1 Subunit Determines Na/K-ATPase Signaling and Sodium Transport in Renal Proximal Tubular Cells. J Am Heart Assoc (2016) 0.75
The Influence of Na(+), K(+)-ATPase on Glutamate Signaling in Neurodegenerative Diseases and Senescence. Front Physiol (2016) 0.75
EPEC effector EspF promotes Crumbs3 endocytosis and disrupts epithelial cell polarity. Cell Microbiol (2017) 0.75
Ouabain affects cell migration via Na,K-ATPase-p130cas and via nucleus-centrosome association. PLoS One (2017) 0.75
Bak regulates mitochondrial morphology and pathology during apoptosis by interacting with mitofusins. Proc Natl Acad Sci U S A (2007) 2.65
Na+-K+--ATPase-mediated signal transduction: from protein interaction to cellular function. Mol Interv (2003) 2.13
Binding of Src to Na+/K+-ATPase forms a functional signaling complex. Mol Biol Cell (2005) 1.92
Ouabain assembles signaling cascades through the caveolar Na+/K+-ATPase. J Biol Chem (2004) 1.71
Identification of a pool of non-pumping Na/K-ATPase. J Biol Chem (2007) 1.69
Mitochondrial potassium transport: the role of the mitochondrial ATP-sensitive K(+) channel in cardiac function and cardioprotection. Biochim Biophys Acta (2003) 1.67
Src-mediated inter-receptor cross-talk between the Na+/K+-ATPase and the epidermal growth factor receptor relays the signal from ouabain to mitogen-activated protein kinases. J Biol Chem (2002) 1.51
Overexpressing AtPAP15 enhances phosphorus efficiency in soybean. Plant Physiol (2009) 1.43
Na/K-ATPase tethers phospholipase C and IP3 receptor into a calcium-regulatory complex. Mol Biol Cell (2005) 1.36
Partial nephrectomy as a model for uremic cardiomyopathy in the mouse. Am J Physiol Renal Physiol (2007) 1.31
Regulation of caveolin-1 membrane trafficking by the Na/K-ATPase. J Cell Biol (2008) 1.22
Molecular epidemiology of measles viruses in China, 1995-2003. Virol J (2007) 1.20
The sodium pump and cardiotonic steroids-induced signal transduction protein kinases and calcium-signaling microdomain in regulation of transporter trafficking. Biochim Biophys Acta (2010) 1.17
Biochemical and molecular characterization of PvPAP3, a novel purple acid phosphatase isolated from common bean enhancing extracellular ATP utilization. Plant Physiol (2009) 1.12
Purification of endohedral trimetallic nitride fullerenes in a single, facile step. J Am Chem Soc (2005) 1.08
Positive inotropic effect of ouabain on isolated heart is accompanied by activation of signal pathways that link Na+/K+-ATPase to ERK1/2. J Cardiovasc Pharmacol (2003) 1.07
Na+/Ca2+ exchange and Na+/K+-ATPase in the heart. J Physiol (2015) 1.06
NaKtide, a Na/K-ATPase-derived peptide Src inhibitor, antagonizes ouabain-activated signal transduction in cultured cells. J Biol Chem (2009) 1.04
Prenatal and perinatal risk factors for autism in China. J Autism Dev Disord (2010) 1.04
Regulation of apical NHE3 trafficking by ouabain-induced activation of the basolateral Na+-K+-ATPase receptor complex. Am J Physiol Cell Physiol (2007) 0.99
Regulation of intracellular cholesterol distribution by Na/K-ATPase. J Biol Chem (2009) 0.99
Na/K-ATPase mimetic pNaKtide peptide inhibits the growth of human cancer cells. J Biol Chem (2011) 0.97
Low pH, aluminum, and phosphorus coordinately regulate malate exudation through GmALMT1 to improve soybean adaptation to acid soils. Plant Physiol (2013) 0.97
Allergenic pollen season variations in the past two decades under changing climate in the United States. Glob Chang Biol (2014) 0.96
Reduction of Na/K-ATPase potentiates marinobufagenin-induced cardiac dysfunction and myocyte apoptosis. J Biol Chem (2012) 0.95
High relaxivity trimetallic nitride (Gd3N) metallofullerene MRI contrast agents with optimized functionality. Bioconjug Chem (2010) 0.93
The high-affinity phosphate transporter GmPT5 regulates phosphate transport to nodules and nodulation in soybean. Plant Physiol (2012) 0.93
Regulation of longevity by genes required for the functions of AIY interneuron in nematode Caenorhabditis elegans. Mech Ageing Dev (2010) 0.92
Effect of insurance payer status on the surgical treatment of early stage breast cancer: data analysis from a single health system. JAMA Surg (2013) 0.91
Regulation of inositol 1,4,5-trisphosphate receptor-mediated calcium release by the Na/K-ATPase in cultured renal epithelial cells. J Biol Chem (2007) 0.91
Ouabain-stimulated trafficking regulation of the Na/K-ATPase and NHE3 in renal proximal tubule cells. Mol Cell Biochem (2012) 0.91
Identification of a potential receptor that couples ion transport to protein kinase activity. J Biol Chem (2010) 0.90
Alterations of Na+/K+-ATPase function in caveolin-1 knockout cardiac fibroblasts. J Mol Cell Cardiol (2010) 0.90
The size of mesenchymal stem cells is a significant cause of vascular obstructions and stroke. Stem Cell Rev (2014) 0.90
Evaluation of the effects of comprehensive reform on primary healthcare institutions in Anhui Province. BMC Health Serv Res (2014) 0.90
Identification and characterization of an expansin gene AsEXP1 associated with heat tolerance in C3 Agrostis grass species. J Exp Bot (2007) 0.89
Involvement of reactive oxygen species in a feed-forward mechanism of Na/K-ATPase-mediated signaling transduction. J Biol Chem (2013) 0.89
Identification of differentially expressed proteins in soybean nodules under phosphorus deficiency through proteomic analysis. Proteomics (2011) 0.87
Involvement of Na+/K+-ATPase in hydrogen peroxide-induced hypertrophy in cardiac myocytes. Free Radic Biol Med (2006) 0.87
Rotavirus-induced murine biliary atresia is mediated by nuclear factor-kappaB. J Pediatr Surg (2005) 0.86
Genes required for the functions of olfactory AWA neuron regulate the longevity of Caenorhabditis elegans in an insulin/IGF signaling-dependent fashion. Neurosci Bull (2010) 0.86
Identification of a PKCepsilon-dependent regulation of myocardial contraction by epicatechin-3-gallate. Am J Physiol Heart Circ Physiol (2007) 0.85
Identification of conserved and novel microRNAs in cashmere goat skin by deep sequencing. PLoS One (2012) 0.85
Passive immunization against marinobufagenin attenuates renal fibrosis and improves renal function in experimental renal disease. Am J Hypertens (2013) 0.84
Infection and replication of avian influenza H5N1 virus in an infected human. Virus Genes (2009) 0.84
Co-inoculation with rhizobia and AMF inhibited soybean red crown rot: from field study to plant defense-related gene expression analysis. PLoS One (2012) 0.84
Tea pigments inhibit the production of type 1 (T(H1)) and type 2 (T(H2)) helper T cell cytokines in CD4(+) T cells. Phytother Res (2002) 0.84
Aluminum nanoparticle exposure in L1 larvae results in more severe lethality toxicity than in L4 larvae or young adults by strengthening the formation of stress response and intestinal lipofuscin accumulation in nematodes. Environ Toxicol Pharmacol (2010) 0.82
Close association of intestinal autofluorescence with the formation of severe oxidative damage in intestine of nematodes chronically exposed to Al(2)O(3)-nanoparticle. Environ Toxicol Pharmacol (2011) 0.82
Frequency and spectrum of mitochondrial 12S rRNA variants in 440 Han Chinese hearing impaired pediatric subjects from two otology clinics. J Transl Med (2011) 0.81
Development of a novel genotype-specific loop-mediated isothermal amplification technique for Hepatitis B virus genotypes B and C genotyping and quantification. J Clin Virol (2011) 0.81
Comparative analysis of PvPAP gene family and their functions in response to phosphorus deficiency in common bean. PLoS One (2012) 0.81
Renal ischemia regulates marinobufagenin release in humans. Hypertension (2010) 0.80
Aluminium tolerance and high phosphorus efficiency helps Stylosanthes better adapt to low-P acid soils. Ann Bot (2009) 0.80
Regulation of alpha1 Na/K-ATPase expression by cholesterol. J Biol Chem (2011) 0.80
Characterization of two putative protein phosphatase genes and their involvement in phosphorus efficiency in Phaseolus vulgaris. J Integr Plant Biol (2012) 0.79
Low-concentration polymers inhibit and accelerate crystal growth in organic glasses in correlation with segmental mobility. J Phys Chem B (2013) 0.78
Superior aluminium (Al) tolerance of Stylosanthes is achieved mainly by malate synthesis through an Al-enhanced malic enzyme, SgME1. New Phytol (2013) 0.78
Influence of induced ciprofloxacin resistance on efflux pump activity of Klebsiella pneumoniae. J Zhejiang Univ Sci B (2013) 0.78
Identification of hydroxyxanthones as Na/K-ATPase ligands. Mol Pharmacol (2010) 0.78
[Prevalence of malaria in Liaoning Province, 2008 to 2013]. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi (2014) 0.78
Water self-diffusion in glassy and liquid maltose measured by Raman microscopy and NMR. J Phys Chem B (2011) 0.77
Proteomics dissection of plant responses to mineral nutrient deficiency. Proteomics (2013) 0.77
Cytomegalovirus glycoprotein B sequence variation in Chinese liver transplant recipients. Hepatobiliary Pancreat Dis Int (2002) 0.77
Highly regioselective derivatization of trimetallic nitride templated endohedral metallofullerenes via a facile photochemical reaction. J Am Chem Soc (2008) 0.76
Stability of amorphous pharmaceutical solids: crystal growth mechanisms and effect of polymer additives. AAPS J (2012) 0.76
[Design, synthesis and antiproliferative activities of artemisinin derivatives substituted by N-heterocycles]. Yao Xue Xue Bao (2015) 0.76
Manganese(III)-catalyzed free radical reactions on trimetallic nitride endohedral metallofullerenes. J Am Chem Soc (2007) 0.76
A protease-insensitive feruloyl esterase from China Holstein cow rumen metagenomic library: expression, characterization, and utilization in ferulic acid release from wheat straw. J Agric Food Chem (2012) 0.76
Signaling through the Na/K-ATPase: implications for cardiac fibrosis. Am J Physiol Heart Circ Physiol (2010) 0.75
Expression of messenger RNA for transforming growth factor-beta1 and for transforming growth factor-beta receptors in peripheral blood of immune thrombocytopenic purpura. Platelets (2012) 0.75
[Juvenile nasopharyngeal angiofibroma: endoscopic surgery and follow-up results]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi (2010) 0.75
[Isolation and characterization of two bacteria with heavy metal resistance and phosphate solubilizing capability]. Huan Jing Ke Xue (2014) 0.75
[Expression of transforming growth factor-β1 and its receptors in peripheral blood of patients with immune thrombocytopenic purpura]. Zhongguo Shi Yan Xue Ye Xue Za Zhi (2012) 0.75
[Establishment of fingerprint database for drug-resistant strain of Acinetobacter baumannii by AFLP method]. Zhejiang Da Xue Xue Bao Yi Xue Ban (2007) 0.75
Alemtuzumab Induction Is Associated With an Equalization of Outcomes Between White and African American Kidney Transplant Recipients. Exp Clin Transplant (2017) 0.75
[The strategies of endosomal escape for intracellular gene delivery]. Yao Xue Xue Bao (2014) 0.75
Simultaneous profiling of multiple gene-methylation loci by electrochemical methylation-specific ligase detection reaction. Chem Commun (Camb) (2013) 0.75
Acceleration of Crystal Growth of Amorphous Griseofulvin by Low-concentration Poly (ethylene oxide): Aspects of Crystallization Kinetics and Molecular Mobility. Mol Pharm (2017) 0.75
Selective Acceleration of Crystal Growth of Indomethacin Polymorphs by Low-Concentration Poly(ethylene oxide). Mol Pharm (2017) 0.75
[Hemihypertrophy: report of four cases]. Zhongguo Dang Dai Er Ke Za Zhi (2009) 0.75
[Effects of autologous peripheral stem cell transplantation on acoustic radiation force impulse in patients with HBV-related decompensated cirrhosis]. Zhonghua Gan Zang Bing Za Zhi (2015) 0.75
Corrigendum: Attenuation of Na/K-ATPase Mediated Oxidant Amplification with pNaKtide Ameliorates Experimental Uremic Cardiomyopathy. Sci Rep (2017) 0.75
[The relation between age and expression of Myosin VI and Disabled-2 in the cochlea of mice]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi (2015) 0.75
Anti-hepatitis B virus treatment guided by long-term virus kinetics stepwise tracing. J Gastroenterol Hepatol (2009) 0.75