Published in Science on January 25, 1991
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Sequence-specific DNA recognition by the thyroid transcription factor-1 homeodomain. Nucleic Acids Res (1994) 1.25
An autoregulatory element of the murine Hox-4.2 gene. EMBO J (1992) 1.22
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A universal target sequence is bound in vitro by diverse homeodomains. Mech Dev (1993) 1.20
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Functional differences between HOX proteins conferred by two residues in the homeodomain N-terminal arm. Mol Cell Biol (1994) 1.05
A novel murine homeobox gene isolated by a tissue specific PCR cloning strategy. Nucleic Acids Res (1992) 1.05
Reprogrammable recognition codes in bicoid homeodomain-DNA interaction. Mol Cell Biol (2000) 1.03
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The mating-type proteins of fission yeast induce meiosis by directly activating mei3 transcription. Mol Cell Biol (1998) 1.00
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Sequence-specific targeting of nuclear signal transduction pathways by homeodomain proteins. Mol Cell Biol (1995) 0.96
Nkx3.1 binds and negatively regulates the transcriptional activity of Sp-family members in prostate-derived cells. Biochem J (2006) 0.95
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From sequence to structure and back again: approaches for predicting protein-DNA binding. Proteome Sci (2004) 0.93
Analysis of a fushi tarazu autoregulatory element: multiple sequence elements contribute to enhancer activity. EMBO J (1993) 0.93
DNA-binding specificity of the S8 homeodomain. Nucleic Acids Res (1993) 0.91
A proline-rich transcriptional activation domain in murine HOXD-4 (HOX-4.2). Nucleic Acids Res (1994) 0.90
A phage display selection of engrailed homeodomain mutants and the importance of residue Q50. Nucleic Acids Res (2004) 0.89
The optimal binding sequence of the Hox11 protein contains a predicted recognition core motif. Nucleic Acids Res (1995) 0.89
Mutation of a single lysine residue severely impairs the DNA recognition and regulatory functions of the VZV gene 62 transactivator protein. Nucleic Acids Res (1994) 0.88
The Drosophila copia retrotransposon contains binding sites for transcriptional regulation by homeoproteins. Nucleic Acids Res (1993) 0.87
Vsx2 controls eye organogenesis and retinal progenitor identity via homeodomain and non-homeodomain residues required for high affinity DNA binding. PLoS Genet (2012) 0.85
Isolation and characterization of the chicken homeodomain protein AKR. Nucleic Acids Res (1995) 0.84
Exploring the DNA-recognition potential of homeodomains. Genome Res (2012) 0.83
Characterization of Hoxd1 protein-DNA-binding specificity using affinity chromatography and random DNA oligomer selection. Cell Mol Neurobiol (2001) 0.82
A cis-regulatory signature for chordate anterior neuroectodermal genes. PLoS Genet (2010) 0.80
SpGataE, a Strongylocentrotus purpuratus ortholog of mammalian Gata4/5/6: protein expression, interaction with putative target gene spec2a, and identification of friend of Gata factor SpFog1. Dev Genes Evol (2007) 0.79
Study of intermolecular contacts in the proline-rich homeodomain (PRH)-DNA complex using molecular dynamics simulations. Eur Biophys J (2012) 0.78
Structure, regulation, and function of micro1 in the sea urchin Hemicentrotus pulcherrimus. Dev Genes Evol (2004) 0.77
In the TTF-1 homeodomain the contribution of several amino acids to DNA recognition depends on the bound sequence. Nucleic Acids Res (1996) 0.76
Functional analysis of mouse Hoxa-7 in Saccharomyces cerevisiae: sequences outside the homeodomain base contact zone influence binding and activation. Mol Cell Biol (1994) 0.76
Study of base pair mutations in proline-rich homeodomain (PRH)-DNA complexes using molecular dynamics. Eur Biophys J (2013) 0.75
Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2. Cell (1993) 15.70
A eukaryotic transcriptional activator bearing the DNA specificity of a prokaryotic repressor. Cell (1985) 8.30
Mxi1, a protein that specifically interacts with Max to bind Myc-Max recognition sites. Cell (1993) 6.40
Mechanism of action of the lexA gene product. Proc Natl Acad Sci U S A (1981) 6.13
DNA specificity of the bicoid activator protein is determined by homeodomain recognition helix residue 9. Cell (1989) 5.89
Modelling cellular behaviour. Nature (2001) 5.85
Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins. Cell (1994) 4.95
Correlation of two-hybrid affinity data with in vitro measurements. Mol Cell Biol (1995) 4.63
A bacterial repressor protein or a yeast transcriptional terminator can block upstream activation of a yeast gene. Nature (1985) 4.08
APC binds to the novel protein EB1. Cancer Res (1995) 3.98
Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor. Mol Endocrinol (1995) 3.59
DNA-bound Fos proteins activate transcription in yeast. Cell (1988) 3.22
Interaction mating reveals binary and ternary connections between Drosophila cell cycle regulators. Proc Natl Acad Sci U S A (1994) 3.18
The lexA gene product represses its own promoter. Proc Natl Acad Sci U S A (1980) 3.03
Fused protein domains inhibit DNA binding by LexA. Mol Cell Biol (1992) 3.01
Rch1, a protein that specifically interacts with the RAG-1 recombination-activating protein. Proc Natl Acad Sci U S A (1994) 2.86
Yeast Cbk1 and Mob2 activate daughter-specific genetic programs to induce asymmetric cell fates. Cell (2001) 2.76
Protein interaction methods--toward an endgame. Science (1999) 2.48
Genetic selection of peptide aptamers that recognize and inhibit cyclin-dependent kinase 2. Nature (1996) 2.34
LexA protein is a repressor of the colicin E1 gene. J Biol Chem (1983) 2.24
Oncogenic transformation by vrel requires an amino-terminal activation domain. Mol Cell Biol (1990) 2.15
Regulation of damage-inducible genes in Escherichia coli. J Mol Biol (1982) 1.63
Repression of transcription in yeast. Cell (1985) 1.53
Gene activation and DNA binding by Drosophila Ubx and abd-A proteins. Cell (1989) 1.53
Mxi2, a mitogen-activated protein kinase that recognizes and phosphorylates Max protein. Proc Natl Acad Sci U S A (1995) 1.37
Human RNA polymerase II subunit hsRPB7 functions in yeast and influences stress survival and cell morphology. Mol Biol Cell (1995) 1.32
Isolation of Drosophila cyclin D, a protein expressed in the morphogenetic furrow before entry into S phase. Proc Natl Acad Sci U S A (1996) 1.30
Mlx, a new Max-like bHLHZip family member: the center stage of a novel transcription factors regulatory pathway? Oncogene (2000) 1.26
Rox, a novel bHLHZip protein expressed in quiescent cells that heterodimerizes with Max, binds a non-canonical E box and acts as a transcriptional repressor. EMBO J (1997) 1.25
roughex down-regulates G2 cyclins in G1. Genes Dev (1997) 1.19
"Mutagenesis" by peptide aptamers identifies genetic network members and pathway connections. Proc Natl Acad Sci U S A (1999) 1.18
Specific DNA recognition and intersite spacing are critical for action of the bicoid morphogen. Mol Cell Biol (1994) 1.17
DNA binding is not sufficient for nuclear localization of regulatory proteins in Saccharomyces cerevisiae. Mol Cell Biol (1986) 1.15
An artificial cell-cycle inhibitor isolated from a combinatorial library. Proc Natl Acad Sci U S A (1998) 1.15
p16 proteins from melanoma-prone families are deficient in binding to Cdk4. Oncogene (1995) 1.14
A yeast transcription assay defines distinct rel and dorsal DNA recognition sequences. New Biol (1991) 1.12
Applications of interaction traps/two-hybrid systems to biotechnology research. Curr Opin Biotechnol (1994) 1.05
The impact of two-hybrid and related methods on biotechnology. Trends Biotechnol (1998) 1.02
Inhibition of mammalian cell proliferation by genetically selected peptide aptamers that functionally antagonize E2F activity. Oncogene (1999) 1.00
Cells that register logical relationships among proteins. Proc Natl Acad Sci U S A (1997) 0.99
Regulation and autoregulation by lexA protein. Biochimie (1983) 0.98
Dimerization of the human papillomavirus E7 oncoprotein in vivo. Virology (1995) 0.96
LCK-phosphorylated human killer cell-inhibitory receptors recruit and activate phosphatidylinositol 3-kinase. Proc Natl Acad Sci U S A (1998) 0.95
Assessing borderline personality disorder with self-report, clinical interview, or semistructured interview. Am J Psychiatry (1984) 0.92
Selection of genetic agents from random peptide aptamer expression libraries. Methods Enzymol (2000) 0.91
The ankyrin repeat-containing adaptor protein Tvl-1 is a novel substrate and regulator of Raf-1. J Biol Chem (1999) 0.91
Targeted localized degradation of Paired protein in Drosophila development. Curr Biol (2000) 0.89
Targeted modification and transportation of cellular proteins. Proc Natl Acad Sci U S A (2000) 0.86
Large-scale preparation of plasmid DNA. Curr Protoc Mol Biol (2001) 0.86
Murine chromosomal location of five bHLH-Zip transcription factor genes. Genomics (1995) 0.82
Mxi1, a protein that specifically interacts with Max to bind Myc-Max recognition sites. Cell (1994) 0.82
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Plating lambda phage to generate plaques. Curr Protoc Mol Biol (2001) 0.77
Media preparation and bacteriological tools. Curr Protoc Protein Sci (2001) 0.77
Ventilatory and circulatory changes during cold exposure in the Pekin duck Anas platyrhynchos. Respir Physiol (1984) 0.77
Looms to weave genomic nets. Nat Genet (1997) 0.77
Growth in liquid or solid media. Curr Protoc Protein Sci (2001) 0.76
Interaction trap/two-hybrid system to identify interacting proteins. Curr Protoc Cell Biol (2001) 0.76
Inhibition of X-ray-induced exencephaly by protease inhibitors. Radiat Res (1990) 0.76
Interaction trap/two-hybrid system to identify interacting proteins. Curr Protoc Protein Sci (2001) 0.76
Backward bicoid? Structure (1994) 0.75
Double-stranded DNA arrays: next steps in the surface campaign. Nat Biotechnol (1999) 0.75
Introduction to lambda phages. Curr Protoc Mol Biol (2001) 0.75
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Preparation of plasmid DNA. Curr Protoc Protein Sci (2001) 0.75
Fluphenazine resistant psychosis. Can J Psychiatry (1981) 0.75
Postgenomic protein analysis: the next bend in the river. Nat Biotechnol (1998) 0.75
Growing bacteria on solid media. Curr Protoc Cytom (2001) 0.75
Preparation of bacterial plasmid DNA. Curr Protoc Immunol (2001) 0.75
Lambda as a cloning vector. Curr Protoc Mol Biol (2001) 0.75
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Getting doctors to underserviced areas. Can Doct (1982) 0.75
Growing bacteria in liquid media. Curr Protoc Cytom (2001) 0.75
Interaction trap/two-hybrid system to identify interacting proteins. Curr Protoc Neurosci (2001) 0.75
Preparation of bacterial plasmid DNA. Curr Protoc Neurosci (2001) 0.75