Published in J Neurosci on February 01, 2003
Monocyte chemoattractant protein-1 (MCP-1): an overview. J Interferon Cytokine Res (2009) 7.83
MAP kinase and pain. Brain Res Rev (2008) 3.75
p38 MAPK, microglial signaling, and neuropathic pain. Mol Pain (2007) 2.72
Non-stereoselective reversal of neuropathic pain by naloxone and naltrexone: involvement of toll-like receptor 4 (TLR4). Eur J Neurosci (2008) 2.65
Chemokines, neuronal-glial interactions, and central processing of neuropathic pain. Pharmacol Ther (2010) 2.27
Glia and pain: is chronic pain a gliopathy? Pain (2013) 2.21
Cytokines, inflammation, and pain. Int Anesthesiol Clin (2007) 2.01
Proinflammatory cytokines oppose opioid-induced acute and chronic analgesia. Brain Behav Immun (2008) 1.92
Role of the CX3CR1/p38 MAPK pathway in spinal microglia for the development of neuropathic pain following nerve injury-induced cleavage of fractalkine. Brain Behav Immun (2006) 1.88
Targeting astrocyte signaling for chronic pain. Neurotherapeutics (2010) 1.88
Capnellene, a natural marine compound derived from soft coral, attenuates chronic constriction injury-induced neuropathic pain in rats. Br J Pharmacol (2009) 1.82
Robust increase of cutaneous sensitivity, cytokine production and sympathetic sprouting in rats with localized inflammatory irritation of the spinal ganglia. Neuroscience (2006) 1.78
Intrathecal interleukin-10 gene therapy attenuates paclitaxel-induced mechanical allodynia and proinflammatory cytokine expression in dorsal root ganglia in rats. Brain Behav Immun (2006) 1.67
Long-term potentiation in spinal nociceptive pathways as a novel target for pain therapy. Mol Pain (2011) 1.66
Controlling neuropathic pain by adeno-associated virus driven production of the anti-inflammatory cytokine, interleukin-10. Mol Pain (2005) 1.66
Exploring the neuroimmunopharmacology of opioids: an integrative review of mechanisms of central immune signaling and their implications for opioid analgesia. Pharmacol Rev (2011) 1.66
Chronic Pain, Psychopathology, and DSM-5 Somatic Symptom Disorder. Can J Psychiatry (2015) 1.46
The effects of thalidomide and minocycline on taxol-induced hyperalgesia in rats. Brain Res (2008) 1.45
Pain-related sensory innervation in monoiodoacetate-induced osteoarthritis in rat knees that gradually develops neuronal injury in addition to inflammatory pain. BMC Musculoskelet Disord (2011) 1.45
Possible role of spinal astrocytes in maintaining chronic pain sensitization: review of current evidence with focus on bFGF/JNK pathway. Neuron Glia Biol (2006) 1.41
Glia in pathological pain: a role for fractalkine. J Neuroimmunol (2008) 1.39
Spinal microglial and perivascular cell cannabinoid receptor type 2 activation reduces behavioral hypersensitivity without tolerance after peripheral nerve injury. Anesthesiology (2008) 1.39
Transplanted astrocytes derived from BMP- or CNTF-treated glial-restricted precursors have opposite effects on recovery and allodynia after spinal cord injury. J Biol (2008) 1.36
Do glial cells control pain? Neuron Glia Biol (2007) 1.30
Propentofylline attenuates allodynia, glial activation and modulates GABAergic tone after spinal cord injury in the rat. Pain (2008) 1.29
Protection against oxaliplatin-induced mechanical hyperalgesia and intraepidermal nerve fiber loss by minocycline. Exp Neurol (2011) 1.27
Characterization of rodent models of HIV-gp120 and anti-retroviral-associated neuropathic pain. Brain (2007) 1.25
Pharmacological, behavioural and mechanistic analysis of HIV-1 gp120 induced painful neuropathy. Pain (2007) 1.21
Gliopathy ensures persistent inflammation and chronic pain after spinal cord injury. Exp Neurol (2008) 1.21
Astroglia in medullary dorsal horn (trigeminal spinal subnucleus caudalis) are involved in trigeminal neuropathic pain mechanisms. J Neurosci (2009) 1.20
Intrathecal polymer-based interleukin-10 gene delivery for neuropathic pain. Neuron Glia Biol (2006) 1.18
Microglia and spinal cord synaptic plasticity in persistent pain. Neural Plast (2013) 1.17
Increase in inflammatory cytokines in median nerves in a rat model of repetitive motion injury. J Neuroimmunol (2005) 1.17
Spinal astrocyte gap junctions contribute to oxaliplatin-induced mechanical hypersensitivity. J Pain (2013) 1.16
The role of enhanced cutaneous IL-1beta signaling in a rat tibia fracture model of complex regional pain syndrome. Pain (2009) 1.15
Chronic-pain-associated astrocytic reaction in the spinal cord dorsal horn of human immunodeficiency virus-infected patients. J Neurosci (2012) 1.15
Gene transfer of GLT-1, a glial glutamate transporter, into the spinal cord by recombinant adenovirus attenuates inflammatory and neuropathic pain in rats. Mol Pain (2008) 1.14
Targeting chemokine (C-C motif) ligand 2 (CCL2) as an example of translation of cancer molecular biology to the clinic. Prog Mol Biol Transl Sci (2010) 1.14
Bilateral changes of TNF-alpha and IL-10 protein in the lumbar and cervical dorsal root ganglia following a unilateral chronic constriction injury of the sciatic nerve. J Neuroinflammation (2010) 1.14
Chemokine contribution to neuropathic pain: respective induction of CXCL1 and CXCR2 in spinal cord astrocytes and neurons. Pain (2013) 1.10
Dissociation of spinal microglia morphological activation and peripheral inflammation in inflammatory pain models. J Neuroimmunol (2007) 1.10
Chronic neuropathic pain-like behavior correlates with IL-1β expression and disrupts cytokine interactions in the hippocampus. Pain (2011) 1.09
Spinal injection of TNF-α-activated astrocytes produces persistent pain symptom mechanical allodynia by releasing monocyte chemoattractant protein-1. Glia (2010) 1.09
Leak K⁺ channel mRNAs in dorsal root ganglia: relation to inflammation and spontaneous pain behaviour. Mol Cell Neurosci (2012) 1.08
Inhibition of Kinesin-5, a microtubule-based motor protein, as a strategy for enhancing regeneration of adult axons. Traffic (2011) 1.07
Role of spinal microglia in visceral hyperalgesia and NK1R up-regulation in a rat model of chronic stress. Gastroenterology (2008) 1.07
Anti-inflammatory cytokine gene therapy decreases sensory and motor dysfunction in experimental Multiple Sclerosis: MOG-EAE behavioral and anatomical symptom treatment with cytokine gene therapy. Brain Behav Immun (2008) 1.05
Calcitonin gene-related peptide promotes cellular changes in trigeminal neurons and glia implicated in peripheral and central sensitization. Mol Pain (2011) 1.04
Interleukin-6 mediates low-threshold mechanical allodynia induced by intrathecal HIV-1 envelope glycoprotein gp120. Brain Behav Immun (2007) 1.02
Inhibition of spinal astrocytic c-Jun N-terminal kinase (JNK) activation correlates with the analgesic effects of ketamine in neuropathic pain. J Neuroinflammation (2011) 1.02
Role of spinal cord glia in the central processing of peripheral pain perception. Neurogastroenterol Motil (2010) 1.01
Minocycline blocks lipopolysaccharide induced hyperalgesia by suppression of microglia but not astrocytes. Neuroscience (2012) 1.01
Light touch induces ERK activation in superficial dorsal horn neurons after inflammation: involvement of spinal astrocytes and JNK signaling in touch-evoked central sensitization and mechanical allodynia. J Neurochem (2010) 1.00
Gabapentin reduces CX3CL1 signaling and blocks spinal microglial activation in monoarthritic rats. Mol Brain (2012) 0.99
A shed form of LDL receptor-related protein-1 regulates peripheral nerve injury and neuropathic pain in rodents. J Clin Invest (2008) 0.99
Matrix metalloprotease regulation of neuropathic pain. Trends Pharmacol Sci (2009) 0.99
Robust spinal neuroinflammation mediates mechanical allodynia in Walker 256 induced bone cancer rats. Mol Brain (2012) 0.99
Key role for spinal dorsal horn microglial kinin B1 receptor in early diabetic pain neuropathy. J Neuroinflammation (2010) 0.98
Intervention of electroacupuncture on spinal p38 MAPK/ATF-2/VR-1 pathway in treating inflammatory pain induced by CFA in rats. Mol Pain (2013) 0.98
Spreading of complex regional pain syndrome: not a random process. J Neural Transm (Vienna) (2011) 0.97
Activation of spinal microglia in a murine model of peripheral inflammation-induced, long-lasting contralateral allodynia. Neurosci Lett (2008) 0.97
TRAF6 upregulation in spinal astrocytes maintains neuropathic pain by integrating TNF-α and IL-1β signaling. Pain (2014) 0.95
Regulation of the trigeminal NR1 subunit expression induced by inflammation of the temporomandibular joint region in rats. Pain (2008) 0.94
Distinctive response of CNS glial cells in oro-facial pain associated with injury, infection and inflammation. Mol Pain (2010) 0.93
Immunological priming potentiates non-viral anti-inflammatory gene therapy treatment of neuropathic pain. Gene Ther (2009) 0.93
Neuroinflammation and comorbidity of pain and depression. Pharmacol Rev (2013) 0.93
The transition from acute to chronic pain: might intensive care unit patients be at risk? Ann Intensive Care (2012) 0.92
Clonidine reduces hypersensitivity and alters the balance of pro- and anti-inflammatory leukocytes after local injection at the site of inflammatory neuritis. Brain Behav Immun (2006) 0.92
Is BDNF sufficient for information transfer between microglia and dorsal horn neurons during the onset of central sensitization? Mol Pain (2010) 0.92
Chronic neuropathic pain-like behavior and brain-borne IL-1β. Ann N Y Acad Sci (2012) 0.90
Is functional state of spinal microglia involved in the anti-allodynic and anti-hyperalgesic effects of electroacupuncture in rat model of monoarthritis? Neurobiol Dis (2007) 0.90
Spinal interleukin-17 promotes thermal hyperalgesia and NMDA NR1 phosphorylation in an inflammatory pain rat model. Pain (2012) 0.90
Behavioral evidence for the differential regulation of p-p38 MAPK and p-NF-κB in rats with trigeminal neuropathic pain. Mol Pain (2011) 0.90
Regulation of Wnt signaling by nociceptive input in animal models. Mol Pain (2012) 0.90
Pain in experimental autoimmune encephalitis: a comparative study between different mouse models. J Neuroinflammation (2012) 0.89
Analgesic effect of acupuncture is mediated via inhibition of JNK activation in astrocytes after spinal cord injury. PLoS One (2013) 0.88
Long-term actions of interleukin-1beta on delay and tonic firing neurons in rat superficial dorsal horn and their relevance to central sensitization. Mol Pain (2008) 0.88
siRNA-mediated knockdown of the NR1 subunit gene of the NMDA receptor attenuates formalin-induced pain behaviors in adult rats. J Pain (2009) 0.88
Extracellular high-mobility group box 1 protein (HMGB1) as a mediator of persistent pain. Mol Med (2015) 0.88
Below level central pain induced by discrete dorsal spinal cord injury. J Neurotrauma (2010) 0.87
Role of spinal P2Y6 and P2Y11 receptors in neuropathic pain in rats: possible involvement of glial cells. Mol Pain (2014) 0.86
Spinal toll-like receptor signaling and nociceptive processing: regulatory balance between TIRAP and TRIF cascades mediated by TNF and IFNβ. Pain (2013) 0.86
Dietary grape seed polyphenols repress neuron and glia activation in trigeminal ganglion and trigeminal nucleus caudalis. Mol Pain (2010) 0.85
Long-term control of neuropathic pain in a non-viral gene therapy paradigm. Gene Ther (2009) 0.85
Characterization of NF-kB-mediated inhibition of catechol-O-methyltransferase. Mol Pain (2009) 0.85
Ketamine as an adjuvant in sympathetic blocks for management of central sensitization following peripheral nerve injury. J Brachial Plex Peripher Nerve Inj (2008) 0.84
The Inhibition of Spinal Astrocytic JAK2-STAT3 Pathway Activation Correlates with the Analgesic Effects of Triptolide in the Rat Neuropathic Pain Model. Evid Based Complement Alternat Med (2012) 0.84
Bilateral sensory abnormalities in patients with unilateral neuropathic pain; a quantitative sensory testing (QST) study. PLoS One (2012) 0.84
P2 receptors and chronic pain. Purinergic Signal (2007) 0.83
Central nociceptive sensitization vs. spinal cord training: opposing forms of plasticity that dictate function after complete spinal cord injury. Front Physiol (2012) 0.83
Cerebral biochemical pathways in experimental autoimmune encephalomyelitis and adjuvant arthritis: a comparative metabolomic study. PLoS One (2013) 0.83
Cell cycle inhibition limits development and maintenance of neuropathic pain following spinal cord injury. Pain (2016) 0.82
Combining ketamine with astrocytic inhibitor as a potential analgesic strategy for neuropathic pain ketamine, astrocytic inhibitor and pain. Mol Pain (2010) 0.82
Toll-like receptor 2 contributes to chemokine gene expression and macrophage infiltration in the dorsal root ganglia after peripheral nerve injury. Mol Pain (2011) 0.82
Increase in hemokinin-1 mRNA in the spinal cord during the early phase of a neuropathic pain state. Br J Pharmacol (2008) 0.82
Role of lipocalin-2-chemokine axis in the development of neuropathic pain following peripheral nerve injury. J Biol Chem (2013) 0.82
Spinal glia modulate both adaptive and pathological processes. Brain Behav Immun (2009) 0.82
The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression. Genome Res (2012) 15.41
Pathological and protective roles of glia in chronic pain. Nat Rev Neurosci (2009) 5.53
Functional classification of proteins for the prediction of cellular function from a protein-protein interaction network. Genome Biol (2003) 3.80
Advances in neuropathic pain: diagnosis, mechanisms, and treatment recommendations. Arch Neurol (2003) 3.80
Mutation detection using Surveyor nuclease. Biotechniques (2004) 3.72
Minocycline attenuates mechanical allodynia and proinflammatory cytokine expression in rat models of pain facilitation. Pain (2005) 3.34
Stressor controllability and learned helplessness: the roles of the dorsal raphe nucleus, serotonin, and corticotropin-releasing factor. Neurosci Biobehav Rev (2005) 3.25
To restimulate or not in dose titration. J ECT (2007) 3.23
The "toll" of opioid-induced glial activation: improving the clinical efficacy of opioids by targeting glia. Trends Pharmacol Sci (2009) 3.06
Continuation electroconvulsive therapy vs pharmacotherapy for relapse prevention in major depression: a multisite study from the Consortium for Research in Electroconvulsive Therapy (CORE). Arch Gen Psychiatry (2006) 2.93
Microglia serve as a neuroimmune substrate for stress-induced potentiation of CNS pro-inflammatory cytokine responses. Brain Behav Immun (2006) 2.89
Beyond neurons: evidence that immune and glial cells contribute to pathological pain states. Physiol Rev (2002) 2.75
Glia: a novel drug discovery target for clinical pain. Nat Rev Drug Discov (2003) 2.71
Defects in nuclear structure and function promote dilated cardiomyopathy in lamin A/C-deficient mice. J Clin Invest (2004) 2.67
Evaluation of annotation strategies using an entire genome sequence. Bioinformatics (2003) 2.66
Non-stereoselective reversal of neuropathic pain by naloxone and naltrexone: involvement of toll-like receptor 4 (TLR4). Eur J Neurosci (2008) 2.65
Context-based tourism information filtering with a semantic rule engine. Sensors (Basel) (2012) 2.51
Opioid-induced glial activation: mechanisms of activation and implications for opioid analgesia, dependence, and reward. ScientificWorldJournal (2007) 2.43
Intussusception risk after rotavirus vaccination in U.S. infants. N Engl J Med (2014) 2.41
Peripheral infection and aging interact to impair hippocampal memory consolidation. Neurobiol Aging (2006) 2.37
"Brain-specific" nutrients: a memory cure? Nutrition (2003) 2.29
Infusion of pharmaceutical-grade natural human C-reactive protein is not proinflammatory in healthy adult human volunteers. Circ Res (2013) 2.26
Calcification is associated with loss of functional calcium-sensing receptor in vascular smooth muscle cells. Cardiovasc Res (2008) 2.23
Penile length alterations following penile prosthesis surgery. Eur Urol (2006) 2.20
Evidence that opioids may have toll-like receptor 4 and MD-2 effects. Brain Behav Immun (2009) 2.19
A role for proinflammatory cytokines and fractalkine in analgesia, tolerance, and subsequent pain facilitation induced by chronic intrathecal morphine. J Neurosci (2004) 2.14
Overall quality of outcomes framework scores lower in practices in deprived areas. Br J Gen Pract (2006) 2.14
Hypernociceptive role of cytokines and chemokines: targets for analgesic drug development? Pharmacol Ther (2006) 2.13
Fractalkine (CX3CL1) and fractalkine receptor (CX3CR1) distribution in spinal cord and dorsal root ganglia under basal and neuropathic pain conditions. Eur J Neurosci (2004) 2.11
"Cytokine storm" in the phase I trial of monoclonal antibody TGN1412: better understanding the causes to improve preclinical testing of immunotherapeutics. J Immunol (2007) 2.11
Evolutionary breakpoints in the gibbon suggest association between cytosine methylation and karyotype evolution. PLoS Genet (2009) 2.07
Previous experience with behavioral control over stress blocks the behavioral and dorsal raphe nucleus activating effects of later uncontrollable stress: role of the ventral medial prefrontal cortex. J Neurosci (2006) 2.07
mRNA up-regulation of MHC II and pivotal pro-inflammatory genes in normal brain aging. Neurobiol Aging (2006) 2.06
Norman Cousins Lecture. Glia as the "bad guys": implications for improving clinical pain control and the clinical utility of opioids. Brain Behav Immun (2006) 2.00
Seizure threshold in a large sample: implications for stimulus dosing strategies in bilateral electroconvulsive therapy: a report from CORE. J ECT (2009) 1.99
Low rates of testing and diagnostic codes usage in a commercial clinical laboratory: evidence for lack of physician awareness of chronic kidney disease. J Am Soc Nephrol (2005) 1.98
Ablation for longstanding permanent atrial fibrillation: results from a randomized study comparing three different strategies. Heart Rhythm (2008) 1.96
MLH1 germline epimutations as a factor in hereditary nonpolyposis colorectal cancer. Gastroenterology (2005) 1.94
Intracisternal interleukin-1 receptor antagonist prevents postoperative cognitive decline and neuroinflammatory response in aged rats. J Neurosci (2012) 1.93
Proinflammatory cytokines oppose opioid-induced acute and chronic analgesia. Brain Behav Immun (2008) 1.92
Freewheel running prevents learned helplessness/behavioral depression: role of dorsal raphe serotonergic neurons. J Neurosci (2003) 1.91
Distance, rurality and the need for care: access to health services in South West England. Int J Health Geogr (2004) 1.90
Glia: novel counter-regulators of opioid analgesia. Trends Neurosci (2005) 1.86
Glial proinflammatory cytokines mediate exaggerated pain states: implications for clinical pain. Adv Exp Med Biol (2003) 1.84
Time course of hippocampal IL-1 beta and memory consolidation impairments in aging rats following peripheral infection. Brain Behav Immun (2008) 1.82
Prior stressor exposure sensitizes LPS-induced cytokine production. Brain Behav Immun (2002) 1.82
Morphine activates neuroinflammation in a manner parallel to endotoxin. Proc Natl Acad Sci U S A (2012) 1.80
Glial activation and pathological pain. Neurochem Int (2004) 1.80
1,25-Dihydroxyvitamin D3 but not cinacalcet HCl (Sensipar/Mimpara) treatment mediates aortic calcification in a rat model of secondary hyperparathyroidism. Nephrol Dial Transplant (2005) 1.76
SPOTS: signaling protein oligomeric transduction structures are early mediators of death receptor-induced apoptosis at the plasma membrane. J Cell Biol (2004) 1.75
The histone variant macroH2A is an epigenetic regulator of key developmental genes. Nat Struct Mol Biol (2009) 1.75
Controlling pathological pain by adenovirally driven spinal production of the anti-inflammatory cytokine, interleukin-10. Eur J Neurosci (2005) 1.73
Molecular biology of mosquito vitellogenesis: from basic studies to genetic engineering of antipathogen immunity. Insect Biochem Mol Biol (2002) 1.72
Genome-wide identification of in vivo Drosophila Engrailed-binding DNA fragments and related target genes. Development (2003) 1.70
Toll-like receptor 4 in CNS pathologies. J Neurochem (2010) 1.68
Electrical isolation of the superior vena cava: an adjunctive strategy to pulmonary vein antrum isolation improving the outcome of AF ablation. J Cardiovasc Electrophysiol (2007) 1.68
Intrathecal interleukin-10 gene therapy attenuates paclitaxel-induced mechanical allodynia and proinflammatory cytokine expression in dorsal root ganglia in rats. Brain Behav Immun (2006) 1.67
Controlling neuropathic pain by adeno-associated virus driven production of the anti-inflammatory cytokine, interleukin-10. Mol Pain (2005) 1.66
Immune globulins and thrombotic adverse events as recorded in a large administrative database in 2008 through 2010. Transfusion (2012) 1.66
Exploring the neuroimmunopharmacology of opioids: an integrative review of mechanisms of central immune signaling and their implications for opioid analgesia. Pharmacol Rev (2011) 1.66
Repeated intrathecal injections of plasmid DNA encoding interleukin-10 produce prolonged reversal of neuropathic pain. Pain (2006) 1.66
Crucial role of neutrophils in the development of mechanical inflammatory hypernociception. J Leukoc Biol (2008) 1.64
A phase III equivalence trial of azithromycin versus benzathine penicillin for treatment of early syphilis. J Infect Dis (2010) 1.64
Pharmacodynamics of the type II calcimimetic compound cinacalcet HCl. J Pharmacol Exp Ther (2003) 1.63
Can calcimimetics inhibit parathyroid hyperplasia? Evidence from preclinical studies. Nephrol Dial Transplant (2007) 1.63
"Listening" and "talking" to neurons: implications of immune activation for pain control and increasing the efficacy of opioids. Brain Res Rev (2007) 1.62
Rapid isolation of highly enriched and quiescent microglia from adult rat hippocampus: immunophenotypic and functional characteristics. J Neurosci Methods (2005) 1.61
Cardiopulmonary resuscitation feedback improves the quality of chest compression provided by hospital health care professionals. Am J Emerg Med (2010) 1.58
Reduction of opioid withdrawal and potentiation of acute opioid analgesia by systemic AV411 (ibudilast). Brain Behav Immun (2008) 1.58
Memory for context is impaired by a post context exposure injection of interleukin-1 beta into dorsal hippocampus. Behav Brain Res (2002) 1.58
Calcimimetic inhibits late-stage cyst growth in ADPKD. J Am Soc Nephrol (2009) 1.58