Published in J Virol on June 01, 2006
HIV-1 Vif, APOBEC, and intrinsic immunity. Retrovirology (2008) 3.72
Defining APOBEC3 expression patterns in human tissues and hematopoietic cell subsets. J Virol (2009) 2.95
Identification of two distinct human immunodeficiency virus type 1 Vif determinants critical for interactions with human APOBEC3G and APOBEC3F. J Virol (2007) 2.64
APOBEC proteins and intrinsic resistance to HIV-1 infection. Philos Trans R Soc Lond B Biol Sci (2009) 2.40
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Identification of amino acid residues in APOBEC3G required for regulation by human immunodeficiency virus type 1 Vif and Virion encapsidation. J Virol (2007) 2.17
DDB1 and Cul4A are required for human immunodeficiency virus type 1 Vpr-induced G2 arrest. J Virol (2007) 1.77
Generation of HIV-1 derivatives that productively infect macaque monkey lymphoid cells. Proc Natl Acad Sci U S A (2006) 1.63
Antiretroviral activity and Vif sensitivity of rhesus macaque APOBEC3 proteins. J Virol (2007) 1.56
Identification of an APOBEC3G binding site in human immunodeficiency virus type 1 Vif and inhibitors of Vif-APOBEC3G binding. J Virol (2007) 1.51
Multiple APOBEC3 restriction factors for HIV-1 and one Vif to rule them all. J Mol Biol (2013) 1.39
Sole copy of Z2-type human cytidine deaminase APOBEC3H has inhibitory activity against retrotransposons and HIV-1. FASEB J (2008) 1.39
A single amino acid difference in human APOBEC3H variants determines HIV-1 Vif sensitivity. J Virol (2009) 1.38
Regulation of APOBEC3 proteins by a novel YXXL motif in human immunodeficiency virus type 1 Vif and simian immunodeficiency virus SIVagm Vif. J Virol (2008) 1.37
The APOBEC3C crystal structure and the interface for HIV-1 Vif binding. Nat Struct Mol Biol (2012) 1.36
A patch of positively charged amino acids surrounding the human immunodeficiency virus type 1 Vif SLVx4Yx9Y motif influences its interaction with APOBEC3G. J Virol (2009) 1.36
The activity spectrum of Vif from multiple HIV-1 subtypes against APOBEC3G, APOBEC3F, and APOBEC3H. J Virol (2011) 1.26
Multiple ways of targeting APOBEC3-virion infectivity factor interactions for anti-HIV-1 drug development. Trends Pharmacol Sci (2009) 1.24
APOBEC3G subunits self-associate via the C-terminal deaminase domain. J Biol Chem (2008) 1.24
Distinct determinants in HIV-1 Vif and human APOBEC3 proteins are required for the suppression of diverse host anti-viral proteins. PLoS One (2008) 1.23
Characterization of the interaction of full-length HIV-1 Vif protein with its key regulator CBFβ and CRL5 E3 ubiquitin ligase components. PLoS One (2012) 1.12
Identification of 81LGxGxxIxW89 and 171EDRW174 domains from human immunodeficiency virus type 1 Vif that regulate APOBEC3G and APOBEC3F neutralizing activity. J Virol (2010) 1.09
HIV-1 Vif-mediated ubiquitination/degradation of APOBEC3G involves four critical lysine residues in its C-terminal domain. Proc Natl Acad Sci U S A (2009) 1.06
Host restriction factors in retroviral infection: promises in virus-host interaction. Retrovirology (2012) 1.05
HIV-1 Vif versus the APOBEC3 cytidine deaminases: an intracellular duel between pathogen and host restriction factors. Mol Aspects Med (2010) 1.03
Advances in the structural understanding of Vif proteins. Curr HIV Res (2008) 1.03
APOBEC3G: an intracellular centurion. Philos Trans R Soc Lond B Biol Sci (2009) 1.02
Structural Features of Antiviral APOBEC3 Proteins are Linked to Their Functional Activities. Front Microbiol (2011) 1.02
Small-molecule inhibition of human immunodeficiency virus type 1 replication by targeting the interaction between Vif and ElonginC. J Virol (2012) 1.01
Identification of dominant negative human immunodeficiency virus type 1 Vif mutants that interfere with the functional inactivation of APOBEC3G by virus-encoded Vif. J Virol (2010) 1.00
Natural polymorphisms in human APOBEC3H and HIV-1 Vif combine in primary T lymphocytes to affect viral G-to-A mutation levels and infectivity. PLoS Genet (2014) 1.00
Productive replication of Vif-chimeric HIV-1 in feline cells. J Virol (2010) 0.99
Distinct viral determinants for the packaging of human cytidine deaminases APOBEC3G and APOBEC3C. Virology (2008) 0.99
Definition of the interacting interfaces of Apobec3G and HIV-1 Vif using MAPPIT mutagenesis analysis. Nucleic Acids Res (2009) 0.98
APOBEC3G polymorphism as a selective barrier to cross-species transmission and emergence of pathogenic SIV and AIDS in a primate host. PLoS Pathog (2013) 0.98
Conserved and non-conserved features of HIV-1 and SIVagm Vif mediated suppression of APOBEC3 cytidine deaminases. Cell Microbiol (2008) 0.97
APOBEC3G: a double agent in defense. Trends Biochem Sci (2011) 0.96
Posttranslational acetylation of the human immunodeficiency virus type 1 integrase carboxyl-terminal domain is dispensable for viral replication. J Virol (2006) 0.93
Insights into cellular factors that regulate HIV-1 replication in human cells. Biochemistry (2011) 0.92
Differential virus restriction patterns of rhesus macaque and human APOBEC3A: implications for lentivirus evolution. Virology (2011) 0.92
Structural Insights into HIV-1 Vif-APOBEC3F Interaction. J Virol (2015) 0.91
N-terminal hemagglutinin tag renders lysine-deficient APOBEC3G resistant to HIV-1 Vif-induced degradation by reduced polyubiquitination. J Virol (2011) 0.91
Adaptation of HIV-1 to cells expressing rhesus monkey TRIM5α. Virology (2010) 0.91
Identification of the HIV-1 Vif and Human APOBEC3G Protein Interface. Cell Rep (2015) 0.86
Mucosal and peripheral Lin- HLA-DR+ CD11c/123- CD13+ CD14- mononuclear cells are preferentially infected during acute simian immunodeficiency virus infection. J Virol (2011) 0.86
Dispersed and conserved hydrophobic residues of HIV-1 Vif are essential for CBFβ recruitment and A3G suppression. J Virol (2013) 0.85
The Binding Interface between Human APOBEC3F and HIV-1 Vif Elucidated by Genetic and Computational Approaches. Cell Rep (2015) 0.85
Characterization of anti-HIV activity mediated by R88-APOBEC3G mutant fusion proteins in CD4+ T cells, peripheral blood mononuclear cells, and macrophages. Hum Gene Ther (2011) 0.82
Analysis of Vif-induced APOBEC3G degradation using an alpha-complementation assay. Virology (2006) 0.81
Hydrodynamic and functional analysis of HIV-1 Vif oligomerization. Biochemistry (2012) 0.81
Identification of a novel HIV-1 inhibitor targeting Vif-dependent degradation of human APOBEC3G protein. J Biol Chem (2015) 0.81
Insights into the dual activity of SIVmac239 Vif against human and African green monkey APOBEC3G. PLoS One (2012) 0.80
Catalytic activity of APOBEC3F is required for efficient restriction of Vif-deficient human immunodeficiency virus. Virology (2013) 0.80
Breaking Barriers to an AIDS Model with Macaque-Tropic HIV-1 Derivatives. Biology (Basel) (2012) 0.80
Macaque-tropic human immunodeficiency virus type 1: breaking out of the host restriction factors. Front Microbiol (2013) 0.79
Characterization of RNA binding and chaperoning activities of HIV-1 Vif protein. Importance of the C-terminal unstructured tail. RNA Biol (2014) 0.78
HIV-1 Adapts To Replicate in Cells Expressing Common Marmoset APOBEC3G and BST2. J Virol (2015) 0.76
Structural analysis of viral infectivity factor of HIV type 1 and its interaction with A3G, EloC and EloB. PLoS One (2014) 0.76
Towards Inhibition of Vif-APOBEC3G Interaction: Which Protein to Target? Adv Virol (2010) 0.75
Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein. Nature (2002) 21.53
The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys. Nature (2004) 17.56
Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts. Nature (2003) 13.24
DNA deamination mediates innate immunity to retroviral infection. Cell (2003) 12.10
Induction of APOBEC3G ubiquitination and degradation by an HIV-1 Vif-Cul5-SCF complex. Science (2003) 10.79
The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA. Nature (2003) 10.76
Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif. Cell (2003) 9.48
Cytidine deamination of retroviral DNA by diverse APOBEC proteins. Curr Biol (2004) 6.51
Single-strand specificity of APOBEC3G accounts for minus-strand deamination of the HIV genome. Nat Struct Mol Biol (2004) 6.26
A second human antiretroviral factor, APOBEC3F, is suppressed by the HIV-1 and HIV-2 Vif proteins. EMBO J (2004) 5.67
Vif overcomes the innate antiviral activity of APOBEC3G by promoting its degradation in the ubiquitin-proteasome pathway. J Biol Chem (2003) 5.45
Human APOBEC3F is another host factor that blocks human immunodeficiency virus type 1 replication. J Virol (2004) 5.35
Restriction of lentivirus in monkeys. Proc Natl Acad Sci U S A (2002) 5.02
Retroviral restriction by APOBEC proteins. Nat Rev Immunol (2004) 5.00
APOBEC3F properties and hypermutation preferences indicate activity against HIV-1 in vivo. Curr Biol (2004) 4.89
Species-specific, postentry barriers to primate immunodeficiency virus infection. J Virol (1999) 4.54
A dominant block to HIV-1 replication at reverse transcription in simian cells. Proc Natl Acad Sci U S A (2002) 4.52
Restriction of multiple divergent retroviruses by Lv1 and Ref1. EMBO J (2003) 4.19
A single amino acid of APOBEC3G controls its species-specific interaction with virion infectivity factor (Vif). Proc Natl Acad Sci U S A (2004) 3.73
A single amino acid difference in the host APOBEC3G protein controls the primate species specificity of HIV type 1 virion infectivity factor. Proc Natl Acad Sci U S A (2004) 3.60
Natural variation in Vif: differential impact on APOBEC3G/3F and a potential role in HIV-1 diversification. PLoS Pathog (2005) 3.59
APOBEC3A is a potent inhibitor of adeno-associated virus and retrotransposons. Curr Biol (2006) 3.57
APOBEC3B and APOBEC3C are potent inhibitors of simian immunodeficiency virus replication. J Biol Chem (2004) 3.56
APOBEC3G cytidine deaminase inhibits retrotransposition of endogenous retroviruses. Nature (2005) 3.53
APOBEC3A and APOBEC3B are potent inhibitors of LTR-retrotransposon function in human cells. Nucleic Acids Res (2006) 3.15
A single amino acid substitution in human APOBEC3G antiretroviral enzyme confers resistance to HIV-1 virion infectivity factor-induced depletion. Proc Natl Acad Sci U S A (2004) 2.99
Restriction of HIV-1 (subtype B) replication at the entry step in rhesus macaque cells. Virology (1996) 2.83
A single amino acid determinant governs the species-specific sensitivity of APOBEC3G to Vif action. J Biol Chem (2004) 2.79
Early replication block of human immunodeficiency virus type 1 in monkey cells. J Gen Virol (1995) 2.73
Binding and susceptibility to postentry restriction factors in monkey cells are specified by distinct regions of the human immunodeficiency virus type 1 capsid. J Virol (2004) 2.41
Comparative analysis of the antiretroviral activity of APOBEC3G and APOBEC3F from primates. Virology (2006) 1.94
The innate antiretroviral factor APOBEC3G does not affect human LINE-1 retrotransposition in a cell culture assay. J Biol Chem (2004) 1.36
Understanding the basis of CD4(+) T-cell depletion in macaques infected by a simian-human immunodeficiency virus. Vaccine (2002) 0.87
Human immunodeficiency virus type 1 Vif supports efficient primate lentivirus replication in rhesus monkey cells. J Gen Virol (2003) 0.80
The Sorcerer II Global Ocean Sampling expedition: expanding the universe of protein families. PLoS Biol (2007) 13.99
Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif. Cell (2003) 9.48
The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans. Nature (2008) 6.69
The genome of the sea urchin Strongylocentrotus purpuratus. Science (2006) 6.41
Single-strand specificity of APOBEC3G accounts for minus-strand deamination of the HIV genome. Nat Struct Mol Biol (2004) 6.26
Genomic minimalism in the early diverging intestinal parasite Giardia lamblia. Science (2007) 5.69
Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a model eukaryote. PLoS Biol (2006) 5.44
The Amphimedon queenslandica genome and the evolution of animal complexity. Nature (2010) 5.11
A dominant block to HIV-1 replication at reverse transcription in simian cells. Proc Natl Acad Sci U S A (2002) 4.52
SAMHD1 restricts HIV-1 infection in resting CD4(+) T cells. Nat Med (2012) 4.27
Structural and functional diversity of the microbial kinome. PLoS Biol (2007) 3.74
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APOBEC3A is a potent inhibitor of adeno-associated virus and retrotransposons. Curr Biol (2006) 3.57
APOBEC3B and APOBEC3C are potent inhibitors of simian immunodeficiency virus replication. J Biol Chem (2004) 3.56
Complementary function of the two catalytic domains of APOBEC3G. Virology (2005) 3.45
Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB. Nature (2011) 3.32
The Selaginella genome identifies genetic changes associated with the evolution of vascular plants. Science (2011) 3.10
TORC-specific phosphorylation of mammalian target of rapamycin (mTOR): phospho-Ser2481 is a marker for intact mTOR signaling complex 2. Cancer Res (2009) 2.96
The fold of alpha-synuclein fibrils. Proc Natl Acad Sci U S A (2008) 2.82
Abrogation of postentry restriction of HIV-1-based lentiviral vector transduction in simian cells. Proc Natl Acad Sci U S A (2003) 2.71
Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis. Nat Chem Biol (2009) 2.70
HIV-1 Vpr function is mediated by interaction with the damage-specific DNA-binding protein DDB1. Proc Natl Acad Sci U S A (2007) 2.50
The mouse kinome: discovery and comparative genomics of all mouse protein kinases. Proc Natl Acad Sci U S A (2004) 2.50
Structure of the pseudokinase VRK3 reveals a degraded catalytic site, a highly conserved kinase fold, and a putative regulatory binding site. Structure (2009) 2.33
Insights into evolution of multicellular fungi from the assembled chromosomes of the mushroom Coprinopsis cinerea (Coprinus cinereus). Proc Natl Acad Sci U S A (2010) 2.30
Human immunodeficiency virus type 1 Vpr induces the degradation of the UNG and SMUG uracil-DNA glycosylases. J Virol (2005) 2.17
RPN-6 determines C. elegans longevity under proteotoxic stress conditions. Nature (2012) 2.11
Evidence for an activation domain at the amino terminus of simian immunodeficiency virus Vpx. J Virol (2009) 1.91
Guidelines for naming nonprimate APOBEC3 genes and proteins. J Virol (2008) 1.86
Human immunodeficiency virus type 1 modified to package Simian immunodeficiency virus Vpx efficiently infects macrophages and dendritic cells. J Virol (2011) 1.85
CCR5 is a receptor for Staphylococcus aureus leukotoxin ED. Nature (2012) 1.85
Cyclin-dependent kinases: a family portrait. Nat Cell Biol (2009) 1.80
Association of chemokine-mediated block to HIV entry with coreceptor internalization. J Biol Chem (2002) 1.79
Quantitative exploration of the catalytic landscape separating divergent plant sesquiterpene synthases. Nat Chem Biol (2008) 1.77
The dictyostelium kinome--analysis of the protein kinases from a simple model organism. PLoS Genet (2006) 1.69
Deaminase-independent inhibition of parvoviruses by the APOBEC3A cytidine deaminase. PLoS Pathog (2009) 1.65
Assessment of computational methods for predicting the effects of missense mutations in human cancers. BMC Genomics (2013) 1.64
The F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stress. Mol Cell (2009) 1.64
The Raine syndrome protein FAM20C is a Golgi kinase that phosphorylates bio-mineralization proteins. PLoS One (2012) 1.54
The STE20 kinase HGK is broadly expressed in human tumor cells and can modulate cellular transformation, invasion, and adhesion. Mol Cell Biol (2003) 1.52
Restriction of HIV-1 by APOBEC3G is cytidine deaminase-dependent. Virology (2009) 1.50
The Vpx lentiviral accessory protein targets SAMHD1 for degradation in the nucleus. J Virol (2012) 1.47
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The theta-defensin, retrocyclin, inhibits HIV-1 entry. AIDS Res Hum Retroviruses (2003) 1.40
The Capsaspora genome reveals a complex unicellular prehistory of animals. Nat Commun (2013) 1.39
Members of the NIMA-related kinase family promote disassembly of cilia by multiple mechanisms. Mol Biol Cell (2006) 1.38
From Plk1 to Plk5: functional evolution of polo-like kinases. Cell Cycle (2011) 1.36
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Restriction of diverse retroviruses by SAMHD1. Retrovirology (2013) 1.23
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Alpha-complementation assay for HIV envelope glycoprotein-mediated fusion. Virology (2004) 1.06
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Accessories to the crime: recent advances in HIV accessory protein biology. Curr HIV/AIDS Rep (2009) 0.96
New insights into the role of Vif in HIV-1 replication. AIDS Rev (2004) 0.95
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Inhibition of HIV-1 infection by a CCR5-binding cyclophilin from Toxoplasma gondii. Blood (2003) 0.91
Discovery of a metabolic alternative to the classical mevalonate pathway. Elife (2013) 0.91
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Genomics, evolution, and crystal structure of a new family of bacterial spore kinases. Proteins (2010) 0.81
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