Published in J Biol Chem on June 22, 2006
Physiological significance of a peripheral tissue circadian clock. Proc Natl Acad Sci U S A (2008) 5.94
The meter of metabolism. Cell (2008) 5.71
Intrinsic circadian clock of the mammalian retina: importance for retinal processing of visual information. Cell (2007) 2.94
Circadian rhythms and metabolic syndrome: from experimental genetics to human disease. Circ Res (2010) 2.49
Short communication: ischemia/reperfusion tolerance is time-of-day-dependent: mediation by the cardiomyocyte circadian clock. Circ Res (2009) 2.38
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Mitochondria in heart failure. Cardiovasc Res (2010) 1.75
Myocardial ischemia reperfusion injury: from basic science to clinical bedside. Semin Cardiothorac Vasc Anesth (2012) 1.52
O-GlcNAcylation, novel post-translational modification linking myocardial metabolism and cardiomyocyte circadian clock. J Biol Chem (2011) 1.36
Direct regulation of myocardial triglyceride metabolism by the cardiomyocyte circadian clock. J Biol Chem (2009) 1.24
Advances in understanding the peripheral circadian clocks. FASEB J (2012) 1.13
Circadian clock control of endocrine factors. Nat Rev Endocrinol (2014) 1.10
Evidence suggesting that the cardiomyocyte circadian clock modulates responsiveness of the heart to hypertrophic stimuli in mice. Chronobiol Int (2011) 1.10
Potential role for peripheral circadian clock dyssynchrony in the pathogenesis of cardiovascular dysfunction. Sleep Med (2007) 1.10
Mechanism of the circadian clock in physiology. Am J Physiol Regul Integr Comp Physiol (2013) 1.09
Circadian rhythms of melatonin, cortisol, and clock gene expression during simulated night shift work. Sleep (2007) 1.05
Temporal orchestration of repressive chromatin modifiers by circadian clock Period complexes. Nat Struct Mol Biol (2014) 1.05
The myocardial contractile response to physiological stress improves with high saturated fat feeding in heart failure. Am J Physiol Heart Circ Physiol (2010) 1.01
Regulation of fatty acid metabolism by cell autonomous circadian clocks: time to fatten up on information? J Biol Chem (2011) 1.01
Quantitative analysis of light-phase restricted feeding reveals metabolic dyssynchrony in mice. Int J Obes (Lond) (2012) 1.01
Cardiomyocyte-specific BMAL1 plays critical roles in metabolism, signaling, and maintenance of contractile function of the heart. J Biol Rhythms (2014) 0.99
A mammalian monothiol glutaredoxin, Grx3, is critical for cell cycle progression during embryogenesis. FEBS J (2011) 0.97
Anticipating anticipation: pursuing identification of cardiomyocyte circadian clock function. J Appl Physiol (1985) (2009) 0.96
Rapid attenuation of circadian clock gene oscillations in the rat heart following ischemia-reperfusion. J Mol Cell Cardiol (2007) 0.95
Disruption of rhythms of molecular clocks in primary synovial fibroblasts of patients with osteoarthritis and rheumatoid arthritis, role of IL-1β/TNF. Arthritis Res Ther (2012) 0.93
Cyclic GMP signaling in cardiomyocytes modulates fatty acid trafficking and prevents triglyceride accumulation. J Mol Cell Cardiol (2008) 0.87
Integrating beat rate variability: from single cells to hearts. Heart Rhythm (2013) 0.87
The day/night proteome in the murine heart. Am J Physiol Regul Integr Comp Physiol (2014) 0.87
The circadian clock maintains cardiac function by regulating mitochondrial metabolism in mice. PLoS One (2014) 0.87
Clock genes in hypertension: novel insights from rodent models. Blood Press Monit (2014) 0.86
Circadian rhythms, Wnt/beta-catenin pathway and PPAR alpha/gamma profiles in diseases with primary or secondary cardiac dysfunction. Front Physiol (2014) 0.85
Regulation of myocardial metabolism by the cardiomyocyte circadian clock. J Mol Cell Cardiol (2012) 0.85
Circadian profiles in the embryonic chick heart: L-type voltage-gated calcium channels and signaling pathways. Chronobiol Int (2010) 0.84
Circadian clock and the onset of cardiovascular events. Hypertens Res (2016) 0.84
A Circadian Clock Gene, Cry, Affects Heart Morphogenesis and Function in Drosophila as Revealed by Optical Coherence Microscopy. PLoS One (2015) 0.83
Influence of dark phase restricted high fat feeding on myocardial adaptation in mice. J Mol Cell Cardiol (2012) 0.83
Assessing Cardiac Metabolism: A Scientific Statement From the American Heart Association. Circ Res (2016) 0.82
The circadian protein Clock localizes to the sarcomeric Z-disk and is a sensor of myofilament cross-bridge activity in cardiac myocytes. Biochem Biophys Res Commun (2006) 0.82
Histone monoubiquitination by Clock-Bmal1 complex marks Per1 and Per2 genes for circadian feedback. Nat Struct Mol Biol (2015) 0.81
Metabolic cycles are linked to the cardiovascular diurnal rhythm in rats with essential hypertension. PLoS One (2011) 0.80
Cardiac-specific mutation of Clock alters the quantitative measurements of physical activities without changing behavioral circadian rhythms. J Biol Rhythms (2011) 0.80
Cardiomyocyte-specific Bmal1 deletion in mice triggers diastolic dysfunction, extracellular matrix response, and impaired resolution of inflammation. Am J Physiol Heart Circ Physiol (2015) 0.79
Chronobiology and obesity: Interactions between circadian rhythms and energy regulation. Adv Nutr (2014) 0.79
PPARs, Cardiovascular Metabolism, and Function: Near- or Far-from-Equilibrium Pathways. PPAR Res (2010) 0.78
The end effector of circadian heart rate variation: the sinoatrial node pacemaker cell. BMB Rep (2015) 0.78
Differential contribution of rod and cone circadian clocks in driving retinal melatonin rhythms in Xenopus. PLoS One (2010) 0.77
Altered myocardial metabolic adaptation to increased fatty acid availability in cardiomyocyte-specific CLOCK mutant mice. Biochim Biophys Acta (2015) 0.77
Interrelationship between 3,5,3´-triiodothyronine and the circadian clock in the rodent heart. Chronobiol Int (2016) 0.77
The expression of melanopsin and clock genes in Xenopus laevis melanophores and their modulation by melatonin. Braz J Med Biol Res (2012) 0.76
The rat cerebral vasculature exhibits time-of-day-dependent oscillations in circadian clock genes and vascular function that are attenuated following obstructive sleep apnea. J Cereb Blood Flow Metab (2016) 0.75
Are cardiometabolic and endocrine abnormalities linked to sleep difficulties in schizophrenia? A hypothesis driven review. Clin Psychopharmacol Neurosci (2012) 0.75
The vascular clock system generates the intrinsic circadian rhythm of vascular contractility. J Smooth Muscle Res (2015) 0.75
Mining for novel candidate clock genes in the circadian regulatory network. BMC Syst Biol (2015) 0.75
Temporal variation of cardiovascular diseases: an internal biological rhythm disruption may play a role? N Am J Med Sci (2013) 0.75
Temporal partitioning of cardiac metabolism by the cardiomyocyte circadian clock. Exp Physiol (2016) 0.75
Circadian Control of Cardiac Metabolism: Physiologic Roles and Pathologic Implications. Methodist Debakey Cardiovasc J (2017) 0.75
Multiple recurrent de novo CNVs, including duplications of the 7q11.23 Williams syndrome region, are strongly associated with autism. Neuron (2011) 10.61
High-resolution genomic profiling of chromosomal aberrations using Infinium whole-genome genotyping. Genome Res (2006) 10.45
Circadian rhythms from multiple oscillators: lessons from diverse organisms. Nat Rev Genet (2005) 6.87
Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation. PLoS Biol (2007) 5.48
Hydrogen sulfide attenuates myocardial ischemia-reperfusion injury by preservation of mitochondrial function. Proc Natl Acad Sci U S A (2007) 5.36
Hematopoietic fingerprints: an expression database of stem cells and their progeny. Cell Stem Cell (2007) 4.06
Molecular signatures of proliferation and quiescence in hematopoietic stem cells. PLoS Biol (2004) 3.94
Clinical implementation of chromosomal microarray analysis: summary of 2513 postnatal cases. PLoS One (2007) 3.53
A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis. Science (2011) 3.49
Development and validation of a CGH microarray for clinical cytogenetic diagnosis. Genet Med (2005) 3.39
Activation of multiple proto-oncogenic tyrosine kinases in breast cancer via loss of the PTPN12 phosphatase. Cell (2011) 3.27
Reduced mitochondrial oxidative capacity and increased mitochondrial uncoupling impair myocardial energetics in obesity. Circulation (2005) 3.22
A road map for efficient and reliable human genome epidemiology. Nat Genet (2006) 3.21
vrille, Pdp1, and dClock form a second feedback loop in the Drosophila circadian clock. Cell (2003) 3.01
Detection of clinically relevant exonic copy-number changes by array CGH. Hum Mutat (2010) 2.93
22q11.2 distal deletion: a recurrent genomic disorder distinct from DiGeorge syndrome and velocardiofacial syndrome. Am J Hum Genet (2008) 2.71
Cardiac mitochondria in heart failure: decrease in respirasomes and oxidative phosphorylation. Cardiovasc Res (2008) 2.66
A renewable tissue resource of phenotypically stable, biologically and ethnically diverse, patient-derived human breast cancer xenograft models. Cancer Res (2013) 2.63
Adaptation and maladaptation of the heart in diabetes: Part I: general concepts. Circulation (2002) 2.61
Reporting, appraising, and integrating data on genotype prevalence and gene-disease associations. Am J Epidemiol (2002) 2.56
Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression. J Clin Invest (2002) 2.53
Short communication: ischemia/reperfusion tolerance is time-of-day-dependent: mediation by the cardiomyocyte circadian clock. Circ Res (2009) 2.38
Bacterial artificial chromosome-emulation oligonucleotide arrays for targeted clinical array-comparative genomic hybridization analyses. Genet Med (2008) 2.36
PER-dependent rhythms in CLK phosphorylation and E-box binding regulate circadian transcription. Genes Dev (2006) 2.31
Increased hepatic CD36 expression contributes to dyslipidemia associated with diet-induced obesity. Diabetes (2007) 2.24
Microvascular hyperpermeability in caveolin-1 (-/-) knock-out mice. Treatment with a specific nitric-oxide synthase inhibitor, L-NAME, restores normal microvascular permeability in Cav-1 null mice. J Biol Chem (2002) 2.23
Circadian clocks in antennal neurons are necessary and sufficient for olfaction rhythms in Drosophila. Curr Biol (2004) 2.20
Disruption of the circadian clock within the cardiomyocyte influences myocardial contractile function, metabolism, and gene expression. Am J Physiol Heart Circ Physiol (2007) 2.17
Activation of AMP-activated protein kinase inhibits protein synthesis associated with hypertrophy in the cardiac myocyte. J Biol Chem (2004) 2.16
Apolipoprotein E and progression of chronic kidney disease. JAMA (2005) 2.14
Identification of de novo copy number variants associated with human disorders of sexual development. PLoS One (2010) 2.14
Rare copy number variants disrupt genes regulating vascular smooth muscle cell adhesion and contractility in sporadic thoracic aortic aneurysms and dissections. Am J Hum Genet (2010) 2.07
VRILLE feeds back to control circadian transcription of Clock in the Drosophila circadian oscillator. Neuron (2003) 2.07
Protein interactome reveals converging molecular pathways among autism disorders. Sci Transl Med (2011) 2.04
Mouse models of MeCP2 disorders share gene expression changes in the cerebellum and hypothalamus. Hum Mol Genet (2009) 2.00
Genomic imbalances in neonates with birth defects: high detection rates by using chromosomal microarray analysis. Pediatrics (2008) 2.00
Retroviral vector insertion sites associated with dominant hematopoietic clones mark "stemness" pathways. Blood (2006) 1.98
The cardiomyocyte circadian clock: emerging roles in health and disease. Circ Res (2010) 1.94
Microarray-based CGH detects chromosomal mosaicism not revealed by conventional cytogenetics. Am J Med Genet A (2007) 1.85
A common X-linked inborn error of carnitine biosynthesis may be a risk factor for nondysmorphic autism. Proc Natl Acad Sci U S A (2012) 1.85
Platelet microRNA-mRNA coexpression profiles correlate with platelet reactivity. Blood (2011) 1.83
Human platelet microRNA-mRNA networks associated with age and gender revealed by integrated plateletomics. Blood (2014) 1.81
Clinical use of array comparative genomic hybridization (aCGH) for prenatal diagnosis in 300 cases. Prenat Diagn (2009) 1.78
Genetic variation in soluble epoxide hydrolase (EPHX2) and risk of coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) study. Hum Mol Genet (2006) 1.74
Glucose-6-phosphate dehydrogenase-derived NADPH fuels superoxide production in the failing heart. J Mol Cell Cardiol (2006) 1.73
Carnitine palmitoyl transferase-I inhibition prevents ventricular remodeling and delays decompensation in pacing-induced heart failure. Cardiovasc Res (2005) 1.70
Regulation of gustatory physiology and appetitive behavior by the Drosophila circadian clock. Curr Biol (2010) 1.68
Western diet, but not high fat diet, causes derangements of fatty acid metabolism and contractile dysfunction in the heart of Wistar rats. Biochem J (2007) 1.67
Early patterns of gene expression correlate with the humoral immune response to influenza vaccination in humans. J Infect Dis (2011) 1.67
A functional genomics strategy reveals clockwork orange as a transcriptional regulator in the Drosophila circadian clock. Genes Dev (2007) 1.66
Mouse let-7 miRNA populations exhibit RNA editing that is constrained in the 5'-seed/ cleavage/anchor regions and stabilize predicted mmu-let-7a:mRNA duplexes. Genome Res (2008) 1.66
Bioinformatic profiling of the transcriptional response of adult rat cardiomyocytes to distinct fatty acids. J Lipid Res (2008) 1.63
Prenatal diagnosis of chromosomal abnormalities using array-based comparative genomic hybridization. Genet Med (2006) 1.63
The emergence of networks in human genome epidemiology: challenges and opportunities. Epidemiology (2007) 1.61
Induction of NFATc2 expression by interleukin 6 promotes T helper type 2 differentiation. J Exp Med (2002) 1.61
Circadian oscillators of Drosophila and mammals. J Cell Sci (2006) 1.59
Low carbohydrate/high-fat diet attenuates cardiac hypertrophy, remodeling, and altered gene expression in hypertension. Hypertension (2006) 1.56
Increased glucose uptake and oxidation in mouse hearts prevent high fatty acid oxidation but cause cardiac dysfunction in diet-induced obesity. Circulation (2009) 1.55
Association between adiponectin, insulin resistance, and endometrial cancer. Cancer (2006) 1.55
Identification of novel deletions of 15q11q13 in Angelman syndrome by array-CGH: molecular characterization and genotype-phenotype correlations. Eur J Hum Genet (2007) 1.52
Differential effects of saturated and unsaturated fatty acid diets on cardiomyocyte apoptosis, adipose distribution, and serum leptin. Am J Physiol Heart Circ Physiol (2006) 1.52
A DOUBLETIME kinase binding domain on the Drosophila PERIOD protein is essential for its hyperphosphorylation, transcriptional repression, and circadian clock function. Mol Cell Biol (2007) 1.52
Validation of echocardiographic methods for assessing left ventricular dysfunction in rats with myocardial infarction. Am J Physiol Heart Circ Physiol (2004) 1.52
CVT-4325 inhibits myocardial fatty acid uptake and improves left ventricular systolic function without increasing myocardial oxygen consumption in dogs with chronic heart failure. Cardiovasc Drugs Ther (2007) 1.52
Identification of chromosome abnormalities in subtelomeric regions by microarray analysis: a study of 5,380 cases. Am J Med Genet A (2008) 1.51
Evidence for diversity in transcriptional profiles of single hematopoietic stem cells. PLoS Genet (2006) 1.51
Phosphorylation of NFATc4 by p38 mitogen-activated protein kinases. Mol Cell Biol (2002) 1.50
Paradoxical downregulation of the glucose oxidation pathway despite enhanced flux in severe heart failure. J Mol Cell Cardiol (2004) 1.49
Exercise dose, exercise adherence, and associated health outcomes in the TIGER study. Med Sci Sports Exerc (2014) 1.49
Apolipoprotein E gene and early age-related maculopathy: the Atherosclerosis Risk in Communities Study. Ophthalmology (2006) 1.48
Light and temperature control the contribution of specific DN1 neurons to Drosophila circadian behavior. Curr Biol (2010) 1.47
Energy metabolism in the normal and failing heart: potential for therapeutic interventions. Heart Fail Rev (2002) 1.47
DN1(p) circadian neurons coordinate acute light and PDF inputs to produce robust daily behavior in Drosophila. Curr Biol (2010) 1.47
Inducible re-expression of HEXIM1 causes physiological cardiac hypertrophy in the adult mouse. Cardiovasc Res (2013) 1.45
Role of genomic architecture in PLP1 duplication causing Pelizaeus-Merzbacher disease. Hum Mol Genet (2006) 1.45
Generalized equations for estimating DXA percent fat of diverse young women and men: the TIGER study. Med Sci Sports Exerc (2010) 1.45
A role for the adult fat body in Drosophila male courtship behavior. PLoS Genet (2007) 1.45
The intrinsic circadian clock within the cardiomyocyte. Am J Physiol Heart Circ Physiol (2005) 1.42
Partial loss of ataxin-1 function contributes to transcriptional dysregulation in spinocerebellar ataxia type 1 pathogenesis. PLoS Genet (2010) 1.42
Development of a comparative genomic hybridization microarray and demonstration of its utility with 25 well-characterized 1p36 deletions. Hum Mol Genet (2003) 1.42
The human gene map for performance and health-related fitness phenotypes: the 2005 update. Med Sci Sports Exerc (2006) 1.42