Published in Cancer Res on September 15, 1991
ABCG2: a perspective. Adv Drug Deliv Rev (2008) 1.97
Defective acidification in human breast tumor cells and implications for chemotherapy. J Exp Med (1998) 1.89
Examination by laser scanning confocal fluorescence imaging microscopy of the subcellular localisation of anthracyclines in parent and multidrug resistant cell lines. Br J Cancer (1993) 1.34
Multifunctional nanoparticles delivering small interfering RNA and doxorubicin overcome drug resistance in cancer. J Biol Chem (2010) 1.28
Broad distribution of the multidrug resistance-related vault lung resistance protein in normal human tissues and tumors. Am J Pathol (1996) 1.17
Genistein modulates the decreased drug accumulation in non-P-glycoprotein mediated multidrug resistant tumour cells. Br J Cancer (1993) 1.08
Confocal microscopy of idarubicin localisation in sensitive and multidrug-resistant bladder cancer cell lines. Br J Cancer (1996) 1.06
Proton pump inhibitors as anti vacuolar-ATPases drugs: a novel anticancer strategy. J Exp Clin Cancer Res (2010) 1.05
Acute doxorubicin insult in the mouse ovary is cell- and follicle-type dependent. PLoS One (2012) 0.89
Delivery of intracellular-acting biologics in pro-apoptotic therapies. Curr Pharm Des (2011) 0.87
Modulation of doxorubicin resistance in a doxorubicin-resistant human leukaemia cell by an immunoliposome targeting transferring receptor. Br J Cancer (1997) 0.85
Macrocyclic pyridyl polyoxazoles: selective RNA and DNA G-quadruplex ligands as antitumor agents. J Med Chem (2010) 0.85
Low-level doxorubicin resistance in P-glycoprotein-negative human pancreatic tumour PSN1/ADR cells implicates a brefeldin A-sensitive mechanism of drug extrusion. Br J Cancer (1996) 0.85
Changes in subcellular doxorubicin distribution and cellular accumulation alone can largely account for doxorubicin resistance in SW-1573 lung cancer and MCF-7 breast cancer multidrug resistant tumour cells. Br J Cancer (1993) 0.84
Synthesis of N-substituted 5-[2-(N-alkylamino)ethyl]dibenzo[c,h][1,6]naphthyridines as novel topoisomerase I-targeting antitumor agents. Bioorg Med Chem (2008) 0.83
AGPAT9 suppresses cell growth, invasion and metastasis by counteracting acidic tumor microenvironment through KLF4/LASS2/V-ATPase signaling pathway in breast cancer. Oncotarget (2015) 0.81
Vault-related resistance to anticancer drugs determined by the expression of the major vault protein LRP. Cytotechnology (1998) 0.80
Macrocyclic biphenyl tetraoxazoles: synthesis, evaluation as G-quadruplex stabilizers and cytotoxic activity. Bioorg Med Chem (2013) 0.79
Subcellular distribution of epothilones in human tumor cells. Proc Natl Acad Sci U S A (2001) 0.79
Intracellular distribution of anthracyclines in drug resistant cells. Cytotechnology (1998) 0.79
Dual mechanism of daunorubicin-induced cell death in both sensitive and MDR-resistant HL-60 cells. Br J Cancer (1999) 0.77
Photochemical internalization-mediated delivery of chemotherapeutic agents in human breast tumor cell lines. J Environ Pathol Toxicol Oncol (2012) 0.77
Multidrug resistance circumvention by a new triazinoaminopiperidine derivative S9788 in vitro: definition of the optimal schedule and comparison with verapamil. Br J Cancer (1994) 0.77
Do glutathione and related enzymes play a role in drug resistance in small cell lung cancer cell lines? Br J Cancer (1993) 0.77
The Emerging Role of Extracellular Vesicle-Mediated Drug Resistance in Cancers: Implications in Advanced Prostate Cancer. Biomed Res Int (2015) 0.77
Intracellular localisation studies of doxorubicin and Victoria Blue BO in EMT6-S and EMT6-R cells using confocal microscopy. Cytotechnology (2002) 0.75
12-Substituted 2,3-dimethoxy-8,9-methylenedioxybenzo[i]phenanthridines as novel topoisomerase I-targeting antitumor agents. Bioorg Med Chem (2009) 0.75
Macrocyclic pyridyl polyoxazoles: structure-activity studies of the aminoalkyl side-chain on G-quadruplex stabilization and cytotoxic activity. Molecules (2013) 0.75
11-Substituted 2,3-dimethoxy-8,9-methylenedioxybenzo[i]phenanthridine derivatives as novel topoisomerase I-targeting agents. Bioorg Med Chem (2008) 0.75
Novel topoisomerase I-targeting antitumor agents synthesized from the N,N,N-trimethylammonium derivative of ARC-111, 5H-2,3-dimethoxy-8,9-methylenedioxy-5-[(2-N,N,N-trimethylammonium)ethyl]dibenzo[c,h][1,6]naphthyridin-6-one iodide. Eur J Med Chem (2009) 0.75
Artemisinins target the SERCA of Plasmodium falciparum. Nature (2003) 7.72
Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation. EMBO J (2001) 5.29
Plasmodium falciparum: in vitro studies of the pharmacodynamic properties of drugs used for the treatment of severe malaria. Exp Parasitol (1993) 4.98
The pfmdr1 gene is associated with a multidrug-resistant phenotype in Plasmodium falciparum from the western border of Thailand. Antimicrob Agents Chemother (1999) 4.64
Amodiaquine-artesunate versus amodiaquine for uncomplicated Plasmodium falciparum malaria in African children: a randomised, multicentre trial. Lancet (2002) 4.47
Expression of the CD34 gene in vascular endothelial cells. Blood (1990) 4.41
Pre-referral rectal artesunate to prevent death and disability in severe malaria: a placebo-controlled trial. Lancet (2008) 4.35
Severe falciparum malaria in children: current understanding of pathophysiology and supportive treatment. Pharmacol Ther (1998) 3.57
Topotecan versus cyclophosphamide, doxorubicin, and vincristine for the treatment of recurrent small-cell lung cancer. J Clin Oncol (1999) 3.48
Comparison of methods for the rapid laboratory assessment of children with malaria. Am J Trop Med Hyg (2001) 3.44
Albumin phylogeny for clawed frogs (Xenopus). Science (1977) 3.12
HIV-1 suppression during acute scrub-typhus infection. Lancet (2000) 3.08
Severe hypoglycemia and hyperinsulinemia in falciparum malaria. N Engl J Med (1983) 3.07
Antimalarial drugs reduce cytoadherence and rosetting Plasmodium falciparum. J Infect Dis (1996) 2.59
Fatal infantile cardioencephalomyopathy with COX deficiency and mutations in SCO2, a COX assembly gene. Nat Genet (1999) 2.59
Aquaporin-4 expression is increased in oedematous human brain tumours. J Neurol Neurosurg Psychiatry (2002) 2.42
The effect of localized injection of adjuvant material on the draining lymph node. II. Circulating lymphocytes. Immunology (1970) 2.19
The looming epidemic of diabetes-associated tuberculosis: learning lessons from HIV-associated tuberculosis. Int J Tuberc Lung Dis (2011) 2.19
Segregation of lymphocyte populations through differential migration. Nature (1969) 2.09
A BMP homolog acts as a dose-dependent regulator of body size and male tail patterning in Caenorhabditis elegans. Development (1999) 2.08
A brief illustrated guide to the ultrastructure of Plasmodium falciparum asexual blood stages. Parasitol Today (2000) 2.04
The effect of localized injection of adjuvant material on the draining lymph node. I. Histology. Immunology (1970) 2.00
Mitotic mechanisms in Alzheimer's disease? J Cell Biol (1996) 2.00
Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain. J Neurosci (1997) 2.00
Notes on the preparation and assay of anti-lymphocytic serum for use in mice. Immunology (1968) 1.96
Clinical features and outcome of severe malaria in Gambian children. Clin Infect Dis (1995) 1.96
Treatment of malaria: some considerations and limitations of the current methods of assessment. Trans R Soc Trop Med Hyg (1990) 1.91
Immunologic dysfunction in heroin addicts. Arch Intern Med (1974) 1.77
Pioneer axon guidance by UNC-129, a C. elegans TGF-beta. Science (1998) 1.76
Artemisinins. Postgrad Med J (2005) 1.66
Magnetic resonance imaging of the brain in patients with cerebral malaria. Clin Infect Dis (1995) 1.65
Activated Notch1 signaling cooperates with papillomavirus oncogenes in transformation and generates resistance to apoptosis on matrix withdrawal through PKB/Akt. Virology (2001) 1.63
Operantly conditioned patterns on precentral unit activity and correlated responses in adjacent cells and contralateral muscles. J Neurophysiol (1973) 1.63
A randomised trial of oral versus intravenous topotecan in patients with relapsed epithelial ovarian cancer. Eur J Cancer (2002) 1.62
Increased aquaporin 1 water channel expression in human brain tumours. Br J Cancer (2002) 1.61
Histopathological effects in mice of heterologous antilymphocyte serum. J Exp Med (1968) 1.61
Role of cerebral arterial blood in the regulation of brain temperature in the monkey. Am J Physiol (1968) 1.59
Intraerythrocytic Plasmodium falciparum expresses a high affinity facilitative hexose transporter. J Biol Chem (1999) 1.59
Cerebral anaerobic glycolysis and reduced cerebral oxygen transport in human cerebral malaria. Lancet (1988) 1.55
Effects of heterologous anti-lymphocyte serum on the distribution of 51-Cr-labelled lymph node cells in mice. Immunology (1968) 1.52
Imparied lymphocyte responsiveness in inflammatory bowel disease. Gastroenterology (1973) 1.51
The link between integration and expression of human papillomavirus type 16 genomes and cellular changes in the evolution of cervical intraepithelial neoplastic lesions. J Gen Virol (1997) 1.51
Open comparison of intramuscular chloroquine and quinine in children with severe chloroquine-sensitive falciparum malaria. Lancet (1989) 1.50
The effect of localized injection of adjuvant material on the draining lymph node. 3. Thymus dependence. J Immunol (1972) 1.48
A model for the emergence of cooperation, interdependence, and structure in evolving networks. Proc Natl Acad Sci U S A (2001) 1.48
Cytoplasmic network arrays demonstrated by immunolocalization using antibodies to a high molecular weight protein present in cytoskeletal preparations from cultured cells. Exp Cell Res (1982) 1.47
Architectural organization in the interphase nucleus of the protozoan Trypanosoma brucei: location of telomeres and mini-chromosomes. EMBO J (1990) 1.44
Short-term lymphocyte cultures in regional enteritis. Lancet (1970) 1.43
Antimalarial drugs: recent advances in molecular determinants of resistance and their clinical significance. Cell Mol Life Sci (2006) 1.42
Hexose permeation pathways in Plasmodium falciparum-infected erythrocytes. Proc Natl Acad Sci U S A (2000) 1.41
Quinine disposition kinetics. Br J Clin Pharmacol (1983) 1.41
Prospective assessment of two-stage testing for Clostridium difficile. J Hosp Infect (2010) 1.40
Anergy to dinitrochlorobenzene and depression of T-lymphocytes in Crohn's disease and ulcerative colitis. Gut (1976) 1.38
Mycobacterium tuberculosis expresses a novel pH-dependent divalent cation transporter belonging to the Nramp family. J Exp Med (1999) 1.36
Topotecan for the treatment of advanced epithelial ovarian cancer: an open-label phase II study in patients treated after prior chemotherapy that contained cisplatin or carboplatin and paclitaxel. J Clin Oncol (1998) 1.35
Sensory and motor responses of precentral cortex cells during comparable passive and active joint movements. J Neurophysiol (1980) 1.32
The influence of the nasal mucosa and the carotid rete upon hypothalamic temperature in sheep. J Physiol (1968) 1.30
Assessment of pfmdr 1 gene copy number by tandem competitive polymerase chain reaction. Mol Biochem Parasitol (1997) 1.29
Oscillations and temporal signalling in cells. Phys Biol (2007) 1.28
Effects of lymphoid depletion on the distribution of 51Cr-labeled lymph node cells in mice. Transplantation (1971) 1.23
The major histocompatibility complex class I antigen-binding protein p88 is the product of the calnexin gene. Proc Natl Acad Sci U S A (1992) 1.22
Inhibitors of carbohydrate processing: A new class of anticancer agents. Clin Cancer Res (1995) 1.22
Molecular mechanisms of brain tumor edema. Neuroscience (2004) 1.21
Consultation meeting on tuberculosis and diabetes mellitus: meeting summary and recommendations. Int J Tuberc Lung Dis (2010) 1.21
Erythrocyte sequestration and anemia in severe falciparum malaria. Analysis of acute changes in venous hematocrit using a simple mathematical model. J Clin Invest (1990) 1.18
Pharmacokinetic and pharmacodynamic issues in the treatment of parasitic infections. Eur J Clin Microbiol Infect Dis (2004) 1.17
Glucose and lactate kinetics in children with severe malaria. J Clin Endocrinol Metab (2000) 1.17
The plastid in Plasmodium falciparum asexual blood stages: a three-dimensional ultrastructural analysis. Protist (1999) 1.17
Metal ion homeostasis and intracellular parasitism. Mol Microbiol (1998) 1.17
A comparative study of the role of the cerebral arterial blood in the regulation of brain temperature in five mammals. Brain Res (1969) 1.17
Expression of thrombospondin-related anonymous protein in Plasmodium falciparum sporozoites. Lancet (1992) 1.16
Maternally inherited hearing loss in a large kindred with a novel T7511C mutation in the mitochondrial DNA tRNA(Ser(UCN)) gene. Neurology (1999) 1.16
Brain cooling in endotherms in heat and exercise. Annu Rev Physiol (1982) 1.15
Distribution of labeled lymph node cells in mice during the lymphocytosis induced by Bordetella pertussis. J Exp Med (1972) 1.14
Factors associated with the catastrophic decline of a cloudforest frog fauna in Guatemala. Rev Biol Trop (2004) 1.14
Severe malaria: metabolic complications. Curr Mol Med (2006) 1.11
Effect of verapamil and other agents on the distribution of anthracyclines and on reversal of drug resistance. Cancer Res (1987) 1.11
Intracellular distribution and pharmacokinetics of daunorubicin in anthracycline-sensitive and -resistant HL-60 cells. Cancer Res (1989) 1.09
Diuretic and thermoregulatory responses to preoptic cooling in the monkey. Am J Physiol (1968) 1.09
Antimalarial multi-drug resistance in Asia: mechanisms and assessment. Curr Top Microbiol Immunol (2005) 1.08
Capping and stabilizing chronic intravascular cannulae. J Appl Physiol (1968) 1.08
Cerebral sparganosis: a diagnostic challenge. Br J Neurosurg (2008) 1.08
Erythrocyte survival in severe falciparum malaria. Acta Trop (1991) 1.08
Telomere-related sequences at interstitial sites in the human genome. Genomics (1990) 1.07
The role of Notch signaling in human cervical cancer: implications for solid tumors. Oncogene (2008) 1.07
Ultrastructure of rhoptry development in Plasmodium falciparum erythrocytic schizonts. Parasitology (2000) 1.07
T and B lymphocytes and cutaneous anergy in inflammatory bowel disease. Ann N Y Acad Sci (1976) 1.07
Intracranial pressure in childhood cerebral malaria. Trans R Soc Trop Med Hyg (1991) 1.06
Chemotherapy for advanced sarcoma: therapeutic decisions and modalities. Semin Oncol (1997) 1.06
Variability of skin temperature in the waking monkey. Am J Physiol (1976) 1.06
Effect of duration of exposure to verapamil on vincristine activity against multidrug-resistant human leukemic cell lines. Cancer Res (1989) 1.04
Isolation and characterization of an anthracycline-resistant human leukemic cell line. Cancer Res (1985) 1.03
Functional roles of the transcription factor Oct-2A and the high mobility group protein I/Y in HLA-DRA gene expression. J Exp Med (1995) 1.03