Published in Int J Cancer on November 01, 2006
The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2. Genes Dev (2008) 15.01
The transcription factor ZEB1 (deltaEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity. Oncogene (2007) 4.90
A natural antisense transcript regulates Zeb2/Sip1 gene expression during Snail1-induced epithelial-mesenchymal transition. Genes Dev (2008) 3.85
The transcriptional corepressor CtBP: a foe of multiple tumor suppressors. Cancer Res (2009) 2.02
Expanding roles of ZEB factors in tumorigenesis and tumor progression. Am J Cancer Res (2011) 1.26
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Either ZEB1 or ZEB2/SIP1 can play a central role in regulating the Epstein-Barr virus latent-lytic switch in a cell-type-specific manner. J Virol (2010) 1.17
TMPRSS2/ERG promotes epithelial to mesenchymal transition through the ZEB1/ZEB2 axis in a prostate cancer model. PLoS One (2011) 1.15
ZEB1 coordinately regulates laminin-332 and {beta}4 integrin expression altering the invasive phenotype of prostate cancer cells. J Biol Chem (2010) 1.12
Cellular microRNAs 200b and 429 regulate the Epstein-Barr virus switch between latency and lytic replication. J Virol (2010) 1.09
The tight junction associated signalling proteins ZO-1 and ZONAB regulate retinal pigment epithelium homeostasis in mice. PLoS One (2010) 0.99
MiR-101 suppresses the epithelial-to-mesenchymal transition by targeting ZEB1 and ZEB2 in ovarian carcinoma. Oncol Rep (2014) 0.98
Inhibitory effects of transcription factor Ikaros on the expression of liver cancer stem cell marker CD133 in hepatocellular carcinoma. Oncotarget (2014) 0.93
Vitamin D Is a Multilevel Repressor of Wnt/b-Catenin Signaling in Cancer Cells. Cancers (Basel) (2013) 0.93
Epithelial Plasticity in Cancer: Unmasking a MicroRNA Network for TGF-β-, Notch-, and Wnt-Mediated EMT. J Oncol (2015) 0.91
Interaction with cyclin H/cyclin-dependent kinase 7 (CCNH/CDK7) stabilizes C-terminal binding protein 2 (CtBP2) and promotes cancer cell migration. J Biol Chem (2013) 0.88
Cooperation of p300 and PCAF in the control of microRNA 200c/141 transcription and epithelial characteristics. PLoS One (2012) 0.88
Polyethylene glycol-mediated colorectal cancer chemoprevention: roles of epidermal growth factor receptor and Snail. Mol Cancer Ther (2008) 0.87
Small Molecule, NSC95397, Inhibits the CtBP1-Protein Partner Interaction and CtBP1-Mediated Transcriptional Repression. J Biomol Screen (2014) 0.85
C-Terminal Binding Protein: A Molecular Link between Metabolic Imbalance and Epigenetic Regulation in Breast Cancer. Int J Cell Biol (2013) 0.84
Using components of the vitamin D pathway to prevent and treat colon cancer. Nutr Rev (2012) 0.83
Dissecting the action of an evolutionary conserved non-coding region on renin promoter activity. Nucleic Acids Res (2007) 0.83
Sensory epithelial cells acquire features of prosensory cells via epithelial to mesenchymal transition. Stem Cells Dev (2011) 0.82
Hepatocyte growth factor increases the invasive potential of PC-3 human prostate cancer cells via an ERK/MAPK and Zeb-1 signaling pathway. Oncol Lett (2015) 0.82
Loss of full length CtBP1 expression enhances the invasive potential of human melanoma. BMC Cancer (2009) 0.82
ZEB1 and TCF4 reciprocally modulate their transcriptional activities to regulate Wnt target gene expression. Oncogene (2015) 0.80
The miR-644a/CTBP1/p53 axis suppresses drug resistance by simultaneous inhibition of cell survival and epithelial-mesenchymal transition in breast cancer. Oncotarget (2016) 0.78
CtBP2 proteome: Role of CtBP in E2F7-mediated repression and cell proliferation. Genes Cancer (2014) 0.78
The corepressor CTBP2 is a coactivator of retinoic acid receptor/retinoid X receptor in retinoic acid signaling. Mol Cell Biol (2013) 0.78
The role of Snail1 transcription factor in colorectal cancer progression and metastasis. Contemp Oncol (Pozn) (2015) 0.78
Vitamin D and the Epithelial to Mesenchymal Transition. Stem Cells Int (2016) 0.78
Metabolic Reprogramming Regulates the Proliferative and Inflammatory Phenotype of Adventitial Fibroblasts in Pulmonary Hypertension Through the Transcriptional Corepressor C-Terminal Binding Protein-1. Circulation (2016) 0.77
Regulation of VDR Expression in Apc-Mutant Mice, Human Colon Cancers and Adenomas. Cancer Prev Res (Phila) (2015) 0.77
ZEB1 Mediates Drug Resistance and EMT in p300-Deficient CRC. J Cancer (2017) 0.75
Vitamin D receptor signaling and pancreatic cancer cell EMT. Curr Pharm Des (2015) 0.75
Homeodomain-interacting protein kinase 2 (HIPK2): a promising target for anti-cancer therapies. Oncotarget (2017) 0.75
Disrupted cooperation between transcription factors across diverse cancer types. BMC Genomics (2016) 0.75
1α,25(OH)₂D₃ Suppresses the Migration of Ovarian Cancer SKOV-3 Cells through the Inhibition of Epithelial-Mesenchymal Transition. Int J Mol Sci (2016) 0.75
P300 promotes migration, invasion and epithelial-mesenchymal transition in a nasopharyngeal carcinoma cell line. Oncol Lett (2016) 0.75
C-terminal binding protein-2 promotes cell proliferation and migration in breast cancer via suppression of p16INK4A. Oncotarget (2017) 0.75
Investigating the Molecular Basis of PPCD3: Characterization of ZEB1 Regulation of COL4A3 Expression. Invest Ophthalmol Vis Sci (2016) 0.75
Role of RbBP5 and H3K4me3 in the vicinity of Snail transcription start site during epithelial-mesenchymal transition in prostate cancer cell. Oncotarget (2016) 0.75
Holliday junction trap shows how cells use recombination and a junction-guardian role of RecQ helicase. Sci Adv (2016) 0.75
Ginsenoside Rb1 inhibits hypoxia-induced epithelial-mesenchymal transition in ovarian cancer cells by regulating microRNA-25. Exp Ther Med (2017) 0.75
Revisiting epithelial-mesenchymal transition in cancer metastasis: the connection between epithelial plasticity and stemness. Mol Oncol (2017) 0.75
Petilla terminology: nomenclature of features of GABAergic interneurons of the cerebral cortex. Nat Rev Neurosci (2008) 8.14
Drought sensitivity of the Amazon rainforest. Science (2009) 7.27
Profiling essential genes in human mammary cells by multiplex RNAi screening. Science (2008) 4.51
A natural antisense transcript regulates Zeb2/Sip1 gene expression during Snail1-induced epithelial-mesenchymal transition. Genes Dev (2008) 3.85
The Wnt antagonist DICKKOPF-1 gene is a downstream target of beta-catenin/TCF and is downregulated in human colon cancer. Oncogene (2005) 3.01
p120 Catenin-associated Fer and Fyn tyrosine kinases regulate beta-catenin Tyr-142 phosphorylation and beta-catenin-alpha-catenin Interaction. Mol Cell Biol (2003) 2.58
Polycomb complex 2 is required for E-cadherin repression by the Snail1 transcription factor. Mol Cell Biol (2008) 2.57
Phosphorylation regulates the subcellular location and activity of the snail transcriptional repressor. Mol Cell Biol (2003) 2.46
Regulation of Snail transcription during epithelial to mesenchymal transition of tumor cells. Oncogene (2004) 2.44
Control of flowering and storage organ formation in potato by FLOWERING LOCUS T. Nature (2011) 2.32
The transcription factor SNAIL represses vitamin D receptor expression and responsiveness in human colon cancer. Nat Med (2004) 2.11
Overexpression of choline kinase is a frequent feature in human tumor-derived cell lines and in lung, prostate, and colorectal human cancers. Biochem Biophys Res Commun (2002) 2.09
Increased choline kinase activity in human breast carcinomas: clinical evidence for a potential novel antitumor strategy. Oncogene (2002) 2.09
β-catenin confers resistance to PI3K and AKT inhibitors and subverts FOXO3a to promote metastasis in colon cancer. Nat Med (2012) 2.02
Voltage-gated ion channels in the axon initial segment of human cortical pyramidal cells and their relationship with chandelier cells. Proc Natl Acad Sci U S A (2006) 1.98
E-cadherin and vitamin D receptor regulation by SNAIL and ZEB1 in colon cancer: clinicopathological correlations. Hum Mol Genet (2005) 1.95
Role of HuR in skeletal myogenesis through coordinate regulation of muscle differentiation genes. Mol Cell Biol (2003) 1.93
DeltaTAp73 upregulation correlates with poor prognosis in human tumors: putative in vivo network involving p73 isoforms, p53, and E2F-1. J Clin Oncol (2005) 1.88
Drought-mortality relationships for tropical forests. New Phytol (2010) 1.82
Promoter methylation of the PTEN gene is a common molecular change in breast cancer. Genes Chromosomes Cancer (2004) 1.82
Snail1 transcriptional repressor binds to its own promoter and controls its expression. Nucleic Acids Res (2006) 1.80
Cyfip1 is a putative invasion suppressor in epithelial cancers. Cell (2009) 1.77
Deregulated expression of miR-106a predicts survival in human colon cancer patients. Genes Chromosomes Cancer (2008) 1.75
Retracted Lysyl oxidase-like 2 deaminates lysine 4 in histone H3. Mol Cell (2012) 1.74
Repression of PTEN phosphatase by Snail1 transcriptional factor during gamma radiation-induced apoptosis. Mol Cell Biol (2008) 1.68
Kahalalide F, a new marine-derived compound, induces oncosis in human prostate and breast cancer cells. Mol Cancer Ther (2003) 1.61
Specific phosphorylation of p120-catenin regulatory domain differently modulates its binding to RhoA. Mol Cell Biol (2006) 1.50
Genetic signatures of differentiation induced by 1alpha,25-dihydroxyvitamin D3 in human colon cancer cells. Cancer Res (2003) 1.46
Intratumoral heterogeneity in microsatellite alterations in BRCA1 and PTEN regions in sporadic colorectal cancer. Ann Surg Oncol (2003) 1.45
E-cadherin controls beta-catenin and NF-kappaB transcriptional activity in mesenchymal gene expression. J Cell Sci (2008) 1.44
Ultrasound measurement of gallbladder wall thickening as a diagnostic test and prognostic indicator for severe dengue in pediatric patients. Pediatr Infect Dis J (2007) 1.42
The transcriptional factor Tcf-4 contains different binding sites for beta-catenin and plakoglobin. J Biol Chem (2001) 1.35
The hypoxia-controlled FBXL14 ubiquitin ligase targets SNAIL1 for proteasome degradation. J Biol Chem (2009) 1.35
Extracellular plasma RNA from colon cancer patients is confined in a vesicle-like structure and is mRNA-enriched. RNA (2008) 1.35
Tyrosine phosphorylation of plakoglobin causes contrary effects on its association with desmosomes and adherens junction components and modulates beta-catenin-mediated transcription. Mol Cell Biol (2003) 1.33
Epigenetics and environment: a complex relationship. J Appl Physiol (1985) (2010) 1.32
Double bouquet cell in the human cerebral cortex and a comparison with other mammals. J Comp Neurol (2005) 1.32
The Wnt antagonist DICKKOPF-1 gene is induced by 1alpha,25-dihydroxyvitamin D3 associated to the differentiation of human colon cancer cells. Carcinogenesis (2007) 1.27
MicroRNA-22 is induced by vitamin D and contributes to its antiproliferative, antimigratory and gene regulatory effects in colon cancer cells. Hum Mol Genet (2012) 1.26
Snail-dependent and -independent epithelial-mesenchymal transition in oral squamous carcinoma cells. J Histochem Cytochem (2006) 1.25
Implication of polycomb members Bmi-1, Mel-18, and Hpc-2 in the regulation of p16INK4a, p14ARF, h-TERT, and c-Myc expression in primary breast carcinomas. Clin Cancer Res (2006) 1.23
Snail2 cooperates with Snail1 in the repression of vitamin D receptor in colon cancer. Carcinogenesis (2009) 1.20
Vitamin D and colon cancer. Endocr Relat Cancer (2012) 1.20
Vitamin D regulates the phenotype of human breast cancer cells. Differentiation (2006) 1.20
Vitamin D and Wnt/beta-catenin pathway in colon cancer: role and regulation of DICKKOPF genes. Anticancer Res (2008) 1.19
Cystatin D is a candidate tumor suppressor gene induced by vitamin D in human colon cancer cells. J Clin Invest (2009) 1.19
Vitamin D receptor deficiency enhances Wnt/β-catenin signaling and tumor burden in colon cancer. PLoS One (2011) 1.17
Thyroid hormone receptors/THR genes in human cancer. Cancer Lett (2003) 1.17
Retracted Beta-catenin N- and C-terminal tails modulate the coordinated binding of adherens junction proteins to beta-catenin. J Biol Chem (2002) 1.16
Snail1 protein in the stroma as a new putative prognosis marker for colon tumours. PLoS One (2009) 1.16
Targeting epithelial-to-mesenchymal transition with Met inhibitors reverts chemoresistance in small cell lung cancer. Clin Cancer Res (2013) 1.15
Expression of thyroid hormone receptor/erbA genes is altered in human breast cancer. Oncogene (2002) 1.15
Cancer-associated fibroblast and M2 macrophage markers together predict outcome in colorectal cancer patients. Cancer Sci (2013) 1.14
Identification and rational design of novel antimicrobial peptides for plant protection. Annu Rev Phytopathol (2008) 1.13
Glucocorticoid receptor-JNK interaction mediates inhibition of the JNK pathway by glucocorticoids. EMBO J (2003) 1.11