Published in PLoS One on May 18, 2009
A p53/miRNA-34 axis regulates Snail1-dependent cancer cell epithelial-mesenchymal transition. J Cell Biol (2011) 2.19
Snail family regulation and epithelial mesenchymal transitions in breast cancer progression. J Mammary Gland Biol Neoplasia (2010) 1.76
Canonical Wnt suppressor, Axin2, promotes colon carcinoma oncogenic activity. Proc Natl Acad Sci U S A (2012) 1.23
Phosphorylation of serine 11 and serine 92 as new positive regulators of human Snail1 function: potential involvement of casein kinase-2 and the cAMP-activated kinase protein kinase A. Mol Biol Cell (2009) 1.21
Snail1 controls TGF-β responsiveness and differentiation of mesenchymal stem cells. Oncogene (2012) 1.15
The role of Snail in prostate cancer. Cell Adh Migr (2012) 1.06
The skinny on Slug. Mol Carcinog (2010) 1.06
Epigenetic control of epithelial-mesenchymal-transition in human cancer. Mol Clin Oncol (2012) 1.03
Utility of a bacterial infection model to study epithelial-mesenchymal transition, mesenchymal-epithelial transition or tumorigenesis. Oncogene (2013) 1.02
Nuclear Snail1 and nuclear ZEB1 protein expression in invasive and intraductal human breast carcinomas. Hum Pathol (2011) 0.98
Down-regulation of CDH1 is associated with expression of SNAI1 in colorectal adenomas. PLoS One (2012) 0.91
SNAI1 expression and the mesenchymal phenotype: an immunohistochemical study performed on 46 cases of oral squamous cell carcinoma. BMC Clin Pathol (2010) 0.90
Analysis of Snail-1, E-cadherin and claudin-1 expression in colorectal adenomas and carcinomas. Int J Mol Sci (2012) 0.89
Novel snail1 target proteins in human colon cancer identified by proteomic analysis. PLoS One (2010) 0.88
TGFBR2 and BAX mononucleotide tract mutations, microsatellite instability, and prognosis in 1072 colorectal cancers. PLoS One (2011) 0.86
Site-dependent E-cadherin cleavage and nuclear translocation in a metastatic colorectal cancer model. Am J Pathol (2010) 0.85
Snail1 expression in colorectal cancer and its correlation with clinical and pathological parameters. BMC Cancer (2013) 0.83
On the origin and destination of cancer stem cells: a conceptual evaluation. Am J Cancer Res (2013) 0.82
Snail1 expression is required for sarcomagenesis. Neoplasia (2014) 0.81
Transcription factors related to epithelial mesenchymal transition in tumor center and margin in invasive lung adenocarcinoma. Int J Clin Exp Pathol (2014) 0.81
Snail and serpinA1 promote tumor progression and predict prognosis in colorectal cancer. Oncotarget (2015) 0.80
Sequencing and comparative genomic analysis of 1227 Felis catus cDNA sequences enriched for developmental, clinical and nutritional phenotypes. BMC Genomics (2012) 0.80
The role of Snail1 transcription factor in colorectal cancer progression and metastasis. Contemp Oncol (Pozn) (2015) 0.78
Stromal Modulators of TGF-β in Cancer. J Clin Med (2017) 0.76
Snail1 is required for the maintenance of the pancreatic acinar phenotype. Oncotarget (2016) 0.76
CYB5R1 links epithelial-mesenchymal transition and poor prognosis in colorectal cancer. Oncotarget (2016) 0.75
Epithelial-to-mesenchymal transition transcription factors in cancer-associated fibroblasts. Mol Oncol (2017) 0.75
Complex networks orchestrate epithelial-mesenchymal transitions. Nat Rev Mol Cell Biol (2006) 23.04
Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Nat Rev Cancer (2007) 18.69
Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis. Dev Cell (2008) 14.80
Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition. Nat Cell Biol (2004) 9.80
The microenvironment of the tumour-host interface. Nature (2001) 9.17
Variable beta-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment. Proc Natl Acad Sci U S A (2001) 7.99
Of extracellular matrix, scaffolds, and signaling: tissue architecture regulates development, homeostasis, and cancer. Annu Rev Cell Dev Biol (2006) 6.64
The transcriptional repressor Snail promotes mammary tumor recurrence. Cancer Cell (2005) 5.81
Cancer statistics, 1997. CA Cancer J Clin (1997) 5.22
A Wnt-Axin2-GSK3beta cascade regulates Snail1 activity in breast cancer cells. Nat Cell Biol (2006) 4.55
Wnt-dependent regulation of the E-cadherin repressor snail. J Biol Chem (2005) 3.03
Snail activation disrupts tissue homeostasis and induces fibrosis in the adult kidney. EMBO J (2006) 2.80
A molecular role for lysyl oxidase-like 2 enzyme in snail regulation and tumor progression. EMBO J (2005) 2.71
Expression of Snail protein in tumor-stroma interface. Oncogene (2006) 2.68
Phosphorylation regulates the subcellular location and activity of the snail transcriptional repressor. Mol Cell Biol (2003) 2.46
Pak1 phosphorylation of snail, a master regulator of epithelial-to-mesenchyme transition, modulates snail's subcellular localization and functions. Cancer Res (2005) 2.09
Adaptation versus selection: the origins of metastatic behavior. Cancer Res (2007) 2.08
Repression of PTEN phosphatase by Snail1 transcriptional factor during gamma radiation-induced apoptosis. Mol Cell Biol (2008) 1.68
Lysyl oxidase-like 2 as a new poor prognosis marker of squamous cell carcinomas. Cancer Res (2008) 1.48
The E-cadherin repressor Snail is associated with lower overall survival of ovarian cancer patients. Br J Cancer (2007) 1.45
Expression and nuclear localization of Snail, an E-cadherin repressor, in adenocarcinomas of the upper gastrointestinal tract. Virchows Arch (2005) 1.33
Snail-dependent and -independent epithelial-mesenchymal transition in oral squamous carcinoma cells. J Histochem Cytochem (2006) 1.25
The E-cadherin repressor snail plays a role in tumor progression of endometrioid adenocarcinomas. Diagn Mol Pathol (2007) 1.02
Biological potential of a functional human SNAIL retrogene. J Biol Chem (2002) 0.92
The intestinal stem cell signature identifies colorectal cancer stem cells and predicts disease relapse. Cell Stem Cell (2011) 4.79
Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factor. EMBO J (2002) 3.99
A simplified laminin nomenclature. Matrix Biol (2005) 3.81
B cell-helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen. Nat Immunol (2011) 3.66
Identification of a mutation in the extracellular domain of the Epidermal Growth Factor Receptor conferring cetuximab resistance in colorectal cancer. Nat Med (2012) 3.44
Isolation and in vitro expansion of human colonic stem cells. Nat Med (2011) 3.20
A SNAIL1-SMAD3/4 transcriptional repressor complex promotes TGF-beta mediated epithelial-mesenchymal transition. Nat Cell Biol (2009) 3.12
The Wnt antagonist DICKKOPF-1 gene is a downstream target of beta-catenin/TCF and is downregulated in human colon cancer. Oncogene (2005) 3.01
Dependency of colorectal cancer on a TGF-β-driven program in stromal cells for metastasis initiation. Cancer Cell (2012) 2.94
p120 Catenin-associated Fer and Fyn tyrosine kinases regulate beta-catenin Tyr-142 phosphorylation and beta-catenin-alpha-catenin Interaction. Mol Cell Biol (2003) 2.58
Polycomb complex 2 is required for E-cadherin repression by the Snail1 transcription factor. Mol Cell Biol (2008) 2.57
Phosphorylation regulates the subcellular location and activity of the snail transcriptional repressor. Mol Cell Biol (2003) 2.46
Regulation of Snail transcription during epithelial to mesenchymal transition of tumor cells. Oncogene (2004) 2.44
EphB-ephrin-B interactions suppress colorectal cancer progression by compartmentalizing tumor cells. Nat Genet (2007) 2.33
Mesenchymal cells reactivate Snail1 expression to drive three-dimensional invasion programs. J Cell Biol (2009) 1.99
The expression levels of the transcriptional regulators p300 and CtBP modulate the correlations between SNAIL, ZEB1, E-cadherin and vitamin D receptor in human colon carcinomas. Int J Cancer (2006) 1.91
Laminin isoforms in tumor invasion, angiogenesis and metastasis. Semin Cancer Biol (2002) 1.83
Fibronectin fibrillogenesis regulates three-dimensional neovessel formation. Genes Dev (2008) 1.81
Snail1 transcriptional repressor binds to its own promoter and controls its expression. Nucleic Acids Res (2006) 1.80
Host cell-derived cardiomyocytes in sex-mismatch cardiac allografts. Cardiovasc Res (2002) 1.76
Retracted Lysyl oxidase-like 2 deaminates lysine 4 in histone H3. Mol Cell (2012) 1.74
Repression of PTEN phosphatase by Snail1 transcriptional factor during gamma radiation-induced apoptosis. Mol Cell Biol (2008) 1.68
Nodal yield, morbidity, and recurrence after central neck dissection for papillary thyroid carcinoma. Surgery (2005) 1.64
Chromatin-bound IκBα regulates a subset of polycomb target genes in differentiation and cancer. Cancer Cell (2013) 1.61
Specific phosphorylation of p120-catenin regulatory domain differently modulates its binding to RhoA. Mol Cell Biol (2006) 1.50
Consensus of the Spanish Society of Medical Oncology (SEOM) and Spanish Society of Pathology (SEAP) for HER2 testing in gastric carcinoma. Clin Transl Oncol (2011) 1.46
Key contribution of CPEB4-mediated translational control to cancer progression. Nat Med (2011) 1.37
Transcription factors zeb1, twist and snai1 in breast carcinoma. BMC Cancer (2011) 1.35
The transcriptional factor Tcf-4 contains different binding sites for beta-catenin and plakoglobin. J Biol Chem (2001) 1.35
Tyrosine phosphorylation of plakoglobin causes contrary effects on its association with desmosomes and adherens junction components and modulates beta-catenin-mediated transcription. Mol Cell Biol (2003) 1.33
Level of HER2 gene amplification predicts response and overall survival in HER2-positive advanced gastric cancer treated with trastuzumab. J Clin Oncol (2013) 1.32
Mesangial cells organize the glomerular capillaries by adhering to the G domain of laminin alpha5 in the glomerular basement membrane. J Cell Biol (2003) 1.29
Snail-dependent and -independent epithelial-mesenchymal transition in oral squamous carcinoma cells. J Histochem Cytochem (2006) 1.25
Compositional differences between infant and adult human corneal basement membranes. Invest Ophthalmol Vis Sci (2007) 1.25
The epigenetic regulators Bmi1 and Ring1B are differentially regulated in pancreatitis and pancreatic ductal adenocarcinoma. J Pathol (2009) 1.22
Retracted Beta-catenin N- and C-terminal tails modulate the coordinated binding of adherens junction proteins to beta-catenin. J Biol Chem (2002) 1.16
Ulcerative colitis induces changes on the expression of the endocannabinoid system in the human colonic tissue. PLoS One (2009) 1.16
Inhibition of laminin-8 in vivo using a novel poly(malic acid)-based carrier reduces glioma angiogenesis. Angiogenesis (2006) 1.15
Targeting epithelial-to-mesenchymal transition with Met inhibitors reverts chemoresistance in small cell lung cancer. Clin Cancer Res (2013) 1.15
Cancer-associated fibroblast and M2 macrophage markers together predict outcome in colorectal cancer patients. Cancer Sci (2013) 1.14
Acidic cysteine endoproteinase cathepsin K in the degeneration of the superficial articular hyaline cartilage in osteoarthritis. Arthritis Rheum (2002) 1.11
The EMT signaling pathways in endometrial carcinoma. Clin Transl Oncol (2012) 1.07
Antisense inhibition of laminin-8 expression reduces invasion of human gliomas in vitro. Mol Cancer Ther (2003) 1.06
Identification of the binding site for the Lutheran blood group glycoprotein on laminin alpha 5 through expression of chimeric laminin chains in vivo. J Biol Chem (2002) 1.05
Vulvar angiomyxoma, aggressive angiomyxoma, and angiomyofibroblastoma: an immunohistochemical and ultrastructural study. Ultrastruct Pathol (2006) 1.05
Podosome-like structures of non-invasive carcinoma cells are replaced in epithelial-mesenchymal transition by actin comet-embedded invadopodia. J Cell Mol Med (2009) 1.03
Vascular endothelial growth factor-A stimulates Snail expression in breast tumor cells: implications for tumor progression. Exp Cell Res (2008) 1.03
Basement membrane proteins in multiple sclerosis-associated inflammatory cuffs: potential role in influx and transport of leukocytes. J Neuropathol Exp Neurol (2005) 1.03
Laminin isoforms in human embryonic stem cells: synthesis, receptor usage and growth support. J Cell Mol Med (2008) 1.03
Tissue plasminogen activator mediates amyloid-induced neurotoxicity via Erk1/2 activation. EMBO J (2005) 1.02
OSBPL10, a novel candidate gene for high triglyceride trait in dyslipidemic Finnish subjects, regulates cellular lipid metabolism. J Mol Med (Berl) (2009) 1.02
Single-nucleotide polymorphisms in base excision repair, nucleotide excision repair, and double strand break genes as markers for response to radiotherapy in patients with Stage I to II head-and-neck cancer. Int J Radiat Oncol Biol Phys (2006) 1.02
Molecular bases of endometrial cancer: new roles for new actors in the diagnosis and the therapy of the disease. Mol Cell Endocrinol (2011) 1.01
Expression of Snail is associated with myofibroblast phenotype development in oral squamous cell carcinoma. Histochem Cell Biol (2009) 1.00
Proliferation and plasticity of human beta cells on physiologically occurring laminin isoforms. Mol Cell Endocrinol (2012) 1.00
Formation and activation of fibroblast spheroids depend on fibronectin-integrin interaction. Exp Cell Res (2008) 1.00
Epidermal growth factor receptor gene numerical aberrations are frequent events in actinic keratoses and invasive cutaneous squamous cell carcinomas. Exp Dermatol (2010) 0.99
A differential gene expression profile reveals overexpression of RUNX1/AML1 in invasive endometrioid carcinoma. Cancer Res (2004) 0.99
Distribution of laminins in the developing human eye. Invest Ophthalmol Vis Sci (2006) 0.98
Clonal proliferation of cyclin D1-positive mantle lymphocytes in an asymptomatic patient: an early-stage event in the development or an indolent form of a mantle cell lymphoma? Hum Pathol (2005) 0.98
A Phase II study of preoperative radiotherapy and concomitant weekly irinotecan in combination with protracted venous infusion 5-fluorouracil, for resectable locally advanced rectal cancer. Int J Radiat Oncol Biol Phys (2006) 0.96
Proteomic approach to ETV5 during endometrial carcinoma invasion reveals a link to oxidative stress. Carcinogenesis (2009) 0.95
Basement membrane protein distribution in LYVE-1-immunoreactive lymphatic vessels of normal tissues and ovarian carcinomas. Cell Tissue Res (2007) 0.95
Matrix metalloproteinase-2 and matrix metalloproteinase-9 codistribute with transcription factors RUNX1/AML1 and ETV5/ERM at the invasive front of endometrial and ovarian carcinoma. Hum Pathol (2010) 0.94
Nuclear expression of Snail1 in borderline and malignant epithelial ovarian tumours is associated with tumour progression. BMC Cancer (2009) 0.94
Localization of laminin alpha4-chain in developing and adult human tissues. J Histochem Cytochem (2002) 0.94
Epithelial-mesenchymal transition downregulates laminin alpha5 chain and upregulates laminin alpha4 chain in oral squamous carcinoma cells. Histochem Cell Biol (2008) 0.94
Oxidative stress triggers the amyloidogenic pathway in human vascular smooth muscle cells. Neurobiol Aging (2007) 0.94
HPV testing by cobas HPV test in a population from Catalonia. PLoS One (2013) 0.92
Laminin-511 expression is associated with the functionality of feeder cells in human embryonic stem cell culture. Stem Cell Res (2011) 0.92
Forkhead class O transcription factor 3a activation and Sirtuin1 overexpression in the hypertrophied myocardium of the diabetic Goto-Kakizaki rat. J Hypertens (2008) 0.92
Activation of the BMP4 pathway and early expression of CDX2 characterize non-specialized columnar metaplasia in a human model of Barrett's esophagus. J Gastrointest Surg (2011) 0.91
Disease-associated increased HIF-1, alphavbeta3 integrin, and Flt-1 do not suffice to compensate the damage-inducing loss of blood vessels in inflammatory myopathies. Rheumatol Int (2003) 0.90
An orthotopic endometrial cancer mouse model demonstrates a role for RUNX1 in distant metastasis. Int J Cancer (2009) 0.90
Laminin isoforms of lymph nodes and predominant role of alpha5-laminin(s) in adhesion and migration of blood lymphocytes. J Leukoc Biol (2008) 0.90
Upon Wnt stimulation, Rac1 activation requires Rac1 and Vav2 binding to p120-catenin. J Cell Sci (2012) 0.90
Nuclear ubiquitination by FBXL5 modulates Snail1 DNA binding and stability. Nucleic Acids Res (2013) 0.90
Acquired retinal astrocytoma managed with endoresection. Retina (2006) 0.89
Novel snail1 target proteins in human colon cancer identified by proteomic analysis. PLoS One (2010) 0.88
Segment-specific but pathologic laminin isoform profiles in human labial salivary glands of patients with Sjogren's syndrome. Arthritis Rheum (2004) 0.88
Angiotensin receptors in the eyes of arterial hypertensive rats. Acta Ophthalmol (2009) 0.88
Uncoordinated production of Laminin-5 chains in airways epithelium of allergic asthmatics. Respir Res (2005) 0.87
Incidence of human papillomavirus infection in male sexual partners of women diagnosed with CIN II-III. Eur J Dermatol (2012) 0.87
Laminin alpha-1, alpha-3, and alpha-5 chain expression in human prepubertal [correction of prepubetal] benign prostate glands and adult benign and malignant prostate glands. Prostate (2003) 0.87
CDC28 protein kinase regulatory subunit 1B (CKS1B) expression and genetic status analysis in oral squamous cell carcinoma. Histol Histopathol (2011) 0.87
Up-regulation of ERM/ETV5 correlates with the degree of myometrial infiltration in endometrioid endometrial carcinoma. J Pathol (2005) 0.86
ERM/ETV5 up-regulation plays a role during myometrial infiltration through matrix metalloproteinase-2 activation in endometrial cancer. Cancer Res (2007) 0.86
TFCP2c/LSF/LBP-1c is required for Snail1-induced fibronectin gene expression. Biochem J (2011) 0.85
Inhibition of specific NF-κB activity contributes to the tumor suppressor function of 14-3-3σ in breast cancer. PLoS One (2012) 0.85
Integrin alphavbeta3 binding to human alpha5-laminins facilitates FGF-2- and VEGF-induced proliferation of human ECV304 carcinoma cells. Eur J Cell Biol (2003) 0.84