Published in Nature on October 17, 1991
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Restoration of cytomegalovirus antigen presentation by gamma interferon combats viral escape. J Virol (1994) 1.71
Evidence for a role of immunoproteasomes in regulating cardiac muscle mass in diabetic mice. J Mol Cell Cardiol (2010) 1.61
Inhibition of hepatitis B virus replication by interferon requires proteasome activity. J Virol (2002) 1.58
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Coordinate regulation of the human TAP1 and LMP2 genes from a shared bidirectional promoter. J Exp Med (1995) 1.46
Allelic variants of the human putative peptide transporter involved in antigen processing. Proc Natl Acad Sci U S A (1992) 1.43
Changes in intracellular localization of proteasomes in immortalized ovarian granulosa cells during mitosis associated with a role in cell cycle control. Proc Natl Acad Sci U S A (1993) 1.30
Comparison of cell lines deficient in antigen presentation reveals a functional role for TAP-1 alone in antigen processing. J Exp Med (1994) 1.18
CD8+ T cell recognition of an endogenously processed epitope is regulated primarily by residues within the epitope. J Exp Med (1992) 1.17
Transcriptional re-programming of primary macrophages reveals distinct apoptotic and anti-tumoral functions of IRF-3 and IRF-7. Eur J Immunol (2009) 1.12
Processing of urushiol (poison ivy) hapten by both endogenous and exogenous pathways for presentation to T cells in vitro. J Clin Invest (1994) 1.00
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Characterization of an incompletely assembled major histocompatibility class I molecule (H-2Kb) associated with unusually long peptides: implications for antigen processing and presentation. Proc Natl Acad Sci U S A (1994) 0.95
Availability of endogenous peptides limits expression of an M3a-Ld major histocompatibility complex class I chimera. J Exp Med (1994) 0.91
Additive loss-of-function proteasome subunit mutations in CANDLE/PRAAS patients promote type I IFN production. J Clin Invest (2015) 0.90
Genomic polymorphism, recombination, and linkage disequilibrium in human major histocompatibility complex-encoded antigen-processing genes. Proc Natl Acad Sci U S A (1992) 0.90
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Processing of N3, a mammalian proteasome beta-type subunit. Biochem J (1996) 0.86
LMP-associated proteolytic activities and TAP-dependent peptide transport for class 1 MHC molecules are suppressed in cell lines transformed by the highly oncogenic adenovirus 12. J Exp Med (1996) 0.86
The requirement for proteasome activity class I major histocompatibility complex antigen presentation is dictated by the length of preprocessed antigen. J Exp Med (1996) 0.86
Antigen nonspecific effect of major histocompatibility complex haplotype on autoantibody levels in systemic lupus erythematosus-prone lpr mice. J Clin Invest (1993) 0.85
The alpha chain gene of H-2O has an unexpected location in the major histocompatibility complex. J Exp Med (1992) 0.85
Molecular basis of genetic polymorphism in major histocompatibility complex-linked proteasome gene (Lmp-2). Proc Natl Acad Sci U S A (1993) 0.84
Restrictions on the use of antigenic peptides by the immune system. Proc Natl Acad Sci U S A (1993) 0.84
Transcription of major histocompatibility complex class I (Kb) and transporter associated with antigen processing 1 and 2 genes is up-regulated with age. Immunology (2004) 0.83
mRNA expression profiling reveals a role of Helicobacter pylori vacuolating toxin in escaping host defense. World J Gastroenterol (2004) 0.79
The role of major histocompatibility complex molecules in luteal function. Reprod Biol Endocrinol (2003) 0.79
Clinical activity of carfilzomib correlates with inhibition of multiple proteasome subunits: application of a novel pharmacodynamic assay. Br J Haematol (2016) 0.78
Mouse chromosome 17. Mamm Genome (1992) 0.78
Cellular distribution of proteasome subunit Lmp7 mRNA and protein in human placentas. Immunology (1995) 0.78
Synthetic analogues of chymostatin. Inhibition of chymotrypsin and Streptomyces griseus proteinase A. Biochem J (1992) 0.76
Emerging role of immunoproteasomes in pathophysiology. Immunol Cell Biol (2016) 0.75
MHC-linked LMP gene products specifically alter peptidase activities of the proteasome. Nature (1993) 3.18
MHC class II region encoding proteins related to the multidrug resistance family of transmembrane transporters. Nature (1991) 2.94
Structural and serological similarity of MHC-linked LMP and proteasome (multicatalytic proteinase) complexes. Nature (1991) 2.56
An essential role for HLA-DM in antigen presentation by class II major histocompatibility molecules. Nature (1994) 2.41
Immunoproteasome assembly: cooperative incorporation of interferon gamma (IFN-gamma)-inducible subunits. J Exp Med (1998) 2.32
Ham-2 corrects the class I antigen-processing defect in RMA-S cells. Nature (1992) 2.27
Bacterioferritin A modulates catalase A (KatA) activity and resistance to hydrogen peroxide in Pseudomonas aeruginosa. J Bacteriol (1999) 2.09
A new human HLA class II-related locus, DM. Nature (1991) 1.91
Intermediates in the formation of mouse 20S proteasomes: implications for the assembly of precursor beta subunits. EMBO J (1997) 1.67
Identification of MECL-1 (LMP-10) as the third IFN-gamma-inducible proteasome subunit. J Immunol (1996) 1.62
The LMP antigens: a stable MHC-controlled multisubunit protein complex. Hum Immunol (1986) 1.28
Identification of a fourth class of proteins linked to the murine major histocompatibility complex. Proc Natl Acad Sci U S A (1982) 1.27
T cell recognition of QA-1b antigens on cells lacking a functional Tap-2 transporter. J Immunol (1992) 1.24
New class II-like genes in the murine MHC. Nature (1991) 1.20
H-2-linked low-molecular weight polypeptide antigens assemble into an unusual macromolecular complex. Nature (1984) 1.18
Activity and expression of the 20S proteasome are increased in skeletal muscle during sepsis. Am J Physiol (1999) 1.04
Identification of 40 genes on a 1-Mb contig around the IL-4 cytokine family gene cluster on mouse chromosome 11. Genomics (2000) 1.02
A cluster of transcribed sequences between the Pb and Ob genes of the murine major histocompatibility complex. Proc Natl Acad Sci U S A (1991) 0.97
Difference in antigen presentation pathways between cortical and medullary thymic epithelial cells. Eur J Immunol (1996) 0.96
Sequence and expression of mouse proteasome activator PA28 and the related autoantigen Ki. Immunogenetics (1997) 0.94
Identification of proteassemblin, a mammalian homologue of the yeast protein, Ump1p, that is required for normal proteasome assembly. Mol Cell Biol Res Commun (2000) 0.93
Molecular and serological analysis of polymorphisms in the murine major histocompatibility complex-encoded proteasome subunits, LMP-2 and LMP-7. Exp Clin Immunogenet (1996) 0.93
Genomic polymorphism, recombination, and linkage disequilibrium in human major histocompatibility complex-encoded antigen-processing genes. Proc Natl Acad Sci U S A (1992) 0.90
Expression of intra-MHC transporter (Ham) genes and class I antigens in diabetes-susceptible NOD mice. Science (1992) 0.89
The complete primary structure of mouse 20S proteasomes. Immunogenetics (1999) 0.89
LMP2 expression and proteasome activity in NOD mice. Nat Med (2000) 0.88
Burn injury upregulates the activity and gene expression of the 20 S proteasome in rat skeletal muscle. Clin Sci (Lond) (2000) 0.87
Delineation of the subunit composition of human proteasomes using antisera against the major histocompatibility complex-encoded LMP2 and LMP7 subunits. Proc Natl Acad Sci U S A (1994) 0.86
Post-translational processing of a major histocompatibility complex-encoded proteasome subunit, LMP-2. Mol Immunol (1993) 0.86
Antigen processing of two H2-IEd-restricted epitopes is differentially influenced by the structural changes in a viral glycoprotein. J Immunol (1998) 0.84
Class II antigen processing defects in two H2d mouse cell lines are caused by point mutations in the H2-DMa gene. Eur J Immunol (1999) 0.84
MHC-linked low-molecular mass polypeptide subunits define distinct subsets of proteasomes. Implications for divergent function among distinct proteasome subsets. J Immunol (1993) 0.84
Characterization of polymorphism within the H2-M MHC class II loci. Immunogenetics (1995) 0.83
Novel peptide-binding proteins and peptide transport in normal and TAP-deficient microsomes. Biochemistry (1997) 0.82
Sequence, linkage to H2-K, and function of mouse tapasin in MHC class I assembly. Immunogenetics (1998) 0.82
Genomic organization of the mouse Lmp-2 gene and characteristic structure of its promoter. Gene (1993) 0.81
Physical and functional association of the major histocompatibility complex class I heavy chain alpha3 domain with the transporter associated with antigen processing. J Exp Med (1998) 0.81
Allelic variation in the mouse Tap-1 and Tap-2 transporter genes. J Immunol (1997) 0.81
DNA sequence, chromosomal localization, and tissue expression of the mouse proteasome subunit lmp10 (Psmb10) gene. Genomics (1997) 0.78
Purification of 20S proteasomes. Methods Mol Biol (2001) 0.78
Biochemical purification of distinct proteasome subsets. Enzyme Protein (1993) 0.78
Interferon-gamma independently activates the MHC class I antigen processing pathway and diminishes glucose responsiveness in pancreatic beta-cell lines. Diabetes (1997) 0.78
Up-regulation of the proteasome subunit LMP7 in tissues of endotoxemic rats. J Lab Clin Med (2000) 0.78
Isolation and mapping of the rabbit DM genes. Immunogenetics (1999) 0.78
Cloning and characterization of mouse Lmp3 cDNA, encoding a proteasome beta subunit. Gene (1997) 0.77
RT1.DMa and RT1.DMb: the rat homologues of H2-DMa and H2-DMb. Immunogenetics (1995) 0.75
Peptide transport in antigen presentation. Curr Opin Hematol (1996) 0.75
How do endogenous proteins become peptides and reach the endoplasmic reticulum. Curr Top Microbiol Immunol (1998) 0.75
Characterization and mapping of the gene encoding mouse proteasome subunit DELTA (Lmp19). Immunogenetics (1995) 0.75
Production of congenic Anti-Lyt-3.1 sera. Immunogenetics (1978) 0.75