Published in Cell on June 30, 2006
Autophagy suppresses tumor progression by limiting chromosomal instability. Genes Dev (2007) 7.41
Comparative genomics and molecular dynamics of DNA repeats in eukaryotes. Microbiol Mol Biol Rev (2008) 3.35
Ohno's dilemma: evolution of new genes under continuous selection. Proc Natl Acad Sci U S A (2007) 3.10
Replication stalling at unstable inverted repeats: interplay between DNA hairpins and fork stabilizing proteins. Proc Natl Acad Sci U S A (2008) 2.23
Inverted DNA repeats channel repair of distant double-strand breaks into chromatid fusions and chromosomal rearrangements. Mol Cell Biol (2007) 1.75
Palindromic gene amplification--an evolutionarily conserved role for DNA inverted repeats in the genome. Nat Rev Cancer (2009) 1.62
Chromothripsis and beyond: rapid genome evolution from complex chromosomal rearrangements. Genes Dev (2013) 1.61
Dynamics and evolution of the inverted repeat-large single copy junctions in the chloroplast genomes of monocots. BMC Evol Biol (2008) 1.54
Defective break-induced replication leads to half-crossovers in Saccharomyces cerevisiae. Genetics (2008) 1.52
Telomere dysfunction and chromosome instability. Mutat Res (2011) 1.51
Nearby inverted repeats fuse to generate acentric and dicentric palindromic chromosomes by a replication template exchange mechanism. Genes Dev (2009) 1.50
Mre11-Sae2 and RPA Collaborate to Prevent Palindromic Gene Amplification. Mol Cell (2015) 1.48
Chromosome fragility at GAA tracts in yeast depends on repeat orientation and requires mismatch repair. EMBO J (2008) 1.40
Whole-genome sequencing of a laboratory-evolved yeast strain. BMC Genomics (2010) 1.34
Meiotic chromosome segregation in triploid strains of Saccharomyces cerevisiae. Genetics (2010) 1.33
Chromosomal inversions between human and chimpanzee lineages caused by retrotransposons. PLoS One (2008) 1.32
Chromosomal instability mediated by non-B DNA: cruciform conformation and not DNA sequence is responsible for recurrent translocation in humans. Genome Res (2008) 1.27
Fusion of nearby inverted repeats by a replication-based mechanism leads to formation of dicentric and acentric chromosomes that cause genome instability in budding yeast. Genes Dev (2009) 1.25
Amplification of a plasmid bearing a mammalian replication initiation region in chromosomal and extrachromosomal contexts. Nucleic Acids Res (2010) 1.16
A genetic and structural study of genome rearrangements mediated by high copy repeat Ty1 elements. PLoS Genet (2011) 1.11
Gene amplification: yeast takes a turn. Cell (2006) 1.10
Chromosome rearrangements and aneuploidy in yeast strains lacking both Tel1p and Mec1p reflect deficiencies in two different mechanisms. Proc Natl Acad Sci U S A (2010) 1.05
Origin-dependent inverted-repeat amplification: a replication-based model for generating palindromic amplicons. PLoS Genet (2011) 1.04
Models for chromosomal replication-independent non-B DNA structure-induced genetic instability. Mol Carcinog (2009) 1.02
Chromosomal imbalances in oral squamous cell carcinoma: examination of 31 cell lines and review of the literature. Oral Oncol (2007) 1.02
High rates of "unselected" aneuploidy and chromosome rearrangements in tel1 mec1 haploid yeast strains. Genetics (2008) 1.00
Gene copy-number variation in haploid and diploid strains of the yeast Saccharomyces cerevisiae. Genetics (2013) 0.98
Polyglutamine toxicity is controlled by prion composition and gene dosage in yeast. PLoS Genet (2012) 0.98
Stabilization of dicentric translocations through secondary rearrangements mediated by multiple mechanisms in S. cerevisiae. PLoS One (2009) 0.98
High-resolution mapping identifies a commonly amplified 11q13.3 region containing multiple genes flanked by segmental duplications. Hum Genet (2006) 0.98
Genome-wide stochastic adaptive DNA amplification at direct and inverted DNA repeats in the parasite Leishmania. PLoS Biol (2014) 0.96
E. coli SbcCD and RecA control chromosomal rearrangement induced by an interrupted palindrome. Mol Cell (2010) 0.96
DNA polymerases ζ and Rev1 mediate error-prone bypass of non-B DNA structures. Nucleic Acids Res (2013) 0.93
Multiple pathways of duplication formation with and without recombination (RecA) in Salmonella enterica. Genetics (2012) 0.92
Chronic oxidative DNA damage due to DNA repair defects causes chromosomal instability in Saccharomyces cerevisiae. Mol Cell Biol (2008) 0.92
Large inverted duplications in the human genome form via a fold-back mechanism. PLoS Genet (2014) 0.91
Single-stranded annealing induced by re-initiation of replication origins provides a novel and efficient mechanism for generating copy number expansion via non-allelic homologous recombination. PLoS Genet (2013) 0.91
Chromosome aberrations resulting from double-strand DNA breaks at a naturally occurring yeast fragile site composed of inverted ty elements are independent of Mre11p and Sae2p. Genetics (2009) 0.89
Natural diversity in flowering responses of Arabidopsis thaliana caused by variation in a tandem gene array. Genetics (2010) 0.88
Assessment of palindromes as platforms for DNA amplification in breast cancer. Genome Res (2011) 0.88
Leaping forks at inverted repeats. Genes Dev (2010) 0.88
The sister chromatid cohesion pathway suppresses multiple chromosome gain and chromosome amplification. Genetics (2013) 0.87
Break-induced replication and genome stability. Biomolecules (2012) 0.87
Tandem repeats and G-rich sequences are enriched at human CNV breakpoints. PLoS One (2014) 0.86
Multiple cellular mechanisms prevent chromosomal rearrangements involving repetitive DNA. Crit Rev Biochem Mol Biol (2012) 0.86
Episomal high copy number maintenance of hairpin-capped DNA bearing a replication initiation region in human cells. J Biol Chem (2009) 0.85
Homology-mediated end-capping as a primary step of sister chromatid fusion in the breakage-fusion-bridge cycles. Nucleic Acids Res (2013) 0.85
A common copy-number breakpoint of ERBB2 amplification in breast cancer colocalizes with a complex block of segmental duplications. Breast Cancer Res (2012) 0.84
Real-time detection of cruciform extrusion by single-molecule DNA nanomanipulation. Nucleic Acids Res (2011) 0.83
Nonrandom distribution of interhomolog recombination events induced by breakage of a dicentric chromosome in Saccharomyces cerevisiae. Genetics (2013) 0.83
Centrosome clustering and cyclin D1 gene amplification in double minutes are common events in chromosomal unstable bladder tumors. BMC Cancer (2010) 0.82
Rapid analysis of Saccharomyces cerevisiae genome rearrangements by multiplex ligation-dependent probe amplification. PLoS Genet (2012) 0.82
Back to the origin: reconsidering replication, transcription, epigenetics, and cell cycle control. Genes Cancer (2012) 0.82
A mechanism of gene amplification driven by small DNA fragments. PLoS Genet (2012) 0.81
Chromosome breakage and repair. Genetics (2006) 0.81
Large inverted repeats within Xp11.2 are present at the breakpoints of isodicentric X chromosomes in Turner syndrome. Hum Mol Genet (2010) 0.81
Fragile DNA motifs trigger mutagenesis at distant chromosomal loci in saccharomyces cerevisiae. PLoS Genet (2013) 0.80
De novo-generated small palindromes are characteristic of amplicon boundary junction of double minutes. Int J Cancer (2013) 0.80
Effects of mutations in SGS1 and in genes functionally related to SGS1 on inverted repeat-stimulated spontaneous unequal sister-chromatid exchange in yeast. BMC Mol Biol (2007) 0.79
Molecular organization of the 25S-18S rDNA IGS of Fagus sylvatica and Quercus suber: a comparative analysis. PLoS One (2014) 0.79
Cloning and Characterization of a Human Genomic Sequence that Alleviates Repeat-Induced Gene Silencing. PLoS One (2016) 0.79
Yap1: a DNA damage responder in Saccharomyces cerevisiae. Mech Ageing Dev (2012) 0.78
Genome-wide screen reveals replication pathway for quasi-palindrome fragility dependent on homologous recombination. PLoS Genet (2013) 0.78
Suppression of allelic recombination and aneuploidy by cohesin is independent of Chk1 in Saccharomyces cerevisiae. PLoS One (2014) 0.78
Genetic and epigenetic instability of amplification-prone sequences of a novel B chromosome induced by tissue culture in Plantago lagopus L. Plant Cell Rep (2009) 0.78
The role of replication bypass pathways in dicentric chromosome formation in budding yeast. Genetics (2010) 0.77
Replication fork integrity and intra-S phase checkpoint suppress gene amplification. Nucleic Acids Res (2015) 0.77
Palindromic amplification of the ERBB2 oncogene in primary HER2-positive breast tumors. Sci Rep (2017) 0.75
Met promotes the formation of double minute chromosomes induced by Sei-1 in NIH-3T3 murine fibroblasts. Oncotarget (2016) 0.75
Ancient intron insertion sites and palindromic genomic duplication evolutionally shapes an elementally functioning membrane protein family. BMC Evol Biol (2007) 0.75
Break-induced replication: an unhealthy choice for stress relief? Nat Struct Mol Biol (2017) 0.75
Amplification of a transgene within a long array of replication origins favors higher gene expression in animal cells. PLoS One (2017) 0.75
Analyzing Genome Rearrangements in Saccharomyces cerevisiae. Methods Mol Biol (2018) 0.75
Pathways and Mechanisms that Prevent Genome Instability in Saccharomyces cerevisiae. Genetics (2017) 0.75
Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. N Engl J Med (2015) 5.71
Clustered mutations in yeast and in human cancers can arise from damaged long single-strand DNA regions. Mol Cell (2012) 4.52
Chromosomal translocations in yeast induced by low levels of DNA polymerase a model for chromosome fragile sites. Cell (2005) 3.74
Genetic heterogeneity of diffuse large B-cell lymphoma. Proc Natl Acad Sci U S A (2013) 3.25
Novel bioactive materials with different mechanical properties. Biomaterials (2003) 3.16
Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma. N Engl J Med (2015) 3.00
Double-strand breaks associated with repetitive DNA can reshape the genome. Proc Natl Acad Sci U S A (2008) 2.28
Replication stalling at unstable inverted repeats: interplay between DNA hairpins and fork stabilizing proteins. Proc Natl Acad Sci U S A (2008) 2.23
Evidence for an ancient adaptive episode of convergent molecular evolution. Proc Natl Acad Sci U S A (2009) 2.14
Genome structure of a Saccharomyces cerevisiae strain widely used in bioethanol production. Genome Res (2009) 1.94
Preparation and assessment of revised simulated body fluids. J Biomed Mater Res A (2003) 1.93
Inositol diphosphate signaling regulates telomere length. J Biol Chem (2004) 1.85
Structural dependence of apatite formation on titania gels in a simulated body fluid. J Biomed Mater Res A (2003) 1.84
Inverted DNA repeats channel repair of distant double-strand breaks into chromatid fusions and chromosomal rearrangements. Mol Cell Biol (2007) 1.75
MAP3K4/CBP-regulated H2B acetylation controls epithelial-mesenchymal transition in trophoblast stem cells. Cell Stem Cell (2011) 1.71
Variation in efficiency of DNA mismatch repair at different sites in the yeast genome. Proc Natl Acad Sci U S A (2005) 1.71
Recombination between retrotransposons as a source of chromosome rearrangements in the yeast Saccharomyces cerevisiae. DNA Repair (Amst) (2006) 1.67
Migrating bubble during break-induced replication drives conservative DNA synthesis. Nature (2013) 1.66
Osteoinduction of porous bioactive titanium metal. Biomaterials (2004) 1.61
A fine-structure map of spontaneous mitotic crossovers in the yeast Saccharomyces cerevisiae. PLoS Genet (2009) 1.61
Preparation of bioactive titanium metal via anodic oxidation treatment. Biomaterials (2004) 1.53
Large-scale expansions of Friedreich's ataxia GAA repeats in yeast. Mol Cell (2009) 1.52
Regulation of genome stability by TEL1 and MEC1, yeast homologs of the mammalian ATM and ATR genes. Genetics (2002) 1.51
Selection and analysis of spontaneous reciprocal mitotic cross-overs in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2006) 1.47
Loss of a histone deacetylase dramatically alters the genomic distribution of Spo11p-catalyzed DNA breaks in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2007) 1.46
Decreased muscle loading delays maturation of the tendon enthesis during postnatal development. J Orthop Res (2007) 1.44
Chromosome fragility at GAA tracts in yeast depends on repeat orientation and requires mismatch repair. EMBO J (2008) 1.40
Factors affecting healing rates after arthroscopic double-row rotator cuff repair. Am J Sports Med (2010) 1.39
The histone methylase Set2p and the histone deacetylase Rpd3p repress meiotic recombination at the HIS4 meiotic recombination hotspot in Saccharomyces cerevisiae. DNA Repair (Amst) (2008) 1.38
Genetic regulation of telomere-telomere fusions in the yeast Saccharomyces cerevisae. Proc Natl Acad Sci U S A (2003) 1.37
Genome-wide model for the normal eukaryotic DNA replication fork. Proc Natl Acad Sci U S A (2010) 1.36
Patterns of heteroduplex formation associated with the initiation of meiotic recombination in the yeast Saccharomyces cerevisiae. Genetics (2003) 1.36
Meiotic chromosome segregation in triploid strains of Saccharomyces cerevisiae. Genetics (2010) 1.33
Global analysis of the relationship between the binding of the Bas1p transcription factor and meiosis-specific double-strand DNA breaks in Saccharomyces cerevisiae. Mol Cell Biol (2006) 1.33
High-resolution genome-wide analysis of irradiated (UV and γ-rays) diploid yeast cells reveals a high frequency of genomic loss of heterozygosity (LOH) events. Genetics (2012) 1.19
From the Cover: mitotic gene conversion events induced in G1-synchronized yeast cells by gamma rays are similar to spontaneous conversion events. Proc Natl Acad Sci U S A (2010) 1.14
A comparative study between in vivo bone ingrowth and in vitro apatite formation on Na2O-CaO-SiO2 glasses. Biomaterials (2003) 1.13
High-resolution mapping of spontaneous mitotic recombination hotspots on the 1.1 Mb arm of yeast chromosome IV. PLoS Genet (2013) 1.12
Mechanism of bonelike apatite formation on bioactive tantalum metal in a simulated body fluid. Biomaterials (2002) 1.12
Apatite formation on zirconium metal treated with aqueous NaOH. Biomaterials (2002) 1.11
The compact chromatin structure of a Ty repeated sequence suppresses recombination hotspot activity in Saccharomyces cerevisiae. Mol Cell (2004) 1.08
Caenorhabditis elegans DNA mismatch repair gene msh-2 is required for microsatellite stability and maintenance of genome integrity. Proc Natl Acad Sci U S A (2002) 1.08
Interplay between structure-specific endonucleases for crossover control during Caenorhabditis elegans meiosis. PLoS Genet (2013) 1.07
Friedreich's ataxia (GAA)n•(TTC)n repeats strongly stimulate mitotic crossovers in Saccharomyces cerevisae. PLoS Genet (2011) 1.06
Reduced levels of DNA polymerase delta induce chromosome fragile site instability in yeast. Mol Cell Biol (2008) 1.06
Preparation of antibacterial silver-doped silica glass microspheres. J Biomed Mater Res A (2003) 1.06
Damage-induced localized hypermutability. Cell Cycle (2011) 1.05
Chromosome rearrangements and aneuploidy in yeast strains lacking both Tel1p and Mec1p reflect deficiencies in two different mechanisms. Proc Natl Acad Sci U S A (2010) 1.05
Detecting ultraviolet damage in single DNA molecules by atomic force microscopy. Biophys J (2007) 1.05
Genome-wide high-resolution mapping of UV-induced mitotic recombination events in Saccharomyces cerevisiae. PLoS Genet (2013) 1.04
Biology of alkali- and heat-treated titanium implants. J Biomed Mater Res A (2003) 1.04
Tup1 stabilizes promoter nucleosome positioning and occupancy at transcriptionally plastic genes. Nucleic Acids Res (2011) 1.04
Effect of water treatment on the apatite-forming ability of NaOH-treated titanium metal. J Biomed Mater Res (2002) 1.02
Apatite-forming ability of a zirconia/alumina nano-composite induced by chemical treatment. J Biomed Mater Res (2002) 1.02
Low levels of DNA polymerase alpha induce mitotic and meiotic instability in the ribosomal DNA gene cluster of Saccharomyces cerevisiae. PLoS Genet (2008) 1.00
Amino acid changes in Xrs2p, Dun1p, and Rfa2p that remove the preferred targets of the ATM family of protein kinases do not affect DNA repair or telomere length in Saccharomyces cerevisiae. DNA Repair (Amst) (2003) 1.00
High rates of "unselected" aneuploidy and chromosome rearrangements in tel1 mec1 haploid yeast strains. Genetics (2008) 1.00
Gene copy-number variation in haploid and diploid strains of the yeast Saccharomyces cerevisiae. Genetics (2013) 0.98
Alleles of the yeast Pms1 mismatch-repair gene that differentially affect recombination- and replication-related processes. Genetics (2002) 0.97
Formation and growth of clusters in conventional and new kinds of simulated body fluids. J Biomed Mater Res A (2003) 0.96
Reconstructing genome evolution in historic samples of the Irish potato famine pathogen. Nat Commun (2013) 0.95
Chromatin architectures at fission yeast transcriptional promoters and replication origins. Nucleic Acids Res (2012) 0.95
Analysis of the proteins involved in the in vivo repair of base-base mismatches and four-base loops formed during meiotic recombination in the yeast Saccharomyces cerevisiae. Genetics (2006) 0.94
Surface modification of hydroxyapatite nanocrystals by grafting polymers containing phosphonic acid groups. J Colloid Interface Sci (2006) 0.94
Modulation of mutagenesis in eukaryotes by DNA replication fork dynamics and quality of nucleotide pools. Environ Mol Mutagen (2012) 0.93
Genome-wide screen identifies pathways that govern GAA/TTC repeat fragility and expansions in dividing and nondividing yeast cells. Mol Cell (2012) 0.92
Chronic oxidative DNA damage due to DNA repair defects causes chromosomal instability in Saccharomyces cerevisiae. Mol Cell Biol (2008) 0.92
Role of proliferating cell nuclear antigen interactions in the mismatch repair-dependent processing of mitotic and meiotic recombination intermediates in yeast. Genetics (2008) 0.91
Genome rearrangements caused by interstitial telomeric sequences in yeast. Proc Natl Acad Sci U S A (2013) 0.91
Intrachromosomal gene amplification triggered by hairpin-capped breaks requires homologous recombination and is independent of nonhomologous end-joining. Cell Cycle (2007) 0.90
UVA generates pyrimidine dimers in DNA directly. Biophys J (2009) 0.90
A reversible histone H3 acetylation cooperates with mismatch repair and replicative polymerases in maintaining genome stability. PLoS Genet (2013) 0.89
Chromosome aberrations resulting from double-strand DNA breaks at a naturally occurring yeast fragile site composed of inverted ty elements are independent of Mre11p and Sae2p. Genetics (2009) 0.89
Variant calling in low-coverage whole genome sequencing of a Native American population sample. BMC Genomics (2014) 0.88
Effect of hot water and heat treatment on the apatite-forming ability of titania films formed on titanium metal via anodic oxidation in acetic acid solutions. J Mater Sci Mater Med (2007) 0.88
Histological and mechanical investigation of the bone-bonding ability of anodically oxidized titanium in rabbits. Biomaterials (2003) 0.86
Repair of segmental long bone defect in rabbit femur using bioactive titanium cylindrical mesh cage. Biomaterials (2003) 0.85
ifet-1 is a broad-scale translational repressor required for normal P granule formation in C. elegans. J Cell Sci (2012) 0.85
Associations between cardio-ankle vascular index and microvascular complications in type 2 diabetes mellitus patients. J Atheroscler Thromb (2011) 0.84
Genomic deletions and point mutations induced in Saccharomyces cerevisiae by the trinucleotide repeats (GAA·TTC) associated with Friedreich's ataxia. DNA Repair (Amst) (2012) 0.83
Nonrandom distribution of interhomolog recombination events induced by breakage of a dicentric chromosome in Saccharomyces cerevisiae. Genetics (2013) 0.83
Nanoscale detection of ionizing radiation damage to DNA by atomic force microscopy. Small (2008) 0.81
Haploidization in Saccharomyces cerevisiae induced by a deficiency in homologous recombination. Genetics (2012) 0.80
When secondary comes first--the importance of non-canonical DNA structures. Biochimie (2012) 0.80
Fragile DNA motifs trigger mutagenesis at distant chromosomal loci in saccharomyces cerevisiae. PLoS Genet (2013) 0.80
Thromboresistance of alkali- and heat-treated titanium metal formed with apatite. J Biomed Mater Res A (2003) 0.79
Long-term retrospective study of narrow implants for fixed dental prostheses. Clin Oral Implants Res (2012) 0.79
Reciprocal uniparental disomy in yeast. Proc Natl Acad Sci U S A (2012) 0.79