Published in N Engl J Med on July 06, 2006
Nighttime intensivist staffing and mortality among critically ill patients. N Engl J Med (2012) 5.22
The effect of multidisciplinary care teams on intensive care unit mortality. Arch Intern Med (2010) 4.41
Long-term acute care hospital utilization after critical illness. JAMA (2010) 3.99
Comparative Effectiveness of Noninvasive and Invasive Ventilation in Critically Ill Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease. Crit Care Med (2015) 3.37
The Association Between Daytime Intensivist Physician Staffing and Mortality in the Context of Other ICU Organizational Practices: A Multicenter Cohort Study. Crit Care Med (2015) 2.71
Prediction of critical illness during out-of-hospital emergency care. JAMA (2010) 2.60
Frequency, cost, and risk factors of readmissions among severe sepsis survivors. Crit Care Med (2015) 2.50
Is survival better at hospitals with higher "end-of-life" treatment intensity? Med Care (2010) 2.35
A systematic review to inform institutional decisions about the use of extracorporeal membrane oxygenation during the H1N1 influenza pandemic. Crit Care Med (2010) 2.25
The effect of insurance status on mortality and procedural use in critically ill patients. Am J Respir Crit Care Med (2011) 2.03
Intensive care unit occupancy and patient outcomes. Crit Care Med (2009) 1.87
ICU occupancy and mechanical ventilator use in the United States. Crit Care Med (2013) 1.87
The effects of trauma center care, admission volume, and surgical volume on paralysis after traumatic spinal cord injury. Ann Surg (2009) 1.86
The structure of critical care transfer networks. Med Care (2009) 1.72
Objective factors associated with physicians' and nurses' perceptions of intensive care unit capacity strain. Ann Am Thorac Soc (2014) 1.68
Association of hospital-level volume of extracorporeal membrane oxygenation cases and mortality. Analysis of the extracorporeal life support organization registry. Am J Respir Crit Care Med (2015) 1.67
Relation between volume and outcome for patients with severe sepsis in United Kingdom: retrospective cohort study. BMJ (2012) 1.64
The relationship between hospital volume and mortality in mechanical ventilation: an instrumental variable analysis. Health Serv Res (2009) 1.63
Impact of critical care nursing on 30-day mortality of mechanically ventilated older adults. Crit Care Med (2014) 1.60
Effect of intensive care unit organizational model and structure on outcomes in patients with acute lung injury. Am J Respir Crit Care Med (2007) 1.58
Differences in critical care practice between an industrialized and a developing country. Wien Klin Wochenschr (2008) 1.52
Structure, process, and annual ICU mortality across 69 centers: United States Critical Illness and Injury Trials Group Critical Illness Outcomes Study. Crit Care Med (2014) 1.48
Potential value of regionalized intensive care for mechanically ventilated medical patients. Am J Respir Crit Care Med (2007) 1.47
Using existing data to address important clinical questions in critical care. Crit Care Med (2013) 1.47
Effectiveness of long-term acute care hospitalization in elderly patients with chronic critical illness. Med Care (2013) 1.46
Patient volume affects outcome in critically ill patients. Wien Klin Wochenschr (2009) 1.45
Patterns of depressive symptoms in caregivers of mechanically ventilated critically ill adults from intensive care unit admission to 2 months postintensive care unit discharge: a pilot study. Crit Care Med (2012) 1.45
The influence of volume and intensive care unit organization on hospital mortality in patients admitted with severe sepsis: a retrospective multicentre cohort study. Crit Care (2007) 1.43
The association between comorbid illness, colonization status, and acute hospitalization in patients receiving prolonged mechanical ventilation. Respir Care (2013) 1.41
Uncharted paths: hospital networks in critical care. Chest (2009) 1.37
Hospital case volume and outcomes among patients hospitalized with severe sepsis. Am J Respir Crit Care Med (2014) 1.23
Prolonged acute mechanical ventilation and hospital bed utilization in 2020 in the United States: implications for budgets, plant and personnel planning. BMC Health Serv Res (2008) 1.23
Chronic kidney disease and risk of death from infection. Am J Nephrol (2011) 1.17
Nighttime intensivist staffing and the timing of death among ICU decedents: a retrospective cohort study. Crit Care (2013) 1.15
Decision making in interhospital transport of critically ill patients: national questionnaire survey among critical care physicians. Intensive Care Med (2008) 1.13
Nurse practitioner/physician assistant staffing and critical care mortality. Chest (2014) 1.00
Bench-to-bedside review: the evaluation of complex interventions in critical care. Crit Care (2008) 1.00
Pro/con debate: do the benefits of regionalized critical care delivery outweigh the risks of interfacility patient transport? Crit Care (2009) 0.99
Volume, outcome, and the organization of intensive care. Crit Care (2007) 0.99
Statewide costs of health care-associated infections: estimates for acute care hospitals in North Carolina. Am J Infect Control (2013) 0.97
The Volume-Outcome Relationship in Critical Care: A Systematic Review and Meta-analysis. Chest (2015) 0.97
Trauma triage in the emergency departments of nontrauma centers: an analysis of individual physician caseload on triage patterns. J Trauma Acute Care Surg (2013) 0.94
Critical Illness Outcome Study: An Observational Study on Protocols and Mortality in Intensive Care Units. Open Access J Clin Trials (2011) 0.92
Should we regionalize the management of pulmonary embolism? CMAJ (2008) 0.91
Hospital-level factors associated with report of physical activity in patients on mechanical ventilation across Washington State. Ann Am Thorac Soc (2015) 0.89
PICU Volume and Outcome: A Severity-Adjusted Analysis. Pediatr Crit Care Med (2016) 0.88
Reasons underlying interhospital transfers to an academic medical intensive care unit. J Crit Care (2012) 0.88
Adoption of ICU telemedicine in the United States. Crit Care Med (2014) 0.88
The epidemiology of ventilator-associated pneumonia in a network of community hospitals: a prospective multicenter study. Infect Control Hosp Epidemiol (2013) 0.88
County-Level Effects of Prehospital Regionalization of Critically Ill Patients: A Simulation Study. Crit Care Med (2015) 0.87
Extracorporeal life support for pandemic influenza: the role of extracorporeal membrane oxygenation in pandemic management. J Extra Corpor Technol (2010) 0.86
Characteristics of mechanical ventilation employed in intensive care units: a multicenter survey of hospitals. J Korean Med Sci (2008) 0.86
Self-reported physical symptoms in intensive care unit (ICU) survivors: pilot exploration over four months post-ICU discharge. J Pain Symptom Manage (2013) 0.85
Economics of ICU organization and management. Crit Care Clin (2011) 0.84
Hospital volume and patient outcomes in pulmonary embolism. CMAJ (2008) 0.84
Predictors of early postdischarge mortality in critically ill patients: a retrospective cohort study from the California Intensive Care Outcomes project. J Crit Care (2010) 0.84
Mortality and denial of admission to an intensive care unit. Am J Respir Crit Care Med (2012) 0.84
Nurses versus physician-led interhospital critical care transport: a randomized non-inferiority trial. Intensive Care Med (2016) 0.84
The influence of hospitalization or intensive care unit admission on declines in health-related quality of life. Ann Am Thorac Soc (2015) 0.83
Variation in critical care unit admission rates and outcomes for patients with acute coronary syndromes or heart failure among high- and low-volume cardiac hospitals. J Am Heart Assoc (2015) 0.82
Association between hospital volume and network membership and an analgesia, sedation and delirium order set quality score: a cohort study. Crit Care (2012) 0.82
Global burden of influenza as a cause of cardiopulmonary morbidity and mortality. Glob Heart (2014) 0.82
Comparing mortality among adult, general intensive care units in England with varying intensivist cover patterns: a retrospective cohort study. Crit Care (2014) 0.82
Surge capacity: analysis of census fluctuations to estimate the number of intensive care unit beds needed. Health Serv Res (2014) 0.81
Perceived barriers to the regionalization of adult critical care in the United States: a qualitative preliminary study. BMC Health Serv Res (2008) 0.81
Ave, CESAR, morituri te salutant! (Hail, CESAR, those who are about to die salute you!). Crit Care (2010) 0.80
Decreased mortality resulting from a multicomponent intervention in a tertiary care medical intensive care unit. Crit Care Med (2011) 0.79
Variability of structures in German intensive care units--a representative, nationwide analysis. Wien Klin Wochenschr (2010) 0.79
Global analysis of critical care burden. Lancet Respir Med (2014) 0.79
Geographic access to high capability severe acute respiratory failure centers in the United States. PLoS One (2014) 0.78
Difficult airway management resources and capnography use in Japanese intensive care units: a nationwide cross-sectional study. J Anesth (2016) 0.78
Effect of cardiogenic shock hospital volume on mortality in patients with cardiogenic shock. J Am Heart Assoc (2015) 0.77
The effect of hospital volume on mortality in patients admitted with severe sepsis. PLoS One (2014) 0.77
Volume-Mortality Relationships during Hospitalization with Severe Sepsis Exist Only at Low Case Volumes. Ann Am Thorac Soc (2015) 0.76
Risk Factors for In-Hospital Mortality in Smoke Inhalation-Associated Acute Lung Injury: Data From 68 United States Hospitals. Chest (2016) 0.76
The prediction accuracy of dynamic mixed-effects models in clustered data. BioData Min (2016) 0.76
The essential nature of healthcare databases in critical care medicine. Crit Care (2008) 0.75
Association Between Vitamin D Status and Weaning From Prolonged Mechanical Ventilation in Survivors of Critical Illness. Respir Care (2015) 0.75
Association between treatment at an ST-segment elevation myocardial infarction center and neurologic recovery after out-of-hospital cardiac arrest. Am Heart J (2015) 0.75
Year in review 2006: Critical Care--Respirology. Crit Care (2007) 0.75
Fixed effects modelling for provider mortality outcomes: Analysis of the Australia and New Zealand Intensive Care Society (ANZICS) Adult Patient Data-base. PLoS One (2014) 0.75
A Comparison of Free-Standing versus Co-Located Long-Term Acute Care Hospitals. PLoS One (2015) 0.75
Implementation of a guideline for the treatment of pain, sedation, agitation and neuromuscular blockade in the mechanically ventilated adult patient in the emergency department. Open Access Emerg Med (2011) 0.75
Hospital volume and outcomes of mechanical ventilation. N Engl J Med (2006) 0.75
ICU Telemedicine and Critical Care Mortality: A National Effectiveness Study. Med Care (2016) 0.75
Hospital volume and outcomes of mechanical ventilation. N Engl J Med (2006) 0.75
Recently published papers: delivery, volume and outcome--what is best for our patient? Crit Care (2007) 0.75
External validation of a prehospital risk score for critical illness. Crit Care (2016) 0.75
Recently published papers: pneumonia, hypothermia and the elderly. Crit Care (2006) 0.75
Year in review 2007: Critical Care--intensive care unit management. Crit Care (2008) 0.75
[Volume theory--volume void?!]. Wien Klin Wochenschr (2009) 0.75
Multicenter study on the prognosis associated with respiratory support for children with acute hypoxic respiratory failure. Exp Ther Med (2016) 0.75
Telemedicine with clinical decision support for critical care: a systematic review. Syst Rev (2016) 0.75
Regionalized Critical Care May Be Feasible, But Will It Improve Outcomes? Crit Care Med (2015) 0.75
Impact of chlorhexidine mouthwash prophylaxis on probable ventilator-associated pneumonia in a surgical intensive care unit. Int J Crit Illn Inj Sci (2016) 0.75
Development and evaluation of an appraisal form to assess clinical effectiveness of adult invasive mechanical ventilation systems. Scand J Trauma Resusc Emerg Med (2012) 0.75
Mechanical ventilation and clinical practice heterogeneity in intensive care units: a multicenter case-vignette study. Ann Intensive Care (2014) 0.75
Hospital Volume and Outcomes of Noninvasive Ventilation in Patients Hospitalized With an Acute Exacerbation of Chronic Obstructive Pulmonary Disease. Crit Care Med (2016) 0.75
Research priorities for administrative challenges of integrated networks of care. Acad Emerg Med (2010) 0.75
Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012. Crit Care Med (2013) 39.56
Acute respiratory distress syndrome: the Berlin Definition. JAMA (2012) 21.04
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012. Intensive Care Med (2013) 17.37
Release from prison--a high risk of death for former inmates. N Engl J Med (2007) 12.46
A randomized trial of vertebroplasty for osteoporotic spinal fractures. N Engl J Med (2009) 10.06
Use of intensive care at the end of life in the United States: an epidemiologic study. Crit Care Med (2004) 9.06
Acute Physiology and Chronic Health Evaluation (APACHE) IV: hospital mortality assessment for today's critically ill patients. Crit Care Med (2006) 6.79
Critical care and the global burden of critical illness in adults. Lancet (2010) 5.55
Nighttime intensivist staffing and mortality among critically ill patients. N Engl J Med (2012) 5.22
A randomized trial of epidural glucocorticoid injections for spinal stenosis. N Engl J Med (2014) 5.01
Critical care's great leap forward? Crit Care Med (2006) 4.90
Temporal trends in the prevalence of diabetic kidney disease in the United States. JAMA (2011) 4.70
Cystic fibrosis pulmonary guidelines: chronic medications for maintenance of lung health. Am J Respir Crit Care Med (2007) 4.34
Cytomegalovirus reactivation in critically ill immunocompetent patients. JAMA (2008) 4.19
Surgery versus non-surgical therapy for carpal tunnel syndrome: a randomised parallel-group trial. Lancet (2009) 4.05
Recommendations for end-of-life care in the intensive care unit: a consensus statement by the American College [corrected] of Critical Care Medicine. Crit Care Med (2008) 3.85
Effectiveness of vertebroplasty using individual patient data from two randomised placebo controlled trials: meta-analysis. BMJ (2011) 3.69
Sexual risk, nitrite inhalant use, and lack of circumcision associated with HIV seroconversion in men who have sex with men in the United States. J Acquir Immune Defic Syndr (2005) 3.54
The myth of the workforce crisis. Why the United States does not need more intensivist physicians. Am J Respir Crit Care Med (2015) 3.43
Missed opportunities during family conferences about end-of-life care in the intensive care unit. Am J Respir Crit Care Med (2005) 3.40
Barriers to implementing protocol-based sepsis resuscitation in the emergency department--results of a national survey. Crit Care Med (2007) 3.28
The Berlin definition of ARDS: an expanded rationale, justification, and supplementary material. Intensive Care Med (2012) 3.18
Family satisfaction with family conferences about end-of-life care in the intensive care unit: increased proportion of family speech is associated with increased satisfaction. Crit Care Med (2004) 3.18
Clinician statements and family satisfaction with family conferences in the intensive care unit. Crit Care Med (2006) 3.08
Effect of a quality-improvement intervention on end-of-life care in the intensive care unit: a randomized trial. Am J Respir Crit Care Med (2010) 2.94
Incidence of acute lung injury in the United States. Crit Care Med (2003) 2.93
Assessing contemporary intensive care unit outcome: an updated Mortality Probability Admission Model (MPM0-III). Crit Care Med (2007) 2.91
Effect of therapeutic footwear on foot reulceration in patients with diabetes: a randomized controlled trial. JAMA (2002) 2.91
An Official ATS/AACN/ACCP/ESICM/SCCM Policy Statement: Responding to Requests for Potentially Inappropriate Treatments in Intensive Care Units. Am J Respir Crit Care Med (2015) 2.86
The burden of influenza-associated critical illness hospitalizations. Crit Care Med (2014) 2.84
Effect of azithromycin on pulmonary function in patients with cystic fibrosis uninfected with Pseudomonas aeruginosa: a randomized controlled trial. JAMA (2010) 2.75
Causes and timing of death in patients with ARDS. Chest (2005) 2.72
Comparison of the Full Outline of UnResponsiveness score and the Glasgow Coma Scale in predicting mortality in critically ill patients*. Crit Care Med (2015) 2.68
Cystic fibrosis pulmonary guidelines: treatment of pulmonary exacerbations. Am J Respir Crit Care Med (2009) 2.65
Do intensivist staffing patterns influence hospital mortality following ICU admission? A systematic review and meta-analyses. Crit Care Med (2013) 2.64
A comparison between audio computer-assisted self-interviews and clinician interviews for obtaining the sexual history. Sex Transm Dis (2004) 2.62
Regression analysis of longitudinal binary data with time-dependent environmental covariates: bias and efficiency. Biostatistics (2005) 2.60
Developing cystic fibrosis lung transplant referral criteria using predictors of 2-year mortality. Am J Respir Crit Care Med (2002) 2.50
Potential confounding by exposure history and prior outcomes: an example from perinatal epidemiology. Epidemiology (2007) 2.45
Prioritizing the organization and management of intensive care services in the United States: the PrOMIS Conference. Crit Care Med (2007) 2.42
Evaluation of a standardized order form for the withdrawal of life support in the intensive care unit. Crit Care Med (2004) 2.42
Failure to recover to baseline pulmonary function after cystic fibrosis pulmonary exacerbation. Am J Respir Crit Care Med (2010) 2.40
Beyond mortality: future clinical research in acute lung injury. Am J Respir Crit Care Med (2010) 2.28
Apolipoprotein E genotype and neurodevelopmental sequelae of infant cardiac surgery. J Thorac Cardiovasc Surg (2003) 2.25
Monitoring influenza activity in the United States: a comparison of traditional surveillance systems with Google Flu Trends. PLoS One (2011) 2.21
Elevated prevalence of hepatitis C infection in users of United States veterans medical centers. Hepatology (2005) 2.21
Longevity of patients with cystic fibrosis in 2000 to 2010 and beyond: survival analysis of the Cystic Fibrosis Foundation patient registry. Ann Intern Med (2014) 2.15
Directly parameterized regression conditioning on being alive: analysis of longitudinal data truncated by deaths. Biostatistics (2005) 2.15
Disease-specific reference equations for lung function in patients with cystic fibrosis. Am J Respir Crit Care Med (2005) 2.13
Prediction of diabetic foot ulcer occurrence using commonly available clinical information: the Seattle Diabetic Foot Study. Diabetes Care (2006) 2.13
Population-based trends in volumes and rates of ambulatory lumbar spine surgery. Spine (Phila Pa 1976) (2006) 2.11
Predictors of hospital mortality in a population-based cohort of patients with acute lung injury. Crit Care Med (2008) 2.09
Intensive care unit length of stay: Benchmarking based on Acute Physiology and Chronic Health Evaluation (APACHE) IV. Crit Care Med (2006) 2.08
Open-label, follow-on study of azithromycin in pediatric patients with CF uninfected with Pseudomonas aeruginosa. Pediatr Pulmonol (2012) 2.08
Three-year incidence of low back pain in an initially asymptomatic cohort: clinical and imaging risk factors. Spine (Phila Pa 1976) (2005) 2.05
Effect of a rapid response system for patients in shock on time to treatment and mortality during 5 years. Crit Care Med (2007) 2.04
Paraoxonase activity, but not haplotype utilizing the linkage disequilibrium structure, predicts vascular disease. Arterioscler Thromb Vasc Biol (2003) 2.01
Short-term improvements in disability mediate patient satisfaction after epidural corticosteroid injections for symptomatic lumbar spinal stenosis. Spine (Phila Pa 1976) (2015) 1.97
The association between body mass index and clinical outcomes in acute lung injury. Chest (2007) 1.96
Partly conditional survival models for longitudinal data. Biometrics (2005) 1.94
Development of an index to characterize the "invasiveness" of spine surgery: validation by comparison to blood loss and operative time. Spine (Phila Pa 1976) (2008) 1.94
Vitamin C and E intake is associated with increased paraoxonase activity. Arterioscler Thromb Vasc Biol (2002) 1.93
Hypercapnic acidosis and mortality in acute lung injury. Crit Care Med (2006) 1.93
A multicenter mortality prediction model for patients receiving prolonged mechanical ventilation. Crit Care Med (2012) 1.92
Motor cortex organization after stroke is related to side of stroke and level of recovery. Stroke (2003) 1.91
Use of intravenous infusion sedation among mechanically ventilated patients in the United States. Crit Care Med (2009) 1.90
Studying communication about end-of-life care during the ICU family conference: development of a framework. J Crit Care (2002) 1.90
ICU occupancy and mechanical ventilator use in the United States. Crit Care Med (2013) 1.87
Intensive care unit occupancy and patient outcomes. Crit Care Med (2009) 1.87
Cost and incidence of social comorbidities in low-risk patients with community-acquired pneumonia admitted to a public hospital. Chest (2003) 1.82
Effects of leukoreduced blood on acute lung injury after trauma: a randomized controlled trial. Crit Care Med (2008) 1.82
Cost savings attributable to reductions in intensive care unit length of stay for mechanically ventilated patients. Med Care (2008) 1.81
Variations in rates of tracheostomy in the critically ill trauma patient. Crit Care Med (2006) 1.79
Physician attitudes toward regionalization of adult critical care: a national survey. Crit Care Med (2009) 1.79
Low tidal volume ventilation does not increase sedation use in patients with acute lung injury. Crit Care Med (2005) 1.77
Intensive care unit-acquired neuromyopathy and corticosteroids in survivors of persistent ARDS. Intensive Care Med (2008) 1.76
Multi-modality mediastinal staging for lung cancer among medicare beneficiaries. J Thorac Oncol (2009) 1.76
Critical illness outcomes in specialty versus general intensive care units. Am J Respir Crit Care Med (2009) 1.73
Effect of work-hours regulations on intensive care unit mortality in United States teaching hospitals. Crit Care Med (2009) 1.72
Age-, sex-, and race-based differences among patients enrolled versus not enrolled in acute lung injury clinical trials. Crit Care Med (2010) 1.71
A story of success: continuous quality improvement in cystic fibrosis care in the USA. Thorax (2011) 1.68
Repeat surgery after lumbar decompression for herniated disc: the quality implications of hospital and surgeon variation. Spine J (2011) 1.66
Towards standardized measurement of adverse events in spine surgery: conceptual model and pilot evaluation. BMC Musculoskelet Disord (2006) 1.64
Development of a predictive model for long-term survival after lung transplantation and implications for the lung allocation score. J Heart Lung Transplant (2010) 1.64
Disparities in access to lung transplantation for patients with cystic fibrosis by socioeconomic status. Am J Respir Crit Care Med (2012) 1.64
A new severity of illness scale using a subset of Acute Physiology And Chronic Health Evaluation data elements shows comparable predictive accuracy. Crit Care Med (2013) 1.63
Acute respiratory distress syndrome after trauma: development and validation of a predictive model. Crit Care Med (2012) 1.62
Medicaid prior authorization and controlled-release oxycodone. Med Care (2008) 1.61
Marginal modeling of multilevel binary data with time-varying covariates. Biostatistics (2004) 1.61
Risk of post-lung transplant renal dysfunction in adults with cystic fibrosis. Chest (2012) 1.60
Improving palliative care for patients in the intensive care unit. J Palliat Med (2005) 1.60
Respiratory outbreak of Mycobacterium abscessus subspecies massiliense in a lung transplant and cystic fibrosis center. Am J Respir Crit Care Med (2012) 1.59
Effect of intensive care unit organizational model and structure on outcomes in patients with acute lung injury. Am J Respir Crit Care Med (2007) 1.58
Effect of age on the development of ARDS in trauma patients. Chest (2003) 1.57
Perceived barriers to therapeutic hypothermia for patients resuscitated from cardiac arrest: a qualitative study of emergency department and critical care workers. Crit Care Med (2010) 1.56
Prospective validation of the intensive care unit admission Mortality Probability Model (MPM0-III). Crit Care Med (2009) 1.55
Inter-hospital variability in post-cardiac arrest mortality. Resuscitation (2008) 1.54
Long-term survival after hospitalization for community-acquired and healthcare-associated pneumonia. Respiration (2009) 1.54