Published in Mol Cell Biol on December 01, 1991
Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b. EMBO J (1998) 5.21
Analysis of TALE superclass homeobox genes (MEIS, PBC, KNOX, Iroquois, TGIF) reveals a novel domain conserved between plants and animals. Nucleic Acids Res (1997) 3.26
Meis1, a PBX1-related homeobox gene involved in myeloid leukemia in BXH-2 mice. Mol Cell Biol (1995) 2.89
Meis proteins are major in vivo DNA binding partners for wild-type but not chimeric Pbx proteins. Mol Cell Biol (1997) 2.57
AbdB-like Hox proteins stabilize DNA binding by the Meis1 homeodomain proteins. Mol Cell Biol (1997) 2.56
Hematopoietic, angiogenic and eye defects in Meis1 mutant animals. EMBO J (2004) 2.55
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E2A-Pbx1, the t(1;19) translocation protein of human pre-B-cell acute lymphocytic leukemia, causes acute myeloid leukemia in mice. Mol Cell Biol (1993) 2.12
Cooperative interactions between HOX and PBX proteins mediated by a conserved peptide motif. Mol Cell Biol (1995) 2.11
HOXA9 forms triple complexes with PBX2 and MEIS1 in myeloid cells. Mol Cell Biol (1999) 2.06
Meis1 and pKnox1 bind DNA cooperatively with Pbx1 utilizing an interaction surface disrupted in oncoprotein E2a-Pbx1. Proc Natl Acad Sci U S A (1997) 1.97
The pentapeptide motif of Hox proteins is required for cooperative DNA binding with Pbx1, physically contacts Pbx1, and enhances DNA binding by Pbx1. Mol Cell Biol (1995) 1.93
The novel homeoprotein Prep1 modulates Pbx-Hox protein cooperativity. EMBO J (1998) 1.93
Cell signaling switches HOX-PBX complexes from repressors to activators of transcription mediated by histone deacetylases and histone acetyltransferases. Mol Cell Biol (2000) 1.82
Pbx1 is converted into a transcriptional activator upon acquiring the N-terminal region of E2A in pre-B-cell acute lymphoblastoid leukemia. Proc Natl Acad Sci U S A (1993) 1.81
Both Pbx1 and E2A-Pbx1 bind the DNA motif ATCAATCAA cooperatively with the products of multiple murine Hox genes, some of which are themselves oncogenes. Mol Cell Biol (1995) 1.76
An endocrine-exocrine switch in the activity of the pancreatic homeodomain protein PDX1 through formation of a trimeric complex with PBX1b and MRG1 (MEIS2). Mol Cell Biol (1998) 1.72
The pancreatic islet factor STF-1 binds cooperatively with Pbx to a regulatory element in the somatostatin promoter: importance of the FPWMK motif and of the homeodomain. Mol Cell Biol (1995) 1.71
PBX and MEIS as non-DNA-binding partners in trimeric complexes with HOX proteins. Mol Cell Biol (1999) 1.66
Pbx/Meis deficiencies demonstrate multigenetic origins of congenital heart disease. Circ Res (2008) 1.54
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Identification of a novel vertebrate homeobox gene expressed in haematopoietic cells. Nucleic Acids Res (1992) 1.51
Oncogenic homeodomain transcription factor E2A-Pbx1 activates a novel WNT gene in pre-B acute lymphoblastoid leukemia. Proc Natl Acad Sci U S A (1999) 1.48
The hexapeptide LFPWMR in Hoxb-8 is required for cooperative DNA binding with Pbx1 and Pbx2 proteins. Proc Natl Acad Sci U S A (1995) 1.47
Functional dissection of a transcriptionally active, target-specific Hox-Pbx complex. EMBO J (1997) 1.47
Hypomorphic mutation of the TALE gene Prep1 (pKnox1) causes a major reduction of Pbx and Meis proteins and a pleiotropic embryonic phenotype. Mol Cell Biol (2006) 1.46
Fusion with E2A converts the Pbx1 homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the t(1;19) translocation. Mol Cell Biol (1994) 1.45
An extradenticle-induced conformational change in a HOX protein overcomes an inhibitory function of the conserved hexapeptide motif. EMBO J (1996) 1.44
Hox homeodomain proteins exhibit selective complex stabilities with Pbx and DNA. Nucleic Acids Res (1996) 1.43
Structural determinants within Pbx1 that mediate cooperative DNA binding with pentapeptide-containing Hox proteins: proposal for a model of a Pbx1-Hox-DNA complex. Mol Cell Biol (1996) 1.40
PBX3 is an important cofactor of HOXA9 in leukemogenesis. Blood (2012) 1.30
p21 is a transcriptional target of HOXA10 in differentiating myelomonocytic cells. Genes Dev (2000) 1.29
Functional and regulatory interactions between Hox and extradenticle genes. Genes Dev (1998) 1.23
Pbx3 deficiency results in central hypoventilation. Am J Pathol (2004) 1.22
The TALE homeodomain protein Pbx2 is not essential for development and long-term survival. Mol Cell Biol (2004) 1.21
DNA-binding and transcriptional regulatory properties of hepatic leukemia factor (HLF) and the t(17;19) acute lymphoblastic leukemia chimera E2A-HLF. Mol Cell Biol (1994) 1.14
E2a-Pbx1 induces aberrant expression of tissue-specific and developmentally regulated genes when expressed in NIH 3T3 fibroblasts. Mol Cell Biol (1997) 1.13
Pbx-1 Hox heterodimers bind DNA on inseparable half-sites that permit intrinsic DNA binding specificity of the Hox partner at nucleotides 3' to a TAAT motif. Nucleic Acids Res (1996) 1.10
Pbx raises the DNA binding specificity but not the selectivity of antennapedia Hox proteins. Mol Cell Biol (1997) 1.10
Hox and Pbx factors control retinoic acid synthesis during hindbrain segmentation. Dev Cell (2011) 1.07
Biochemistry of the tale transcription factors PREP, MEIS, and PBX in vertebrates. Dev Dyn (2013) 1.07
Prep1 deficiency induces protection from diabetes and increased insulin sensitivity through a p160-mediated mechanism. Mol Cell Biol (2008) 1.07
The Groucho-related gene family regulates the gonadotropin-releasing hormone gene through interaction with the homeodomain proteins MSX1 and OCT1. J Biol Chem (2005) 1.06
TALE homeodomain proteins regulate gonadotropin-releasing hormone gene expression independently and via interactions with Oct-1. J Biol Chem (2004) 1.04
Fine mapping of the nail-patella syndrome locus at 9q34. Am J Hum Genet (1997) 1.03
The Hox cooperativity motif of the chimeric oncoprotein E2a-Pbx1 is necessary and sufficient for oncogenesis. Mol Cell Biol (1997) 1.02
Regulation of PBX3 expression by androgen and Let-7d in prostate cancer. Mol Cancer (2011) 1.00
Identification and analysis of a Saccharomyces cerevisiae copper homeostasis gene encoding a homeodomain protein. Mol Cell Biol (1994) 0.99
pbx is required for pole and eye regeneration in planarians. Development (2013) 0.95
Selective repression of transcriptional activators by Pbx1 does not require the homeodomain. Proc Natl Acad Sci U S A (1996) 0.93
Transformation by homeobox genes can be mediated by selective transcriptional repression. EMBO J (1994) 0.93
Cross-talk between glucocorticoid and retinoic acid signals involving glucocorticoid receptor interaction with the homoeodomain protein Pbx1. Biochem J (2003) 0.93
Pbx homeodomain proteins: TALEnted regulators of limb patterning and outgrowth. Dev Dyn (2011) 0.89
HOXA/PBX3 knockdown impairs growth and sensitizes cytogenetically normal acute myeloid leukemia cells to chemotherapy. Haematologica (2013) 0.89
Conformational changes induced in Hoxb-8/Pbx-1 heterodimers in solution and upon interaction with specific DNA. Mol Cell Biol (1997) 0.88
Hox regulation of transcription: more complex(es). Dev Dyn (2013) 0.88
EWSR1-PBX3: a novel gene fusion in myoepithelial tumors. Genes Chromosomes Cancer (2014) 0.88
Explorative data analysis of MCL reveals gene expression networks implicated in survival and prognosis supported by explorative CGH analysis. BMC Cancer (2008) 0.87
Genetic alterations of hepatocellular carcinoma by random amplified polymorphic DNA analysis and cloning sequencing of tumor differential DNA fragment. World J Gastroenterol (2005) 0.85
Isolation and characterization of the chicken homeodomain protein AKR. Nucleic Acids Res (1995) 0.84
HOX cofactors expression and regulation in the human ovary. Reprod Biol Endocrinol (2008) 0.82
MEIS1, PREP1, and PBX4 are differentially expressed in acute lymphoblastic leukemia: association of MEIS1 expression with higher proliferation and chemotherapy resistance. J Exp Clin Cancer Res (2011) 0.80
Immunocytochemical detection of HoxD9 and Pbx1 homeodomain protein expression in Chinese esophageal squamous cell carcinomas. World J Gastroenterol (2005) 0.79
Dysregulation of RBFOX2 Is an Early Event in Cardiac Pathogenesis of Diabetes. Cell Rep (2016) 0.79
Comparative study of efficacy of dopaminergic neuron differentiation between embryonic stem cell and protein-based induced pluripotent stem cell. PLoS One (2014) 0.79
Induction of tolerance to immunogenic tumor antigens associated with lymphomagenesis in HOX11 transgenic mice. Proc Natl Acad Sci U S A (2000) 0.76
Fusion of the genes EWSR1 and PBX3 in retroperitoneal leiomyoma with t(9;22)(q33;q12). PLoS One (2015) 0.76
PBX3 promotes gastric cancer invasion and metastasis by inducing epithelial-mesenchymal transition. Oncol Lett (2016) 0.75
The CYP2B2 phenobarbital response unit contains binding sites for hepatocyte nuclear factor 4, PBX-PREP1, the thyroid hormone receptor beta and the liver X receptor. Biochem J (2005) 0.75
New nucleotide sequence data on the EMBL File Server. Nucleic Acids Res (1992) 0.75
Silencing Pre-B-cell leukemia homeobox 3 decreases the proliferation of human glioma cells in vitro and in vivo. J Neurooncol (2017) 0.75
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The human t(1;19) translocation in pre-B ALL produces multiple nuclear E2A-Pbx1 fusion proteins with differing transforming potentials. Genes Dev (1991) 2.34
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Structure of two genes at the gooseberry locus related to the paired gene and their spatial expression during Drosophila embryogenesis. Genes Dev (1987) 2.07
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Requirement for Pbx1 in skeletal patterning and programming chondrocyte proliferation and differentiation. Development (2001) 2.33
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