Published in Ann N Y Acad Sci on April 01, 2006
Review of Signaling Pathways Governing MSC Osteogenic and Adipogenic Differentiation. Scientifica (Cairo) (2013) 1.51
Congenic mice provide in vivo evidence for a genetic locus that modulates intrinsic transforming growth factor β1-mediated signaling and bone acquisition. J Bone Miner Res (2012) 1.41
VACTERL/caudal regression/Currarino syndrome-like malformations in mice with mutation in the proprotein convertase Pcsk5. Genes Dev (2008) 1.32
Akt promotes BMP2-mediated osteoblast differentiation and bone development. J Cell Sci (2009) 1.31
TGF-β/BMP signaling and other molecular events: regulation of osteoblastogenesis and bone formation. Bone Res (2015) 1.12
Selective signaling by Akt2 promotes bone morphogenetic protein 2-mediated osteoblast differentiation. Mol Cell Biol (2009) 1.12
Signal transduction and transcriptional regulation during mesenchymal cell differentiation. J Bone Miner Metab (2008) 1.10
Pbx1 represses osteoblastogenesis by blocking Hoxa10-mediated recruitment of chromatin remodeling factors. Mol Cell Biol (2010) 1.09
Heterotopic mineralization (ossification or calcification) in tendinopathy or following surgical tendon trauma. Int J Exp Pathol (2012) 1.07
Vessel formation is induced prior to the appearance of cartilage in BMP-2-mediated heterotopic ossification. J Bone Miner Res (2010) 1.03
Insulin-like growth factor-binding protein-5 inhibits osteoblast differentiation and skeletal growth by blocking insulin-like growth factor actions. Mol Endocrinol (2008) 1.01
Gene expression analyses of subchondral bone in early experimental osteoarthritis by microarray. PLoS One (2012) 1.00
Molecular mechanisms of mesenchymal stem cell differentiation towards osteoblasts. World J Stem Cells (2013) 0.98
Low-level laser therapy induces the expressions of BMP-2, osteocalcin, and TGF-β1 in hypoxic-cultured human osteoblasts. Lasers Med Sci (2012) 0.97
Transcriptomic and phenotypic analysis of murine embryonic stem cell derived BMP2+ lineage cells: an insight into mesodermal patterning. Genome Biol (2007) 0.96
Serum response factor regulates bone formation via IGF-1 and Runx2 signals. J Bone Miner Res (2012) 0.95
In situ tissue regeneration: chemoattractants for endogenous stem cell recruitment. Tissue Eng Part B Rev (2013) 0.87
Polymorphisms in the HOXD4 gene are not associated with peak bone mineral density in Chinese nuclear families. Acta Pharmacol Sin (2010) 0.84
Identification of novel gene expression in healing fracture callus tissue by DNA microarray. HSS J (2008) 0.83
Proteomics approaches for the studies of bone metabolism. BMB Rep (2014) 0.82
Time series gene expression profiling and temporal regulatory pathway analysis of BMP6 induced osteoblast differentiation and mineralization. BMC Syst Biol (2011) 0.81
Combined inhibition of the BMP pathway and the RANK-RANKL axis in a mixed lytic/blastic prostate cancer lesion. Bone (2010) 0.80
Anabolic and Antiresorptive Modulation of Bone Homeostasis by the Epigenetic Modulator Sulforaphane, a Naturally Occurring Isothiocyanate. J Biol Chem (2016) 0.79
Bone morphogenetic proteins and their antagonists: current and emerging clinical uses. Br J Pharmacol (2014) 0.79
FGFR3 induces degradation of BMP type I receptor to regulate skeletal development. Biochim Biophys Acta (2014) 0.78
Acute-phase protein serum amyloid A3 is a novel paracrine coupling factor that controls bone homeostasis. FASEB J (2014) 0.78
Roles of bone morphogenetic protein signaling in osteosarcoma. Int Orthop (2014) 0.78
Tribute to Dr. Marshall Urist: musculoskeletal growth factors: editorial comment. Clin Orthop Relat Res (2009) 0.76
Non-myogenic Contribution to Muscle Development and Homeostasis: The Role of Connective Tissues. Front Cell Dev Biol (2017) 0.75
Molecular Therapy for Degenerative Disc Disease: Clues from Secretome Analysis of the Notochordal Cell-Rich Nucleus Pulposus. Sci Rep (2017) 0.75
Depletion of MEIS2 inhibits osteogenic differentiation potential of human dental stem cells. Int J Clin Exp Med (2015) 0.75
Effects of Remifentanil Preconditioning on Osteoblasts under Hypoxia-Reoxygenation Condition. Int J Med Sci (2015) 0.75
Crystallization and preliminary X-ray analysis of the complex of the first von Willebrand type C domain bound to bone morphogenetic protein 2. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.75
(+)-Cholesten-3-one induces osteogenic differentiation of bone marrow mesenchymal stem cells by activating vitamin D receptor. Exp Ther Med (2017) 0.75
Peripheral denervation participates in heterotopic ossification in a spinal cord injury model. PLoS One (2017) 0.75
A recurrent mutation in bone morphogenetic proteins-2-inducible kinase gene is associated with developmental dysplasia of the hip. Exp Ther Med (2017) 0.75
TGF-beta1-induced migration of bone mesenchymal stem cells couples bone resorption with formation. Nat Med (2009) 4.58
The meaning, the sense and the significance: translating the science of mesenchymal stem cells into medicine. Nat Med (2013) 4.32
Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis. Nat Med (2013) 2.74
Atrial natriuretic peptide inhibits transforming growth factor beta-induced Smad signaling and myofibroblast transformation in mouse cardiac fibroblasts. Circ Res (2007) 2.32
Parathyroid hormone signaling through low-density lipoprotein-related protein 6. Genes Dev (2008) 2.22
BMP signaling in skeletal development. Biochem Biophys Res Commun (2005) 2.13
GADD34-PP1c recruited by Smad7 dephosphorylates TGFbeta type I receptor. J Cell Biol (2004) 1.98
Exome sequencing reveals mutations in TRPV3 as a cause of Olmsted syndrome. Am J Hum Genet (2012) 1.91
Endofin acts as a Smad anchor for receptor activation in BMP signaling. J Cell Sci (2007) 1.81
Deficiency of cathepsin S attenuates angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-deficient mice. Cardiovasc Res (2012) 1.71
Reciprocal roles of MSX2 in regulation of osteoblast and adipocyte differentiation. J Biol Chem (2004) 1.64
Inhibition of Sca-1-positive skeletal stem cell recruitment by alendronate blunts the anabolic effects of parathyroid hormone on bone remodeling. Cell Stem Cell (2010) 1.60
Jab1 antagonizes TGF-beta signaling by inducing Smad4 degradation. EMBO Rep (2002) 1.42
A membrane form of TNF-alpha presented by exosomes delays T cell activation-induced cell death. J Immunol (2006) 1.36
TGF-beta type II receptor phosphorylates PTH receptor to integrate bone remodelling signalling. Nat Cell Biol (2010) 1.33
A glucocorticoid-induced leucine-zipper protein, GILZ, inhibits adipogenesis of mesenchymal cells. EMBO Rep (2003) 1.27
Parathyroid hormone induces differentiation of mesenchymal stromal/stem cells by enhancing bone morphogenetic protein signaling. J Bone Miner Res (2012) 1.22
A dishevelled-1/Smad1 interaction couples WNT and bone morphogenetic protein signaling pathways in uncommitted bone marrow stromal cells. J Biol Chem (2006) 1.22
Selective disruption of high sensitivity heat activation but not capsaicin activation of TRPV1 channels by pore turret mutations. J Gen Physiol (2012) 1.21
Smads oppose Hox transcriptional activities. Exp Cell Res (2006) 1.15
Multiplicity of BMP signaling in skeletal development. Ann N Y Acad Sci (2007) 1.15
Smad4 protein stability is regulated by ubiquitin ligase SCF beta-TrCP1. J Biol Chem (2004) 1.11
Sustained BMP signaling in osteoblasts stimulates bone formation by promoting angiogenesis and osteoblast differentiation. J Bone Miner Res (2009) 1.11
R-spondin1 synergizes with Wnt3A in inducing osteoblast differentiation and osteoprotegerin expression. FEBS Lett (2008) 1.11
MicroRNA-188 regulates age-related switch between osteoblast and adipocyte differentiation. J Clin Invest (2015) 1.10
A nuclear antagonistic mechanism of inhibitory Smads in transforming growth factor-beta signaling. J Biol Chem (2001) 1.09
Bone marrow mesenchymal stem cells and TGF-β signaling in bone remodeling. J Clin Invest (2014) 1.08
Injury-activated transforming growth factor β controls mobilization of mesenchymal stem cells for tissue remodeling. Stem Cells (2012) 1.08
Smad4 as a transcription corepressor for estrogen receptor alpha. J Biol Chem (2003) 1.07
ANP signaling inhibits TGF-beta-induced Smad2 and Smad3 nuclear translocation and extracellular matrix expression in rat pulmonary arterial smooth muscle cells. J Appl Physiol (1985) (2006) 1.05
Smad7 stabilizes beta-catenin binding to E-cadherin complex and promotes cell-cell adhesion. J Biol Chem (2008) 1.03
LRP6 mediates cAMP generation by G protein-coupled receptors through regulating the membrane targeting of Gα(s). Sci Signal (2011) 1.02
The effect of thiazolidinediones on BMD and osteoporosis. Nat Clin Pract Endocrinol Metab (2008) 1.02
Heteromeric heat-sensitive transient receptor potential channels exhibit distinct temperature and chemical response. J Biol Chem (2011) 1.01
Disruption of LRP6 in osteoblasts blunts the bone anabolic activity of PTH. J Bone Miner Res (2013) 0.98
Molecules mimicking Smad1 interacting with Hox stimulate bone formation. J Biol Chem (2003) 0.97
SCF(beta-TrCP1) controls Smad4 protein stability in pancreatic cancer cells. Am J Pathol (2005) 0.96
Four and half lim protein 2 (FHL2) stimulates osteoblast differentiation. J Bone Miner Res (2005) 0.96
Targeting osteoclast-osteoblast communication. Nat Med (2011) 0.95
PDGF induces osteoprotegerin expression in vascular smooth muscle cells by multiple signal pathways. FEBS Lett (2002) 0.95
Dual effects of TGF-beta on ERalpha-mediated estrogenic transcriptional activity in breast cancer. Mol Cancer (2009) 0.95
Regulation of Hex gene expression by a Smads-dependent signaling pathway. J Biol Chem (2002) 0.94
Control of prostate cell growth: BMP antagonizes androgen mitogenic activity with incorporation of MAPK signals in Smad1. EMBO J (2006) 0.94
N-fertilization has different effects on the growth, carbon and nitrogen physiology, and wood properties of slow- and fast-growing Populus species. J Exp Bot (2012) 0.93
Comparison of fetal and adult marrow stromal cells in osteogenesis with and without glucocorticoids. Connect Tissue Res (2006) 0.92
The identification of CD163 expressing phagocytic chondrocytes in joint cartilage and its novel scavenger role in cartilage degradation. PLoS One (2013) 0.90
Function of matrix IGF-1 in coupling bone resorption and formation. J Mol Med (Berl) (2013) 0.90
MAP estimation with structural priors for fluorescence molecular tomography. Phys Med Biol (2012) 0.90
Jab1 mediates protein degradation of the Rad9-Rad1-Hus1 checkpoint complex. J Mol Biol (2007) 0.90
Acute myelogenous leukemia-derived SMAD4 mutations target the protein to ubiquitin-proteasome degradation. Hum Mutat (2006) 0.89
Deprenyl prevents MPP(+)-induced oxidative damage in PC12 cells by the upregulation of Nrf2-mediated NQO1 expression through the activation of PI3K/Akt and Erk. Toxicology (2011) 0.89
TGFbeta/BMP inhibits the bone marrow transformation capability of Hoxa9 by repressing its DNA-binding ability. EMBO J (2006) 0.88
A TRPV4 channel C-terminal folding recognition domain critical for trafficking and function. J Biol Chem (2013) 0.88
Mesenchymal stem cells recruited by active TGFβ contribute to osteogenic vascular calcification. Stem Cells Dev (2014) 0.88
Inhibition of Kaposi's sarcoma-associated herpesvirus lytic replication by HIV-1 Nef and cellular microRNA hsa-miR-1258. J Virol (2014) 0.87
Divalent cations activate TRPV1 through promoting conformational change of the extracellular region. J Gen Physiol (2013) 0.86
Greedy reconstruction algorithm for fluorescence molecular tomography by means of truncated singular value decomposition conversion. J Opt Soc Am A Opt Image Sci Vis (2013) 0.85
Prevalence and features of fatty liver detected by physical examination in Guangzhou. World J Gastroenterol (2013) 0.85
JAB1 determines the response of rheumatoid arthritis synovial fibroblasts to tumor necrosis factor-alpha. Am J Pathol (2006) 0.85
Smad4 inhibits tumor growth by inducing apoptosis in estrogen receptor-alpha-positive breast cancer cells. J Biol Chem (2005) 0.85
Novel mutations of the lipoprotein lipase gene associated with hypertriglyceridemia in members of type 2 diabetic pedigrees. J Lipid Res (2007) 0.85
Role of TGF-β in a mouse model of high turnover renal osteodystrophy. J Bone Miner Res (2014) 0.85
Early-photon fluorescence tomography of a heterogeneous mouse model with the telegraph equation. Appl Opt (2011) 0.84
Fast reconstruction of fluorescence molecular tomography via a permissible region extraction strategy. J Opt Soc Am A Opt Image Sci Vis (2014) 0.83
Keratin K18 increases cystic fibrosis transmembrane conductance regulator (CFTR) surface expression by binding to its C-terminal hydrophobic patch. J Biol Chem (2012) 0.83
Intensity Enhanced Cerenkov Luminescence Imaging Using Terbium-Doped Gd2O2S Microparticles. ACS Appl Mater Interfaces (2015) 0.83
BMP signaling and HOX transcription factors in limb development. Front Biosci (2003) 0.81
Cysteine protease cathepsins and matrix metalloproteinases in the development of abdominal aortic aneurysms. Future Cardiol (2013) 0.81
1,5-dicaffeoylquinic acid protects primary neurons from amyloid β 1-42-induced apoptosis via PI3K/Akt signaling pathway. Chin Med J (Engl) (2011) 0.81
Enhanced nutrient removal in a modified step feed process treating municipal wastewater with different inflow distribution ratios and nutrient ratios. Bioresour Technol (2010) 0.81
Apoptotic role of TGF-β mediated by Smad4 mitochondria translocation and cytochrome c oxidase subunit II interaction. Exp Cell Res (2011) 0.80
Combined Cathepsin S and hs-CRP predicting inflammation of abdominal aortic aneurysm. Clin Biochem (2013) 0.80
Antagonists of LRP6 regulate PTH-induced cAMP generation. Ann N Y Acad Sci (2011) 0.80
Gene 33 inhibits apoptosis of breast cancer cells and increases poly(ADP-ribose) polymerase expression. Breast Cancer Res Treat (2005) 0.80
Characterization of the promoter elements and transcription profile of Periplaneta fuliginosa densovirus nonstructural genes. Virus Res (2008) 0.79
A hybrid reconstruction algorithm for fluorescence tomography using Kirchhoff approximation and finite element method. Med Biol Eng Comput (2012) 0.79
Increased fracture risk and low bone mineral density in patients with loeys-dietz syndrome. Am J Med Genet A (2013) 0.79
Crystal structure of the N-terminal ankyrin repeat domain of TRPV3 reveals unique conformation of finger 3 loop critical for channel function. Protein Cell (2013) 0.79
Assessment of the estrogenic activities of chickpea (Cicer arietinum L) sprout isoflavone extract in ovariectomized rats. Acta Pharmacol Sin (2013) 0.79
PTH receptor signaling in osteoblasts regulates endochondral vascularization in maintenance of postnatal growth plate. J Bone Miner Res (2015) 0.78
Visceral hyperalgesia induced by forebrain-specific suppression of native Kv7/KCNQ/M-current in mice. Mol Pain (2011) 0.78
Monitoring of tumor response to cisplatin by subsurface fluorescence molecular tomography. J Biomed Opt (2012) 0.78
Expression of AIF and HtrA2/Omi in small lymphocytic lymphoma and diffuse large B-cell lymphoma. Arch Pathol Lab Med (2011) 0.78
A novel degradation signal derived from distal C-terminal frameshift mutations of KCNQ2 protein which cause neonatal epilepsy. J Biol Chem (2011) 0.78
Acceleration of early-photon fluorescence molecular tomography with graphics processing units. Comput Math Methods Med (2013) 0.78
The complete nucleotide sequence of the type 5 Helicoverpa armigera cytoplasmic polyhedrosis virus genome. Virus Genes (2008) 0.78
Generation of a mouse model with expression of bone morphogenetic protein type II receptor lacking the cytoplasmic domain in osteoblasts. Ann N Y Acad Sci (2010) 0.78
Generation of isolated sub-10-attosecond pulses in spatially inhomogenous two-color fields. Opt Express (2014) 0.78
Cell death pathways in astrocytes with a modified model of oxygen-glucose deprivation. PLoS One (2013) 0.77
Experimental Tibetan monkey domestication and its application for intraocular pressure measurement. Int J Ophthalmol (2012) 0.77
A meta-analysis of mood stabilizers for Alzheimer's disease. J Huazhong Univ Sci Technolog Med Sci (2010) 0.77
Reconstruction of fluorescence molecular tomography using a neighborhood regularization. IEEE Trans Biomed Eng (2012) 0.77
A novel MYOC heterozygous mutation identified in a Chinese Uygur pedigree with primary open-angle glaucoma. Mol Vis (2012) 0.77
The use of transformed IMR90 cell model to identify the potential extra-telomeric effects of hTERT in cell migration and DNA damage response. BMC Biochem (2014) 0.77
Ex vivo transfer of the Hoxc-8-interacting domain of Smad1 by a tropism-modified adenoviral vector results in efficient bone formation in a rabbit model of spinal fusion. J Spinal Disord Tech (2010) 0.76
Machining variability impacts on the strength of a 'chair-side' CAD-CAM ceramic. Dent Mater (2012) 0.76
[Cervical perivascular sympathectomy for the treatment of athetoid cerebral palsy]. Zhongguo Gu Shang (2010) 0.76
Extrarenal nephroblastomatosis in children: a report of two cases. BMC Pediatr (2014) 0.75
Crystallization and preliminary X-ray analysis of Escherichia coli RNase G. Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 0.75