Published in Neuron on July 20, 2006
Single-vesicle imaging reveals that synaptic vesicle exocytosis and endocytosis are coupled by a single stochastic mode. Proc Natl Acad Sci U S A (2007) 2.65
Inhibition of dynamin completely blocks compensatory synaptic vesicle endocytosis. Proc Natl Acad Sci U S A (2006) 2.61
Two pathways of synaptic vesicle retrieval revealed by single-vesicle imaging. Neuron (2009) 2.38
Synaptic vesicle endocytosis. Cold Spring Harb Perspect Biol (2012) 1.84
Synaptophysin regulates the kinetics of synaptic vesicle endocytosis in central neurons. Neuron (2011) 1.71
Synaptic vesicle recycling at CNS snapses without AP-2. J Neurosci (2009) 1.69
Protein scaffolds in the coupling of synaptic exocytosis and endocytosis. Nat Rev Neurosci (2011) 1.61
v-SNARE composition distinguishes synaptic vesicle pools. Neuron (2011) 1.54
A heterogeneous "resting" pool of synaptic vesicles that is dynamically interchanged across boutons in mammalian CNS synapses. Brain Cell Biol (2008) 1.51
Molecular genetics and imaging technologies for circuit-based neuroanatomy. Nature (2009) 1.51
Protein quantification at the single vesicle level reveals that a subset of synaptic vesicle proteins are trafficked with high precision. J Neurosci (2011) 1.44
Exocytosis and endocytosis: modes, functions, and coupling mechanisms. Annu Rev Physiol (2013) 1.33
Synaptic vesicle pools: an update. Front Synaptic Neurosci (2010) 1.27
Two synaptobrevin molecules are sufficient for vesicle fusion in central nervous system synapses. Proc Natl Acad Sci U S A (2011) 1.27
Uncoupling the roles of synaptotagmin I during endo- and exocytosis of synaptic vesicles. Nat Neurosci (2011) 1.26
Two forms of single-vesicle astrocyte exocytosis imaged with total internal reflection fluorescence microscopy. Proc Natl Acad Sci U S A (2007) 1.21
Mechanism and function of synaptotagmin-mediated membrane apposition. Nat Struct Mol Biol (2011) 1.19
TRPM7 facilitates cholinergic vesicle fusion with the plasma membrane. Proc Natl Acad Sci U S A (2008) 1.17
SNARE proteins synaptobrevin, SNAP-25, and syntaxin are involved in rapid and slow endocytosis at synapses. Cell Rep (2013) 1.13
Palmitoyl protein thioesterase-1 deficiency impairs synaptic vesicle recycling at nerve terminals, contributing to neuropathology in humans and mice. J Clin Invest (2008) 1.12
Synaptic vesicle recycling: steps and principles. EMBO J (2014) 1.08
Exchange and redistribution dynamics of the cytoskeleton of the active zone molecule bassoon. J Neurosci (2009) 1.08
Synaptic vesicle protein trafficking at the glutamate synapse. Neuroscience (2008) 1.06
Synapsin IIa controls the reserve pool of glutamatergic synaptic vesicles. J Neurosci (2008) 1.06
Imaging phluorin-based probes at hippocampal synapses. Methods Mol Biol (2008) 1.02
Vesicular monoamine and glutamate transporters select distinct synaptic vesicle recycling pathways. J Neurosci (2010) 1.02
A distributed set of interactions controls mu2 functionality in the role of AP-2 as a sorting adaptor in synaptic vesicle endocytosis. J Biol Chem (2009) 0.97
Post-fusion structural changes and their roles in exocytosis and endocytosis of dense-core vesicles. Nat Commun (2014) 0.96
A genetically specified connectomics approach applied to long-range feeding regulatory circuits. Nat Neurosci (2014) 0.96
Axonal and dendritic synaptotagmin isoforms revealed by a pHluorin-syt functional screen. Mol Biol Cell (2012) 0.94
Clathrin-mediated endocytosis: the physiological mechanism of vesicle retrieval at hippocampal synapses. J Physiol (2007) 0.93
Clathrin-mediated endocytosis at the synaptic terminal: bridging the gap between physiology and molecules. Traffic (2010) 0.92
Photolysis of a caged peptide reveals rapid action of N-ethylmaleimide sensitive factor before neurotransmitter release. Proc Natl Acad Sci U S A (2008) 0.92
Imaging the post-fusion release and capture of a vesicle membrane protein. Nat Commun (2012) 0.91
Study of neurotrophin-3 signaling in primary cultured neurons using multiplex stable isotope labeling with amino acids in cell culture. J Proteome Res (2011) 0.91
Stimulation-induced formation of the reserve pool of vesicles in Drosophila motor boutons. J Neurophysiol (2009) 0.91
Compromised fidelity of endocytic synaptic vesicle protein sorting in the absence of stonin 2. Proc Natl Acad Sci U S A (2013) 0.90
Molecular mechanisms of COMPLEXIN fusion clamp function in synaptic exocytosis revealed in a new Drosophila mutant. Mol Cell Neurosci (2013) 0.90
Recruitment of sphingosine kinase to presynaptic terminals by a conserved muscarinic signaling pathway promotes neurotransmitter release. Genes Dev (2012) 0.90
Botulinum neurotoxin serotype C associates with dual ganglioside receptors to facilitate cell entry. J Biol Chem (2012) 0.88
Glycosylation is dispensable for sorting of synaptotagmin 1 but is critical for targeting of SV2 and synaptophysin to recycling synaptic vesicles. J Biol Chem (2012) 0.88
High- and low-mobility stages in the synaptic vesicle cycle. Biophys J (2010) 0.88
Synaptophysin I selectively specifies the exocytic pathway of synaptobrevin 2/VAMP2. Biochem J (2007) 0.88
The spatial pattern of exocytosis and post-exocytic mobility of synaptopHluorin in mouse motor nerve terminals. J Physiol (2009) 0.87
Preferred sites of exocytosis and endocytosis colocalize during high- but not lower-frequency stimulation in mouse motor nerve terminals. J Neurosci (2009) 0.87
Munc18-1 redistributes in nerve terminals in an activity- and PKC-dependent manner. J Cell Biol (2014) 0.87
Genetic approaches to reveal the connectivity of adult-born neurons. Front Neurosci (2011) 0.86
VAMP2 interacts directly with the N terminus of Kv2.1 to enhance channel inactivation. Pflugers Arch (2008) 0.86
A membrane pool retrieved via endocytosis overshoot at nerve terminals: a study of its retrieval mechanism and role. J Neurosci (2012) 0.86
Dance of the SNAREs: assembly and rearrangements detected with FRET at neuronal synapses. J Neurosci (2013) 0.85
Cholesterol and F-actin are required for clustering of recycling synaptic vesicle proteins in the presynaptic plasma membrane. J Physiol (2013) 0.84
GABA(A) receptors can initiate the formation of functional inhibitory GABAergic synapses. Eur J Neurosci (2013) 0.83
The GTPase Rab26 links synaptic vesicles to the autophagy pathway. Elife (2015) 0.82
Vesicular glutamate transporter 1 orchestrates recruitment of other synaptic vesicle cargo proteins during synaptic vesicle recycling. J Biol Chem (2015) 0.81
'Fractional recovery' analysis of a presynaptic synaptotagmin 1-anchored endocytic protein complex. PLoS One (2006) 0.81
Distinct modes of endocytotic presynaptic membrane and protein uptake at the calyx of Held terminal of rats and mice. Elife (2016) 0.81
Overlapping functions of stonin 2 and SV2 in sorting of the calcium sensor synaptotagmin 1 to synaptic vesicles. Proc Natl Acad Sci U S A (2015) 0.80
Synaptic vesicle morphology: a case of protein sorting? Curr Opin Cell Biol (2013) 0.80
Structure parameters of synaptic vesicles quantified by small-angle x-ray scattering. Biophys J (2010) 0.80
Diffusional spread and confinement of newly exocytosed synaptic vesicle proteins. Nat Commun (2015) 0.80
Regulation of presynaptic anchoring of the scaffold protein Bassoon by phosphorylation-dependent interaction with 14-3-3 adaptor proteins. PLoS One (2013) 0.79
AP180 couples protein retrieval to clathrin-mediated endocytosis of synaptic vesicles. Traffic (2014) 0.79
The fate of synaptic vesicle components upon fusion. Commun Integr Biol (2010) 0.79
Botulinum Neurotoxins Can Enter Cultured Neurons Independent of Synaptic Vesicle Recycling. PLoS One (2015) 0.78
Fluorescent probes for monitoring regulated secretion. Curr Opin Chem Biol (2013) 0.77
Protons Regulate Vesicular Glutamate Transporters through an Allosteric Mechanism. Neuron (2016) 0.77
Different dynamin blockers interfere with distinct phases of synaptic endocytosis during stimulation in motoneurones. J Physiol (2015) 0.77
Protein interactions of the vesicular glutamate transporter VGLUT1. PLoS One (2014) 0.76
The Active and Periactive Zone Organization and the Functional Properties of Small and Large Synapses. Front Synaptic Neurosci (2016) 0.76
Visualizing Presynaptic Calcium Dynamics and Vesicle Fusion with a Single Genetically Encoded Reporter at Individual Synapses. Front Synaptic Neurosci (2016) 0.75
Differential targeting of dynamin-1 and dynamin-3 to nerve terminals during chronic suppression of neuronal activity. Mol Cell Neurosci (2015) 0.75
Mixing and matching during synaptic vesicle endocytosis. Neuron (2006) 0.75
Dynamic properties of the alkaline vesicle population at hippocampal synapses. PLoS One (2014) 0.75
Probes for monitoring regulated exocytosis. Cell Calcium (2017) 0.75
A selective activity-dependent requirement for dynamin 1 in synaptic vesicle endocytosis. Science (2007) 4.86
Actin has a molecular scaffolding, not propulsive, role in presynaptic function. Nat Neurosci (2003) 3.06
Impaired PtdIns(4,5)P2 synthesis in nerve terminals produces defects in synaptic vesicle trafficking. Nature (2004) 2.81
The dual phosphatase activity of synaptojanin1 is required for both efficient synaptic vesicle endocytosis and reavailability at nerve terminals. Neuron (2007) 2.36
The kinetics of synaptic vesicle pool depletion at CNS synaptic terminals. Neuron (2004) 2.29
Molecular circuitry of endocytosis at nerve terminals. Annu Rev Cell Dev Biol (2009) 2.22
CDK5 serves as a major control point in neurotransmitter release. Neuron (2010) 2.21
Decreased synaptic vesicle recycling efficiency and cognitive deficits in amphiphysin 1 knockout mice. Neuron (2002) 2.21
Synaptic vesicle mobilization is regulated by distinct synapsin I phosphorylation pathways at different frequencies. Neuron (2003) 2.04
α2δ expression sets presynaptic calcium channel abundance and release probability. Nature (2012) 1.90
Calcium control of endocytic capacity at a CNS synapse. J Neurosci (2008) 1.76
The kinetics of synaptic vesicle reacidification at hippocampal nerve terminals. J Neurosci (2006) 1.75
Synaptic vesicle recycling at CNS snapses without AP-2. J Neurosci (2009) 1.69
Modes of vesicle retrieval at ribbon synapses, calyx-type synapses, and small central synapses. J Neurosci (2007) 1.66
Neural activity controls the synaptic accumulation of alpha-synuclein. J Neurosci (2005) 1.62
The synaptic vesicle: cycle of exocytosis and endocytosis. Curr Opin Neurobiol (2006) 1.55
A heterogeneous "resting" pool of synaptic vesicles that is dynamically interchanged across boutons in mammalian CNS synapses. Brain Cell Biol (2008) 1.51
Overlapping role of dynamin isoforms in synaptic vesicle endocytosis. Neuron (2011) 1.49
Kinetic efficiency of endocytosis at mammalian CNS synapses requires synaptotagmin I. Proc Natl Acad Sci U S A (2004) 1.45
Targeted chemical disruption of clathrin function in living cells. Mol Biol Cell (2003) 1.43
Regulation of neurotransmitter release by synapsin III. J Neurosci (2002) 1.34
Roscovitine: a novel regulator of P/Q-type calcium channels and transmitter release in central neurons. J Physiol (2002) 1.32
The efficiency of the synaptic vesicle cycle at central nervous system synapses. Trends Cell Biol (2006) 1.31
Highly cooperative control of endocytosis by clathrin. Mol Biol Cell (2005) 1.21
Dynamin phosphorylation controls optimization of endocytosis for brief action potential bursts. Elife (2013) 1.19
Syntaxin-1A is excluded from recycling synaptic vesicles at nerve terminals. J Neurosci (2004) 1.10
Balance of calcineurin Aα and CDK5 activities sets release probability at nerve terminals. J Neurosci (2013) 1.09
Optical mapping of release properties in synapses. Front Neural Circuits (2010) 1.07
The general anesthetic isoflurane depresses synaptic vesicle exocytosis. Mol Pharmacol (2005) 1.06
A distributed set of interactions controls mu2 functionality in the role of AP-2 as a sorting adaptor in synaptic vesicle endocytosis. J Biol Chem (2009) 0.97
Intrinsic variability in Pv, RRP size, Ca(2+) channel repertoire, and presynaptic potentiation in individual synaptic boutons. Front Synaptic Neurosci (2013) 0.97
Live imaging of synaptic vesicle release and retrieval in dopaminergic neurons. Front Neural Circuits (2009) 0.97
Synaptic vesicle retrieval time is a cell-wide rather than individual-synapse property. Nat Neurosci (2011) 0.92
A system for performing high throughput assays of synaptic function. PLoS One (2011) 0.91
New insights into molecular players involved in neurotransmitter release. Physiology (Bethesda) (2012) 0.86
Calbindin controls release probability in ventral tegmental area dopamine neurons. Nat Neurosci (2012) 0.84
Munc18-dependent regulation of synaptic vesicle exocytosis by syntaxin-1A in hippocampal neurons. Neuropharmacology (2005) 0.84
Working memory impairment in calcineurin knock-out mice is associated with alterations in synaptic vesicle cycling and disruption of high-frequency synaptic and network activity in prefrontal cortex. J Neurosci (2013) 0.82
Telomere length and the clinical phenotype of frailty in older adults undergoing cardiac surgery. J Am Geriatr Soc (2014) 0.76
Synaptic UNC13A protein variant causes increased neurotransmission and dyskinetic movement disorder. J Clin Invest (2017) 0.75
Neuronal protein economics: keeping tabs on synthesis. Nat Neurosci (2010) 0.75
Fluorescent proteins with ties that bind. Nat Biotechnol (2003) 0.75