PubRank

Timothy A Ryan

Author PubWeight™ 64.93‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A selective activity-dependent requirement for dynamin 1 in synaptic vesicle endocytosis. Science 2007 4.86
2 Actin has a molecular scaffolding, not propulsive, role in presynaptic function. Nat Neurosci 2003 3.06
3 Impaired PtdIns(4,5)P2 synthesis in nerve terminals produces defects in synaptic vesicle trafficking. Nature 2004 2.81
4 Synaptic vesicles interchange their membrane proteins with a large surface reservoir during recycling. Neuron 2006 2.75
5 The dual phosphatase activity of synaptojanin1 is required for both efficient synaptic vesicle endocytosis and reavailability at nerve terminals. Neuron 2007 2.36
6 The kinetics of synaptic vesicle pool depletion at CNS synaptic terminals. Neuron 2004 2.29
7 Molecular circuitry of endocytosis at nerve terminals. Annu Rev Cell Dev Biol 2009 2.22
8 CDK5 serves as a major control point in neurotransmitter release. Neuron 2010 2.21
9 Decreased synaptic vesicle recycling efficiency and cognitive deficits in amphiphysin 1 knockout mice. Neuron 2002 2.21
10 Synaptic vesicle mobilization is regulated by distinct synapsin I phosphorylation pathways at different frequencies. Neuron 2003 2.04
11 α2δ expression sets presynaptic calcium channel abundance and release probability. Nature 2012 1.90
12 Calcium control of endocytic capacity at a CNS synapse. J Neurosci 2008 1.76
13 The kinetics of synaptic vesicle reacidification at hippocampal nerve terminals. J Neurosci 2006 1.75
14 Synaptic vesicle recycling at CNS snapses without AP-2. J Neurosci 2009 1.69
15 Modes of vesicle retrieval at ribbon synapses, calyx-type synapses, and small central synapses. J Neurosci 2007 1.66
16 Neural activity controls the synaptic accumulation of alpha-synuclein. J Neurosci 2005 1.62
17 The synaptic vesicle: cycle of exocytosis and endocytosis. Curr Opin Neurobiol 2006 1.55
18 A heterogeneous "resting" pool of synaptic vesicles that is dynamically interchanged across boutons in mammalian CNS synapses. Brain Cell Biol 2008 1.51
19 Overlapping role of dynamin isoforms in synaptic vesicle endocytosis. Neuron 2011 1.49
20 Kinetic efficiency of endocytosis at mammalian CNS synapses requires synaptotagmin I. Proc Natl Acad Sci U S A 2004 1.45
21 Targeted chemical disruption of clathrin function in living cells. Mol Biol Cell 2003 1.43
22 Regulation of neurotransmitter release by synapsin III. J Neurosci 2002 1.34
23 Roscovitine: a novel regulator of P/Q-type calcium channels and transmitter release in central neurons. J Physiol 2002 1.32
24 The efficiency of the synaptic vesicle cycle at central nervous system synapses. Trends Cell Biol 2006 1.31
25 Highly cooperative control of endocytosis by clathrin. Mol Biol Cell 2005 1.21
26 Dynamin phosphorylation controls optimization of endocytosis for brief action potential bursts. Elife 2013 1.19
27 Syntaxin-1A is excluded from recycling synaptic vesicles at nerve terminals. J Neurosci 2004 1.10
28 Balance of calcineurin Aα and CDK5 activities sets release probability at nerve terminals. J Neurosci 2013 1.09
29 Optical mapping of release properties in synapses. Front Neural Circuits 2010 1.07
30 The general anesthetic isoflurane depresses synaptic vesicle exocytosis. Mol Pharmacol 2005 1.06
31 A distributed set of interactions controls mu2 functionality in the role of AP-2 as a sorting adaptor in synaptic vesicle endocytosis. J Biol Chem 2009 0.97
32 Intrinsic variability in Pv, RRP size, Ca(2+) channel repertoire, and presynaptic potentiation in individual synaptic boutons. Front Synaptic Neurosci 2013 0.97
33 Live imaging of synaptic vesicle release and retrieval in dopaminergic neurons. Front Neural Circuits 2009 0.97
34 Synaptic vesicle retrieval time is a cell-wide rather than individual-synapse property. Nat Neurosci 2011 0.92
35 A system for performing high throughput assays of synaptic function. PLoS One 2011 0.91
36 New insights into molecular players involved in neurotransmitter release. Physiology (Bethesda) 2012 0.86
37 Calbindin controls release probability in ventral tegmental area dopamine neurons. Nat Neurosci 2012 0.84
38 Munc18-dependent regulation of synaptic vesicle exocytosis by syntaxin-1A in hippocampal neurons. Neuropharmacology 2005 0.84
39 Working memory impairment in calcineurin knock-out mice is associated with alterations in synaptic vesicle cycling and disruption of high-frequency synaptic and network activity in prefrontal cortex. J Neurosci 2013 0.82
40 Fluorescent proteins with ties that bind. Nat Biotechnol 2003 0.75
41 Neuronal protein economics: keeping tabs on synthesis. Nat Neurosci 2010 0.75
42 Synaptic UNC13A protein variant causes increased neurotransmission and dyskinetic movement disorder. J Clin Invest 2017 0.75