Published in Proc Natl Acad Sci U S A on July 18, 2006
Stimulation of the insulin/mTOR pathway delays cone death in a mouse model of retinitis pigmentosa. Nat Neurosci (2008) 2.94
HDAC4 regulates neuronal survival in normal and diseased retinas. Science (2009) 1.86
Antioxidant or neurotrophic factor treatment preserves function in a mouse model of neovascularization-associated oxidative stress. J Clin Invest (2009) 1.51
A Naturally-Derived Compound Schisandrin B Enhanced Light Sensation in the pde6c Zebrafish Model of Retinal Degeneration. PLoS One (2016) 1.39
CNTF induces regeneration of cone outer segments in a rat model of retinal degeneration. PLoS One (2010) 1.39
Increased expression of catalase and superoxide dismutase 2 reduces cone cell death in retinitis pigmentosa. Mol Ther (2009) 1.37
Receptor interacting protein kinase mediates necrotic cone but not rod cell death in a mouse model of inherited degeneration. Proc Natl Acad Sci U S A (2012) 1.37
NADPH oxidase plays a central role in cone cell death in retinitis pigmentosa. J Neurochem (2009) 1.32
Loss of daylight vision in retinal degeneration: are oxidative stress and metabolic dysregulation to blame? J Biol Chem (2011) 1.31
Impaired cone function and cone degeneration resulting from CNGB3 deficiency: down-regulation of CNGA3 biosynthesis as a potential mechanism. Hum Mol Genet (2009) 1.30
Improved retinal function in a mouse model of dominant retinitis pigmentosa following AAV-delivered gene therapy. Mol Ther (2009) 1.29
Oxidative stress promotes ocular neovascularization. J Cell Physiol (2009) 1.28
ER stress in retinal degeneration in S334ter Rho rats. PLoS One (2012) 1.27
Rod-derived cone viability factor for treating blinding diseases: from clinic to redox signaling. Sci Transl Med (2010) 1.20
Gene and noncoding RNA regulation underlying photoreceptor protection: microarray study of dietary antioxidant saffron and photobiomodulation in rat retina. Mol Vis (2010) 1.20
Increased expression of glutathione peroxidase 4 strongly protects retina from oxidative damage. Antioxid Redox Signal (2009) 1.15
Overexpression of SOD in retina: need for increase in H2O2-detoxifying enzyme in same cellular compartment. Free Radic Biol Med (2011) 1.14
Aag-initiated base excision repair drives alkylation-induced retinal degeneration in mice. Proc Natl Acad Sci U S A (2009) 1.09
Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/βA3/A1-crystallin via V-ATPase-MTORC1 signaling. Autophagy (2014) 1.08
Calpain and PARP activation during photoreceptor cell death in P23H and S334ter rhodopsin mutant rats. PLoS One (2011) 1.08
Retinal dysfunction and progressive retinal cell death in SOD1-deficient mice. Am J Pathol (2008) 1.07
Activation of bone marrow-derived microglia promotes photoreceptor survival in inherited retinal degeneration. Am J Pathol (2008) 1.06
Blockade of neuronal nitric oxide synthase reduces cone cell death in a model of retinitis pigmentosa. Free Radic Biol Med (2008) 1.06
NRF2 promotes neuronal survival in neurodegeneration and acute nerve damage. J Clin Invest (2015) 1.05
Retinal expression of Fgf2 in RCS rats with subretinal microphotodiode array. Invest Ophthalmol Vis Sci (2009) 1.04
Activated mTORC1 promotes long-term cone survival in retinitis pigmentosa mice. J Clin Invest (2015) 1.03
Nanoceria extend photoreceptor cell lifespan in tubby mice by modulation of apoptosis/survival signaling pathways. Neurobiol Dis (2011) 1.02
Gene therapy restores vision in rd1 mice after removal of a confounding mutation in Gpr179. Nat Commun (2015) 1.02
Preservation of cone photoreceptors after a rapid yet transient degeneration and remodeling in cone-only Nrl-/- mouse retina. J Neurosci (2012) 1.00
Deletion of the p85alpha regulatory subunit of phosphoinositide 3-kinase in cone photoreceptor cells results in cone photoreceptor degeneration. Invest Ophthalmol Vis Sci (2011) 1.00
Early-onset, slow progression of cone photoreceptor dysfunction and degeneration in CNG channel subunit CNGB3 deficiency. Invest Ophthalmol Vis Sci (2011) 0.98
The homeobox gene CHX10/VSX2 regulates RdCVF promoter activity in the inner retina. Hum Mol Genet (2009) 0.97
Rod and cone photoreceptor cells produce ROS in response to stress in a live retinal explant system. Mol Vis (2010) 0.96
The thioredoxin-like protein rod-derived cone viability factor (RdCVFL) interacts with TAU and inhibits its phosphorylation in the retina. Mol Cell Proteomics (2009) 0.96
Glutathione peroxidase 4 is required for maturation of photoreceptor cells. J Biol Chem (2011) 0.96
Altered antioxidant-oxidant status in the aqueous humor and peripheral blood of patients with retinitis pigmentosa. PLoS One (2013) 0.96
Edaravone, an ROS scavenger, ameliorates photoreceptor cell death after experimental retinal detachment. Invest Ophthalmol Vis Sci (2011) 0.94
Reprogramming of adult rod photoreceptors prevents retinal degeneration. Proc Natl Acad Sci U S A (2013) 0.94
Vascular cell-adhesion molecule-1 plays a central role in the proangiogenic effects of oxidative stress. Proc Natl Acad Sci U S A (2011) 0.94
Is There Excess Oxidative Stress and Damage in Eyes of Patients with Retinitis Pigmentosa? Antioxid Redox Signal (2015) 0.94
Sustained delivery of a HIF-1 antagonist for ocular neovascularization. J Control Release (2013) 0.92
Constituents of bile, bilirubin and TUDCA, protect against oxidative stress-induced retinal degeneration. J Neurochem (2010) 0.91
Experimental scleral cross-linking increases glaucoma damage in a mouse model. Exp Eye Res (2014) 0.90
Prolonged blockade of VEGF receptors does not damage retinal photoreceptors or ganglion cells. J Cell Physiol (2010) 0.90
Suppressing thyroid hormone signaling preserves cone photoreceptors in mouse models of retinal degeneration. Proc Natl Acad Sci U S A (2014) 0.90
Evaluation of potential therapies for a mouse model of human age-related macular degeneration caused by delayed all-trans-retinal clearance. Invest Ophthalmol Vis Sci (2009) 0.90
N-acetylcysteine amide (NACA) prevents retinal degeneration by up-regulating reduced glutathione production and reversing lipid peroxidation. Am J Pathol (2011) 0.88
Emerging gene therapies for retinal degenerations. J Neurosci (2012) 0.87
Potential implication of the chemical properties and bioactivity of nitrone spin traps for therapeutics. Future Med Chem (2012) 0.86
Safranal, a saffron constituent, attenuates retinal degeneration in P23H rats. PLoS One (2012) 0.86
RIP kinase-mediated necrosis as an alternative mechanisms of photoreceptor death. Oncotarget (2011) 0.85
Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors. PLoS Genet (2013) 0.85
Functional rescue of cone photoreceptors in retinitis pigmentosa. Graefes Arch Clin Exp Ophthalmol (2013) 0.85
Green tea extract suppresses N-methyl-N-nitrosourea-induced photoreceptor apoptosis in Sprague-Dawley rats. Graefes Arch Clin Exp Ophthalmol (2014) 0.85
Systemic administration of the antioxidant/iron chelator α-lipoic acid protects against light-induced photoreceptor degeneration in the mouse retina. Invest Ophthalmol Vis Sci (2014) 0.85
Review: the history and role of naturally occurring mouse models with Pde6b mutations. Mol Vis (2013) 0.85
Characteristics of rod regeneration in a novel zebrafish retinal degeneration model using N-methyl-N-nitrosourea (MNU). PLoS One (2013) 0.84
Activation of the molecular chaperone, sigma 1 receptor, preserves cone function in a murine model of inherited retinal degeneration. Proc Natl Acad Sci U S A (2016) 0.84
Retinitis pigmentosa and ocular blood flow. EPMA J (2012) 0.83
Long-term expression of glial cell line-derived neurotrophic factor slows, but does not stop retinal degeneration in a model of retinitis pigmentosa. J Neurochem (2012) 0.83
Evidence supporting a role for N-(3-formyl-3,4-dehydropiperidino)lysine accumulation in Müller glia dysfunction and death in diabetic retinopathy. Mol Vis (2010) 0.83
Progress toward effective treatments for human photoreceptor degenerations. Curr Opin Genet Dev (2009) 0.83
℮-conome: an automated tissue counting platform of cone photoreceptors for rodent models of retinitis pigmentosa. BMC Ophthalmol (2011) 0.82
Prevention of retinal light damage by zinc oxide combined with rosemary extract. Mol Vis (2013) 0.81
CNGA3 deficiency affects cone synaptic terminal structure and function and leads to secondary rod dysfunction and degeneration. Invest Ophthalmol Vis Sci (2012) 0.81
Proinsulin slows retinal degeneration and vision loss in the P23H rat model of retinitis pigmentosa. Hum Gene Ther (2012) 0.81
Retinal vessel oxygen saturation and vessel diameter in retinitis pigmentosa at various ages. Graefes Arch Clin Exp Ophthalmol (2015) 0.81
Association of retinal vessel attenuation with visual function in eyes with retinitis pigmentosa. Clin Ophthalmol (2014) 0.81
Cytochrome P450 2C epoxygenases mediate photochemical stress-induced death of photoreceptors. J Biol Chem (2014) 0.80
Retinal structure and function preservation by polysaccharides of wolfberry in a mouse model of retinal degeneration. Sci Rep (2014) 0.80
A possible role of acrolein in diabetic retinopathy: involvement of a VEGF/TGFβ signaling pathway of the retinal pigment epithelium in hyperglycemia. Curr Eye Res (2012) 0.80
The synthetic progestin norgestrel modulates Nrf2 signaling and acts as an antioxidant in a model of retinal degeneration. Redox Biol (2016) 0.79
A profile of transcriptomic changes in the rd10 mouse model of retinitis pigmentosa. Mol Vis (2014) 0.79
The synthetic progestin norgestrel acts to increase LIF levels in the rd10 mouse model of retinitis pigmentosa. Mol Vis (2016) 0.79
MRI of Retinal Free Radical Production With Laminar Resolution In Vivo. Invest Ophthalmol Vis Sci (2016) 0.79
Degeneration modulates retinal response to transient exogenous oxidative injury. PLoS One (2014) 0.78
Effects of calcium ion, calpains, and calcium channel blockers on retinitis pigmentosa. J Ophthalmol (2010) 0.78
Infliximab reduces Zaprinast-induced retinal degeneration in cultures of porcine retina. J Neuroinflammation (2014) 0.78
Gene therapy to rescue retinal degeneration caused by mutations in rhodopsin. Methods Mol Biol (2015) 0.78
Differential alterations in the expression of neurotransmitter receptors in inner retina following loss of photoreceptors in rd1 mouse. PLoS One (2015) 0.78
Mn porphyrin-based SOD mimic, MnTnHex-2-PyP(5+), and non-SOD mimic, MnTBAP(3-), suppressed rat spinal cord ischemia/reperfusion injury via NF-κB pathways. Free Radic Res (2014) 0.78
Expression of leukemia inhibitory factor in Müller glia cells is regulated by a redox-dependent mRNA stability mechanism. BMC Biol (2015) 0.77
Cell metabolism: Sugar for sight. Nature (2015) 0.77
Anthocyanin can arrest the cone photoreceptor degeneration and act as a novel treatment for retinitis pigmentosa. Int J Ophthalmol (2016) 0.76
Measuring In Vivo Free Radical Production by the Outer Retina. Invest Ophthalmol Vis Sci (2015) 0.76
NADPH Oxidase Contributes to Photoreceptor Degeneration in Constitutively Active RAC1 Mice. Invest Ophthalmol Vis Sci (2016) 0.76
Management of Ocular Diseases Using Lutein and Zeaxanthin: What Have We Learned from Experimental Animal Studies? J Ophthalmol (2015) 0.76
Exploiting metabolic and antioxidant pathways to maintain vision in blinding disease. J Clin Invest (2015) 0.76
A short N-terminal domain of HDAC4 preserves photoreceptors and restores visual function in retinitis pigmentosa. Nat Commun (2015) 0.76
Metabolic and redox signaling in the retina. Cell Mol Life Sci (2016) 0.75
Protective effects of SS31 on t‑BHP induced oxidative damage in 661W cells. Mol Med Rep (2015) 0.75
Fundus Camera-Delivered Light-Induced Retinal Degeneration in Mice With the RPE65 Leu450Met Variant is Associated With Oxidative Stress and Apoptosis. Invest Ophthalmol Vis Sci (2016) 0.75
Advances in Gene Therapy for Diseases of the Eye. Hum Gene Ther (2016) 0.75
Quantifying the metabolic contribution to photoreceptor death in retinitis pigmentosa via a mathematical model. J Theor Biol (2016) 0.75
Inhibition of LPS-induced retinal microglia activation by naloxone does not prevent photoreceptor death. Inflammation (2013) 0.75
MUTYH promotes oxidative microglial activation and inherited retinal degeneration. JCI Insight (2016) 0.75
Adult Human Peripheral Blood Mononuclear Cells Are Capable of Producing Neurocyte or Photoreceptor-Like Cells That Survive in Mouse Eyes After Preinduction With Neonatal Retina. Stem Cells Transl Med (2016) 0.75
Targeting iodothyronine deiodinases locally in the retina is a therapeutic strategy for retinal degeneration. FASEB J (2016) 0.75
The temporal topography of the N-Methyl- N-nitrosourea induced photoreceptor degeneration in mouse retina. Sci Rep (2015) 0.75
Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic Biol Med (1991) 16.01
A novel neurological phenotype in mice lacking mitochondrial manganese superoxide dismutase. Nat Genet (1998) 3.41
Differential effect of the rd mutation on rods and cones in the mouse retina. Invest Ophthalmol Vis Sci (1978) 3.30
Identification of 4-hydroxynonenal as a cytotoxic product originating from the peroxidation of liver microsomal lipids. Biochim Biophys Acta (1980) 2.89
Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease. Proc Natl Acad Sci U S A (1996) 2.88
Activated microglia in human retinitis pigmentosa, late-onset retinal degeneration, and age-related macular degeneration. Exp Eye Res (2003) 2.73
Identification and characterization of rod-derived cone viability factor. Nat Genet (2004) 2.63
Protein-bound acrolein: potential markers for oxidative stress. Proc Natl Acad Sci U S A (1998) 2.42
Carbonyl modified proteins in cellular regulation, aging, and disease. Free Radic Biol Med (2002) 2.23
Protein carbonyl measurement by a sensitive ELISA method. Free Radic Biol Med (1997) 2.14
Ascorbic acid treatment corrects the phenotype of a mouse model of Charcot-Marie-Tooth disease. Nat Med (2004) 1.86
Oxidative damage is a potential cause of cone cell death in retinitis pigmentosa. J Cell Physiol (2005) 1.73
A metalloporphyrin superoxide dismutase mimetic protects against paraquat-induced endothelial cell injury, in vitro. J Pharmacol Exp Ther (1995) 1.70
Intraretinal oxygen levels before and after photoreceptor loss in the RCS rat. Invest Ophthalmol Vis Sci (2000) 1.65
Effect of long-term administration of alpha-lipoic acid on retinal capillary cell death and the development of retinopathy in diabetic rats. Diabetes (2004) 1.62
Histopathology of bone spicule pigmentation in retinitis pigmentosa. Ophthalmology (1995) 1.45
Increased expression of brain-derived neurotrophic factor preserves retinal function and slows cell death from rhodopsin mutation or oxidative damage. J Neurosci (2003) 1.44
Protein-bound acrolein: a novel marker of oxidative stress in Alzheimer's disease. J Neurochem (1999) 1.42
Variability in rate of cone degeneration in the retinal degeneration (rd/rd) mouse. Exp Eye Res (1997) 1.41
Cell death in retinitis pigmentosa: gap junctions and the 'bystander' effect. Exp Eye Res (2002) 1.38
Vasohibin is up-regulated by VEGF in the retina and suppresses VEGF receptor 2 and retinal neovascularization. FASEB J (2006) 1.35
Effects of different types of oxidative stress in RPE cells. J Cell Physiol (2006) 1.32
Photoreceptor death, trophic factor expression, retinal oxygen status, and photoreceptor function in the P23H rat. Invest Ophthalmol Vis Sci (2004) 1.31
Dose-dependent protection by lipoic acid against cisplatin-induced nephrotoxicity in rats: antioxidant defense system. Pharmacol Toxicol (2000) 1.19
Histochemical detection of 4-hydroxynonenal protein in Alzheimer amyloid. J Neurol Sci (1998) 1.16
Hyperoxia causes decreased expression of vascular endothelial growth factor and endothelial cell apoptosis in adult retina. J Cell Physiol (1999) 1.14
Fibroblast growth factor-2 decreases hyperoxia-induced photoreceptor cell death in mice. Am J Pathol (2001) 1.11
Concurrent administration of coenzyme Q10 and alpha-tocopherol improves learning in aged mice. Free Radic Biol Med (2005) 1.10
Vascular atrophy in the retinal degenerative rd mouse. J Comp Neurol (1986) 1.10
A metalloporphyrin superoxide dismutase mimetic protects against paraquat-induced lung injury in vivo. Toxicol Appl Pharmacol (1996) 1.03
Vitamins C and E downregulate vascular VEGF and VEGFR-2 expression in apolipoprotein-E-deficient mice. Atherosclerosis (2003) 0.95
The free radical scavenger, alpha-lipoic acid, protects against cerebral ischemia-reperfusion injury in gerbils. Free Radic Res (1995) 0.92
Endogenous ascorbate regenerates vitamin E in the retina directly and in combination with exogenous dihydrolipoic acid. Curr Eye Res (1995) 0.88
Cortical representation of retinal degeneration. Adv Exp Med Biol (1977) 0.81
Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by Angiopoietin-1. Dev Cell (2002) 6.41
Ranibizumab for macular edema following central retinal vein occlusion: six-month primary end point results of a phase III study. Ophthalmology (2010) 4.60
Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration. Proc Natl Acad Sci U S A (2010) 4.30
Seven new loci associated with age-related macular degeneration. Nat Genet (2013) 3.81
Two-year outcomes of the ranibizumab for edema of the mAcula in diabetes (READ-2) study. Ophthalmology (2010) 3.49
Cell type-specific regulation of angiogenic growth factor gene expression and induction of angiogenesis in nonischemic tissue by a constitutively active form of hypoxia-inducible factor 1. Circ Res (2003) 3.34
Primary End Point (Six Months) Results of the Ranibizumab for Edema of the mAcula in diabetes (READ-2) study. Ophthalmology (2009) 2.77
Sustained benefits from ranibizumab for macular edema following branch retinal vein occlusion: 12-month outcomes of a phase III study. Ophthalmology (2011) 2.65
Vascular endothelial growth factor is a critical stimulus for diabetic macular edema. Am J Ophthalmol (2006) 2.50
Ranibizumab for macular edema due to retinal vein occlusions: long-term follow-up in the HORIZON trial. Ophthalmology (2012) 2.36
Pigment epithelium-derived factor suppresses ischemia-induced retinal neovascularization and VEGF-induced migration and growth. Invest Ophthalmol Vis Sci (2002) 2.03
Antioxidants slow photoreceptor cell death in mouse models of retinitis pigmentosa. J Cell Physiol (2007) 2.00
MicroRNAs regulate ocular neovascularization. Mol Ther (2008) 1.89
Oxidative damage is a potential cause of cone cell death in retinitis pigmentosa. J Cell Physiol (2005) 1.73
VEGF-TRAP(R1R2) suppresses choroidal neovascularization and VEGF-induced breakdown of the blood-retinal barrier. J Cell Physiol (2003) 1.71
Inducible expression of vascular endothelial growth factor in adult mice causes severe proliferative retinopathy and retinal detachment. Am J Pathol (2002) 1.59
AAV-mediated gene transfer of pigment epithelium-derived factor inhibits choroidal neovascularization. Invest Ophthalmol Vis Sci (2002) 1.58
Ranibizumab for edema of the macula in diabetes study: 3-year outcomes and the need for prolonged frequent treatment. JAMA Ophthalmol (2013) 1.55
Angiopoietin-2 plays an important role in retinal angiogenesis. J Cell Physiol (2002) 1.50
The SDF-1/CXCR4 ligand/receptor pair is an important contributor to several types of ocular neovascularization. FASEB J (2007) 1.49
Intraoperative ketorolac and eye pain after viteoretinal surgery: a prospective, randomized, placebo-controlled study. Retina (2003) 1.46
Increased expression of brain-derived neurotrophic factor preserves retinal function and slows cell death from rhodopsin mutation or oxidative damage. J Neurosci (2003) 1.44
Analysis of the VMD2 promoter and implication of E-box binding factors in its regulation. J Biol Chem (2004) 1.41
In vivo immunostaining demonstrates macrophages associate with growing and regressing vessels. Invest Ophthalmol Vis Sci (2007) 1.40
Increased expression of catalase and superoxide dismutase 2 reduces cone cell death in retinitis pigmentosa. Mol Ther (2009) 1.37
Comparison between retinal thickness analyzer and optical coherence tomography for assessment of foveal thickness in eyes with macular disease. Am J Ophthalmol (2002) 1.36
Vasohibin is up-regulated by VEGF in the retina and suppresses VEGF receptor 2 and retinal neovascularization. FASEB J (2006) 1.35
Oxidative stress modulates complement factor H expression in retinal pigmented epithelial cells by acetylation of FOXO3. J Biol Chem (2007) 1.34
Identification of gene expression changes associated with the progression of retinal degeneration in the rd1 mouse. Invest Ophthalmol Vis Sci (2004) 1.33
Effects of different types of oxidative stress in RPE cells. J Cell Physiol (2006) 1.32
NADPH oxidase plays a central role in cone cell death in retinitis pigmentosa. J Neurochem (2009) 1.32
Digoxin inhibits retinal ischemia-induced HIF-1alpha expression and ocular neovascularization. FASEB J (2010) 1.31
A functional variant in the CFI gene confers a high risk of age-related macular degeneration. Nat Genet (2013) 1.29
Oxidative stress promotes ocular neovascularization. J Cell Physiol (2009) 1.28
Implication of the hypoxia response element of the Vegf promoter in mouse models of retinal and choroidal neovascularization, but not retinal vascular development. J Cell Physiol (2006) 1.28
Superoxide dismutase 1 protects retinal cells from oxidative damage. J Cell Physiol (2006) 1.27
Vitreous levels of pigment epithelium-derived factor and vascular endothelial growth factor: implications for ocular angiogenesis. Am J Ophthalmol (2004) 1.26
Combined phacoemulsification, intraocular lens implantation, and vitrectomy for eyes with coexisting cataract and vitreoretinal pathology. Am J Ophthalmol (2003) 1.26
A phase I trial of an IV-administered vascular endothelial growth factor trap for treatment in patients with choroidal neovascularization due to age-related macular degeneration. Ophthalmology (2006) 1.23
Supplemental oxygen improves diabetic macular edema: a pilot study. Invest Ophthalmol Vis Sci (2004) 1.20
Quantitative assessment of the integrity of the blood-retinal barrier in mice. Invest Ophthalmol Vis Sci (2002) 1.20
Increased expression of VEGF in retinal pigmented epithelial cells is not sufficient to cause choroidal neovascularization. J Cell Physiol (2004) 1.19
Predictive value in retinal vein occlusions of early versus late or incomplete ranibizumab response defined by optical coherence tomography. Ophthalmology (2013) 1.17
Ophthalmic drug delivery systems for the treatment of retinal diseases: basic research to clinical applications. Invest Ophthalmol Vis Sci (2010) 1.17
Retinal degeneration from oxidative damage. Free Radic Biol Med (2005) 1.17
Topical nepafenac inhibits ocular neovascularization. Invest Ophthalmol Vis Sci (2003) 1.16
Regression of ocular neovascularization in response to increased expression of pigment epithelium-derived factor. Invest Ophthalmol Vis Sci (2002) 1.16
Increased expression of glutathione peroxidase 4 strongly protects retina from oxidative damage. Antioxid Redox Signal (2009) 1.15
Overexpression of SOD in retina: need for increase in H2O2-detoxifying enzyme in same cellular compartment. Free Radic Biol Med (2011) 1.14
A phase I study of intravitreal vascular endothelial growth factor trap-eye in patients with neovascular age-related macular degeneration. Ophthalmology (2009) 1.13
Gene expression variation in the adult human retina. Hum Mol Genet (2003) 1.12
Different effects of angiopoietin-2 in different vascular beds: new vessels are most sensitive. FASEB J (2005) 1.12
Identification of novel genes preferentially expressed in the retina using a custom human retina cDNA microarray. Invest Ophthalmol Vis Sci (2003) 1.11
ADAM9 is involved in pathological retinal neovascularization. Mol Cell Biol (2009) 1.09
Inhibition of protein kinase C decreases prostaglandin-induced breakdown of the blood-retinal barrier. J Cell Physiol (2003) 1.08
Mecamylamine suppresses Basal and nicotine-stimulated choroidal neovascularization. Invest Ophthalmol Vis Sci (2008) 1.06
Prolonged blockade of VEGF family members does not cause identifiable damage to retinal neurons or vessels. J Cell Physiol (2008) 1.06
Blockade of neuronal nitric oxide synthase reduces cone cell death in a model of retinitis pigmentosa. Free Radic Biol Med (2008) 1.06
An anti-nociceptive role for ceftriaxone in chronic neuropathic pain in rats. Pain (2009) 1.05
Ocular gene transfer with self-complementary AAV vectors. Invest Ophthalmol Vis Sci (2007) 1.04
TNF-alpha is critical for ischemia-induced leukostasis, but not retinal neovascularization nor VEGF-induced leakage. J Neuroimmunol (2006) 1.04
Topical administration of a multi-targeted kinase inhibitor suppresses choroidal neovascularization and retinal edema. J Cell Physiol (2008) 1.04
Retina-specific expression of PDGF-B versus PDGF-A: vascular versus nonvascular proliferative retinopathy. Invest Ophthalmol Vis Sci (2002) 1.04
FACS-assisted microarray profiling implicates novel genes and pathways in zebrafish gastrointestinal tract development. Gastroenterology (2009) 1.04
In vivo micropathology of Best macular dystrophy with optical coherence tomography. Exp Eye Res (2003) 1.04
Effects of intraocular ranibizumab and bevacizumab in transgenic mice expressing human vascular endothelial growth factor. Ophthalmology (2009) 1.03
Suppression and regression of choroidal neovascularization by systemic administration of an alpha5beta1 integrin antagonist. Mol Pharmacol (2006) 1.03
Nitric oxide is proangiogenic in the retina and choroid. J Cell Physiol (2002) 1.03
Angiopoietin-2 enhances retinal vessel sensitivity to vascular endothelial growth factor. J Cell Physiol (2004) 1.02
Injury-independent induction of reactive gliosis in retina by loss of function of the LIM homeodomain transcription factor Lhx2. Proc Natl Acad Sci U S A (2012) 1.00
The iron carrier transferrin is upregulated in retinas from patients with age-related macular degeneration. Invest Ophthalmol Vis Sci (2006) 1.00
Targeting VE-PTP activates TIE2 and stabilizes the ocular vasculature. J Clin Invest (2014) 0.99
N-Acetylcysteine promotes long-term survival of cones in a model of retinitis pigmentosa. J Cell Physiol (2011) 0.99
Suppression and regression of choroidal neovascularization by the multitargeted kinase inhibitor pazopanib. Arch Ophthalmol (2009) 0.98
Periocular gene transfer of sFlt-1 suppresses ocular neovascularization and vascular endothelial growth factor-induced breakdown of the blood-retinal barrier. Hum Gene Ther (2003) 0.97
Blockade of sphingosine-1-phosphate reduces macrophage influx and retinal and choroidal neovascularization. J Cell Physiol (2009) 0.97
Dynamic and quantitative analysis of choroidal neovascularization by fluorescein angiography. Invest Ophthalmol Vis Sci (2006) 0.96
VMD2 promoter requires two proximal E-box sites for its activity in vivo and is regulated by the MITF-TFE family. J Biol Chem (2006) 0.96
Impact of optical coherence tomography on surgical decision making for epiretinal membranes and vitreomacular traction. Retina (2007) 0.96
Intraocular injection of an aptamer that binds PDGF-B: a potential treatment for proliferative retinopathies. J Cell Physiol (2006) 0.96
Treatment of macular edema due to retinal vein occlusions. Clin Ophthalmol (2011) 0.95
A method for analysis of gene expression in isolated mouse photoreceptor and Müller cells. Mol Vis (2004) 0.95
Suppression and regression of choroidal neovascularization by polyamine analogues. Invest Ophthalmol Vis Sci (2005) 0.95
Increased expression of glial cell line-derived neurotrophic factor protects against oxidative damage-induced retinal degeneration. J Neurochem (2007) 0.94
Intraocular expression of endostatin reduces VEGF-induced retinal vascular permeability, neovascularization, and retinal detachment. FASEB J (2003) 0.94
Vascular cell-adhesion molecule-1 plays a central role in the proangiogenic effects of oxidative stress. Proc Natl Acad Sci U S A (2011) 0.94
Mutations in the F-box gene LARGER PANICLE improve the panicle architecture and enhance the grain yield in rice. Plant Biotechnol J (2011) 0.93
BEST1 expression in the retinal pigment epithelium is modulated by OTX family members. Hum Mol Genet (2008) 0.93
Small ribosomal protein subunit S7 suppresses ovarian tumorigenesis through regulation of the PI3K/AKT and MAPK pathways. PLoS One (2013) 0.93
Equine infectious anemia viral vector-mediated codelivery of endostatin and angiostatin driven by retinal pigmented epithelium-specific VMD2 promoter inhibits choroidal neovascularization. Hum Gene Ther (2009) 0.92
Combretastatin A-4 phosphate suppresses development and induces regression of choroidal neovascularization. Invest Ophthalmol Vis Sci (2003) 0.92
Adeno-associated virus (AAV) capsid genes isolated from rat and mouse liver genomic DNA define two new AAV species distantly related to AAV-5. Virology (2006) 0.92