Published in Endocrinology on July 20, 2006
Inhibitory effects of leptin on pancreatic alpha-cell function. Diabetes (2009) 1.20
Palosuran inhibits binding to primate UT receptors in cell membranes but demonstrates differential activity in intact cells and vascular tissues. Br J Pharmacol (2008) 0.86
Potential Clinical Implications of the Urotensin II Receptor Antagonists. Front Pharmacol (2011) 0.84
Niclosamide reduces glucagon sensitivity via hepatic PKA inhibition in obese mice: Implications for glucose metabolism improvements in type 2 diabetes. Sci Rep (2017) 0.75
The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis. Neuron (2003) 6.05
A comparison of endoscopic treatment and surgery in early esophageal cancer: an analysis of surveillance epidemiology and end results data. Am J Gastroenterol (2008) 3.54
Ablation of ghrelin improves the diabetic but not obese phenotype of ob/ob mice. Cell Metab (2006) 3.14
Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor. Proc Natl Acad Sci U S A (2004) 2.99
Immunolocalization of estrogen receptor beta in the mouse brain: comparison with estrogen receptor alpha. Endocrinology (2003) 2.85
Deletion of ghrelin impairs neither growth nor appetite. Mol Cell Biol (2003) 2.73
Apo-ghrelin receptor forms heteromers with DRD2 in hypothalamic neurons and is essential for anorexigenic effects of DRD2 agonism. Neuron (2012) 2.30
Mutations in NR4A2 associated with familial Parkinson disease. Nat Genet (2002) 2.27
11beta-HSD1 inhibition ameliorates metabolic syndrome and prevents progression of atherosclerosis in mice. J Exp Med (2005) 2.12
Ghrelin promotes thymopoiesis during aging. J Clin Invest (2007) 1.83
Selective small-molecule agonists of G protein-coupled receptor 40 promote glucose-dependent insulin secretion and reduce blood glucose in mice. Diabetes (2008) 1.72
Des-acyl ghrelin induces food intake by a mechanism independent of the growth hormone secretagogue receptor. Endocrinology (2006) 1.67
Regeneration of diabetic axons is enhanced by selective knockdown of the PTEN gene. Brain (2014) 1.64
Characterization of adult ghrelin and ghrelin receptor knockout mice under positive and negative energy balance. Endocrinology (2007) 1.64
Bisphenol A and other compounds in human saliva and urine associated with the placement of composite restorations. J Am Dent Assoc (2012) 1.61
Ghrelin amplifies dopamine signaling by cross talk involving formation of growth hormone secretagogue receptor/dopamine receptor subtype 1 heterodimers. Mol Endocrinol (2006) 1.53
An age-dependent interaction with leptin unmasks ghrelin's bone-protective effects. Endocrinology (2012) 1.50
Association between tension-type headache and migraine with sleep bruxism: a systematic review. Headache (2014) 1.43
Active ghrelin levels and active to total ghrelin ratio in cancer-induced cachexia. J Clin Endocrinol Metab (2005) 1.42
A role for the melanocortin 4 receptor in sexual function. Proc Natl Acad Sci U S A (2002) 1.38
17 Beta-estradiol-induced antidepressant-like effect in the forced swim test is absent in estrogen receptor-beta knockout (BERKO) mice. Psychopharmacology (Berl) (2005) 1.27
Aging leads to a programmed loss of brown adipocytes in murine subcutaneous white adipose tissue. Aging Cell (2012) 1.26
Cyclin D3 maintains growth-inhibitory activity of C/EBPalpha by stabilizing C/EBPalpha-cdk2 and C/EBPalpha-Brm complexes. Mol Cell Biol (2006) 1.22
Ghrelin and growth hormone secretagogue receptor expression in mice during aging. Endocrinology (2006) 1.18
Desensitization and endocytosis mechanisms of ghrelin-activated growth hormone secretagogue receptor 1a. Endocrinology (2003) 1.17
An essential component in steroid synthesis, the steroidogenic acute regulatory protein, is expressed in discrete regions of the brain. J Neurosci (2002) 1.15
6H-Benzo[c]chromen-6-one derivatives as selective ERbeta agonists. Bioorg Med Chem Lett (2006) 1.11
Triazolo-tetrahydrofluorenones as selective estrogen receptor beta agonists. Bioorg Med Chem Lett (2006) 1.07
Ghrelin prevents cisplatin-induced mechanical hyperalgesia and cachexia. Endocrinology (2007) 1.06
Deficient ghrelin receptor-mediated signaling compromises thymic stromal cell microenvironment by accelerating thymic adiposity. J Biol Chem (2008) 1.06
A fluorescence-based thiol quantification assay for ultra-high-throughput screening for inhibitors of coenzyme A production. Assay Drug Dev Technol (2008) 1.05
Central and peripheral roles of ghrelin on glucose homeostasis. Neuroendocrinology (2007) 1.05
Growth hormone corrects proliferation and transcription of phosphoenolpyruvate carboxykinase in livers of old mice via elimination of CCAAT/enhancer-binding protein alpha-Brm complex. J Biol Chem (2006) 1.03
Modification of ghrelin receptor signaling by somatostatin receptor-5 regulates insulin release. Proc Natl Acad Sci U S A (2012) 1.02
The preproghrelin gene is required for the normal integration of thermoregulation and sleep in mice. Proc Natl Acad Sci U S A (2009) 1.02
Ghrelin is produced in taste cells and ghrelin receptor null mice show reduced taste responsivity to salty (NaCl) and sour (citric acid) tastants. PLoS One (2010) 1.01
The Ca(2+) sensor stromal interaction molecule 1 (STIM1) is necessary and sufficient for the store-operated Ca(2+) entry function of transient receptor potential canonical (TRPC) 1 and 4 channels in endothelial cells. Mol Pharmacol (2011) 1.00
Restricted feeding-induced sleep, activity, and body temperature changes in normal and preproghrelin-deficient mice. Am J Physiol Regul Integr Comp Physiol (2009) 0.99
Acylated and unacylated ghrelin impair skeletal muscle atrophy in mice. J Clin Invest (2013) 0.99
Dynamic plasticity of axons within a cutaneous milieu. J Neurosci (2010) 0.98
Glucagon-like peptide 1, insulin, sensory neurons, and diabetic neuropathy. J Neuropathol Exp Neurol (2012) 0.98
The growth hormone secretagogue receptor. Vitam Horm (2008) 0.97
Unacylated ghrelin rapidly modulates lipogenic and insulin signaling pathway gene expression in metabolically active tissues of GHSR deleted mice. PLoS One (2010) 0.97
Resistance to trophic neurite outgrowth of sensory neurons exposed to insulin. J Neurochem (2012) 0.95
Gastric antisecretory and antiulcer activities of Cedrus deodara (Roxb.) Loud. in Wistar rats. J Ethnopharmacol (2010) 0.95
Discovery of 5-aryloxy-2,4-thiazolidinediones as potent GPR40 agonists. Bioorg Med Chem Lett (2009) 0.95
Schwann cells direct peripheral nerve regeneration through the Netrin-1 receptors, DCC and Unc5H2. Glia (2011) 0.94
Diagnostic capability of questionnaires and clinical examinations to assess sleep-disordered breathing in children: a systematic review and meta-analysis. J Am Dent Assoc (2014) 0.94
Discovery of substituted biphenyl imidazoles as potent, bioavailable bombesin receptor subtype-3 agonists. Bioorg Med Chem Lett (2010) 0.93
Spontaneous sleep and homeostatic sleep regulation in ghrelin knockout mice. Am J Physiol Regul Integr Comp Physiol (2007) 0.93
Activation of melanocortin MC(4) receptors increases erectile activity in rats ex copula. Eur J Pharmacol (2002) 0.93
Somatostatin receptor subtype-2-deficient mice with diet-induced obesity have hyperglycemia, nonfasting hyperglucagonemia, and decreased hepatic glycogen deposition. Endocrinology (2007) 0.92
The chemokine receptors CXCR1 and CXCR2 couple to distinct G protein-coupled receptor kinases to mediate and regulate leukocyte functions. J Immunol (2012) 0.92
Androstenediol analogs as ER-beta-selective SERMs. Bioorg Med Chem Lett (2005) 0.92
Somatostatin receptor subtype 5 regulates insulin secretion and glucose homeostasis. Mol Endocrinol (2003) 0.92
Inhibition of cisplatin-induced lipid catabolism and weight loss by ghrelin in male mice. Endocrinology (2013) 0.91
A mixed mirror-image DNA/RNA aptamer inhibits glucagon and acutely improves glucose tolerance in models of type 1 and type 2 diabetes. J Biol Chem (2013) 0.90
Control of rat tail skin temperature regulation by estrogen receptor-beta selective ligand. Maturitas (2009) 0.88
Estrogen receptor ligands. Part 9: Dihydrobenzoxathiin SERAMs with alkyl substituted pyrrolidine side chains and linkers. Bioorg Med Chem Lett (2005) 0.88
Increased expression of CYP24A1 correlates with advanced stages of prostate cancer and can cause resistance to vitamin D3-based therapies. FASEB J (2013) 0.88
Ghrelin is dispensable for embryonic pancreatic islet development and differentiation. Regul Pept (2009) 0.88
Estrogen receptor ligands. II. Discovery of benzoxathiins as potent, selective estrogen receptor alpha modulators. J Med Chem (2004) 0.87
Physiological roles revealed by ghrelin and ghrelin receptor deficient mice. Peptides (2011) 0.87
Novel 1-(2-aminopyrazin-3-yl)methyl-2-thioureas as potent inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2). Bioorg Med Chem Lett (2009) 0.86
Differential hormonal regulation of tryptophan hydroxylase-2 mRNA in the murine dorsal raphe nucleus. Biol Psychiatry (2005) 0.86
Palmitate has proapoptotic and proinflammatory effects on articular cartilage and synergizes with interleukin-1. Arthritis Rheumatol (2014) 0.86
Brown-to-white transition in subcutaneous fat: linking aging and disease. Aging (Albany NY) (2012) 0.86
Immunomodulatory effects of seabuckthorn (Hippophae rhamnoides L.) against chromium (VI) induced immunosuppression. Mol Cell Biochem (2005) 0.86
Synthesis and evaluation of small libraries of triazolylmethoxy chalcones, flavanones and 2-aminopyrimidines as inhibitors of mycobacterial FAS-II and PknG. Bioorg Med Chem (2012) 0.85
Growth hormone secretagogue receptor (GHS-R1a) knockout mice exhibit improved spatial memory and deficits in contextual memory. Behav Brain Res (2012) 0.85
3-Substituted 3-(4-aryloxyaryl)-propanoic acids as GPR40 agonists. Bioorg Med Chem Lett (2011) 0.85
Design and synthesis of prolylcarboxypeptidase (PrCP) inhibitors to validate PrCP as a potential target for obesity. J Med Chem (2010) 0.85
Pesticide bioaccumulation and plasma sex steroids in fishes during breeding phase from north India. Environ Toxicol Pharmacol (2007) 0.85
Estrogen receptor-beta regulates tryptophan hydroxylase-1 expression in the murine midbrain raphe. Biol Psychiatry (2005) 0.84
Orexin-A inhibits glucagon secretion and gene expression through a Foxo1-dependent pathway. Endocrinology (2007) 0.84
Estrogen receptor ligands. Part 1: The discovery of flavanoids with subtype selectivity. Bioorg Med Chem Lett (2004) 0.84
Characterization of voltage operated R-type Ca2+ channels in modulating somatostatin receptor subtype 2- and 3-dependent inhibition of insulin secretion from INS-1 cells. Cell Signal (2008) 0.84
Cypermethrin induced histological changes in gonadotrophic cells, liver, gonads, plasma levels of estradiol-17beta and 11-ketotestosterone, and sperm motility in Heteropneustes fossilis (Bloch). Chemosphere (2008) 0.83
Antagonist-induced, activation function-2-independent estrogen receptor alpha phosphorylation. Mol Endocrinol (2005) 0.83
Severe hepatotoxicity caused by a methasteron-containing performance-enhancing supplement. J Clin Gastroenterol (2009) 0.83
Study on iron availability from prepared soybean sprouts using an iron-deficient rat model. Food Chem (2012) 0.83
Exendin-4, a GLP-1 receptor agonist, stimulates pituitary-adrenocortical axis in the rat: Investigations into the mechanism(s) underlying Ex4 effect. Int J Mol Med (2003) 0.83
Growth hormone secretagogues modulate the electrical and contractile properties of rat skeletal muscle through a ghrelin-specific receptor. Br J Pharmacol (2003) 0.83
The steroidogenic acute regulatory protein is expressed in steroidogenic cells of the day-old brain. Endocrinology (2004) 0.83